Journal of Neurophysiology

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Podcasts created by the Journal of Neurophysiology community

  1. 10/29/2025

    Deep brain stimulation of A13 region evokes robust locomotory response in rats

    In this episode, coauthors Anupam Bisht and Cecilia Badenhorst discuss their study, “Deep brain stimulation of A13 region evokes robust locomotory response in rats.” Their research demonstrates that deep brain stimulation (DBS) of the A13 region in rats robustly increases locomotor activity without inducing anxiety using a novel wireless stimulation approach, suggesting that A13 may be a promising therapeutic target for gait dysfunction in Parkinson’s disease.    Deep brain stimulation of A13 region evokes robust locomotory response in rats Anupam Bisht, Cecilia Badenhorst, Zelma H. T. Kiss, Kartikeya Murari, and Patrick J. Whelan Journal of Neurophysiology 2025 133:5, 1594-1606

    14 min

  2. 10/03/2025

    Pharmacological modulation of the M-current shapes locomotor function in developing zebrafish

    In this episode, coauthors Stephanie Gaudreau and Tuan Bui discuss their recently published research, “Pharmacological modulation of the M-current shapes locomotor function in developing zebrafish.” For the first time, they show that the M-current influences escape responses and swimming in larval zebrafish, with experiments in isolated spinal preparations revealing its presence in spinal circuits. Pharmacological modulation of the M-current shapes locomotor function in developing zebrafish Stephanie F. Gaudreau and Tuan V. Bui Journal of Neurophysiology 2025 133:6, 1795-1806

    9 min

  3. 09/12/2025

    Legacy of Dr. Joseph Erlanger: A Conversation with Dorothy Erlanger and Dr. Nino Ramirez

    In our latest episode, Journal of Neurophysiology Editor-in-Chief Dr. Nino Ramirez discusses the life and scientific legacy of Dr. Joseph Erlanger with Dr. Erlanger’s granddaughter, Dorothy Erlanger. While the world knows Dr. Joseph Erlanger as a scientific pioneer in the fields of neuroscience and cardiovascular science, Dorothy Erlanger remembers her grandfather as a humble person who enjoyed weekly dinners and playing cards with his family. His work as an experimental pioneer led Dr. Erlanger, along with his collaborator Dr. Herbert Gasser, to be the first to visualize an action potential with the cathode-ray oscilloscope. This discovery led to Dr. Erlanger being awarded the Nobel Prize and continues to drive scientific discovery to this day. Listen as Dorothy Erlanger shares anecdotes about her grandfather’s real life as a scientist with engaging personal details, such as the description of the challenges Dr. Erlanger faced trying to obtain clean electrophysiological tracings with a streetcar line running beside the laboratory building. Dr. Ramirez shares the fascinating history of why Dr. Erlanger’s work was so revolutionary. How did Dr. Erlanger’s discovery about the complexities of differently shaped action potentials lead to breakthroughs in anesthesia, analgesia, and our understanding of pain? Listen now and find out.   Erlanger Family Gifts Renowned Physiologist’s Nobel Medal to APS

    34 min

  4. 09/03/2025

    Higher hyperpolarization activated current (Ih) in a subpopulation of interneurons in stratum oriens of area CA1 in the hippocampus of Fragile X mice

    In this episode, coauthor Lauren Hewitt discusses her recently published study, “Higher hyperpolarization activated current (Ih) in a subpopulation of interneurons in stratum oriens of area CA1 in the hippocampus of Fragile X mice.” The research examines how inhibitory interneurons are altered in a fragile X mouse model, revealing that increased Ih current reduces the excitability of a specific interneuron subtype. These findings highlight how changes in voltage-gated ion channel function can disrupt the brain’s excitatory/inhibitory balance, offering new insights into circuit dysfunction in fragile X syndrome.   Higher hyperpolarization-activated current in a subpopulation of interneurons in stratum oriens of area CA1 in the hippocampus of fragile X mice   Lauren T. Hewitt, Alyssa M. Marron, and Darrin H. Brager Journal of Neurophysiology 2025 133:5, 1558-1571

    6 min

  5. 08/22/2025

    Emerging evidence on the effects of electrode arrangements and other parameters on the application of transcutaneous spinal direct current stimulation

    In this episode of the Journal of Neurophysiology’s podcast series, coauthor Andrea Gigliotti discusses the newly published review, “Emerging evidence on the effects of electrode arrangements and other parameters on the application of transcutaneous spinal direct current stimulation.” Gigliotti explains how computer simulations are helping researchers understand the role of electrode placement, polarity, and tissue properties in shaping tsDCS outcomes. He also describes why dosage may matter less than previously thought and what future trials should consider to make tsDCS more effective in both research and clinical settings.   Emerging evidence on the effects of electrode arrangements and other parameters on the application of transcutaneous spinal direct current stimulation Andrea Gigliotti and Hugo M. Pereira Journal of Neurophysiology 2025 133:2, 709-721

    5 min

  6. 07/29/2025

    Motor Unit Firing Rates During Arm Cycling vs. Isometric Contractions

    In this episode, coauthor Daniel C. Basile discusses the team’s newly published research, "Investigating motor unit firing rates during arm cycling compared with intensity-matched isometric contractions in humans." Until now, motor unit firing rates (MUFRs) during upper-limb locomotor tasks had not been recorded in humans, leaving gaps in our understanding of how motor units behave during dynamic, CPG-mediated activity. Using indwelling fine-wire electrodes, the study reveals that MUFRs are significantly higher during arm cycling compared to isometric contractions, pointing to distinct neural control strategies between these movement types. Tune in to explore the implications for motor control and rehabilitation science.   Investigating motor unit firing rates during arm cycling compared with intensity-matched isometric contractions in humans Daniel C. Basile, Alysha D. Wira, Charles L. Rice, and Kevin E. Power Journal of Neurophysiology 2025 134:1, 162-170

    8 min

  7. 07/29/2025

    Alpha Rhythms and Occluded Motion in Natural Scenes

    In this episode, coauthors Lu-Chun Yeh and Daniel Kaiser discuss their recently published Short Report, "Cortical alpha rhythms interpolate occluded motion from natural scene context." When objects or people become temporarily hidden from view, our brains rely on environmental cues to predict their motion. This study shows that cortical alpha oscillations play a key role in this process, tracking not only visible movement but also anticipating whether motion continues or stops based on obstacles in the scene. Tune in to learn how these brain rhythms help us fill in the blanks of dynamic, real-world perception.   Cortical alpha rhythms interpolate occluded motion from natural scene context Lu-Chun Yeh, Max Bardelang, and Daniel Kaiser Journal of Neurophysiology 2025 133:5, 1497-1502

    5 min

  8. 07/29/2025

    Uncovering Perceptual Templates with Natural Statistics

    In this episode of the Journal of Neurophysiology’s podcast series, coauthor Lorenzo Landolfi joins us to discuss the newly published research titled "Reverse correlation of natural statistics for ecologically relevant characterization of human perceptual templates." Reverse correlation remains a cornerstone technique for probing neuronal and perceptual receptive fields, yet its application to naturalistic behavior is complicated by the complex structure of real-world stimuli. While advances in accounting for natural statistics have shown promise in neuronal studies, their relevance to human perception has remained uncertain—until now. Landolfi explains how these methods can be extended to psychophysical settings, the important caveats researchers must consider, and what the findings reveal about how we interpret our visual world.   Reverse correlation of natural statistics for ecologically relevant characterization of human perceptual templates Lorenzo Landolfi and Peter Neri Journal of Neurophysiology 2025 133:6, 1717-1739

    6 min
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Podcasts created by the Journal of Neurophysiology community

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  • Creator
    jneurophysiol
  • Years Active
    2023 - 2025
  • Episodes
    100
  • Rating
    Clean
  • Copyright
    © Copyright 2026 American Physiological Society
  • Show Website
    Journal of Neurophysiology