In this episode of The Genetic Coach Podcast, we explore the powerful but often overlooked relationship between hormones, genetics, and injury risk in athletes. While hormones are frequently discussed in the context of reproduction, this conversation shifts the focus to how steroid hormones influence muscle strength, connective tissue integrity, bone resilience, recovery, and long-term performance in both female and male athletes. Hosted by Di White, this episode features 3X4 Genetics expert Marina Shanafelt, a certified nutrition specialist and nutrigenomics mentor, who breaks down how estrogen, progesterone, testosterone, DHEA, and cortisol interact with training load, stress, and energy availability to shape injury vulnerability across different life stages. Through real-world case studies, Marina explains how genetic insights can reveal hidden risks related to stress response, hormone metabolism, inflammation, bone health, and tissue repair, allowing athletes and clinicians to move from generalized advice to targeted, high-impact interventions. Whether you are a developing athlete, elite performer, coach, or clinician, this episode provides practical, science-backed insights into how understanding hormonal balance through a genetic lens can support smarter training, better recovery, and long-term athletic resilience. Key talking points: The role of steroid hormones in muscle, tendon, ligament, and bone health How hormonal shifts across puberty, menstrual cycles, and aging influence injury risk Differences in injury patterns between female and male athletes The impact of low energy availability and chronic stress on hormone balance and tissue resilience How genetics reveal individual vulnerabilities in hormone metabolism and stress response Case studies showing how DNA-guided nutrition and training adjustments reduce injury risk Using genetic insights to personalize recovery, fueling, and long-term performance strategies