Grow Everything Biotech Podcast

Messaginglab
  • 4.9 (22)
  • Life Sciences
  • Updated Weekly

Grow Everything explores the world of biology as technology. Hosts Erum Khan and Karl Schmieder interview leaders and influencers biologizing industries with tools like synthetic biology, precision fermentation, bioprospecting, and more. These companies make biomaterials from waste, cosmetics that restore healthy hair and skin, and delicious cultivated foods in a bioreactor and so much more. Join us as we discuss the latest and greatest across biotech, engineered biology, entrepreneurship, and culture and how this transition is solving healthcare and climate change challenges.

  1. 6d ago

    194. Beauty Is in the AI of the Beholder: Debut’s Joshua Britton Turns Claims into Molecules

    Joshua Britton, founder and CEO of Debut, joins Erum Azeez Khan and Karl Schmieder to explain why the future of molecular creation belongs to AI and biotechnology. Joshua shares how watching biologists create complex natural molecules in days inspired his shift from traditional chemistry and shaped Debut’s vertically integrated model for discovering, manufacturing, formulating, and commercializing high performance beauty ingredients. The conversation explores why technical breakthroughs alone do not build durable biotech businesses, how consumer demand and measurable performance should guide discovery, and why formulation, supply chains, scientific communication, and brand education are essential to commercialization. Joshua also describes how Debut uses computational models to screen vast chemical spaces, validates promising candidates in the lab, balances fast internal innovation with longer corporate partnerships, and prepares brands for regulatory changes affecting familiar cosmetic ingredients. For founders, scientists, investors, and operators building the bioeconomy, this episode offers a practical playbook for turning biological innovation into products consumers understand, trust, and choose. Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing? Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters: (00:00:00) Biology, beauty, and the battle between performance and chemistry(00:07:00) Bio dyes, consumer perception, and why color changes experience(00:14:00) Joshua Britton’s path from organic chemistry to biotechnology(00:21:00) Why Debut chose vertical integration and consumer led discovery(00:28:00) Formulation failures that reshaped Debut’s commercial strategy(00:35:00) Balancing startup speed with global beauty partnerships(00:42:00) Regulatory pressure and the opportunity for new biological ingredients(00:49:00) Scientific communication, clinical proof, and brand adoption(00:56:00) What it takes to move biotechnology into the mass market(01:02:00) Key lessons on performance, AI, communication, and commercializationLinks and Resources: Debut BiotechDye vs No Dye Doritos Cheetos Taste Test on YoutubeDye vs No Dye Doritos Cheetos Taste Test on LinkedInNew imaginary color, "Olo"BioInnovations Events - For 25% off use code: Grow EverythingGrow Everything LinkedInTopics Covered: biotech beauty, synthetic biology beauty, AI ingredient discovery, biomanufacturing, vertically integrated biotech, beauty innovation, skincare ingredients, cosmetic formulation, consumer biotech, premium skincare Have a question or comment? Message us here: Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠ Music by: Nihilore  Production by: Amplafy Media

  2. Aug 7

    193. The Full Color Spectrum: Nick Milne Ferments One Pathway for Every Color at Octarine Bio

    Nick Milne, founder of Octarine Bio, joins Grow Everything to unpack how biology can reshape the future of color. In this episode, Nick explains why synthetic dyes have dominated textiles for more than a century, why sustainability alone is not enough to drive adoption, and how Octarine is building bio based pigments that can compete on performance, price, and scale. The conversation explores the environmental and human health problems tied to petrochemical dyes, especially azo dyes used in polyester, while showing how precision fermentation can create high strength pigments that work as drop in replacements for existing dye house workflows. Nick also shares how Octarine thinks about scale up, regulatory pressure in Europe, investor expectations, product development, and the practical realities of bringing biotech products into old and highly cost sensitive industries. Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing? Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters: (00:00:00) Nick previews Octarine’s high strength pigment platform(00:00:23) Karl and Erum open with science policy, AI, biosecurity, and discovery in nature(00:12:18) Introducing Nick Milne and Octarine Bio’s mission to rewrite color with biology(00:14:03) Why biology can outperform chemistry in rare but powerful commercial use cases(00:16:21) The slow shift from petrochemical dyes to bio based alternatives in textiles(00:18:31) What Pure Palette looks like as a drop in replacement for synthetic dyes(00:20:13) Octarine’s color pipeline, from purple and black to green, blue, red, and yellow(00:21:39) How stronger pigments create a path toward price parity for textile customers(00:28:13) Why European regulation may accelerate sustainable color adoption(00:31:15) Scale up, consistency, azo dyes, and lessons for biotech foundersLinks and Resources: Octarine BioOctarine Bio - PurePaletteNick Milne LinkedInOctarine Bio secures €5M to scale bio-based pigmentsGinkgo Bioworks and Octarine Bio Partnership Achieves Initial Success in Advancing Sustainable Dye ProductionScience, A New Golden AgeKristin Ellis’ Substack commentary on Science, A New Golden AgeNeuromancer Apple TV trailerA new species of Colobus monkey from the Lomami National Park, Democratic Republic of CongoBioInnovations Events - For 25% off use code: Grow EverythingGrow Everything LinkedInTopics Covered: Octarine Bio, bio-based pigments, synthetic dye replacement, sustainable textile dyes, fermentation-derived colors, metabolic engineering, azo dye alternatives, textile color sustainability, precision fermentation pigments, sustainable fashion materials Have a question or comment? Message us here: Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠ Music by: Nihilore  Production by: Amplafy Media

  3. Jul 31

    192. Reading Between the Dyes: Roya Aghighi Unlocks Biological Pigments at Lite-1

    Have you ever wondered why the color in your clothes can be so harmful to the environment? In this episode of the Grow Everything Podcast, Karl and Erum continue their BioDye series with Roya Aghighi, founder of Lite-1. Roya grew up in her mother’s fashion studio and later worked in the industry testing new materials, but she decided to leave after seeing the pollution caused by traditional dyeing methods. She explains how Lite-1 uses engineered microbes to produce colorful pigments through fermentation, beginning with black, one of the most difficult and damaging colors to make sustainably. Roya also discusses why natural variation in biology can be useful rather than a problem, and why the biggest challenge facing biological dyes may be getting brands and investors to share the risks of developing them. She predicts that color could eventually become an important tool for tracking a garment throughout its life. Before the interview, Karl and Erum also discuss radiation-loving microbes, cuts to pathogen testing, and organisms designed with the help of computers. Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing? Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters: (00:00:00) Biology as a technology and why textile dye is so harmful(00:05:00) Microbe expeditions, Bikini Atoll, and a Cyclospora outbreak(00:10:30) Cuts to pathogen monitoring and organisms designed with computers(00:16:40) Meet Roya Aghighi, from growing up in a fashion studio to founding a biotech company(00:22:45) How Lite-1 uses fermentation to create a more sustainable black dye(00:28:30) Why biological variation can be useful information(00:34:30) Focusing on performance, testing, and regeneration instead of sustainability alone(00:40:30) The challenges of cost, scale, and shared risk in the biological dye market(00:47:00) Product standards, traceability, and the next premium opportunity in fashion(00:52:00) Quick-fire questions and final thoughts from the hostsLinks and Resources: Lite-1 Bio Roya Aghighi177. Dye Another Day (REPLAY): The New Way to Color Textiles with Colorifix's Orr Yarkoni178. Pretty in Pigments: Jesse Adler Colors the Future with Pitri180. Fungi in Full Color: Ricky Cassini Reimagines Dye at Michroma181. Can Hue Believe It? Gerit Tolborg’s Quest for Pure Color at ChromologicsThe Next 500 years - Chris MasonBioAstraGrow Everything LinkedInBioInnovations Events - For 25% off use code: Grow EverythingTopics Covered: biological dyes, microbial color production, sustainable black dye, textile dye pollution, fermentation-based colorants, bio-based textile dyes, regenerative fashion, traceable garment dyes, synthetic dye alternatives, Lite-1 Bio Have a question or comment? Message us here: Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠ Music by: Nihilore  Production by: Amplafy Media

  4. Jul 24

    191. Beyond the Lab Bench: Karl & Erum on Human Connections as the Ultimate Biotech Moat

    With Episode 200 coming up, Karl and Erum switch roles and interview each other the way they usually interview their guests. Karl shares why he decided not to become a doctor, how interviewing bands in college taught him to connect with anyone, and what he learned about storytelling during a decade in public relations before starting Messaging Lab. Erum talks about her unexpected path from studying forensic chemistry and working in pharmaceutical labs to executive coaching, joining a startup accelerator on a ship traveling around the world, and working in energy policy from the Navajo Nation to Brussels. They also discuss what waiting tables taught them about sales and humility, why early-stage startups should sometimes stay quiet until they have real traction, and why strong relationships are something AI cannot replace. Along the way, they revisit favorite moments from past guests, including Vishaal Bhuyan, Casey Lardner, Glennis Mehra, Linnea Fletcher, Elizabeth Hénaff, Phil Morle, Michael Specter, and Sabriya Stukes. Their conversation is a reminder that there is no single path into the bioeconomy. Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing? Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters: (00:00:00) Karl and Erum interview each other ahead of Episode 200(00:06:45) Erum’s experience building a startup at sea with the Unreasonable Institute(00:13:30) Genspace’s Break Into Biotech program and lessons from college(00:19:58) Leaving the pharmaceutical lab for positive psychology and executive coaching(00:26:40) What working in restaurants teaches about sales, empathy, and humility(00:33:20) How energy and water policy work with the Navajo Nation shaped Erum’s perspective(00:40:02) Why staying quiet can be better than making a big launch announcement for an early-stage biotech company(00:46:31) Michael Specter discusses mistrust in science and the need for greater biology education(00:53:15) Career changes, layoffs, and staying adaptable in the age of AI(00:59:58) Advice for their younger selves and quick-fire questionsLinks and Resources: 45. Insuring Your Lunch: Aanika’s Vishaal Bhuyan Cracks the Microbial Code of Food Security139. Cultivating a Culture of Cultures? Genspace's Casey Lardner on Community Biotech30. Breaking into Biotech: Linnea Fletcher's Inclusive Education and Workforce Upskilling at InnovATEBIO117. From Lab Coats to CEO Notes: BioLabs' Glennis Mehra on Biotech Business in NYC104. Unseen Worlds: Exploring Environmental Microbiomes and Their Secrets of Human and Climate Impact with Dr. Elizabeth Henaff149. Beyond Capital: Phil Morle of Main Sequence Ventures on Collaboration as the New Competitive Edge44. Spec-Tacular Science: A Chat with Michael Specter on Denying Denialism39. From Microbe to Unicorn: IndieBio's Sabriya Stukes on the Journey of Biotech StartupsAI Value PyramidGrow Everything LinkedInBioInnovations Events - For 25% off use code: Grow EverythingTopics Covered: community biotech, biotech storytelling, biotech founders, biotech communications, life lessons in biotech, biotech careers, science entrepreneurship, biotech media, biotech community building, biotech journey Have a question or comment? Message us here: Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠ Music by: Nihilore  Production by: Amplafy Media

  5. Jul 17

    190. Pour Some Sugar on Yeast: Lisa Roessler Scales Biology at Amyris

    Lisa Ressler has spent more than 35 years working in science-based businesses, including DuPont and Evonik, and now serves as Chief Commercial Officer at Amyris. In this conversation, she joins Karl and Erum to discuss where Amyris stands today, what the company learned from Chapter 11, and why returning its focus to B2B science was the right move. Lisa explains the company’s 1.5 million-liter fermentation facility in Barra Bonita, Brazil, its partnership with Wacker to develop bio-based personal care ingredients, and the simple framework she uses to decide which markets are worth pursuing. She also shares what it takes for a bio-based ingredient to move beyond higher “green” pricing and reach large-scale commercial use, making the case that strong performance is ultimately what convinces customers. Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing? Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters: (00:00:00) - Introduction and catching up after the Fourth of July(00:05:00) - Soil health, regenerative agriculture, and current biotech trends(00:10:00) - Biomanufacturing in China and the global race for scale and speed(00:15:00) - Meet Lisa Ressler, Chief Commercial Officer at Amyris(00:19:00) - What Amyris produces and how it works with partners across the supply chain(00:24:00) - Amyris’s return to B2B and what enterprise customers want after Chapter 11(00:31:00) - How Amyris and Wacker collaborate from research through development(00:37:00) - Proprietary molecules and how Amyris chooses which markets to pursue(00:41:00) - Exploring Amyris’s molecule portfolio, from squalane to vaccines(00:48:00) - The future of precision fermentation and quick-fire questionsLinks and Resources: AmyrisLisa RoesslerAmyris' sustainable squaleneAmyris, Inc. Launches New Production Line at Brazil Precision Fermentation PlantWACKER and biomanufacturing pioneer Amyris join forces in the personal-care sector179. D.C. Climate Week LIVE: The Road to Remake Everything183. The American Biotech Blueprint: Senator Todd Young on Biodiversity as National Security73. At the Bleeding Edge: Cresilon's Joe Landolina on Rapid Wound Care141. Gut Check! Viome’s Momo & Guru Decode Your Inner Microbiome158. Mycelium On, Sound Off: How GOB's Lauryn Menard Makes Biomaterials Feel Like CultureSilvaBio and Foray Bioscience Announce Acceleration to Restore the American ChestnutCommon Ground - agriculture documentarySiphonophore - longest animalBioInnovations Events - For 25% off use code: Grow EverythingTopics Covered: precision fermentation, Amyris, squalane, sustainable beauty ingredients, bio-based chemistry, PFAS alternatives, industrial biotechnology, synthetic biology, vaccine adjuvant squalene, green chemistry Have a question or comment? Message us here: Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠ Music by: Nihilore  Production by: Amplafy Media

  6. Jul 10

    189. Infinite Threads: Recycling Athleisure Waste with Samsara’s Vanessa Vongsouthi

    Vanessa Vongsouthi, Research Founder and Head of Bioengineering at Samsara Eco, joins host Erum on the Grow Everything Podcast to discuss how engineered enzymes and AI are making it possible to recycle textiles and plastics repeatedly. Vanessa explains how Samsara uses AI-assisted protein design and ancestral sequence reconstruction to create enzymes that break down complex polymers, including Nylon 6,6, into their original chemical building blocks. Those materials can then be returned to existing supply chains and used to create virgin-equivalent products that are indistinguishable from materials made from petrochemicals. She also shares the story behind the world’s first enzymatically recycled Nylon 6,6 jacket, created in partnership with Lululemon, and explores how Samsara Eco was built through Main Sequence Ventures’ orchestration model alongside partners such as Woolworths and the Australian National University. The conversation also looks at what a future built around distributed, local recycling infrastructure could mean for designers, manufacturers, consumers, and the global circular economy. Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and innovators changing the world through biology. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing? Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters: (00:00:00) - Intro: Heat waves, climate impacts, and the bioeconomy(00:03:00) - Would Big Tech buy a pharmaceutical company?(00:08:00) - Brewed human collagen: Gelatech x Hugel partnership(00:10:00) - France bans fast fashion: Shein, Temu, and the Atacama Desert(00:13:00) - Introducing Vanessa Vongsouthi of Samsara Eco(00:17:00) - Biology as future industrial infrastructure(00:22:00) - Programming enzymes with AI and ancestral sequence reconstruction(00:29:00) - The Lululemon jacket: proof that enzymatic recycling scales(00:35:00) - Distributed recycling and a circular material economy(00:42:00) - Post-interview debrief and key takeawaysLinks and Resources: Forbes - Vanessa VongsouthiSamsara EcoSamsara Eco - LinkedInHow Samsara Eco made a jacket with Lululemon from enzymatically recycled polyesterlululemon and Samsara Eco Announce 10-Year Plan to Advance Recycled Material PortfolioThe world has an anchovy problemAI Age Anthropic launches AI drug discovery program, joining tech giants in betting on healthcareFDA to fast-track food as medicineJellatech Partners with South Korea’s Hugel to Bring Cell-Cultured Human Collagen to MarketFrench parliament passes fast fashion bill targeting Shein and Temu149. Beyond Capital: Phil Morle of Main Sequence Ventures on Collaboration as the New Competitive Edge45. Insuring Your Lunch: Aanika’s Vishaal Bhuyan Cracks the Microbial Code of Food Security122. Ecohacking the Planet: Daniel Goodwin of Homeworld Collective Brews Up Planetary-Scale Solutions175. Seaweed Is the New Oil: Mari Granström Builds Origin by OceanGrow Everything LinkedInBioInnovations Events - For 25% off use code: Grow EverythingTopics Covered: enzymatic recycling, nylon 66 recycling, textile waste, circular economy, bioengineering, protein engineering, infinite recycling, sustainable fashion, Lululemon recycled jacket, plastic recycling technology Have a question or comment? Message us here: Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠ Music by: Nihilore  Production by: Amplafy Media

  7. Jul 3

    188. Which Came First: Chicken, Egg, or Medicine? Neion Bio Turns Evolution into a Precision Factory

    What happens when an evolutionary biologist and an aerospace engineer both arrive at the same conclusion — that the future of drug manufacturing isn't steel, it's biology? In this episode, Karl Schmieder and Erum Azeez Khan sit down with Sam Levin (Co-Founder & CTO) and Dimi Kellari (Co-Founder & CEO) of Neion Bio to unpack one of the most counterintuitive ideas in modern biomanufacturing: producing therapeutic medicines inside genetically engineered chicken eggs. Rather than optimizing the same mammalian cell culture systems that have defined biopharma for 50 years, Neion Bio's Raptor platform replaces complex steel bioreactor infrastructure with a self-replicating, two-input biological system — chicken feed and water in, life-saving medicines out. The conversation covers their stealth-to-commercial journey, a multi-product monoclonal antibody partnership announced alongside $11M in seed funding, the scalability and supply chain resilience advantages of egg-based manufacturing, how they navigate FDA regulation with a living bioreactor, and their North Star: dropping end-to-end production costs of monoclonal antibodies below $10 per gram — an order of magnitude that could fundamentally reshape who has access to biologics and where they're made. Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing? Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters: (00:00:00) - Intro & 4th of July: America's 250th anniversary celebrations(00:03:00) - America's Living Library Act & NDAA biotech provisions(00:06:00) - Midjourney's ultrasonic body scanner & patient data ownership(00:10:00) - NVIDIA's AI co-scientist, the AI value pyramid & AbbVie's $11B Apogee acquisition(00:20:00) - Introducing Sam Levin & Dimi Kellari of Neion Bio(00:26:00) - Neion Bio's Raptor platform: making medicines inside chicken eggs(00:33:00) - Scalability, onshoring & true supply chain resilience(00:39:00) - Downstream purification: cracking eggs vs. CHO cell lysate(00:47:00) - FDA pathways & batch-to-batch consistency in a living bioreactor(00:50:00) - Drug supply chain fragility & national health security(00:56:00) - $10/gram North Star: end-to-end cost breakdown(01:00:00) - Quickfire Q&A: engineering challenges, union demands & investor misconceptions(01:04:00) - Outro: calls to action & what's next for Neion BioLinks and Resources: Neion BioContact to partner with Neion BioChicken Eggs Become BiorectorsNeion Bio Raises Oversubscribed $23 Million Series A to Advance Biologics Manufacturing Platform and Expand Pipeline183. The American Biotech Blueprint: Senator Todd Young on Biodiversity as National Security186. N.Y. Tech Week Live Demo: Engineering the Future of Manufacturing with Roebling's Brentan Alexander170. There's a Bug for That: Sophia Xu on CarbonBridge's Notebook Bioreactors176. Dare to Commercialize: Damien Perriman’s eXoZymes PlaybookNVIDIA announces BioNeMoA.I. Value Pyramid - Murat AktihanogluAbbVie to acquire Apogee for $11BGrow everything LinkedInBioInnovations Events - For 25% off use code: Grow EverythingTopics Covered: chickens, eggs, biomanufacturing, therapeutic medicines, CHO cells, monoclonal antibodies, supply chain, biosimilars, Raptor, national health security Have a question or comment? Message us here: Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠ Music by: Nihilore  Production by: Amplafy Media

  8. Jun 26

    187. One Small Step for a Microbe: Lynn Rothschild’s Leap from Astrobiology to Bioengineering at NASA

    What does it actually take to keep humans alive on Mars? Not the SpaceX version — the biology version. Dr. Lynn Rothschild, research scientist at NASA Ames and adjunct professor at Brown and Stanford, has spent decades at the intersection of astrobiology and synthetic biology, and her answer is both elegant and radical: life itself is the technology. On this episode, Karl and Erum sit down with one of the scientists who helped build NASA's synthetic biology program to talk about on-demand drug manufacturing in space, growing habitats out of fungal mycelium, engineering bacteria to pull specific metals from e-waste, and the audacious "Hell Cell" project that aims to stack every survival superpower nature has ever evolved into a single organism. If you've ever wondered what it looks like when evolutionary biology meets aerospace engineering meets materials science — with a healthy dose of iGEM undergrads and Tetris metaphors — this one's for you. Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing? Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters: (00:00:00) - NYC energy, the Knicks parade, and when does biotech get its ticker tape?(00:04:00) - Peptides: biohacking goes mainstream, and why the back alley of your gym is not a pharmacy(00:10:00) - Bemotrizinol: the first new active sunscreen ingredient cleared in the US in over 20 years(00:14:30) - Listener shoutouts and a night with sci-fi legend Kim Stanley Robinson at Pioneer Works(00:22:30) - SpaceX goes public at a $2.5 trillion valuation — what the space economy actually means(00:26:00) - Why biology — not steel or solar — is the only real answer to the upmass problem(00:35:00) - Lynn's origin story: from studying extremophiles to being told to engineer them for NASA(00:42:00) - The astro pharmacy: programming bacteria to brew medicine on demand during a six-month Mars transit(00:51:00) - The Hell Cell, AI in the lab, and Lynn's Tetris approach to building multi-disciplinary teams(01:04:00) - Gravity, radiation, the 2030s Mars timeline, and what from Lynn's lab shows up in your house firstLinks and Resources: Lynn RothschildNASA interview with Lynn RothschildNature's Hardware Store - Lynn on Building the Future with BiologyThe Peptide Gold RushBemotrizinol - new FDA approved sunscreen ingredient185. Brick Happens: Chris Maurer of Redhouse Studio Redesigns Remote Living for Earth and Mars93. Houston, We Have a Protocol: NASA's Kate Rubins on Biotech in Space116. Cell Yeah for Space!: Pioneer Labs' Erika DeBenedictis on Engineering Life for Mars156. When Matter Makes Decisions: Michael Levin on the Intelligence of Form111. Space Genes and Subway Scenes: Chris Mason on Planning Life’s Next Big LeapBioInnovations Events - For 25% off use code: Grow EverythingTopics Covered: Synthetic biology in space, astrobiology, space biomanufacturing, Mars missions, biomining, on-demand pharmaceuticals, extremophiles, mycelium architecture, space sustainability, lunar infrastructure Have a question or comment? Message us here: Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠ Music by: Nihilore  Production by: Amplafy Media

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About

Grow Everything explores the world of biology as technology. Hosts Erum Khan and Karl Schmieder interview leaders and influencers biologizing industries with tools like synthetic biology, precision fermentation, bioprospecting, and more. These companies make biomaterials from waste, cosmetics that restore healthy hair and skin, and delicious cultivated foods in a bioreactor and so much more. Join us as we discuss the latest and greatest across biotech, engineered biology, entrepreneurship, and culture and how this transition is solving healthcare and climate change challenges.

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