The ideaSpace Podcast: How Startups Actually Get Built

ideaSpace

Real stories from founders and operators on how companies actually get built — from idea to scale and exit. Through interviews, talks and discussions, the ideaSpace Podcast explores the reality of building a business: the decisions, trade-offs, failures and successes. Our Start-up Stories episodes focus on founder journeys, while Business Basics dives into specific topics - from sales and hiring to fundraising and product. Recorded within ideaSpace, the University of Cambridge’s startup community, where founders support each other to build high-impact ventures.

  1. Sep 22

    Why Most Startup Advice Is Wrong - with Matthew Cleevely

    What happens after you build, scale and sell a start-up - and how does the experience change the way you think about entrepreneurship? Matthew Cleevely returns to the ideaSpace Podcast four and a half years after his first appearance, when he was still building 10to8. Since then, he has exited the company and gone on to work with, advise and invest in other founders. He's also written The Founder’s Map: Volume 1: Building the Machine, which brings together the lessons he's learned along the way. In this conversation, Matthew and Ben explore the realities of life after an exit, why so much start-up advice can be misleading, and the uncomfortable role that luck and survivor bias can play. They also dig into some of the less glamorous, but hugely important parts of building a startup: boards and governance, hiring, company culture, documentation and putting the right foundations in place early. Matthew talks candidly about the mistakes he made building 10to8, including a culture that became toxic, the experience of running out of money, and the “phantom stress” that remained even after selling the company. They also discuss the importance of founder communities, why Matthew describes ideaSpace as a “platform, foundation and lifeboat”, and finish with a deceptively simple question: what does it actually mean to be a successful founder? A candid conversation about the bits of entrepreneurship that don't always make it into the success stories. Chapters (00:00:02) - Introduction and Episode Preview(00:01:52) - Catching Up With Matthew Clevely(00:03:07) - The Road to Selling 10 to 8(00:04:19) - Lessons From Selling a Company(00:07:22) - Life After the Exit and Phantom Stress(00:09:36) - Why Most Startup Advice Is Wrong(00:11:48) - Writing the Book as a Cathartic Process(00:14:34) - Privilege, Risk, and the Role of Luck(00:18:15) - The Underestimated Importance of Boards(00:21:05) - Board Stories and Early-Stage Structure(00:24:28) - Company Culture: Definition and Failures(00:29:12) - Rebuilding Culture at 10 to 8(00:31:18) - Hiring as a System That Shapes Culture(00:35:42) - How the Founders Map Book Came Together(00:38:24) - Practical Advice for Founders Right Now(00:39:59) - The Value of Community and IdeaSpace(00:40:54) - Defining a Successful Founder(00:41:45) - Closing Thoughts and the Matthew Bot(00:42:41) - Ben's Reflections and Sign-Off

  2. Feb 20

    Why Founders Shouldn’t Build Alone - with Katie Lewis and Matthew Stafford of 9others

    In this episode of the ideaSpace Podcast, Ben Hartley is joined by Matthew Stafford and Katie Lewis, co-founders of 9others - a global peer network built on a simple but powerful belief: your success requires the help of others. What began as founder–investor dinners in London has grown into intimate monthly gatherings where entrepreneurs come together to answer one honest question: What’s keeping you up at night? Today, 9others spans multiple cities and has supported thousands of founders through trusted relationships, candid conversations, and the strength of community. In this conversation, they explore why founders should build their networks before they need them, common misconceptions about accelerators and fundraising, lessons learned through failure, and why vulnerability may be one of the most underrated leadership strengths. For anyone building something - or considering it - this episode offers practical insight and hard-earned perspective. Matthew Stafford is co-founder of 9others and has spent over a decade working in venture capital and early-stage investing. He supports founders navigating the realities of building high-growth businesses and believes great companies are built not only on capital, but on strong relationships and courageous leadership. He is co-author of Find Your Nine Others. Katie Lewis is co-founder of 9others and has worked across accelerators, venture programmes, and startup ecosystems internationally. She is passionate about helping founders build businesses that solve real problems and create meaningful impact. Katie champions contribution, community, and the power of an abundant mindset. She is co-author of Find Your Nine Others.

    Why Founders Shouldn’t Build Alone - with Katie Lewis and Matthew Stafford of 9others
  3. 06/30/2025

    Building a Biotech: Funding, Commercialisation, and Leading as CEO - with Lluna Gallego Segrelles

    In this Start-up Stories episode, Ben Hartley speaks with Lluna Gallego Segrelles, CEO and co-founder of Vector Bioscience Cambridge - a University of Cambridge spinout developing AI-enabled “nano-shuttle” drug delivery technology designed to improve targeting and reduce side effects, starting in oncology. What you’ll learn in this episode: How a university spinout moves from 10+ years of research into a commercial company - and the trade-offs of building a platform technology What “non-dilutive funding” enabled for Vector, and how early grants can accelerate team-building and momentum How Lluna approached commercialisation as a non-scientist: translating the science into what investors, pharma partners, regulators, and patients need What the CEO role really looks like in an early-stage biotech: business development, partnerships, hiring, strategy, and “connecting the science to the outside world” How to choose a lead product when your technology can do many things (the “platform problem”) Why founder confidence matters - and how Lluna manages imposter syndrome while taking on bigger leadership challenges Why founder communities matter, including Lluna’s work co-founding the Cambridge Female Founders Network to reduce isolation and support women-led ventures What’s next for Vector: expanding the team and labs, progressing lead candidates, and preparing for their first fundraise About the guest: Lluna Gallego Segrelles is the CEO and co-founder of Vector Bioscience Cambridge, a biotech spinout from the University of Cambridge. She also co-founded the Cambridge Female Founders Network, supporting a more inclusive entrepreneurial ecosystem.

    Building a Biotech: Funding, Commercialisation, and Leading as CEO - with Lluna Gallego Segrelles

About

Real stories from founders and operators on how companies actually get built — from idea to scale and exit. Through interviews, talks and discussions, the ideaSpace Podcast explores the reality of building a business: the decisions, trade-offs, failures and successes. Our Start-up Stories episodes focus on founder journeys, while Business Basics dives into specific topics - from sales and hiring to fundraising and product. Recorded within ideaSpace, the University of Cambridge’s startup community, where founders support each other to build high-impact ventures.