Good Science Good Life

Matt Fuchs

Good Science Good Life features interviews with leading scientific experts on research-backed approaches to cultivating the good life. Learn about the latest, most credible research on developing a sense of purpose, performing at your peak, having great health and longevity, fulfilling your potential and just becoming happier and more satisfied. The podcast is hosted by journalist Matt Fuchs.

Episodes

  1. 05/04/2025

    The World's Longest Running Study on Happiness, with Dr. Bob Waldinger

    What makes for a good life? Such a simple question, yet we don't have great answers. Most of us try to figure it out as we go along, and many end up feeling like they never got to the bottom of it. Shouldn't something so important be approached with more scientific rigor? In 1938, Harvard researchers began a study to fill this gap. Since then, they’ve followed hundreds of people over the course of their lives, hoping to identify which factors are key to long-term satisfaction. Eighty-five years later, the Harvard Study of Adult Development is still going. And today, its directors, the psychiatrists Bob Waldinger and Marc Shulz, have published a book that pulls together the study’s most important findings. It’s called The Good Life: Lessons from the World’s Longest Scientific Study of Happiness. In this podcast episode, I talked with Dr. Waldinger about life lessons that we can mine from the Harvard study and his new book. Dr. Waldinger is Clinical Professor of Psychiatry at Harvard Medical School, in addition to being Director of the Harvard Study of Adult Development. He got his M.D. from Harvard Medical School and has published numerous scientific papers he’s a practicing psychiatrist and psychoanalyst, he teaches Harvard medical students, and since that is clearly not enough to keep him busy, he’s also a Zen priest. His book is a must-read if you’re looking for scientific evidence on how to design your life for more satisfaction so someday in the future you can look back on it without regret, and this episode was an amazing conversation in which Dr. Waldinger breaks down many of the cliches about the good life… making his advice real and tangible. We also get into what he calls “side-by-side” relationships, personality traits for the good life, and the downsides of being too strict about work-life balance. Show links - Bob Waldinger - Waldinger's book, The Good Life: Lessons from the World's Longest Scientific Study of Happiness - The Harvard Study of Adult Development - Waldinger's Ted Talk - Gallup report finding that people with good friends at work have higher engagement with their jobs - The link between relationships and well-being - Those with social connections live longer This episode features a discussion originally recorded for MSoS.

    57 min
  2. 05/04/2025

    Cutting Calories Could Slow Down Aging, According to New Research

    Last Thursday, scientists at Columbia University published a new study finding that cutting down on calories could lead to longer lives. In the phase 2 trial, 220 healthy people without obesity dropped their calories significantly, and a test of their biological age showed that their rate of aging slowed by 2 to 3 percent in over a couple of years. Small though that may seem, it amounts to a decline of about 10 percent in the risk of death as people get older, according to the researchers' estimate. That's basically the same as quitting smoking. Previous research has shown that restricting calories results in longer lives for mice, worms and flies. This research is unique because it applies those findings to people. It was published in Nature Aging. But what did the researchers actually show? Does the new paper point to anything people should be doing to have longer, healthier lives? Spoiler alert: Maybe, but first, you'd want to consult a medical expert about it. I had the chance to chat with someone with inside knowledge of the research -- Dr. Evan Hadley, director of the National Institute of Aging's Division of Geriatrics and Clinical Gerontology, which funded the study. Dr. Hadley describes how the research participants went about reducing their calories, as well as the risks and benefits involved. He also explains the "aging clocks" used to measure the benefits. This episode features a discussion originally recorded for MSoS.

    11 min
  3. 02/24/2025

    How to Use Thoughts to Control Computers with Dr. Tom Oxley

    Tom Oxley is building what he calls a “natural highway into the brain” that lets people use their minds to control their phones and their computers. The device, called the Stentrode, could improve the lives of hundreds of thousands of people living with spinal cord paralysis, ALS and other neuro degenerative diseases. Leaps.org talked with Dr. Oxley for today’s podcast. A fascinating thing about the Stentrode is that it works very differently from other “brain computer interfaces” you may be familiar with, like Elon Musk’s Neuralink. Surgeons implant the some BCIs directly into a person’s brain, but the Stentrode is much less invasive. Dr. Oxley’s company Synchron opts for an ingenious “natural” approach, using stents in blood vessels to access the brain, with some major advantages for a handful of people who’ve already started using the Stentrode.  The audio improves about 10 minutes in. There was a minor headset issue early on but everything is audible throughout.  In our conversation, Dr. Oxley talks about what it means to have a “Bluetooth brain,” the critical role played by AI in the present and future of BCIs, how BCIs compare to voice command technology, regulatory frameworks for revolutionary technologies, specific people with paralysis who’ve been able to regain some of their independence thanks to the Stentrode, what it means to be a neurointerventionist, how to scale BCIs so that more people can use them, the risks of BCIs malfunctioning, organic implants, and how BCIs help us understand the brain, among other topics.  Dr. Oxley received his PhD in neuro engineering from the University of Melbourne in Australia. He is the founding CEO of Synchron and an associate professor and head of the vascular bionics laboratory at the University of Melbourne. He’s also a clinical instructor in the Deepartment of Neurosurgery at Mount Sinai Hospital. He’s completed more than 1,600 endovascular neurosurgical procedures on patients, including those with aneurysms and strokes, and has authored over 100 peer reviewed articles.  Dr. Oxley’s work opens up game-changing opportunities for many patients, and his views on the present and future of BCIs are must listening for anyone who cares about health and technology.   Links: Synchron - https://synchron.com/  Tom Oxley social links https://www.linkedin.com/in/tomoxl https://twitter.com/tomoxl?lang=en  Tom Oxley TED talk and website  https://www.ted.com/talks/tom_oxley_a_brain_implant_that_turns_your_thoughts_into_text?language=en https://tomoxl.com/  Novel brain implant helps paralyzed woman speak using digital avatar - https://engineering.berkeley.edu/news/2023/08/novel-brain-implant-helps-paralyzed-woman-speak-using-a-digital-avatar/  Edward Chang lab - https://changlab.ucsf.edu/  BCIs convert brain activity into text at 62 words per minute - https://med.stanford.edu/neurosurgery/news/2023/henderson-brain-implant-speech-als This episode features a discussion originally recorded while I was hosting MSoS.

    39 min

About

Good Science Good Life features interviews with leading scientific experts on research-backed approaches to cultivating the good life. Learn about the latest, most credible research on developing a sense of purpose, performing at your peak, having great health and longevity, fulfilling your potential and just becoming happier and more satisfied. The podcast is hosted by journalist Matt Fuchs.