Your Checkup: Patient Education Health Podcast

Ed Delesky, MD and Nicole Aruffo, RN
  • 5.0 (17)
  • MEDICINE
  • UPDATED WEEKLY

Ever leave the doctor’s office more confused than when you walked in? Your Checkup: Health Conversations for Motivated Patients is your health ally in a world full of fast appointments and even faster Google searches. Each week, a board certified family medicine physician and a pediatric nurse sit down to answer the questions your doctor didn’t have time to. From understanding diabetes and depression to navigating obesity, high blood pressure, and everyday wellness—we make complex health topics simple, human, and actually useful. Whether you’re managing a condition, supporting a loved one, or just curious about your body, this podcast helps you get smart about your health without needing a medical degree. Because better understanding leads to better care—and you deserve both.

  1. 5D AGO

    107: A New GLP1 Weight Loss Pill? What You Need to Know About Orforglipron (Foundayo)

    A GLP-1 that comes as a simple daily pill and can be taken with or without food sounds like a small change, until you think about real life. We’re celebrating two years of Your Checkup and sharing what’s surprised us most, from listeners across the country and around the world to the messages that stick with us, like families changing habits after a heart attack or patients bringing notes back after our diabetes episodes. Then we get practical about a timely healthcare headline: orforglipron, the newly approved oral GLP-1 receptor agonist from the same broader medication family as Ozempic and Wegovy. We talk through how GLP-1 medications work on appetite and fullness, what the 72-week clinical trial data actually shows for weight loss, and why “10% of body weight” isn’t a cosmetic metric but a medically meaningful shift for cardiometabolic health. We also dig into type 2 diabetes results, including A1C drops and how many people reached key treatment goals, plus the side effects you should expect with dose starts and increases. Finally, we compare the pill’s outcomes with injectable options like Wegovy and Zepbound, and we name the real problem many patients face now: access. Cost, insurance coverage, and convenience often decide more than the science does. If you found this helpful, subscribe, share it with a loved one or neighbor, and leave a quick review so more patients can find clear, balanced health education. Send us a (voice ) message with this link, we would love to hear from you. Standard message rates may apply. Support the show Production and Content: Edward Delesky, MD, DABOM & Nicole Aruffo, RN Artwork Rebrand and Avatars: Vantage Design Works (Vanessa Jones)  Website: https://www.vantagedesignworks.com/ Instagram: https://www.instagram.com/vantagedesignworks?igsh=aHRuOW93dmxuOG9m&utm_source=qr Original Artwork Concept: Olivia Pawlowski

    27 min

  2. MAR 30

    106: Why You’re Always Tired — The 3 Real Causes (And How to Fix Them)

    You wake up tired, push through the day tired, and somehow still feel tired after sleeping. That frustrating loop is one of the most common concerns we hear in primary care, and it usually has a pattern. We walk through a simple, clinician-style way to think about fatigue that doesn’t spiral into guesswork: sleep, nutrition, or an underlying medical issue. If you’ve ever wondered whether you’re “just not sleeping enough” or if something deeper is going on, we help you separate sleepy from truly drained and figure out what to try first. We start with sleep quality, not just sleep time. We talk sleep efficiency, why spending too long in bed can make insomnia worse, and why a consistent wake-up time often matters more than an early bedtime. You’ll also hear practical sleep hygiene tips you can actually use, plus a surprisingly effective “do your words” cognitive shuffling technique for nights when your brain refuses to power down. Then we shift to energy from the inside out: steady meals, balanced macros, hydration, and a few lab-related topics that come up often in real life. We discuss B12, vitamin D, and the growing conversation around non-anemic iron deficiency, including ferritin and why “normal” reference ranges don’t always match how you feel. We also cover red flags for sleep apnea, how mood and stress can drain you, and when it’s time to get checked out. If the afternoon crash is your daily enemy, we leave you with a simple alternative to more caffeine. If this helps you, subscribe, share it with a tired friend, and leave a review so more people can find practical, patient-friendly medical guidance. Send us a (voice ) message with this link, we would love to hear from you. Standard message rates may apply. Support the show Production and Content: Edward Delesky, MD, DABOM & Nicole Aruffo, RN Artwork Rebrand and Avatars: Vantage Design Works (Vanessa Jones)  Website: https://www.vantagedesignworks.com/ Instagram: https://www.instagram.com/vantagedesignworks?igsh=aHRuOW93dmxuOG9m&utm_source=qr Original Artwork Concept: Olivia Pawlowski

    33 min

  3. MAR 23

    105: New Cholesterol Guidelines 2026: What Your Numbers Mean & What to Do

    Cholesterol advice has been stuck in “it depends” for years, and we wanted something more concrete you can actually use. So we dig into the 2026 American Heart Association cholesterol guidelines and translate them into plain language: the new LDL cholesterol thresholds, what counts as borderline or high, and why having clear targets can make shared decision-making with your doctor, nurse, or PA a lot less vague. We also explain why non-HDL cholesterol can be a helpful “total bad cholesterol” goal, plus the HDL and triglyceride ranges that still shape overall cardiovascular risk.  One update we’re especially excited about is the class one recommendation to check lipoprotein(a) at least once in adulthood. Lp(a) is largely genetic, doesn’t reliably drop with diet, exercise, or standard statins, and can raise heart attack and stroke risk even when the rest of your lipid panel looks normal. We walk through what the numbers mean, how common elevation is, and how this single test can change the intensity of prevention for you and prompt testing for family members.  We also cover the new Prevent equation for 10-year risk, including how it accounts for factors like diabetes and kidney function, and why the risk category cutoffs have shifted. From there, we lay out the foundation of dyslipidemia treatment: heart-healthy eating, consistent physical activity, weight goals, smoking cessation, and limiting alcohol. And when lifestyle isn’t enough, we get practical about medications, including statins, ezetimibe, PCSK9 inhibitors, inclisiran, and bempedoic acid, along with straight talk about safety and the harm of online statin myths.  If you care about prevention, family history, or simply want a clearer plan for your next lab review, this one is for you. Subscribe, share this with a friend who’s confused by cholesterol results, and leave a review with the one question you want your clinician to answer about your heart disease risk. Send us a (voice ) message with this link, we would love to hear from you. Standard message rates may apply. Support the show Production and Content: Edward Delesky, MD, DABOM & Nicole Aruffo, RN Artwork Rebrand and Avatars: Vantage Design Works (Vanessa Jones)  Website: https://www.vantagedesignworks.com/ Instagram: https://www.instagram.com/vantagedesignworks?igsh=aHRuOW93dmxuOG9m&utm_source=qr Original Artwork Concept: Olivia Pawlowski

    49 min

  4. MAR 16

    104: How Smartphones Affect Mental Health: Anxiety, Depression, and Screen Time Explained

    Your phone might be doing more than stealing time. It may be quietly taxing your mood, your attention, and the basic habits that keep you well. We found a fascinating research study that tested a simple but radical idea: block mobile internet access on a smartphone for two weeks while still letting people call and text, and then measure what changes in mental health, well-being, and focus.  We walk through how the researchers designed the experiment with 467 adults, why this kind of randomized setup helps answer the causation question, and what they actually measured: depression, anxiety, social anxiety, life satisfaction, positive and negative mood, plus a real sustained attention task instead of just “I feel more focused.” Then we get into the headline-worthy outcomes, including the stat that about 91% of participants improved in at least one area and the surprising attention boost researchers estimated as roughly equivalent to reversing about ten years of age-related decline.  We also dig into the “why” behind the results, because the point isn’t to demonize smartphones. When the constant portal to social media, news, email and scrolling disappears, many people naturally spend more time sleeping, moving their bodies, getting outside and seeing other humans in real life. We talk about who may benefit most, what the limitations are, and practical ways to test the idea without going extreme: deleting the stickiest apps, setting phone-free zones, and experimenting with computer-only access. If you want a simple starting point, we leave you with one challenge you can try this week. Subscribe, share this with a friend who feels phone-tired, and leave a review with what boundary you’re trying first. Send us a (voice ) message with this link, we would love to hear from you. Standard message rates may apply. Support the show Production and Content: Edward Delesky, MD, DABOM & Nicole Aruffo, RN Artwork Rebrand and Avatars: Vantage Design Works (Vanessa Jones)  Website: https://www.vantagedesignworks.com/ Instagram: https://www.instagram.com/vantagedesignworks?igsh=aHRuOW93dmxuOG9m&utm_source=qr Original Artwork Concept: Olivia Pawlowski

    32 min

  5. MAR 9

    103: What They Say You Should Actually Eat Everyday

    Headlines argue. We read the document. This week we unpack the newest dietary guidelines with a clear, practical lens: what the recommendations actually say, why they still look a lot like Mediterranean and DASH patterns, and how to turn them into everyday choices that reduce risk without wrecking joy. We start with the big shift that matters most—focusing on overall dietary patterns instead of obsessing over single nutrients—then dig into the hot spots that shape real health outcomes. We cut through the noise on saturated fat by pairing mechanism with food context, explaining why a simple cap exists and how whole foods complicate the picture. Added sugar gets a brighter spotlight: from the outsized impact of sugar-sweetened beverages to easy swaps like unsweetened tea and low-sugar prebiotic sodas that don’t torpedo your day. We revisit whole grains for their fiber and cardiometabolic benefits, highlight protein variety to reduce reliance on processed meats, and pull forward the growing evidence on ultra-processed foods and why they often lead to overeating even when macros match. Alcohol guidance is evolving too. We talk candidly about shifting from “maybe helpful” to “not necessary,” the ripple effects on sleep and recovery, and simple ways to keep the ritual while skipping the drag on health. Throughout, we remind listeners that population-level guidelines are meant to lower risk across millions of lives; personalized nutrition still belongs with you and your clinician or dietitian. Our goal is a calm, confident roadmap: fewer absolutes, more usable habits, and a pattern you can actually maintain. If this helps you stress less about food, tap follow, share it with a friend who loves a good label read, and leave a quick review so others can find the show. Send us a (voice ) message with this link, we would love to hear from you. Standard message rates may apply. Support the show Production and Content: Edward Delesky, MD, DABOM & Nicole Aruffo, RN Artwork Rebrand and Avatars: Vantage Design Works (Vanessa Jones)  Website: https://www.vantagedesignworks.com/ Instagram: https://www.instagram.com/vantagedesignworks?igsh=aHRuOW93dmxuOG9m&utm_source=qr Original Artwork Concept: Olivia Pawlowski

    30 min

  6. MAR 5

    102: 3 Surprising Health Risks You Might Be Ignoring

    Three ordinary habits—puzzling, pouring, and brushing—carry extraordinary power over long-term health. We unpack new and notable research on cognitive health, colorectal cancer risk, and cardiovascular disease, then turn it into simple actions you can actually keep. First, we explore why puzzles and other structured brain challenges may strengthen executive function, attention, and visuospatial skills. Large-scale studies of board games and crosswords point to lower dementia risk, and the mindfulness angle is compelling: focused, tactile tasks can quiet stress cycles and improve mood. We’re honest about the evidence gaps too—puzzles haven’t been trialed as formal stress therapies—but the low-friction habit still earns a spot in your daily routine, especially if you crave small wins or navigate ADHD. Next, we challenge the comfort of “moderate” drinking by looking at lifetime alcohol intake and colorectal cancer. The dose-response signal is clear: more drinks over more years raise risk, with rectal cancer showing the steepest climb. There’s practical hope as well—former drinkers see fewer precancerous adenomas—so dialing back weekly totals, adding alcohol-free days, and keeping up with screening can move the needle. The takeaway isn’t alarm; it’s agency. We close with two underappreciated drivers of heart disease: ultra-processed foods and gum health. Evidence now ties higher UPF intake to more cardiovascular events, while updated scientific statements map how periodontal bacteria and chronic inflammation stress blood vessels, elevate clotting risk, and push up heart attack and stroke rates. The fix is refreshingly doable: shift groceries toward minimally processed staples, build batch-cook routines, brush and clean between teeth daily, and keep regular dental visits. We also name the inequities—insurance gaps, limited access, time off work—and why better oral care access belongs in any heart health strategy. If this helped you rethink one small daily choice, tap follow, share it with a friend, and leave a quick review so others can find the show. Your next healthy habit might start right here. Send us a (voice ) message with this link, we would love to hear from you. Standard message rates may apply. Support the show Production and Content: Edward Delesky, MD, DABOM & Nicole Aruffo, RN Artwork Rebrand and Avatars: Vantage Design Works (Vanessa Jones)  Website: https://www.vantagedesignworks.com/ Instagram: https://www.instagram.com/vantagedesignworks?igsh=aHRuOW93dmxuOG9m&utm_source=qr Original Artwork Concept: Olivia Pawlowski

    17 min

  7. MAR 2

    101: Why Nutrition Advice Keeps Changing (And What To Trust)

    Ever wondered who really decides what America should eat—and how those choices land on your tray at school, your hospital menu, or your family’s grocery list? We take you behind the scenes of the U.S. dietary guidelines, charting the history from the low-fat era and the iconic food pyramid to today’s more pattern-based approach. Along the way, we explore the messy overlap of science, policy, economics, and everyday life, and why sweeping changes rarely make it into federal guidance even when headlines suggest otherwise. We break down what the guidelines actually are—a population-level tool shaped by USDA and HHS. You’ll hear how evidence evolves, how advisory committees weigh it, and where industry and agricultural interests push at the edges. Just as important, we zoom in on the realities that drive eating habits: access to fresh food, time to cook, stable housing, kitchen equipment, and tight budgets. It’s one thing to recommend more vegetables and fish; it’s another to make those options affordable and available in every zip code. By reframing the guidelines as a floor instead of a ceiling, we point to what matters most for public health today: fewer sugar-sweetened beverages, less ultra-processed food, smarter portions, and more whole foods. We also preview what’s coming next in our series—deep dives into saturated fat, added sugars, protein needs, ultra-processed foods, and alcohol—assessing where the evidence is strong and where it’s still emerging. If you’ve ever asked, “Are these rules outdated or influenced?” or “Should I follow them at all?”, this conversation gives you the context to decide—and the language to advocate for better access and smarter policy in your community. If you found this useful, follow the show, share it with a friend, and leave a quick review telling us what part of nutrition policy you want us to tackle next. Send us a (voice ) message with this link, we would love to hear from you. Standard message rates may apply. Support the show Production and Content: Edward Delesky, MD, DABOM & Nicole Aruffo, RN Artwork Rebrand and Avatars: Vantage Design Works (Vanessa Jones)  Website: https://www.vantagedesignworks.com/ Instagram: https://www.instagram.com/vantagedesignworks?igsh=aHRuOW93dmxuOG9m&utm_source=qr Original Artwork Concept: Olivia Pawlowski

    27 min

  8. FEB 26 ·  BONUS

    100: Does Intermittent Fasting Actually Work in 2026?

    This week on Tasty Tip, we break down three new health stories:  • What new research says about intermittent fasting and metabolic health  • Why early-onset colon cancer rates are rising  • Whether caffeine intake may reduce dementia risk  Send us a (voice ) message with this link, we would love to hear from you. Standard message rates may apply. Support the show Production and Content: Edward Delesky, MD, DABOM & Nicole Aruffo, RN Artwork Rebrand and Avatars: Vantage Design Works (Vanessa Jones)  Website: https://www.vantagedesignworks.com/ Instagram: https://www.instagram.com/vantagedesignworks?igsh=aHRuOW93dmxuOG9m&utm_source=qr Original Artwork Concept: Olivia Pawlowski

    23 min
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5
out of 5
17 Ratings

About

Ever leave the doctor’s office more confused than when you walked in? Your Checkup: Health Conversations for Motivated Patients is your health ally in a world full of fast appointments and even faster Google searches. Each week, a board certified family medicine physician and a pediatric nurse sit down to answer the questions your doctor didn’t have time to. From understanding diabetes and depression to navigating obesity, high blood pressure, and everyday wellness—we make complex health topics simple, human, and actually useful. Whether you’re managing a condition, supporting a loved one, or just curious about your body, this podcast helps you get smart about your health without needing a medical degree. Because better understanding leads to better care—and you deserve both.

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