Basics to Brilliance: Haematology Podcast

Basics To Brilliance

Welcome to Basics to Brilliance, the podcast created to supplement & bolster your knowledge of Haematology.Featuring a two way, non-didactic conversational-style Q&A between the SpR and SHO, this podcast will be your pocket companion no matter where you are.We aim to cover: - Malignant and non-malignant topics - Science/lab detail - UK guidelines, hallmark trials and how these translate into clinical practice - Future research directions - The whole syllabus for FRCPath part 1 All readily accessible and completely free of charge!For every budding haematologist out there, we hope this podcast aids you in your endeavours and fills you with interest and excitement for the brilliant world of Haematology. Warmest Regards,Dr. EverdenDr. FaseyDr. Jafri Disclaimer: This podcast is intended as a revision aid and should not be used for the medical management of patients. Guidelines in the initial episodes span 2023/2024. We aim to update our content in accordance with the most recent available guidelines when possible.  This podcast is CPD accredited by the Royal College of Pathologists UK 

  1. Jun 30

    Von Willebrand Disease: Diagnosis and Lab Tests

    Feedback 'Basics to Brilliance: Haematology Podcast' has been accredited for CPD credit by the Royal College of Pathologists UK.  Medical professionals and clinical scientists holding career-grade positions, who are registered with any of the Royal Colleges for CPD, will be eligible to earn 1 credit for every hour of learning.  Email: basicstobrilliancehaem@gmail.com Insta: BasicstoBrilliance X: @basics_2_brill Send us your feedback!

  2. Jun 30

    Von Willebrand Disease: The Basics

    Feedback Clinical Presentation Classifications of VWD 'Basics to Brilliance: Haematology Podcast' has been accredited for CPD credit by the Royal College of Pathologists UK.  Medical professionals and clinical scientists holding career-grade positions, who are registered with any of the Royal Colleges for CPD, will be eligible to earn 1 credit for every hour of learning.  Email: basicstobrilliancehaem@gmail.com Insta: BasicstoBrilliance X: @basics_2_brill Send us your feedback!

    Von Willebrand Disease: The Basics

  3. Jun 6

    Haemophilia C

    Feedback Haider steps out of the shadows.... Make sure you send us the questions you're too afraid to ask your haem reg (or consultant) - email address below! 'Basics to Brilliance: Haematology Podcast' has been accredited for CPD credit by the Royal College of Pathologists UK.  Medical professionals and clinical scientists holding career-grade positions, who are registered with any of the Royal Colleges for CPD, will be eligible to earn 1 credit for every hour of learning.  Email: basicstobrilliancehaem@gmail.com Insta: BasicstoBrilliance X: @basics_2_brill Send us your feedback!

    Haemophilia C

  4. May 24

    Lab Diagnostic Techniques for Haemoglobinpathies and Thalassemias (with Dr. Noemi Roy)

    Feedback We are delighted to have Dr. Noémi Roy Consultant Haematologist at Oxford University Hospitals NHS Foundation Trust join us for this very special episode! 'Basics to Brilliance: Haematology Podcast' has been accredited for CPD credit by the Royal College of Pathologists UK.  Medical professionals and clinical scientists holding career-grade positions, who are registered with any of the Royal Colleges for CPD, will be eligible to earn 1 credit for every hour of learning.  Email: basicstobrilliancehaem@gmail.com Insta: BasicstoBrilliance X: @basics_2_brill Send us your feedback!

    Lab Diagnostic Techniques for Haemoglobinpathies and Thalassemias (with Dr. Noemi Roy)

  5. May 2

    Red Cell Basics

    Feedback Welcome to the Red Cell Series! Timestamps and notes to follow... 'Basics to Brilliance: Haematology Podcast' has been accredited for CPD credit by the Royal College of Pathologists UK.  Medical professionals and clinical scientists holding career-grade positions, who are registered with any of the Royal Colleges for CPD, will be eligible to earn 1 credit for every hour of learning.  Email: basicstobrilliancehaem@gmail.com Insta: BasicstoBrilliance X: @basics_2_brill Send us your feedback!

    Red Cell Basics

  6. Apr 11

    Haemophilia B, Gene Therapy

    Feedback Timestamps to follow! 'Basics to Brilliance: Haematology Podcast' has been accredited for CPD credit by the Royal College of Pathologists UK.  Medical professionals and clinical scientists holding career-grade positions, who are registered with any of the Royal Colleges for CPD, will be eligible to earn 1 credit for every hour of learning.  Email: basicstobrilliancehaem@gmail.com Insta: BasicstoBrilliance X: @basics_2_brill Send us your feedback!

    Haemophilia B, Gene Therapy

  7. Feb 8

    Dilemmas in Haemophilia

    Feedback This is a discussion about possible factors and strategies to consider and should not be used as a guideline for clinical practice. Always discuss complicated cases with the attending H&T consultant. 00:52 Intro 01:30 Case 1: 41M Severe Haemophilia A, acute MI needing PCI Try the 4 steps! Bleeding RiskAnticoagulant characteristicsIntensity of anticoagulant (prophylactic vs therapeutic)Duration of anticoagulant therapy11:20 Cardiac Disease in Haemophilia: thoughts and considerations  20:40 Case 1: a potential algorithm in action 24:15 Case 2: 60M Moderate Haemophilia A, positive cardiac Hx, AF on ECG 33:30 Case 3: Moderate Haemophilia A, lobectomy, DVT on USS doppler of leg 40:00 Golden nuggets with a side of ffries 'Basics to Brilliance: Haematology Podcast' has been accredited for CPD credit by the Royal College of Pathologists UK.  Medical professionals and clinical scientists holding career-grade positions, who are registered with any of the Royal Colleges for CPD, will be eligible to earn 1 credit for every hour of learning.  Email: basicstobrilliancehaem@gmail.com Insta: BasicstoBrilliance X: @basics_2_brill Send us your feedback!

    Dilemmas in Haemophilia

  8. Jan 25

    Acquired Haemophilia A

    Feedback 00:52 Intro and chuckles 01:40 Case study: 75M, left calf swelling, put on DOAC, 24 hrs later haematoma and deep bleed on CT 06:00 General information Elderly (>65), Mortality 8-40%Common presentations: GI and UG bleeding, Retroperitoneal and muscle bleeds (compartment syndrome)Ptegnancy, TTP, Malignancy (15%), Autoimmune disease (17%)08:56 Pathogenesis and diagnosis: AutoAb against F8 *Bethesda units do not correlate with bleeding phenotype in Acquired HA- second orfer kinetics*HistoryAPTT, PT (isolated raised APTT)Mixing studies: 50/50 or 80/20 mixFactor Assays (**Intrinsic**)Decreased Factor VIII + Non-paralellism -> Bethesday Assay20:20 Non-clotting investigations 22:05 Treatment MDT + Comprehensive Care Center escalationRICE., TXA, Bypassing agentsLimit iatrogenic bleedingReview medicationsPregnancy: birth plan!!!  inhibitor can cross palcentaSteroid +/- Cyclophosphamide27:10 Bypassing Agents in Acquired Haemophilia A FENOC + EACH2 study: FEIBA vs NovoSeven = No difference in bleeding/thrombosis rates- more info at 33:25 for EACH2Obizor can be titrated according to response whereas FEIBA and NovoSeven cannotEmicizimab +/- Immunosuppression  = Not currently licesnsed in the UK 32:25 Inhibitor eradication Mean time to remission: 5 weeksGood prognostic markers: FVIII 1 or more, Inhibitor titre Steroids + Cyclophosphamide -> Steroids + Cyclo + RituximabBiggest cause of death: infection36:45 Follow up  Weekly FVIII levels and inhibitor monitoring till remission then monthly for 6 months then 2-3 monthly for a yearPlanned procedure; FVIII level38:45 Golden Nuggets 'Basics to Brilliance: Haematology Podcast' has been accredited for CPD credit by the Royal College of Pathologists UK.  Medical professionals and clinical scientists holding career-grade positions, who are registered with any of the Royal Colleges for CPD, will be eligible to earn 1 credit for every hour of learning.  Email: basicstobrilliancehaem@gmail.com Insta: BasicstoBrilliance X: @basics_2_brill Send us your feedback!

    Acquired Haemophilia A
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Ratings & Reviews

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2 Ratings

About

Welcome to Basics to Brilliance, the podcast created to supplement & bolster your knowledge of Haematology.Featuring a two way, non-didactic conversational-style Q&A between the SpR and SHO, this podcast will be your pocket companion no matter where you are.We aim to cover: - Malignant and non-malignant topics - Science/lab detail - UK guidelines, hallmark trials and how these translate into clinical practice - Future research directions - The whole syllabus for FRCPath part 1 All readily accessible and completely free of charge!For every budding haematologist out there, we hope this podcast aids you in your endeavours and fills you with interest and excitement for the brilliant world of Haematology. Warmest Regards,Dr. EverdenDr. FaseyDr. Jafri Disclaimer: This podcast is intended as a revision aid and should not be used for the medical management of patients. Guidelines in the initial episodes span 2023/2024. We aim to update our content in accordance with the most recent available guidelines when possible.  This podcast is CPD accredited by the Royal College of Pathologists UK 

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