Dr. Emmanuella Amoako, a pediatric oncologist at Cape Coast Teaching Hospital in Ghana, is the winner of the 2026 Roux Prize. We talk with her about how she has used evidence to improve early diagnosis, expand access to treatment, and strengthen locally led cancer research, including a shared-care service that brings treatment closer to families and a program that trains parents to help detect childhood cancer early. Learn more about Dr. Amoako's work: https://www.healthdata.org/news-events/newsroom/videos/roux-prize-2026-recipient-dr-emmanuella-amoako Nominations for the 2027 Roux Prize are open on November 1: https://www.healthdata.org/about/awards/roux-prize __________________ Transcript Rhonda Stewart: Welcome to Global Health Insights, a podcast from IHME, the Institute for Health Metrics and Evaluation. I’m Rhonda Stewart. In this episode, we’ll hear from Dr. Emmanuella Amoako, winner of the 2026 Roux Prize. Known affectionately to her patients as Dr. Ella, she’s a pediatric oncologist advancing childhood cancer care in Ghana. The Roux Prize, supported by David and Barbara Roux and awarded by IHME, recognizes a person who has used health evidence in bold ways to make people healthier and includes a $100,000 award. Childhood cancer survival exceeds 80% in many high-income countries, compared with less than 30% in many African settings. As lead pediatric oncologist at Cape Coast Teaching Hospital, Dr. Amoako established a shared care pediatric oncology service in 2019, bringing treatment closer to families who had traveled up to nine hours to reach specialist care. The service has since cared for more than 150 children. Dr. Amoako also developed COMPASS, a community program that trains parents of childhood cancer survivors and primary care workers to recognize warning signs and guide families to specialized care. And through the African Cancer Atlas, she is helping build evidence that better represents African patients in cancer research. Thank you so much for joining us. Dr. Amoako. What drew you to pediatric oncology? Was there a particular moment or a particular patient that made you decide this was your life’s work? Dr. Emmanuela Amoako: Thank you very much for having me. Pediatric oncology, I always – whenever I’m asked this question, I always laugh because it was like the last thing on my list when I became a pediatrician. I always used to think I would do something related to maybe procedures or just genetics. I always wanted to do genetics. And then I quite remember as a resident rotating through the pediatric oncology rotation, I sat once with a senior colleague of mine, Dr. Nihad Salifu, and she was asking me like what my future plans were. And then I looked at her and I’m like well, it’s not going to be oncology. I want to do something I want, like genetics. And then she looked at me like very seriously and said yeah, if you do genetics, just like clinical genetics here in Ghana, what are you going to use it for? I’m like, well, I’ll make the diagnosis – like then what? Then what? And I’m like okay, I do not know. And she’s like, well, cancer genetics is emerging. If you really want to do something in genetics, you should consider it. Go read on it and then let me know what your thoughts are. I mean the next obvious thing I said was, yeah, you just want me to do it because it has oncology in it, and she said, no, no, really, just go think about it. So that sat with me for a bit. And then when I completed my residency and went back to the station where I was to practice as a general pediatrician – so I started in September 2019 and then in November 2019, this child comes in to us at the Cape Coast Teaching Hospital. So a 14-year-old boy, he had lymphoma – he was very sick, and he had one of the side effects that comes with that particular cancer, which is the cells break down quite quickly, we call it tumor lysis syndrome. When the cells break down, there’s this overload on the kidneys, so he was in acute kidney failure. He was very ill. Now at the time in Cape Coast, what we always did was we would see the child and when we suspected cancer we referred to Accra. So just for context, Accra to Cape Coast is about a four-hour drive. And so we had to put this child in an ambulance to move to Accra. But I picked up the phone, I called the person who trained me in Accra and I called her, Prof. Lorna Renner. And I’m like, Prof., I have this child who is very sick. I need to move them. Do you have a bed? Do you have space? And she just is like, Ella, from what you’re describing, you know this child is not going to be able to travel, right? I’m like, yeah, Prof., but I cannot do anything here in Cape Coast. She’s like, well, I trained you, so you can try. I can guide you from here. And I’m like, Prof., I don’t think I want to get my hands dirty. And she’s like, well, I believe you can do something. It’s two things: He’s not going to make the trip. He would probably die before getting to care, so you need to do something. And so thankfully, Cape Coast is very close like the, what do you call them? The units are very closely knit. So I call the dialysis unit. The were willing to hemodialyze the child. I called – at that time the service that was provided there was for adult cancer, so I called the pharmacist. They were able to prepare some chemo. And so we would give chemo, would dialyze. We would give some chemo, would dialyze. And he lived. He actually lived. Yeah. And I remember when we were out of the woods, I called Prof. Renner. I’m like, Prof., I’m going to send him now his stable. She’s like, you’ve done the hard part. You can do whatever is left. I’m not taking this patient. Okay? So I’m like, wow. Okay. So she sent the protocols. And it was not just me – there was a team that was there that was willing, and we worked with him, and it was quite timely, I must say. So subsequently, every child that came that was not even very ill, she’s like, well, you can do it. I’m not gonna take this patient. It was quite timely because then 2020 COVID hits, and mind you, Cape Coast serves three different regions and one of the farthest regions would be like nine hours from Accra, the center. And most of the patients came from there. So then it was like, well, we would have to start treating children in Cape Coast. And so that piqued my interest in pediatric oncology, and I had to go and get formal training. So 2019, 2020, I didn’t have formal training in pediatric oncology but I was treating the patients, and then 2021 I had to go get formal training. Rhonda Stewart: That’s incredible. So it sounds like your mentor really changed your career by pushing you to think about then what. So you were going to do genetics, but then what? And just to keep going. Dr. Emmanuela Amoako: Yeah. Rhonda Stewart: Then to give you the confidence, to push you, to say that you could treat this child locally, which then made it possible for you to treat other children locally. That’s incredible. Dr. Emmanuela Amoako: Yeah. And I must say that it’s been amazing being in this field. Rhonda Stewart: Wow, that’s fantastic. Let’s talk a little bit about the survival gap. In many high-income countries, more than 80% of children with cancer survive, but in many African settings, unfortunately, fewer than 30% do. What drives that gap, and what part of that gap can be closed by having better evidence? Dr. Emmanuela Amoako: Yeah, sad, these statistics. I mean, I think it’s always daunting when you hear it and to think, actually, it’s quite interesting because 80% survive in high-income countries, less than 30% in low- and middle-income countries. However, the burden of disease, 80% of the cases are actually found in low- and middle-income countries. And only 20% of those cases are found in high-income countries. So it’s quite a very weird balance. But yeah, there’s a lot of data evidence to suggest that people present late to clinical settings, people abandon treatment, there’s a lot of toxic death. And for me, most important is the kind of protocols that we used are all adapted from clinical trials that were conducted in people that were not or are not of African descent. Rhonda Stewart: Right. Dr. Emmanuela Amoako: I mean, it is well known that clinical trials really across the world have only about 2% of people of African descent. Not to talk about clinical trials in Africa, and then in children in Africa, which barely exist. So again, if these clinical trials are not happening in a certain population, but then the protocols are adapted to them, would it really work? So then I’ve always asked the question, is it that we have more aggressive disease, or the protocols are just not working? Again, when it comes to genetics and genomics, it’s not been fully studied in people of African descent. Only about 2% to 3% of the global genome data bank consists of people of African descent. So we really do not understand the genetic basis of the cancers that we do see in our children. Rhonda Stewart: You mentioned Cape Coast with the example of your 14-year-old patient. And with respect to shared care at Cape Coast, before 2019, as you mentioned, families sometimes had to travel up to nine hours to reach specialists. Tell us how you designed that shared care service and what’s changed for the children who’ve been treated – and it’s more than 150 children at this point. Dr. Emmanuela Amoako: Yeah. So again, that initial conversation with Prof. Renner, like, you know what, I would guide and you can treat, I’ll send you the protocols, I’ll make sure I guide you, was what gave the whole idea of the shared care center. And so what we started with was to treat critically ill patient