MedEvidence! Truth Behind the Data

Dr. Michael Koren

Welcome to the MedEvidence! podcast, hosted by Dr. Michael Koren. MedEvidence, where we help you navigate the real truth behind medical research with both a clinical and research perspective. In this podcast, we will discuss with physicians with extensive experience in patient care and research. How do you know that something works? In medicine, we conduct clinical trials to see if things work! Now, let's get to the Truth Behind the Data. Contact us at www.MedEvidence.com

  1. 4d ago

    More Than the Winter Blues: The Science and Treatment of Depression

    Send us Fan Mail The winter months can bring more than colder weather and shorter days. For many people, this time of year can make depression symptoms harder to manage. But depression is much more than the winter blues, and the science behind it is more complex than a simple chemical imbalance. In this episode, Dr. Michael Koren talks with psychiatrist Dr. Heather Luing about the science of depression, how seasonal changes can affect mood, and when it's time to seek professional help. They explore lifestyle changes, psychotherapy, antidepressants, light therapy, transcranial magnetic stimulation (TMS), vagus nerve stimulation, ketamine, and emerging treatments being investigated through clinical research. They also discuss why traditional antidepressants don't work for everyone, how new treatment approaches are expanding options, and why there's reason for hope in the future of depression care. In this episode: - Why the holiday season and shorter days can be difficult for some people - What distinguishes major depressive disorder from everyday mood changes - How sleep, exercise, nutrition, and time in nature can support mental health - The limitations of the traditional serotonin-based approach to depression - How TMS, light therapy, and vagus nerve stimulation work - Emerging medications, ketamine, and psychedelic research - How clinical trials are helping advance depression treatment - When to seek help and how to support someone experiencing depression If you're struggling, help is available. Call or text 988 to connect with the Suicide & Crisis Lifeline for mental health or substance use support. Be a part of advancing science by participating in clinical research. Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.com Listen on Spotify Listen on Apple Podcasts Watch on YouTube Share with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released. Follow us on Social Media: Facebook Instagram X (Formerly Twitter) LinkedIn Want to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.com Music: Storyblocks - Corporate Inspired Thank you for listening!

    More Than the Winter Blues: The Science and Treatment of Depression

  2. Oct 28

    Standing Up And Taking the Lid of of POTS

    Send us Fan Mail Dr. Mitchell Rothstein joins Dr. Michael Koren to discuss Postural Orthostatic Tachycardia Syndrome, also called POTS. This condition, where heart rate rises when a person stands up, is often misunderstood and/or takes years to properly diagnose. The two doctors discuss the background and symptoms of POTS, but really dig deep into the broad problem of autonomic dysfunction. They distinguish between POTS and other autonomic problems, and look at how COVID and autoimmune diseases can cause autonomic dysfunction. Finally, the two doctors look at treatment options for POTS, including hydration, salt, medications, and new clinical trials. Be a part of advancing science by participating in clinical research. Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.com Listen on Spotify Listen on Apple Podcasts Watch on YouTube Share with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released. Follow us on Social Media: Facebook Instagram X (Formerly Twitter) LinkedIn Want to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.com Music: Storyblocks - Corporate Inspired Thank you for listening!

    Standing Up And Taking the Lid of of POTS

  3. Oct 21

    How to Lose Weight While Protecting Muscle

    Send us Fan Mail Weight loss can come with muscle loss, even when medication is involved. Dr. H. Jackson Downey shares practical guidance on strength training, protein intake, balanced meals, and smaller portions to help support muscle maintenance and make weight-loss treatment easier to manage. Be a part of advancing science by participating in clinical research. Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.com Listen on Spotify Listen on Apple Podcasts Watch on YouTube Share with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released. Follow us on Social Media: Facebook Instagram X (Formerly Twitter) LinkedIn Want to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.com Music: Storyblocks - Corporate Inspired Thank you for listening!

    How to Lose Weight While Protecting Muscle

  4. Oct 14

    Trust the Media for Medical News?

    Send us Fan Mail Medical headlines shape our food, our drugs, and our fears. But how much should we believe? In this episode, Dr. Michael Koren and Dr. Mitchell Rothstein explore how medical news is made, why headlines can be misleading, and how to tell the difference between evidence and hype. Learn a simple 4-step practical framework to evaluate health claims: check the claim, evidence, source, and incentives. We discuss study design, relative vs. absolute risk, and reporting on topics like Lp(a), daily aspirin, coconut oil, ivermectin, omega-3 supplements, and others. We also cover dietary supplements, FDA oversight, and marketing claims that may mislead consumers. Learn to read medical news with more confidence and make more informed health decisions. What health headline has you wondering what to believe? Be a part of advancing science by participating in clinical research. Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.com Listen on Spotify Listen on Apple Podcasts Watch on YouTube Share with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released. Follow us on Social Media: Facebook Instagram X (Formerly Twitter) LinkedIn Want to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.com Music: Storyblocks - Corporate Inspired Thank you for listening!

    Trust the Media for Medical News?

  5. Oct 7

    Gene Editing Moves from Science Fiction to Medical Miracle

    Send us Fan Mail Dr. Michael Hafran joins Dr. Michael Koren to discuss new investigational gene editing therapies. They talk about what genes and gene editing are, the history of gene editing, and some of the FDA-approved therapies on the market today. They also address fears people have about gene editing and clinical trials, explain the long and intensive safety measures in place, and reveal that these therapies aren't too different from what the body does naturally, just in a more guided and specific way to address genetic problems. They finish up by talking about an investigational medication designed to reduce an overactive cholesterol-related gene and lower the incidence of heart problems. Be a part of advancing science by participating in clinical research. Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.com Listen on Spotify Listen on Apple Podcasts Watch on YouTube Share with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released. Follow us on Social Media: Facebook Instagram X (Formerly Twitter) LinkedIn Want to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.com Music: Storyblocks - Corporate Inspired Thank you for listening!

    Gene Editing Moves from Science Fiction to Medical Miracle

  6. Sep 30

    Leading the Way in Clinical Research

    Send us Fan Mail Leslie Byatt joins Dr. Michael Koren to talk about leadership in the clinical research space. The two research professionals discuss the importance of qualified researchers in a research trial and the qualities that make for a good clinical research leader. They also talk about research as a treatment option and the benefits observed in research patients (even those in the placebo arm). They explain that the attention, care, and time with research professionals leads to better understanding and health for those who join, and that's on top of the altruistic benefits to science and health in general. Be a part of advancing science by participating in clinical research. Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.com Listen on Spotify Listen on Apple Podcasts Watch on YouTube Share with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released. Follow us on Social Media: Facebook Instagram X (Formerly Twitter) LinkedIn Want to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.com Music: Storyblocks - Corporate Inspired Thank you for listening!

    Leading the Way in Clinical Research

  7. Sep 23

    The Great Blood Pressure Showdown

    Send us Fan Mail A Cardiologist & Nephrologist Go Head-to-Head, er... "Heart-to-Kidney" Nephrologist Dr. Ali Rawabdeh joins Cardiologist Dr. Michael Koren to debate which is the bigger contributor (and problem) with high blood pressure: the heart or the kidneys. The two doctors discuss this extremely prevalent condition from their competing perspectives and give information on how different body systems can influence blood pressure. they also talk about the importance of understanding that blood pressure varies over time and that individual measurements are not the end-all of determining hypertension. They also dig into lifestyle and medical treatments for high blood pressure and upcoming genetic treatments that are currently being investigated. Be a part of advancing science by participating in clinical research. Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.com Listen on Spotify Listen on Apple Podcasts Watch on YouTube Share with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released. Follow us on Social Media: Facebook Instagram X (Formerly Twitter) LinkedIn Want to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.com Music: Storyblocks - Corporate Inspired Thank you for listening!

    The Great Blood Pressure Showdown

  8. Sep 16

    Pelacarsen Failed To Meet Its Primary Endpoint, But The Science Keeps Going

    Send us Fan Mail Cardiologists Dr. Seth Baum and Dr. Michael Koren discuss the newly released top-line results from a big Lp(a) study investigating the effects of the drug pelacarsen. They talk about what Lp(a) is, why it matters, happened in the study, and what this means for other pelacarsen and Lp(a) studies worldwide. They take a deep dive into some of the factors that can reduce the effectiveness of clinical trials and explain that this particular failure doesn't undermine the theory behind controlling Lp(a) levels or the potential effectiveness of competing investigational medications. Finally, the companion cardiologists talk about what this means for people who have high Lp(a) and what they can do to help control their risks of associated heart problems. Be a part of advancing science by participating in clinical research. Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.com Listen on Spotify Listen on Apple Podcasts Watch on YouTube Share with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released. Follow us on Social Media: Facebook Instagram X (Formerly Twitter) LinkedIn Want to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.com Music: Storyblocks - Corporate Inspired Thank you for listening!

    Pelacarsen Failed To Meet Its Primary Endpoint, But The Science Keeps Going
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Ratings & Reviews

5
out of 5
8 Ratings

About

Welcome to the MedEvidence! podcast, hosted by Dr. Michael Koren. MedEvidence, where we help you navigate the real truth behind medical research with both a clinical and research perspective. In this podcast, we will discuss with physicians with extensive experience in patient care and research. How do you know that something works? In medicine, we conduct clinical trials to see if things work! Now, let's get to the Truth Behind the Data. Contact us at www.MedEvidence.com

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