Lab to Market Leadership with Chris Reichhelm

Deep Tech Leaders
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With over 25 years of experience in recruiting leadership teams and boards for advanced science and engineering companies, Chris Reichhelm, CEO of Deep Tech Leaders, offers an insider’s perspective on the pivotal decisions and strategies that shape the success of startups embarking on the lab-to-market journey.This podcast doesn’t just celebrate innovation for its own sake; instead, it highlights what it truly takes to build, scale, and sustain a successful deep tech company. Through conversations with entrepreneurs, investors, executives, and other key players, Chris will explore the management disciplines, cultures, and behaviours essential for commercialising and scaling deep tech innovations. Each episode will aim to unravel the complexities behind turning rich, research-intensive IP into commercially viable products across various sectors like computing, biotech, materials science, and more.'Lab to Market Leadership' is for those who are ready to learn from past mistakes and successes to better navigate the path from innovation to market. Whether you're an entrepreneur, an investor, or simply a deep tech enthusiast, this podcast offers valuable lessons and insights to enhance your understanding and approach to building groundbreaking companies that aim to solve the world's biggest problems and improve our way of life.  Learn more about Lab to Market Leadership: www.deeptechleaders.comFollow us on LinkedIn: www.linkedin.com/company/deeptechleadersPodcast Production by Beauxhaus

  1. Why 55% of Deep Tech Companies Fail: The Communication Problem No One Talks About | Hailey Eustace

    JAN 27

    Why 55% of Deep Tech Companies Fail: The Communication Problem No One Talks About | Hailey Eustace

    Why do 55% of Deep Tech companies fail within five years? Hailey Eustace, founder of Commplicated, argues the answer isn't bad technology - it's bad communication. Product-market fit failures? That's a listening and messaging problem. Can't raise capital? Your story isn't resonating. Struggling to win customers? Trust breakdown. Can't build the right culture? Your messages aren't landing. Hailey's unique background as an analyst at Texas's $500M Deep Tech fund before founding the UK's leading Deep Tech comms agency gives her rare insight into why brilliant founders lose millions because they can't explain what they're doing. She's also an active angel investor, Venture Scout at Ada Ventures, and mentor at Founders (Cambridge) and Deeptech Labs. She reveals the difference between American founders (20%+ budget to comms) and Europeans (resistant to investing), why 'explain it like I'm 5' fails for Deep Tech, and how to develop a core message that works for investors, customers, and your team simultaneously. Her starting point: Define your one thing for 2026. What single message do you want everyone to know? Build from there. This episode challenges the assumption that communications is fluffy. It's strategy. It's product. It's everything. And getting it right could be the difference between the 55% that fails and the 45% that survives. Essential for Deep Tech founders struggling to translate science into business success. Let us know what you think... Learn more about Lab to Market Leadership: https://www.deeptechleaders.com Follow us on LinkedIn: https://www.linkedin.com/company/deeptechleaders Podcast Production: Beauxhaus

    55 min
  2. Manufacturing the Future in Space: Semiconductors, Sovereignty, and Ridiculously Audacious Goals | Josh Western

    11/19/2025

    Manufacturing the Future in Space: Semiconductors, Sovereignty, and Ridiculously Audacious Goals | Josh Western

    What's the value of a ridiculously audacious goal if you never reach it? Josh Western, CEO of Space Forge, argues the question misses the point - because the innovations accelerated along the journey often matter more than the destination itself. Space Forge manufactures advanced semiconductor substrates in microgravity conditions, returns them via reusable satellites, then grows them terrestrially using a ‘sourdough starter’ approach. It's technically audacious, operationally complex, and solves a critical problem: producing higher-purity compound semiconductors for AI, EVs, 5G, and energy infrastructure without Earth's gravitational constraints. Josh reveals why Space Forge could be five different startups (in-space manufacturing, reentry vehicles, heat shields, landing software, crystal growth), but integration creates the real multiplier. He explains the regulatory nightmare of manufacturing in international waters, why payload economics now matter more than launch costs, and how recruiting for passion beats technical pedigree when no one has ‘10 years experience making semiconductors in space.’ His North Star: making space manufacturing so ubiquitous and boring that people don't realise the chip in their kettle came from orbit. Until then, every innovation along the journey - from sovereign supply chain contributions to regulatory frameworks - creates substantial value independent of the ultimate goal. Essential listening for Deep Tech founders navigating vertical integration, novel regulatory challenges, and the tension between moonshot ambitions and incremental Let us know what you think... Learn more about Lab to Market Leadership: https://www.deeptechleaders.com Follow us on LinkedIn: https://www.linkedin.com/company/deeptechleaders Podcast Production: Beauxhaus

    1h 4m
  3. Building Useful Quantum Computers: Constraints, Customers, and the Two Religions of Quantum | Richard Murray

    11/04/2025

    Building Useful Quantum Computers: Constraints, Customers, and the Two Religions of Quantum | Richard Murray

    What happens when quantum computing startups can’t wait 15 years for fault tolerance?  Richard Murray, co-founder and CEO of Orca Computing, reveals how his team chose commercial usefulness over technical idealism - and why that decision drives everything from recruitment to product development. Operating from a University of Oxford spinout with limited resources compared to Google or IBM, Orca faced a choice: follow the same path but years behind and millions of pounds short, or constrain themselves differently. They chose constraints. Starting with just £1.5 million forced creative decisions - building quantum computers with one light source instead of dozens - that ultimately benefited customers through more practical, deployable systems. Richard describes the ‘two religions’ of quantum computing: those pursuing billion-pound fault-tolerant systems versus those focused on immediate commercial value. His team deliberately chose the latter, applying quantum to generative AI with measurable results: reduced GPU requirements, lower energy consumption, and potentially more creative AI models capable of generating results beyond training data. The conversation explores operational realities most quantum companies avoid discussing: the talent gap when no industry exists to recruit from, the cultural shock when physicists encounter commercial constraints, and why ‘comfortable with ambiguity’ matters more than technical brilliance. Richard argues that customers don’t know what they want from quantum - and neither do most vendors - making the shift from vague promises to specific value propositions the defining challenge of the next phase. His most provocative insight: Goldman Sachs apparently defines ‘quantum advantage’ not as an academic milestone but as when a company invests straight off their balance sheet because they can define the business return. That’s the real test. Essential listening for Deep Tech founders, investors, and anyone navigating the trade-offs between breakthrough innovation and commercial survival. Let us know what you think... Learn more about Lab to Market Leadership: https://www.deeptechleaders.com Follow us on LinkedIn: https://www.linkedin.com/company/deeptechleaders Podcast Production: Beauxhaus

    1h 5m
  4. Deep Tech Venture Building: Out The Back Ventures’ Blueprint for University Spinout Success

    09/16/2025

    Deep Tech Venture Building: Out The Back Ventures’ Blueprint for University Spinout Success

    What if early-stage Deep Tech investing could be completely reimagined? Keong Chan, Managing Director of Out The Back Ventures, has spent five years building one of the most unique investment approaches in the industry - operating from Perth, Australia, whilst building relationships with leading universities and national laboratories across four continents. Rather than waiting for deals to come to them, Out The Back Ventures proactively identifies breakthrough research and helps incorporate it into companies from the earliest stages. This conversation explores their syndicated investment model, the hidden innovation opportunities in nuclear technology, and why the future of computing will require fundamental shifts beyond silicon CMOS. Keong reveals how naive questioning, startup-level energy, and genuine relationship building can unlock opportunities that traditional VCs miss, from Oak Ridge National Lab to Oxford University. Essential listening for Deep Tech investors, university technology transfer officers, and anyone interested in how breakthrough research becomes world-changing companies. Let us know what you think... Learn more about Lab to Market Leadership: https://www.deeptechleaders.com Follow us on LinkedIn: https://www.linkedin.com/company/deeptechleaders Podcast Production: Beauxhaus

    1h 3m
  5. Why Deep Tech Unicorns Fail: Lessons from Lilium and Arrival’s Billion-Dollar Mistakes | James Arnold

    09/02/2025

    Why Deep Tech Unicorns Fail: Lessons from Lilium and Arrival’s Billion-Dollar Mistakes | James Arnold

    What can we learn from the collapse of two billion-dollar Deep Tech unicorns? James Arnold held senior strategy and operations roles at both Lilium and Arrival - European companies that raised over a billion dollars each, employed thousands of engineers, and still ended in insolvency. This conversation reveals the hidden pitfalls that destroy Deep Tech companies: why rapid team growth kills startup agility, how too much capital corrupts decision-making, and why applying software ‘blitzscaling’ to hardware development creates catastrophic risks. James provides insider insights into what actually went wrong at companies that had everything going for them - brilliant technology, massive funding, and world-class talent. Essential listening for Deep Tech founders, investors, and anyone who wants to understand why breakthrough technology and vast resources aren’t enough to guarantee success in the lab-to-market journey. Key Topics Covered: - Why blitzscaling from software doesn’t work for Deep Tech hardware companies - The hidden dangers of rapid team growth in complex engineering projects - How vertical integration multiplies complexity and resource requirements - The critical difference between proving you’re ‘not crazy’ vs building for investors - Why scale models in aerospace don’t teach you about real engineering problems - How too much capital can affect decision-making and resource allocation - The importance of focus when developing multiple breakthrough technologies - Finding revenue streams before your moonshot product is ready - Leadership challenges in maintaining stakeholder confidence during long development cycles. Let us know what you think... Learn more about Lab to Market Leadership: https://www.deeptechleaders.com Follow us on LinkedIn: https://www.linkedin.com/company/deeptechleaders Podcast Production: Beauxhaus

    1h 13m
  6. Deep Tech Spinouts: Inside Albion Ventures' Decade-Long Partnership with UCL | Dave Grimm

    08/05/2025

    Deep Tech Spinouts: Inside Albion Ventures' Decade-Long Partnership with UCL | Dave Grimm

    Why do so few university spinouts make it from lab to market? Dave Grimm, Partner at Albion Ventures, has spent a decade answering this question through a groundbreaking partnership with University College London that's transformed how academic innovations become successful companies. This conversation reveals the blueprint for successful university spinouts: embedding VCs within academic ecosystems, prioritising pace over perfection, and creating standardised processes that work for founders and institutions alike. Dave shares insights from successful spinouts like Phasecraft and Oriole Networks, plus his vision for solving the UK's Deep Tech scale-up challenge through government procurement and ‘unretiring’ successful entrepreneurs. Essential listening for anyone involved in university technology transfer, Deep Tech investing, or scaling academic innovations into market-changing companies. Let us know what you think... Learn more about Lab to Market Leadership: https://www.deeptechleaders.com Follow us on LinkedIn: https://www.linkedin.com/company/deeptechleaders Podcast Production: Beauxhaus

    46 min
  7. Quantum Computing Scale-Up: How Universal Quantum is Building Million-Qubit Systems | Dr Sebastian Weidt

    07/01/2025

    Quantum Computing Scale-Up: How Universal Quantum is Building Million-Qubit Systems | Dr Sebastian Weidt

    What does it take to build million-qubit quantum computers - machines that could fundamentally change how we solve the world's most complex problems? Dr Sebastian Weidt, co-founder and CEO of Universal Quantum, shares the extraordinary journey from asking an audacious research question in 2017 to building one of the world's leading quantum computing companies. This conversation reveals the unique challenges of scaling breakthrough technology that operates on entirely different principles from conventional computing. Seb explores why moving from academia to commerce became essential for quantum progress, how to engage customers for technology that doesn't yet exist, and the importance of building supportive culture during long-term, high-risk R&D. With quantum computing potentially 5-10 years away from delivering transformative applications, this episode offers key insights on managing expectations and maintaining momentum during the ultimate Deep Tech journey. Essential listening for Deep Tech Leaders, quantum computing enthusiasts, and anyone fascinated by how impossible engineering challenges become a commercial reality. Watch the video on our YouTube channel. Let us know what you think... Learn more about Lab to Market Leadership: https://www.deeptechleaders.com Follow us on LinkedIn: https://www.linkedin.com/company/deeptechleaders Podcast Production: Beauxhaus

    1h 6m
  8. Challenging Deep Tech Norms: Adopting Lean Principles from Lab to Market | Mark Bjornsgaard

    06/17/2025

    Challenging Deep Tech Norms: Adopting Lean Principles from Lab to Market | Mark Bjornsgaard

    In this captivating episode of Lab to Market Leadership, Chris Reichhelm speaks with Mark Bjornsgaard, the visionary founder and CEO of System Two Group. With a track record of eight successful exits - notably the £200 million sale of Deep Green Technologies to Octopus Energy - Mark brings a powerful, often counterintuitive, perspective on building businesses, especially in the Deep Tech sector.  Mark challenges the conventional wisdom of ‘build-measure-learn,’ arguing passionately for a hypothesis-first approach. He explores why the most valuable skill for an entrepreneur is the ability to ruthlessly ‘kill’ ideas that lack market validation, even if they're technologically brilliant. The conversation explores the psychological barriers to effective innovation, the crucial difference between a solution and a testable assumption, and how genuine behavioural insights drive adoption.  Discover how System Two Group has consistently applied these disciplined methods to achieve remarkable success across diverse industries. This episode is essential listening for Deep Tech founders, corporate innovators, and anyone seeking a more effective, less wasteful path from lab to market. Let us know what you think... Learn more about Lab to Market Leadership: https://www.deeptechleaders.com Follow us on LinkedIn: https://www.linkedin.com/company/deeptechleaders Podcast Production: Beauxhaus

    59 min
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About

With over 25 years of experience in recruiting leadership teams and boards for advanced science and engineering companies, Chris Reichhelm, CEO of Deep Tech Leaders, offers an insider’s perspective on the pivotal decisions and strategies that shape the success of startups embarking on the lab-to-market journey.This podcast doesn’t just celebrate innovation for its own sake; instead, it highlights what it truly takes to build, scale, and sustain a successful deep tech company. Through conversations with entrepreneurs, investors, executives, and other key players, Chris will explore the management disciplines, cultures, and behaviours essential for commercialising and scaling deep tech innovations. Each episode will aim to unravel the complexities behind turning rich, research-intensive IP into commercially viable products across various sectors like computing, biotech, materials science, and more.'Lab to Market Leadership' is for those who are ready to learn from past mistakes and successes to better navigate the path from innovation to market. Whether you're an entrepreneur, an investor, or simply a deep tech enthusiast, this podcast offers valuable lessons and insights to enhance your understanding and approach to building groundbreaking companies that aim to solve the world's biggest problems and improve our way of life.  Learn more about Lab to Market Leadership: www.deeptechleaders.comFollow us on LinkedIn: www.linkedin.com/company/deeptechleadersPodcast Production by Beauxhaus

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