Bloody Minded

Bloody Minded Crew
  • 5.0 (3)
  • MEDICINE
  • UPDATED WEEKLY

Baffled by blood? Confused by coags? Traumatised by TTP? Planning on quitting medical school because you've just finished haem block? Join the fellows of the Bloody Minded Crew as they tour the world of haematology one topic at at a time while procrastinating from their day jobs.  Your time is precious, so to maximise your return we look at each topic at a variety of levels so you can tailor your learning. Check out more at www.bloodyminded.com.au

  1. 5H AGO

    Episode 78 - All The Colours Of The Marrow | Overview of Myeloid Disorders

    What’s a CHIP and why is it so delicious? Why do we still abbreviate myeodysplastic neoplasm to MDS? How did Bashar get his hands on the Necronomicon? These are questions that every budding haematologist asks themselves at some point and we will answer at least some of them here! Join us today for a birds-eye overview of the myeloid family of disorders before we dig into them more over the coming weeks.  TIMESTAMPS 0:57 - Does anyone know a good priest?   3:17 - Myeloid conditions in bucket form   5:30 - Acute vs chronic in haematological diseases   7:35 - Myeloid precursor lesions   10:33 - Myeloproliferative neoplasms   15:23 - Myelodysplastic syndromes   18:50 - MDS/MPN Overlap Syndromes   22:29 - Mastocytosis   26:02 - Acute myeloid leukaemia   28:23 - (Acute promyelocytic leukaemia)   29:36 - Histiocytic/dendritic cell disorders   31:14 - Take Home Messages Support the show Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

    33 min

  2. 6D AGO

    Episode 77 - The Factory Must Grow | Myelopoiesis

    Hi-ho, Hi-ho, it's off the myeloid factory we go. Grab your fastest belt, a spare inserter and all the iron plates you can get your hands on as the Bloody Minded Crew embark on their nerdiest references yet and learn all about the basic science behind myelopoiesis. You’d better hop on a train, because the only main bus here goes straight from the marrow out to the periphery carrying all sorts of myeloid cells. And some blue circuits.  0:52 - New year same us 2:44 - Season overview: myeloid time, baby! 5:15 - What is the myeloid compartment? 7:29 - Myelopoiesis 12:49 - Stem cell destiny... does free will exist? 14:28 - The myeloid progenitor 16:30 - Red cells and platelets 17:46 - White cell maturation 19:34 - Hormonal control of myelopoiesis 21:25 - Historical diversion into GCSF 23:19 - Clinical use of stimulating factors 26:39 - GCSF Bone Pain 28:15 - Emergency Myelopoiesis 30:08 - Wrap Up Support the show Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

    32 min

  3. JAN 27

    Episode 76 - On the Wards: A Practical Guide to Anticoagulants | Part 2 (Oral Anticoagulants)

    So you’ve been asked to start a DOAC? How is that different from a NOAC? Is there a difference? Which one should you start? Is warfarin a WOAC? How do I initiate these drugs? Why is the dose weird at the beginning? Do I need to check my dose is appropriate?  If oral anticoagulation has you discombobulated you are in the right place!! In part II on the practical management of anticoagulation we are here to clarify all your questions on the most common types of oral anticoagulation you will come across as a junior doctor on the wards. Timestamps 1:44 - Part I Recap and Part II Introduction 3:44 - History of Warfarin 8:37 - Mechanism of Warfarin 13:01 - Monitoring Warfarin 16:52 - Why Warfarin? and warfarin tips 21:40 - Warfarin reversal 31:05 - Warfarin Skin Necrosis & Drug Interactions 36:08 - Warfarin in Special Circumstances 40:25 - DOACs Intro 41:12 - Dabigatran 48:25 - Anti-Xa Agents (Rivaroxaban / Apixaban) 52:38 - Anti-Xa Monitoring (or not) 59:28 - DOACS - Special Circumstances 1:05:58 - Wrapup Support the show Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

    1h 7m

  4. JAN 20

    Episode 75 - On the Wards: A Practical Guide to Anticoagulants | Part 1 (Basic Injectables)

    Does my blood look fat in this? Does the idea of heparin being a fraction make you wish you listened harder in maths? What is unfractionated heparin? Why are haematologists so judgmental and prefer their anticoagulation low molecular weight? Why does haematology frown when you use the term “blood thinners” ?!?! If injectable or parenteral anticoagulation feels confusing you have come to the right place! Today we look at unfractionated heparin and low molecular weight heparin,  practical things to think about and how to manage these drugs safely on the wards and beyond  NB We’re going to leave the advanced injectables like Fonda/Danaparoid/Bivalirudin to a dedicated alternative, probably HITTS themed episode if you’re looking for these drugs Support the show Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

    1h 4m

  5. 12/23/2025

    Episode 74 - Christmas Disease | A Bonus Beginners Bonanza on Haemophilia B

    Twas the night before Christmas, and all through the house, not a creature was stirring, particularly not a missing coagulation factor. Welcome to a very special present all wrapped and delivered by Santa and his Christmas elves and stuffed in your podcast queue in time to drive off for the holidays. Join Cale, a very dusty Bashar, Nick and Santa as we learn a little bit about Christmas Disease. We swear his jacket was that colour before we messed with his haemostatic pathways… CONTENT WARNING: Singing TIMESTAMPS 00:55 - Pure unbridled musical talent  03:34 - Intro to Christmas Disease/Haemophilia B 04:58 - History of Haemophilia B 14:01 - Presentation of Haemophilia B 18:25 - Haemophilia B Leyden 22:49 - Coagulation studies in Haemophilia B 26:20 - Treating Haemophilia B 28:12 - Where does factor replacement come from? 31:57 - Inhibitors 33:48 - Gene therapy 37:27 - Take home messages Support the show Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

    40 min

  6. 12/16/2025

    Episode 73 - What A Headache | CVST and Antithrombin Deficiency with Dr Caroline Dix

    We’ve had one difficult coagulation topic yes, but what about second difficult coagulation topic? We are joined by the fantastic Dr Caroline Dix today to take us through not one but TWO challenging scenarios in thrombosis. First we’ll be revisiting Cerebral Venous Sinus Thrombosis but this time with someone who knows what they are doing. After that we’ll cover anticoagulating people when some very fundamental parts of the system are broken - the management of antithrombin deficiency. This episode wraps up our journey through clots… for now.  Timestamps: 2:08 - Introducing Dr Caroline Dix 8:03 - CVST - Risks 11:15 - CVST - Clinical 18:08 - CVST - Duration 21:05 - Antithrombin Deficiency 25:12 - Antithrombin Deficiency - Diagnosis 29:43 - Antithrombin Deficiency - Management 37:34 - Wrapup Support the show Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

    42 min

  7. 12/09/2025

    Episode 72 - How low can you go? | Thrombosis & Thrombocytopenia with Dr Sara Ng

    Sometimes something comes along that puts a chill down the spine of every doctor. Any conversation that starts with "Oh hey do you remember that patient you saw...?". Mystery meat day in the cafeteria. Dealing with hospital executives. For these times in life you need a guide. Today we'll be covering one of those spine-chilling clinical scenarios with our very apt guide consultant haematologist Dr Sara Ng. Over forty minutes Sara will un-chill your spine with her practical approach to managing thrombosis when there just aren't that many platelets to go around, as well as talking about conditions where clots and thrombocytopenia are intimately linked. Timestamps:  2:11 - Introducing Dr Sara Ng 7:18 - Case 1: Acute PE and Thrombocytopenia 14:55 - Case 1.5: Subacute PE and Thrombocytopenia 18:20 - Case 2: Line Thrombus during Chemotherapy 22:09 - Thrombosis in ITP 26:15 - Oh no a STEMI 27:44 - Two sides of the same coin 31:58 - How 2 4T Score - HITS 35:15 - Other PF4 Antibodies 38:33 - Wrap up & Takehomes Support the show Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

    42 min

  8. 12/02/2025

    Episode 71 - Clotting For Good | In The Lab: Thrombophilia Testing II

    Come one come all to see the thinnest extended reference in the universe. Draped over not one but TWO episodes, the Bloody Minded Crew continue to make vaguely topical references to popular recent films. Look - we go outside and experience the full gamut of popular culture. Oh and we finish up our discussion of thrombophilia testing in the lab - looking this week at activated protein C resistance testing, molecular Factor V Leiden assessment and Prothrombin gene mutations. TIMESTAMPS 1:06 - Pay no attention to the man behind the curtain 3:10 - Activated Protein C resistance testing 10:27 - Testing in Australia for APCR 17:17 - FvL Testing 18:51 - PCR - Polymerase Chain Reactions 22:52 - Melt curve analysis 27:39 - Prothrombin G20210A Testing 28:44 - Take Home Messages Support the show Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

    31 min
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About

Baffled by blood? Confused by coags? Traumatised by TTP? Planning on quitting medical school because you've just finished haem block? Join the fellows of the Bloody Minded Crew as they tour the world of haematology one topic at at a time while procrastinating from their day jobs.  Your time is precious, so to maximise your return we look at each topic at a variety of levels so you can tailor your learning. Check out more at www.bloodyminded.com.au

Information

  • Creator
    Bloody Minded Crew
  • Years Active
    2024 - 2026
  • Episodes
    79
  • Rating
    Explicit
  • Copyright
    © 2026 Bloody Minded
  • Show Website
    Bloody Minded

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