What the AI?!

Upstart

"What the AI?!" is your weekly guide to the world of artificial intelligence. Industry veterans Jeff Keltner and Annie Delgado break down the latest AI developments, focusing on their impact on business and finance. We decode complex concepts into actionable insights for executives and leaders, keeping you informed and ahead in the AI revolution. Join us as we demystify the technology shaping our future! Brought to you by Upstart. 

  1. FEB 9

    AI in the Wild: Wins, Risks, and Weirdness

    AI is proving it can help in high-stakes situations. It is also proving it can quietly weaken human skills, destabilize organizations, and wander into very strange territory. In Episode 64 of What the AI?!, Jeff Keltner and Annie Delgado start with a landmark Swedish study showing AI-assisted mammography catches breast cancers earlier and reduces radiologist workload. Then they pause on the uncomfortable follow-up: a separate study showing experienced doctors became worse at cancer detection after just three months of relying on AI. The lesson is not “do not use AI.” It is “deploy it without losing your human backup plan.” From there, the episode moves into Google’s Project Genie, the first consumer-facing world model that lets you explore a generated 3D environment for about 60 seconds. Jeff explains why world models matter even if you never want to live inside one, while Annie remains healthily skeptical of the sci-fi future being sold. They then break down OpenAI Frontier, a new enterprise platform designed to let AI agents work across your company’s data and tools, and why this has traditional SaaS companies watching their stock prices drop.  Anthropic publicly commits to keeping Claude ad-free, while OpenAI prepares to test ads in ChatGPT. And finally, Jeff and Annie react to Moltbook, a social network where autonomous bots debate consciousness on a platform security researchers are calling a nightmare. This episode helps you understand where AI genuinely adds value today, where it quietly introduces new risk, and how to avoid mistaking impressive demos for systems you can actually trust.

    30 min
  2. JAN 20

    When AI Starts Buying, Building, and Acting for You

    AI is done just answering questions. Now it wants to do things for you. In Episode 61, Jeff Keltner and Annie Delgado dig into the moment AI shifts from assistant to actor — buying things, managing files, shaping infrastructure, and quietly changing who actually controls the customer relationship.  They start with Google’s Universal Commerce Protocol, an open standard that lets AI agents handle checkout with Shopify, Walmart, and Visa. Which raises a very agentic question: when an AI buys for you… who owns the button? And who owns you? From there, things get spicy. Apple quietly bets on Google’s Gemini to power Siri. Anthropic cuts off Elon Musk’s xAI from Claude while rolling out Claude Cowork. And suddenly everyone is drawing lines around IP, access, and who gets to plug into what. Zooming out, Jeff and Annie look at the physical reality behind all this “AI magic”: Meta and Microsoft taking very different paths to scaling AI — one brute-forcing power, the other chasing trust, permission, and community buy-in. Quick hits keep the fun coming: programmable gene insertion, Gemini’s new “personal intelligence” mode, ChatGPT Translate, and a curveball closer — Matthew McConaughey trademarking himself as a new way to think about consent in the age of generative AI. This episode isn’t about hype. It’s about where the power is actually moving — and what happens when AI stops asking and starts acting. 🔍 In this episode, you’ll learn: Who really controls commerce when AI agents handle checkoutWhy Apple handing Siri to Gemini is a bigger signal than it soundsHow Anthropic is enforcing boundaries in the AI arms raceWhy infrastructure, power, and permission are becoming the real moats How consent, likeness, and ownership get weird — fast — in the AI era

    30 min
  3. JAN 13

    AI Crossed the Line. Now What?

    AI crossed a line this week — from tools that assist to systems that act. Jeff Keltner and Annie Delgado break down the moment where AI stopped feeling experimental and started colliding with the real world. They open with Grok being used to generate non-consensual images — triggering rapid responses from European regulators and U.S. lawmakers — and why this may finally force clarity on platform responsibility. Then comes the productivity shift: Gmail’s new AI inbox tells you what to do instead of what to read, Amazon brings Alexa Plus to the web, and OpenAI launches ChatGPT Health, formalizing how millions already use AI to understand lab results, symptoms, and long-term patterns. They cover Stanford’s SleepFM, which predicts disease risk from a single night of clinical sleep data, and Utah’s quiet experiment letting AI assist with routine prescription renewals. Finally, they zoom out to infrastructure and power. xAI closes a $20B round, LLM Arena becomes benchmarking infrastructure, and Nvidia unveils a blueprint connecting data-center AI to self-driving cars — all while raising the real question: can AI scale fast enough given constraints on power, land, and permitting? This episode isn’t about what AI could do. It’s about what it’s already doing — and what that means for safety, work, health, and the physical world. In this episode, we cover: Why xAI’s Grok triggered global regulatory scrutinyHow Google and Amazon are reshaping daily workflows with AIWhy NVIDIA may be the most powerful AI company of all

    28 min

Ratings & Reviews

5
out of 5
13 Ratings

About

"What the AI?!" is your weekly guide to the world of artificial intelligence. Industry veterans Jeff Keltner and Annie Delgado break down the latest AI developments, focusing on their impact on business and finance. We decode complex concepts into actionable insights for executives and leaders, keeping you informed and ahead in the AI revolution. Join us as we demystify the technology shaping our future! Brought to you by Upstart.