The Daily Apple Podcast

Prime Health Associates - Kevin White, MD

We dive into all topics regarding the science of longevity along with some other subjects we find of interest with the hopes to provide useful information for everyone. This stems from our personal interest to optimize the human condition to not just live longer, but live better.

  1. 1d ago

    Can Rapamycin Reverse Brain Aging? Dr. Veronica Galvan on the Alzheimer's Research Surprising Even Her

    Send us Fan Mail In this episode, Dr. Kevin White sits down with Dr. Veronica Galvan, Presidential Professor at the University of Oklahoma Health Sciences Center and Director of the Oklahoma Nathan Shock Center on Aging. Most people think Alzheimer's is caused by a buildup of "bad" proteins in the brain. The real story is more complicated, and more hopeful. Galvan has spent her career studying what actually drives Alzheimer's disease, and her research has uncovered something surprising: a common, decades-old drug may be able to reverse brain damage that was thought to be permanent. Together they explore: What's really happening in the brain during Alzheimer's, and why the "bad protein" explanation is incompleteWhy aging itself, not genetics, is the single biggest risk factor for Alzheimer's diseaseWhat your APOE gene type (2, 3, or 4) actually means for your riskHow rapamycin, a drug originally used for organ transplants, reversed brain damage in animal studies"It wasn't improving. It was restoring." — Dr. Veronica GalvanWhy some people's brains show significant Alzheimer's damage on scans but never lose their memory or functionThe simplest, most overlooked factor that can change your brain's trajectory as you ageAlong the way, Galvan shares what pulled her from virology into Alzheimer's research, why she believes large-scale human trials on rapamycin are long overdue, and what she'd study next if funding were no object. Whether you have a family history of dementia, want to understand the research behind the headlines, or are simply thinking ahead about how to protect your brain, this episode offers a clearer picture of where the science actually stands. Guest  Dr. Veronica Galvan  Presidential Professor, University of Oklahoma Health Sciences Center  Director, Oklahoma Nathan Shock Center on Aging Follow The Daily Apple for weekly conversations on longevity, performance, prevention, nutrition, exercise, and the science of living well. If you enjoyed this episode, please subscribe, leave a review, and share it with someone who's committed to living a longer, healthier life. www.primehealthassociates.com Instagram: @KevinWhiteMD YouTube: @KevinWhiteMD Prime Health Associates

  2. Jun 24

    Train Smarter. Age Better. Strength, Stability & Longevity with Andie Emmett, PT, DPT

    Send us Fan Mail Train Smarter. Age Better. Most people don't lose their health overnight. They lose it one movement, one habit, and one missed opportunity at a time. In this episode, Dr. Kevin White sits down with physical therapist Andie Emmett, PT, DPT, whose one-on-one approach to movement, strength, and recovery has made her one of Oklahoma's most sought-after physical therapists. This isn't just a conversation about pain. It's about building a body that stays strong, capable, and resilient for decades. Together they explore: • Why strength and stability matter more than you think • The hidden movement patterns behind chronic pain • Why weak glutes can lead to back problems • How to protect your shoulders before injuries happen • The importance of resistance training after 40 • Walking, CrossFit, Hyrox, and training intelligently • What separates people who thrive in their 70s and 80s from those who don't Along the way, Andie shares why she left the traditional high-volume healthcare model to create a practice centered around something increasingly rare: time, attention, and truly personalized care. Whether you're recovering from an injury, trying to perform at a higher level, or simply want to age with strength and independence, this episode offers practical insights you can start using today. Guest Andie Emmett, PT, DPT Whole Wellness Nichols Hills Plaza Oklahoma City Follow The Daily Apple for weekly conversations on longevity, performance, prevention, nutrition, exercise, and the science of living well. If you enjoyed this episode, please subscribe, leave a review, and share it with someone who's committed to living a longer, healthier life. Find Andie Emmett at Whole Wellness, Nichols Hills Plaza, Oklahoma City.  www.facebook.com/WholeWellnessLLC Follow The Daily Apple and leave a review to help more people find the show.  www.primehealthassociates.com Instagram: @KevinWhiteMD YouTube: @KevinWhiteMD Prime Health Associates

  3. Jun 16

    The Microplastics Problem Is Bigger Than Your Water Bottle

    Send us Fan Mail Most people worried about microplastics are focused on the wrong things. The receipts, the water bottles, the plastic cutting boards. Dr. Matt Campen has spent his career actually measuring what ends up in the human body, and the picture that's emerging looks a lot less like a consumer choice problem and a lot more like a food system problem. Dr. Kevin White sits down with Dr. Campen, a toxicologist and environmental health researcher at the University of New Mexico, to talk through what the science actually shows: where microplastics accumulate in the body, why the brain appears to hold more than any other organ, what his lab found when comparing plastic concentrations in healthy brains versus those with dementia, and why the biggest exposure vector isn't your water bottle. It's processed food, irrigated by groundwater running through plastic-contaminated agricultural fields. They also get into wildfire smoke as a largely overlooked driver of neuroinflammation, and why the recovery window is longer than most people realize. "I worry that the United States may end up being sentinels for the rest of the planet on what the health effects of microplastics are." This isn't a conversation about panic or dismissal. It's an honest look at where the science actually is, what it means for brain health and longevity, and why solving this one is going to take more than switching to a stainless steel bottle. Find Dr. Campen on LinkedIn. Instagram: @kevinwhitemd  YouTube: @kevinwhitemd  primehealthassociates.com Prime Health Associates

  4. Apr 21

    Psychedelics Can Rewrite the DNA of Trauma

    Send us Fan Mail Last Friday, President Trump signed an executive order directing the FDA to fast-track psychedelic medicines for mental health treatment. Joe Rogan texted him about Ibogaine. The president texted back. Fifty million federal dollars followed. You can have a lot of feelings about how that happened. Here is what is not political: a small group of neuroscientists and psychiatrists spent the last decade quietly building the scientific case that certain psychedelic compounds can do something no pill or therapy has ever done. Dr. David Rabin is one of them. He has been training clinicians, treating veterans with PTSD that responded to nothing, and running what has been called the largest controlled study of psychedelic medicines in the world. He published a paper in 2023 showing that MDMA assisted therapy produces measurable changes in the DNA of PTSD patients, at the level of the cortisol receptor, in direct proportion to how much better they got. Washington just showed up to a party that started ten years ago. Dr. Kevin White sits down with Dr. Rabin to talk about what MDMA is actually doing in the brain, why the safety hypothesis changes how you think about stress and chronic illness, what Ibogaine does to opioid receptors that nothing else can, and why most of the ketamine being prescribed right now is being given wrong. "Psychedelic medicines are to mental illness what antibiotics were to infection in the first half of the 20th century." The science was already there. Now find out what it actually says. Find more from Dr. Rabin at drdave.io and apolloneuro.com. Try the Apollo wearable at wearablehugs.com. His first book, A Simple Guide To Being Alive, is available at asimpleguidetobeingalive.com Follow The Daily Apple and leave a review to help more people find the show.  Instagram: @KevinWhiteMD  YouTube: @KevinWhiteMD www.primehealthassociates.com  Prime Health Associates

  5. Apr 14

    Veterinary Medicine Is Broken and Your Dog Is Paying for It

    Send us Fan Mail Most pet owners trust that regular vet visits, decent food, and a joint supplement are enough. Dr. Kevin Toman spent 35 years practicing that model. He doesn't believe it anymore. After four decades in clinical medicine, a personal MGUS diagnosis that pushed him toward integrative care, and a growing awareness of how poorly the profession was serving aging pets, he rebuilt his practice entirely around longevity. He now runs one of the only concierge veterinary practices in the country focused on extending healthspan, not just managing disease. If you don't have a pet, stay with this one. The conversation keeps landing back in the same place: the principles driving longevity in dogs and cats are the same ones driving it in humans. Rapamycin, caloric restriction, early cancer diagnostics, dental inflammation as a systemic disease driver, the failure of reactive medicine. Dr. Toman is applying an identical framework to a different patient population, and in some cases the data is cleaner because the studies are easier to run. Dr. Kevin White sits down with Dr. Toman to cover rapamycin's role in preventing and treating cancer in dogs and cats, why he's using it preventively in asymptomatic patients, why glucosamine and chondroitin don't work and what the research actually supports, how breed-specific risk changes everything about how a patient should be managed, the cancer navigation crisis facing pet owners in rural areas, and where early cancer diagnostics are heading for both species. "The relationships and the holistic care that are so important to lifestyle and longevity have disappeared from the veterinary lexicon." This one covers more ground than most pet health conversations get anywhere near. Find more from Dr. Toman at helpingpetslivelonger.com and freevetcall.com And follow The Daily Apple and leave a review to help more people find the show.  Instagram: @KevinWhiteMD  YouTube: @KevinWhiteMD www.primehealthassociates.com  Prime Health Associates

  6. Mar 24

    Still Heli-Skiing at 88: Frank's Blueprint for Never Slowing Down

    Send us Fan Mail What does it take to still be heli-skiing, competing in triathlons, and running beach stairs in your late eighties? In this episode, Dr. Kevin White travels to Malibu to sit down with Frank, an 88-year-old athlete, engineer, and adventurer, and Flavio, Frank's trainer of 35 years. Together, they pull back the curtain on what it actually takes to stay that functional, that active, and that sharp at an age when most people have long stopped trying. They cover Flavio's 90-minute three-component training structure, why flexibility and stability matter more than raw strength, and how Frank survived a helicopter crash and a mountain biking accident that broke his back and neck, and came back from both. Kevin also walks through the nutrition and supplement protocols he uses with his own patients, including creatine for cognitive support, magnesium L-threonate, managing insulin resistance, and why too much fruit in your smoothie may be doing more harm than good. Frank's philosophy is simple: exercise is a means to an end, not the goal itself. The goal is to keep doing the things that make life worth living. "Family, friends, take care of yourself. And never quit." If you want a model for what aging well actually looks like in practice, this episode is it. Follow The Daily Apple and leave a review to help more people find the show. www.primehealthassociates.com  Instagram: @KevinWhiteMD  YouTube: @KevinWhiteMD Prime Health Associates

4.6
out of 5
17 Ratings

About

We dive into all topics regarding the science of longevity along with some other subjects we find of interest with the hopes to provide useful information for everyone. This stems from our personal interest to optimize the human condition to not just live longer, but live better.

You Might Also Like