Deep Dive into Reproduction with LIFE by Dr. Pat

LIFE by Dr. Pat
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Deep dive into reproduction and fertility treatment by LIFE by Dr. Pat Clinic and Dr. Patsama Vichinsartvichai

  1. 2d ago

    The malaria pill that sterilized thousand women world wide.

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  2. Aug 11

    Treating uterine fibroid without surgery

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  3. Aug 4

    Creating a human life in a shoe box. Low Cost IVF

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  4. Aug 2

    Your prenatal vitamins may be not sufficient.

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  5. Jul 26

    10 common IVF add-ons; effetive and safe ?

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  6. Jul 20

    3D vaginal ultrasound will help you solve the mystery of ivf failure?

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  7. Jul 20

    Chromosome test on embryos before implantation: 2026 update

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  8. Feb 24

    Restoring Shugoshin 1 to Rescue Cohesion in Aged Human Eggs

    Send us Fan Mail This research identifies why advanced maternal age frequently leads to infertility and pregnancy loss due to chromosome segregation errors in eggs. The study reveals that as oocytes age, they lose pericentromeric transcription and the protein Shugoshin 1 (SGO1), which are essential for protecting the glue that holds sister chromatids together. By using mouse and human oocytes, the scientists discovered that inhibiting these transcriptional processes causes premature sister chromatid separation. While adding specific RNA can help younger eggs, it is insufficient for older ones because SGO1 protein levels are too low. Crucially, the researchers successfully reduced these chromosomal errors by supplementing SGO1 through microinjection. This breakthrough suggests a potential therapeutic strategy to improve the quality of human eggs and increase the success rates of assisted reproduction.

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Deep dive into reproduction and fertility treatment by LIFE by Dr. Pat Clinic and Dr. Patsama Vichinsartvichai

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