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  1. 1h ago

    Nick Maxwell – Be the Duck on the Pond

    Nick Maxwell got cut by the same football club four years running. Cut at 14. Cut at 15. Cut at 16. Cut at 17, three minutes into a trial, with a snapped vertebra. He made the squad on his fifth attempt and still went undrafted. Four days before Christmas, a phone call changed everything. Nick walks through the voicemail that told him he'd been picked up by Collingwood, the 200-plus games that followed, and how being captain had nothing to do with being the most talented player on the field. It was about the 1%, the tackles, the sprints nobody saw, and showing up for a team that eventually made him captain and led them to a premiership after 20 years without one. Twenty years in sport later, Nick walked away from a stable, structured career to build something of his own. He's honest that the four years since have been harder than anything football put him through, learning IT infrastructure, managing staff, and figuring out leadership without a scoreboard to tell him if he's winning. Stick around for his three life lessons: why resilience is the whole story, why he now buys himself time before reacting to anything, and what two decades observing the Melbourne Storm's most successful leaders taught him about chasing the extra 1%. Want to partner with Life After Launch? Explore sponsorship and partnership opportunities at https://lifeafterlaunchpod.com/partner-with-us Life After Launch is an Aussie Founders Club podcast. 🦘 Aussie Founders Club is a community for founders, operators, and investors navigating the Australian startup ecosystem. What started as an events-first, in-person community has grown into a network of thousands, connecting people building startups with the people who've done it before. Join the conversation and the community at https://aussiefoundersclub.com/ Connect with Megan Luttrell on LinkedIn - https://www.linkedin.com/in/meganluttrell/ 💵 Mayfly Ventures is a venture studio building industry-focused AI and software ventures. Mayfly is an Australian AI venture studio. We work with industry leaders to validate, build, and scale AI ventures, starting with the strategy and commercial foundations most teams skip. Learn more about Mayfly's approach at https://www.mayflyventures.com/ Connect with Geo George on LinkedIn - https://www.linkedin.com/in/contactgeo/ 🤝 Kairos Recruitment is a recruitment company supporting startups and scale-ups across Australia, helping founders find the right people to grow their teams. Led by Megan Luttrell. Learn more at https://www.kairosrecruitment.com.au/ Time Stamps00:00 Cold open: cut 4 times, then 4 voicemails 01:31 Welcome to Life After Launch, introducing Nick Maxwell 03:07 Manure at 12, KFC at 14, and getting cut from the Falcons 4 times 15:15 The Collingwood voicemails, and playing 200+ games 17:20 Not the most talented player: doing the 1%ers and becoming captain 22:13 Leadership styles, the Melbourne Storm, and the "finished product" trap 33:07 Media, an MBA in 18 months, and deciding to leave sport 35:57 Why Eclat, and building a "life MBA" into a workspace 44:04 Building the team, ownership, and trusting people to do their jobs 54:24 The hardest 4 years of his life: building Eclat from scratch 58:56 Life lesson 1: resilience is the whole story 59:54 Life lesson 2: buy yourself time before you react 1:02:41 Life lesson 3: chasing the extra 1%, with lessons from Craig Bellamy 1:09:35 Closing thoughts + outro

    Nick Maxwell – Be the Duck on the Pond

  2. 3d ago

    Vibe coding til he dies

    Lazar Jovanovic didn't go to engineering school. He found a beta tool called GPT Engineer, set himself a challenge to build a new app every week, and filmed the whole thing. Two years later he's Lovable's in-house vibe coder, building load bearing internal tools that engineers tell him used to take a team of twenty. In this episode of In the Blink of AI, Georgie Healy hands him her own website and asks him to roast it live. He does, in about four minutes, and the fixes he gives are ones you can apply to your own site today. From there it gets sharper. Why "explain it like I'm five" is the worst thing you can say to an AI, and the exact script to use instead. Why opening four tabs costs you less than fixing one bad build. Why he thinks almost nobody writes their own code by hand anymore, and why that was never the valuable part of engineering anyway. And when Georgie asks why people blame the tools, he gives the line the whole episode hangs on: it's a vehicle, it's faster than you, and if you won't take the wheel, enjoy the cliff. Plus what's actually left for humans when building gets cheap, the three tools he can't work without, and who he thinks Georgie should book next. Hands on episode. Get a pen. Mentioned in this episode: Deel x BAI_Script 01 - Sep 2026 Deel x BAI_Script 02 - Sep 2026

    Vibe coding til he dies

  3. 5d ago

    The Engineer Who Hasn't Written Code in 9 Months: Jack Rudenko, 10x Labs

    Jack Rudenko hasn't written a line of code himself in nine months. In that time, his team has shipped six or seven products used by millions of people, and he says that gap, between who writes the code and who's actually building, is the whole story of engineering right now. In this episode of Building Tech Teams, James MacDonald sits down with Jack Rudenko, Chief AI Officer at 10x Labs, where he has spent the past two years building an AI-native engineering practice from the ground up. They get into the project everyone called impossible before AI made it a three-month build, why working with AI agents is more exhausting than writing code ever was, and what actually separates an engineer from an artist or a scientist now that the code itself isn't the hard part. It's a hands-on, practitioner's take on what building with AI agents actually looks like day to day, not the conference-keynote version. They cover Jack's own workflow for briefing an AI agent, why he doesn't trust any project's security the moment an API key exists, the "non-engineering builders" quietly out-building agencies, and why he calls Claude Code some of the worst-engineered software he's ever used, and also the tool he loves most. CHAPTERS 0:00 - Cold open: the line that explains why most AI engineering doesn't work 0:31 - Who Jack Rudenko is, and what's ahead in this episode 1:27 - Welcome, meet Jack Rudenko, Chief AI and Technical Strategist at 10x Labs 1:48 - The real bottleneck in AI engineering is human, not technical 3:36 - Why "AI native from scratch" beats bolting AI onto old processes 8:53 - Inside Magus, treating AI skills like versioned software packages 11:20 - 500 skills later, building a curated knowledge base for AI agents 14:56 - The rise of the "non-engineering builder" 17:06 - Why enterprise software is the real mess, not startups 19:32 - The unexpected cost of working with AI, burnout, not laziness 21:24 - Jack's actual workflow, plan mode, research, and acceptance criteria 27:26 - Dark factories, evals, and "religion" versus "engineering" in AI 29:49 - The skill nobody measured, loaded less than half the time 32:52 - Why AST trees beat graph databases for AI code memory 36:07 - From 10X to 50X, two projects AI made possible 41:35 - What team size looks like when one person can do it all 42:53 - Why no project is secure once a key exists 46:44 - Artist, scientist, engineer, what actually makes you one 51:04 - What junior engineers need to learn now 54:45 - Cursor, YC founders, and the rise of the non-engineer builder 59:35 - The addictive, exhausting superpower of building 10X more 1:02:57 - Why "impossible" projects are worth the budget now 1:04:55 - The future of software, giant platforms and a million small ones 1:08:04 - Why consultancies are thriving, for now 1:09:12 - "Claude Code is the worst software ever. I love it." 1:11:22 - Open source, Jack's origin story, and why it built him 1:15:23 - James's takeaway: religion vs engineering, and the challenge to measure your own AI rollout ABOUT THE GUEST Jack Rudenko is Partner and Chief AI Officer at 10x Labs, where he has spent the past two years building the team’s AI-native engineering practice, Magus, from the ground up. He has deep expertise in cloud-native architecture, Go, Kubernetes and complex systems, and has delivered production platforms that would have been considered technically impossible before AI, including a three-system integration project used as a case study on this episode. Jack is also a longtime open-source contributor, including to the Linux kernel.at 10x Labs, where he has spent the past two years building the team’s AI-native engineering practice, Magus, from the ground up. He has deep expertise in cloud-native architecture, Go, Kubernetes and complex systems, and has delivered production platforms that would have been considered technically impossible before AI, including a three-system integration project used as a case study on this episode. Jack is also a longtime open-source contributor, including to the Linux kernel. LINKS Jack Rudenko, 10x Labs · LinkedIn: https://www.linkedin.com/in/erudenko/ James MacDonald, NTP Talent · LinkedIn: linkedin.com/in/jamesmacdonaldau · Site: ntptalent.com.au Hosted by James MacDonald, Managing Director of NTP Talent. --- Building Tech Teams is produced by Day One®, trusted partners in the technology space and the team who helped build Blackbird Ventures' Wild Hearts. Sister shows include First Cheque, Oversubscribed and In The Blink of AI. Episodes are cross-promoted across the network.

    The Engineer Who Hasn't Written Code in 9 Months: Jack Rudenko, 10x Labs

  4. Aug 31

    Shane Chanel - Nothing’s Ever Going to Be as Hard as That Day

    Shane Chanel bet his entire life savings, $20,000, on a four-wheel drive racing app when he was 14. It wasn't his last high-conviction bet. He went on to leave a stockbroking career to build Yondr Money, a digital bank that never became a bank, survived a hostile takeover attempt from his own investor, and is now building Kobble, the infrastructure that lets almost any business launch a financial product in weeks instead of years. He's honest about where the drive comes from: a chip on his shoulder he can't fully explain, a family that worked hard for everything, and a day in 2012 he's never spoken about publicly before this episode, the day his uncle's family was found dead and he became next of kin for his baby niece. It's the reference point, he says, for everything since. Nothing has ever felt as hard. Shane walks through the pain points that pushed him from asset management into building a bank from scratch, why he pulled out of the banking licence process, how a chance conversation with former ANZ CEO Mike Smith became one of his best investors, and how a wall covered in Post-it notes from fellow fintech Founders became Kobble. Stick around for the hardest lesson of all: the hostile takeover attempt from an investor who'd only just come on board, and why Shane now tells every Founder to have the uncomfortable conversations early, before you need them. Find Shane Shane on LinkedIn: https://www.linkedin.com/in/shanechanel/ Kobble AI: https://ai.kobble.net/ Kobble: https://kobble.net/ Yondr: https://www.yondr.money/ Join the Aussie Founders Club The Slack community, the newsletter and everything else live here: https://www.aussiefoundersclub.com Want to partner with Life After Launch? Explore sponsorship and partnership opportunities at https://lifeafterlaunchpod.com/partner-with-us Time Stamps 00:00 Cold open + welcome to Life After Launch, introducing Shane Chanel 02:54 From wanting to be an aeronautical engineer to financial planning and stockbroking 08:35 Identity, the chip on the shoulder, and working twice as hard 16:51 Betting his life savings on a racing app at 14, and the idea for a bank 25:53 Building Yondr, pulling out of the banking licence, and landing Mike Smith as an investor 38:48 The 2012 story: his uncle's family found dead, and the reminder that nothing will ever be this hard 45:27 Acquiring Shouta and building Kobble from a wall of Post-it notes 53:50 Kobble AI: prototyping a financial product in 15 minutes 1:02:09 Life lesson: the hostile takeover attempt, and why you should always do the prenup 1:05:12 Closing thoughts + outro

    Shane Chanel - Nothing’s Ever Going to Be as Hard as That Day

  5. Aug 30

    Trust Over Likability: How Charles Hudson Built a 450-Company Portfolio

    Episode SummaryCharles Hudson of Precursor Ventures has built one of the most ambitious solo GP models in venture capital: around 450 investments over the last decade, with a 14-person team supporting a single investment decision-maker. In this episode of First Cheque, Charles joins Maxine and Cheryl to unpack what it really takes to build and scale a solo GP fund, why he believes partnership dynamics can be one of the biggest risks in venture, and how he thinks about delivering value to hundreds of founders without trying to be everything to everyone. They dive deep into Charles’ philosophy on trust versus likability, why the best investors sometimes need to tell founders things they really don't want to hear, and how brutal honesty can become one of the most valuable forms of founder support. Charles also shares his approach to identifying “underappreciated” founders, why he looks for people who opt into chaos, and what he learned from backing founders who weren't necessarily great employees. Charles reflects on leaving a safe, highly compensated investing job to start Precursor, investing internationally before it was fashionable, why themes can kill returns, and the importance of being early to categories rather than piling into them once everyone else has arrived. Time Stamps00:00 – Intro 03:05 – Charles’ first investment: buying ExxonMobil in high school 06:15 – What exactly is a solo GP? 07:37 – The surprising benefits of having one decision-maker 10:28 – The problem with orphaned portfolio companies 13:04 – Why solo GPs need to be intentional about founder relationships 15:44 – How the “product” of Precursor evolved 18:00 – Building trust, setting expectations, and knowing when to step back 20:32 – Why honest feedback matters more than being liked 23:40 – “It’s you”: giving founders brutally honest feedback 25:52 – Trust is a bank account 27:47 – Likability vs. trustability in venture capital 30:58 – Why Charles backs founders who opt into chaos 33:36 – What makes a great first-time CEO? 36:39 – How Precursor started investing globally 40:08 – Investing internationally and convincing LPs afterwards 41:15 – Why themes can kill returns 44:12 – Finding venture-scale opportunities outside traditional software 45:16 – The challenge of managing 450 investments 47:52 – Being a “surgeon” investor: showing up when it matters most 52:04 – Charles’ biggest leap: leaving Uncork to start Precursor 53:40 – “You pay money to go to work?” 55:00 – Why Charles chose to make going back impossible 56:31 – Outro ResourcesPrecursor Ventures - https://precursorvc.com/ Sponsors:First Cheque is supported by our wonderful sponsors:Deel: Global hiring and payroll can be a headache. Deel brings HR, IT and payroll together in one platform, helping companies including Shopify, Revolut and ElevenLabs scale internationally. Ready to expand your business? Build your global team with Deel at deel.com/dayone. ___ Pear Tree: Pear Tree helps Australian and New Zealand founders build high-performing offshore teams without the agency middleman. As local hiring becomes more expensive and harder to fill, many operators are turning to offshore talent across engineering, development, marketing, accounting and operations at a fraction of local salary costs. The offshore horror stories you hear usually aren’t a talent problem. They’re the result of outsourcing agencies that overcharge clients while underpaying staff. Pear Tree takes a different approach through a direct, transparent model where your team is paid fairly, fully compliant, and focused entirely on your business. As part of the Day One community, you’ll receive a free team audit to identify where offshore talent could move the needle in your business, plus 20% off your first hire. Learn more at http://dayone.fm/peartree First Cheque is part of Day One.Day One helps founders and startup operators make better business decisions more often. To learn more, join our newsletter to be notified of new First Cheque episodes and upcoming shows. Mentioned in this episode: Pear Tree If you're a founder or operator trying to scale, here's the reality — Australian hiring is getting harder, salaries are at record highs, and the talent you need is increasingly out of reach. The best operators are quietly building offshore teams of engineers, marketers, accountants and analysts at a fraction of the cost. Pear Tree does it differently. We headhunt highly skilled talent from the Philippines and South Africa with full transparency on where every dollar goes, so your team is paid fairly and fully focused on your business. As a Day One listener, you’ll receive a free team audit to identify where offshore talent could move the needle in your business, plus 20% off your first hire. Deel x PX_Script 1 Deel x PX_Script 2 This podcast uses the following third-party services for analysis: Podtrac - https://analytics.podtrac.com/privacy-policy-gdrp Spotify Ad Analytics - https://www.spotify.com/us/legal/ad-analytics-privacy-policy/

    Trust Over Likability: How Charles Hudson Built a 450-Company Portfolio

  6. Aug 30

    Patrick Buchan: Australia's first new steel mill in 30 years

    Australia hasn't built a new steel mill in more than 30 years. Greensteel Australia is about to — a $500 million all-electric plant on the old BHP site at Mayfield, producing 600,000 tonnes of rebar a year from the first quarter of 2028. Patrick Buchan, Greensteel's Head of Government Relations, joins James MacDonald on the Danieli technology being built in Italy right now, the policy shift that made onshore steel viable again, why Newcastle beat the rest of the country for the site, and what 200 jobs means for the Hunter. In this episode: The $500 million investment and what it buys — an all-electric mill on Industrial Drive at Mayfield North, the site BHP ran until 1999.Why the technology is the story: an electric arc furnace running at around 1,000 degrees, supplied by Danieli of Italy. "No gas, no flame, no chimneys."600,000 tonnes of rebar a year — the critical input to Australian construction and housing — with a growth path into other steel products.The policy shift: faster approvals, Future Made in Australia incentives, and why both the federal and NSW governments moved.Sovereignty as the argument — oil, steel and microprocessors as the three inputs a country of 28 million can't afford to import.How Greensteel started: owners Meena and Romana Ibrahim couldn't get rebar for their own construction businesses through COVID, so they built a steel company.Why Mayfield — buildings long enough for a 400-metre rolling line, rail, power and roads, and an intergenerational steel skill base.The jobs: 200 direct roles, recruitment opening early 2027, Danieli training included, and no formal-qualification barrier.What's next — a stage two in advanced discussions for another New South Wales site, and a ground-breaking with "a very notable political figure." Patrick Buchan is Head of Government Relations at Greensteel Australia, the company building a $500 million all-electric steel mill at Mayfield in Newcastle — Australia's first new steel plant in more than three decades. Before Greensteel he spent four years on the policy staff of the US Office of the Secretary of Defense at the Pentagon, across the Obama and first Trump administrations. Greensteel opens recruitment for the Newcastle mill in early 2027. Patrick Buchan on LinkedIn: linkedin.com/in/patrick-buchan-56830b124 Chapters 0:00 Cold open 1:03 Welcome to Engineering in the Hunter 1:56 Patrick's path from Canberra to Greensteel 3:24 Four years inside the Pentagon 6:01 How Australian policy made this possible 9:21 The 600,000-tonne rebar plan 10:27 Inside the new steelmaking technology 14:01 The politics behind the comeback 18:43 How Greensteel Australia got started 20:29 Greensteel signs the deal 21:05 Why Mayfield, Newcastle won the site 21:56 Balancing tradition and renewables 23:34 The road to 2028 24:06 200 jobs and an open call for workers 26:38 The $500 million investment, by the numbers 27:19 How Newcastle is already talking about it 28:22 Sovereign manufacturing and sustainability 29:48 Australia's first steel plant in 30 years 31:39 The trend back to trades 32:40 What's next: stage two 35:35 On founders and entrepreneurship 36:57 On risk, reward, and having a crack 38:16 A story about his dad and the cricket 39:45 Wrapping up Engineering in the Hunter is hosted by Melinda Sietsma with NTP Talent founder James MacDonald. James hosts this episode. Learn more at ntptalent.com.au. Engineering in the Hunter is produced by Day One®, trusted partners in the technology space and the team that helped build Blackbird Ventures' Wild Hearts. Sister shows include First Cheque, Oversubscribed and In The Blink of AI. Episodes are cross-promoted across the network.

    Patrick Buchan: Australia's first new steel mill in 30 years

  7. Aug 27

    Elon Musk: Hero to Headcase

    For a decade, Elon Musk was the face of the modern entrepreneur: a self-made billionaire who bet his fortune on impossible ideas and somehow made them work. SpaceX made reusable rockets a reality. Tesla helped turn electric cars into a global phenomenon. He became one of the most admired and influential figures in technology. So what happened? In this episode of In the Blink of AI, Georgie Healy traces Musk’s journey from bullied South African kid and PayPal millionaire to the man behind Tesla, SpaceX, Starlink, X, xAI and more. Along the way, we explore the moments that transformed his public image: the Tesla “funding secured” controversy, his increasingly combative behavior online, his influence over Starlink during the war in Ukraine, his takeover of Twitter, his political rise alongside Donald Trump, and the controversies surrounding Grok. But this isn’t simply a takedown. Using the 4Gs framework, Georgie asks the harder question: Was Elon Musk actually a genius, or was he simply in the right place at the right time? The answer is more complicated than either side might want to admit. Because Musk may genuinely have helped solve some of the hardest engineering problems of our time. But does extraordinary capability excuse harmful behaviour? You be the judge. CHAPTERS 00:00 Elon Musk: From the World’s Most Admired Entrepreneur to the Most Controversial 02:08 Growing Up in South Africa: Bullying, Obsession, and Early Signs of Genius 02:57 Leaving South Africa and Building His First Tech Ventures 04:26 Zip2: Musk’s First Major Exit and the $307 Million Sale 04:38 X.com, PayPal, and the Power Struggle That Ousted Musk 05:26 The PayPal Mafia and the Fortune That Funded Musk’s Next Bets 07:40 SpaceX and Tesla: Betting His Fortune on Impossible Ideas 08:09 Falcon 1’s Historic Launch and SpaceX’s Near-Death Experience 08:50 Tesla’s Rise and the Revolution of Electric Cars 10:28 Peak Elon: SpaceX, Tesla, Neuralink, and the Golden Years 11:06 How Much Did Elon Musk Actually Build? The Founder Debate 12:27 The Iron Man Myth and the People Behind Musk’s Companies 13:26 2018: The Year Elon Musk’s Public Image Changed 13:50 The “Funding Secured” Tweet and Tesla’s SEC Battle 15:10 The Thailand Cave Rescue and the “Pedo Guy” Controversy 15:45 Joe Rogan, Marijuana, and Musk’s Growing Pattern of Controversy 18:18 Starlink in Ukraine: When a Private Company Controls Wartime Infrastructure 19:17 Musk, Crimea, and the Limits of Private Power 20:47 Why Starlink May Be Musk’s Biggest Governance Problem 21:07 Buying Twitter for $44 Billion and Taking Over the Platform 22:00 Mass Layoffs, Free Speech Absolutism, and the Birth of X 23:43 Hate Speech, the Great Replacement Theory, and the Advertiser Exodus 25:13 The Case Against Musk’s Version of Free Speech 27:11 Musk Enters Politics and Becomes Trump’s Biggest Donor 28:02 DOGE, the Controversial Gesture, and Musk’s Growing Political Influence 28:44 Tesla Protests, DOGE’s Promised Savings, and the Fallout 30:58 Musk vs. Trump: From Political Alliance to Public Feud 31:16 xAI and Grok: Musk’s Vision for an “Anti-Woke” AI 32:08 Grok’s Hitler Controversy and the Rise of “Spicy Mode” 33:46 AI Safety, Non-Consensual Images, and the Cost of Unrestricted AI 35:00 The Expanding Musk Empire: SpaceX, Starlink, X, xAI, Tesla, and More 36:28 The 4 Gs: Is Elon Musk a Grown-Up, Genius, or Something Else? 36:49 Why Musk Fails the “Grown-Up” and “Gravitas” Tests 39:00 Genius vs. Accountability: What Musk Actually Changed 40:00 The Final Verdict: Genius Without a Hall Pass

    Elon Musk: Hero to Headcase

  8. Aug 26

    The Psychedelic Resurgence: From Counterculture to Clinical Breakthrough with Dr Michael Winlo

    One in three people will experience a mental health disorder in their lifetime, PTSD went more than 20 years without a new approved treatment, and spending keeps rising while outcomes keep getting worse. Against that backdrop, Australia has become the first country in the world where psychiatrists can prescribe MDMA and psilocybin. In this episode, host Emily Casey sits down with Dr Michael Winlo, Chief Scientific Officer at Emyria, the company behind the Empax network of psychedelic-assisted therapy clinics. Michael trained as a doctor, spent four years in Palantir's healthcare team in Silicon Valley, then returned to Perth to run a clinical trial site — an experience that convinced him care delivery and evidence generation belong together, and led to Emyria. Michael explains how the two legal treatments actually work. MDMA floods the brain with serotonin and oxytocin, quietens an overactive amygdala and lets patients with post-traumatic stress disorder work through trauma in therapy without being overwhelmed by fear or shame. Psilocybin quietens the default mode network behind rumination and negative self-talk — Michael's metaphor is shaking up a snow globe and letting the snow settle into new patterns — and both drugs open a roughly seven-day window of heightened neuroplasticity that therapy can use. The pair trace the strange history that got us here: MDMA first synthesised by Merck in 1912, psychedelics on the cover of psychiatry journals in the 1960s, roughly 500,000 people given MDMA in therapeutic settings before the war on drugs shut the research down. Charitable funding through MAPS kept the science alive, and the resulting phase 2 and 3 trials left the TGA unable to maintain that these drugs had no therapeutic value — leading to the world-first rescheduling in 2023. Michael then walks through what treatment at an Empax clinic involves: careful screening, a two-therapist dyad that stays with the patient for the whole journey, six-to-eight-hour dosing days in a low-stimulus room, and integration sessions that turn insights into durable habits. Emyria has now treated more than 100 patients, with rapid improvement that appears durable for most — results that have brought funders like Medibank and the Department of Veterans' Affairs on board. The conversation closes on what it will take to make this mainstream: health-economic evidence for a treatment that costs around $10,000 a dosing cycle, the watershed of a first FDA approval, more sensible regulation of who can deliver therapy, and the infrastructure and training to meet demand. Michael argues psychedelics are still under-hyped — used today as a last resort when they may do the most good earlier in a patient's journey — and leaves clinicians with one message: learn with your patients. GuestDr Michael Winlo is Chief Scientific Officer at Emyria, the ASX-listed company behind the Empax network of psychedelic-assisted therapy clinics, treating post-traumatic stress disorder and treatment-resistant depression under the TGA's Authorised Prescriber Scheme. Trained as a medical doctor, he spent four years in Palantir's healthcare team in Silicon Valley and led Perth's Linear Clinical Research before joining Emyria to build a model of care that treats patients and generates evidence at the same time. Chapters00:00 Psychedelics return to healthcare 00:57 What Emyria and the Empax clinics do 02:08 From medicine to Palantir and back to Perth 08:32 Why mental health care is falling behind 12:37 What psychedelics actually are 13:55 How MDMA-assisted therapy works 17:44 Psilocybin and the default mode network 21:05 A century of history: from Merck to the war on drugs 24:18 The revival: MAPS, new trials and Australia's rescheduling 27:17 Why psychiatry innovates slowly 29:47 Inside treatment: screening, dosing days and integration 33:33 The data so far: 100+ patients, Medibank and the DVA 35:18 Ketamine and the coming wave of new treatments 36:47 FDA approval and the funding shift 43:30 Emyria's ten-year vision 45:47 Bottlenecks: training, regulation and infrastructure 47:31 Psychedelic therapy in 2035 49:09 Rapid fire: hype, books and one message for clinicians Links and resourcesEmyria: https://emyria.com/ Empax Centre: https://empaxcentre.com/ TGA — re-scheduling of psilocybin and MDMA, questions and answers: https://www.tga.gov.au/resources/publication/scheduling-decisions-final/notice-final-decision-amend-or-not-amend-current-poisons-standard-june-2022-acms-38-psilocybine-and-mdma/re-scheduling-psilocybin-and-mdma-poisons-standard-questions-and-answers MAPS (Multidisciplinary Association for Psychedelic Studies): https://maps.org/ COMPASS Pathways: https://compasspathway.com/ The Beginning of Infinity by David Deutsch: https://en.wikipedia.org/wiki/The_Beginning_of_Infinity Moonshots with Peter Diamandis: https://www.diamandis.com/podcast About the hostEmily Casey is the founder of What the Health and host of the show, making major developments in health technology and innovation easier to understand. What the Health is brought to you in partnership with Tenmile Ventures. What the Health is part of Day One Network, the podcast and media network from W2D1 Media: https://dayone.fm/

    The Psychedelic Resurgence: From Counterculture to Clinical Breakthrough with Dr Michael Winlo
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    Day One
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  • Years Active
    2024 - 2026
  • Episodes
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