Rational Optimization \w Elias Schlie

Elias Schlie
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Hi, I'm Elias. 👋 I love progress and feel joy when my knowledge and capabilities expand. I want to understand the mysteries of reality, travel the stars, and enhance my cognitive and physical abilities to levels that we can't even imagine right now. AI is likely the biggest existential risk that humanity currently faces, so I decided to dedicate myself to making it safer. Currently, I'm finishing my Cognitive Science and Artificial Intelligence Bachelor's (1 year faster & Summa Cum Laude) and am starting to do my own research on the side.

  1. 08/07/2025

    Personal diary - July 2025

    This month, I built AI agents, I moved, I fasted, and I hiked. In this podcast, I share the stories that I experienced and the insights I found. YouTube version My website: eliasschlie.com Quick Stats 📊⏱️ Total focused work: 288 hours and 46 minutes🗓️ That’s an average of 9 hours and 57 minutes every single day — weekends included!💾 Full breakdown publicly available here: eliasschlie.com What I spent my time on 🧠 🚀 Deep dive into AI agents and language model tooling (esp. langchain + agents) 🧪 Built a custom MCP server to connect LLMs with Obsidian for persistent memory scaffolding 🧭 Personal reflection on direction, meaning, and intrinsic values (inspired by valuism) 💬 Developing systems for better conversations and group dynamics 📚 Listening to high-signal content during breaks to stay immersed in key problems Main Achievements 🏆 ✅ Built and shipped my own MCP server — clean, simple, and powerful ✅ Reached a new level of clarity on what I value and why it matters ✅ Used fasting as a powerful tool to reset and return to deep focus ✅ Refined my approach to learning through better break design and structured reflection ✅ Pushed physical + mental boundaries with a 50h fast + night hike — reminder of agency over mind and body

    50 min

  2. 07/07/2025

    Personal Diary - Jun 2025

    **June 2025: The Month I Started Building** Quick Stats 📊 ⏱️ Total focused work: \~300 hours 🗓️ That’s 9 hours and 49 minutes every day (including weekends) 💾 Full work log published at [https://github.com/EliasSchlie/Working\_Hours](https://github.com/EliasSchlie/Working_Hours) What I spent my time on ⚡ * Finished exams for 9 university courses in Cognitive Science & AI (across three different semesters) * Deep work on AI agents, automation, and building new tools * Built foundational scripts for automating my note-taking (Obsidian) with LLMs and tools * Explored and prototyped AI agents for science (especially agents to automate news & paper summarization) * Researched and learned more about AI agent architectures and how to use tools/APIs for automation * Started serious learning in JavaScript/TypeScript and web development (CS50 Web, JavaScript fundamentals course) * Continued refining systems for both learning and building Main Achievements 🏆 ✅ Completed 9 courses in about a month, with top or near-top grades in multiple cohorts ✅ Built the first versions of AI agents to automate my note-taking and science workflows ✅ Prototyped a system to automatically create and publish longevity science podcast episodes from new research papers ✅ Developed and used structured note-taking, now over 10,000 notes (“second brain”) ✅ Shifted from pure learning mode to building mode, exploring new personal systems for productivity ✅ Stayed consistent with high work hours, while keeping balance with gym, sauna, and friends ✅ Maintained strong intrinsic motivation—doing exactly what I’d do even if given €1 million ⁠YouTube⁠ version

    26 min

  3. 06/15/2025

    Google's new AI makes scientific discoveries: AlphaEvolve (DeepMind) & Implications for Longevity Science

    eliasschlie.com

    15 min

  4. 06/15/2025

    Personal Diary — May 2025

    eliasschlie.com

    12 min

  5. 05/20/2025

    Longevity News - May 2025

    My website 🐭 FDA Plans to Replace Animal Testing — A Roadmap to Reducing Animal Testing in Preclinical Safety Studies 🤖 Why Didn't AI Discover a Bunch of Drugs Yet? — Progress, Pitfalls, and Impact of AI-driven Clinical Trials (Wilczok & Zhavoronkov, 2025) ⏰ LinAge2 – Aging Clock Update — Providing actionable insights and benchmarking with epigenetic clocks (Fong et al., 2025) 🚀 Frontier Tower — Permanent Longevity Hub in San Francisco 🏝️ Vitalist Bay — Giant Longevity Pop-Up City

    1h 1m

  6. 05/09/2025

    Personal Diary - April 2025

    My website

    19 min

  7. 05/06/2025

    Longevity News - April 2025

    1) 🐁 The Rodent Aging Interventions Database (RAID) 2) 🧫 High-Throughput Yeast Aging Study 3) 🤖 Metabolic Digital Twins 4) 🏙️ How Cities Can Be Used to Learn About Aging and Exposome Influences 5) 🐷 First-ever pig-human liver transplant

    1h 19m

  8. 04/05/2025

    Machine Learning March

    ⁠⁠My Website

    34 min
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About

Hi, I'm Elias. 👋 I love progress and feel joy when my knowledge and capabilities expand. I want to understand the mysteries of reality, travel the stars, and enhance my cognitive and physical abilities to levels that we can't even imagine right now. AI is likely the biggest existential risk that humanity currently faces, so I decided to dedicate myself to making it safer. Currently, I'm finishing my Cognitive Science and Artificial Intelligence Bachelor's (1 year faster & Summa Cum Laude) and am starting to do my own research on the side.

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