Zero Pain Philosophy

Zero Pain Philosophy

Zero Pain Philosophy is here to help veterinary professionals worldwide achieve Analgesic Excellence in your clinic. Established by vet specialists Matt Gurney & Carl Bradbrook, we offer a variety of educational resources to help spread pain management know how including both free and paid content including podcasts, pain updates, webinars and a telemedicine service. Our content is delivered by European & American Specialists in Veterinary Anaesthesia & Analgesia. Resources are for vet professionals: pet owners - ask your vet to use our telemedicine service to seek case advice.

  1. 07/26/2025

    S2:E9 DogMA - keeping dogs moving

    Our latest podcast discusses the newly launched DogMA app with researchers Dr Natasha Clark and Professor Eithne Comerford.  Mobility issues from musculoskeletal diseases, like osteoarthritis, affect around 200,000 dogs annually, posing a significant challenge to their health and welfare. Although these diseases can affect dogs of any age, owners often miss early, subtle signs of gait abnormalities, leading to late diagnosis of osteoarthritis.  The DogMA app was developed to address this by enabling early detection of mobility problems, including subtle signs of discomfort or decline often overlooked in routine care.  DogMA is supported by scientific research led by Dr. Natasha Clark at the University of Liverpool, under the supervision of Professors Eithne Comerford and Karl Bates, in collaboration with Dogs Trust.  By using the app for regular assessments, users can also contribute anonymized data to ongoing research at the University of Liverpool, helping to advance the understanding of canine mobility across the UK. References Here is the link to the paper discussed in today’s podcast: Clark NL, Bates KT, Harris LK, Tomlinson AW, Murray JK, Comerford EJ. GenPup-M: A novel validated owner-reported clinical metrology instrument for detecting early mobility changes in dogs. PLoS One. 2023 Dec 27;18(12):e0291035. doi: 10.1371/journal.pone.0291035. PMID: 38150469; PMCID: PMC10752556. University of Liverpool page launching DogMA https://www.liverpool.ac.uk/life-course-and-medical-sciences/research/dogma/ Download the app for free from your app store: Android: DogMA in the Google Play Store iOS: DogMA in the Apple App Store This is the paper documenting radiographic and clinical OA in 23% of dogs less than 4 years of age: Enomoto M, de Castro N, Hash J, Thomson A, Nakanishi-Hester A, Perry E, Aker S, Haupt E, Opperman L, Roe S, Cole T, Thompson NA, Innes JF, Lascelles BDX. Prevalence of radiographic appendicular osteoarthritis and associated clinical signs in young dogs. Sci Rep. 2024 Feb 3;14(1):2827. doi: 10.1038/s41598-024-52324-9. PMID: 38310147; PMCID: PMC10838335.  These are the COAST guidelines: Cachon T, Frykman O, Innes JF, Lascelles BDX, Okumura M, Sousa P, Staffieri F, Steagall PV, Van Ryssen B. COAST Development Group's international consensus guidelines for the treatment of canine osteoarthritis. Front Vet Sci. 2023 Aug 3;10:1137888. doi: 10.3389/fvets.2023.1137888. PMID: 37601753; PMCID: PMC10436090.

    36 min
  2. 05/08/2025

    S2:E7 Exploring botulinum toxin A for pain management

    Dr Robert Trujanovic is an EBVS European Specialist in Veterinary Anaesthesia & Analgesia. In our latest podcast we talk to Robert to share his experience of using botulinum toxin A in pain management in dogs. Robert is leading the field on this subject and brings his experience of interventional pain management to our Zero Pain community. We explore What is the mechanism of action of BT? What sort of pain cases is BT used for in human medicine? Can you please tell us about some cases where you have successfully used BT in dogs (any feline experience) Are there some practical considerations you would like to mention? References ·      Pioneering pain management with botulinum toxin type A: From anti-inflammation to regenerative therapies. Hamta Rahmatipour, Salar Mohammadi Shabestari, Soheila Zamanlui Benisi, Hamidreza Samadikhah   ·      Botulinum toxin for the treatment of chronic pain. Review of the evidence. Roberto Carlo Rivera Día, Mario Andrés Arcila Lotero, María Victoria Avellaneda Suarez, Sara Echeverri Saldarriaga, Manuela Gómez Martínez   ·      Botulinum Toxin in Chronic Lateral Epicondylitis, from Tendon to Muscle Approach—A Review   ·      Transforaminal versus Intra-Articular Facet Corticosteroid Injections for the Treatment of Cervical Radiculopathy: A Randomized, Double-Blind, Controlled Study N.J. Bureau, T. Moser, J.H. Dagher, D. Shedid, M. Li, P. Brassard and B.E. Leduc   ·      Retrodural space of Okada in the posterior ligamentous complex region: clinical and anatomical findings relevant to lumbar interlaminar epidural injection

    39 min
  3. 10/11/2024

    S2:E4 Modifying the Microbiome to Minimise Pain

    In our latest podcast, Modifying the Microbiome to Minimise Pain, Matt talks to Dr Siobhain O’Mahony, a leading academic in microbiome research. Dr O’Mahony has published work within human medicine, examining the link between the microbiome and pain outcomes after surgery. And we ask, ‘How could this translate into our field of veterinary pain management?’  We also touch upon what we should eat ourselves and ask whether we are feeding our pets correctly. References for shownotes The gut microbiota as a key regulator of visceral pain (2017) The gut microbiota in persistent post-operative pain following breast cancer surgery https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11137075/ Stevens, Christina et al. “Gut Microbiome and Osteoarthritis: Insights From the Naturally Occurring Canine Model of Osteoarthritis.” Arthritis & rheumatology (Hoboken, N.J.), 10.1002/art.42956. 19 Jul. 2024, doi:10.1002/art.42956 Stewart, H L et al. “Differences in the equine faecal microbiota between horses presenting to a tertiary referral hospital for colic compared with an elective surgical procedure.” Equine veterinary journal vol. 51,3 (2019): 336-342. doi:10.1111/evj.13010 Stewart, Holly L et al. “Changes in the faecal bacterial microbiota during hospitalisation of horses with colic and the effect of different causes of colic.” Equine veterinary journal vol. 53,6 (2021): 1119-1131. doi:10.1111/evj.13389 Jan S Suchodolski https://pubmed.ncbi.nlm.nih.gov/34514619/ The Dysbiosis Index (DI) is a validated quantitative PCR assay for canine fecal samples that measures the abundance of seven important bacterial taxa and summarizes the results as one single number.  The DI can be used to assess the microbiome in clinical patients over time and in response to therapy (eg, fecal microbiota transplantation).

    50 min

About

Zero Pain Philosophy is here to help veterinary professionals worldwide achieve Analgesic Excellence in your clinic. Established by vet specialists Matt Gurney & Carl Bradbrook, we offer a variety of educational resources to help spread pain management know how including both free and paid content including podcasts, pain updates, webinars and a telemedicine service. Our content is delivered by European & American Specialists in Veterinary Anaesthesia & Analgesia. Resources are for vet professionals: pet owners - ask your vet to use our telemedicine service to seek case advice.

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