Startup and Nation

Meng Fei Shen

Where startup meets government, academia, and global innovation Let’s talk opportunities. Across countries, industries, and sectors. We’re here to breakdown the network siloes to uncover emerging opportunities and ventures across the global startup ecosystem. This podcast is for founders, investors, academics, governments, and anyone who wants to nerd out with us on the creative ways startups can engage with various sectors and markets (and vice versa!).

  1. 07/09/2025

    From Scientist to Startup Founder: Building the Virtual Cell for Drug Discovery | Natalie Ma, Deep Origin

    In this episode of Startup & Nation, we dive deep with Natalie Ma, co-founder and head of business development at Deep Origin. Natalie's journey from environmental science undergraduate to co-founding a startup is a fascinating tale of curiosity-driven transitions. We explore her path through a PhD in synthetic biology, frustrations with the slow application of academic research, and a fortuitous meeting that led her to startups. Natalie explains how Deep Origin aims to build a 'virtual cell' to reduce failures in drug discovery and development, discusses market validation for biotech startups, and elaborates on the importance of industry-academic collaboration. This insightful conversation covers the challenges of translating academic research to practical applications, the nuances of market needs, and the role AI could play in regulatory processes. Tune in to understand the dynamic world of biotech innovation and the human-centric approaches driving it forward. 00:00 Introduction to Natalie Ma and Deep Origin 01:30 Natalie's Journey from Academia to Industry 05:43 Challenges and Insights in Biotech Startups 11:56 Deep Origin's Mission and Innovations 19:33 Balancing Social Impact and Profit 23:44 Cultural and Practical Differences Between Academia and Industry 33:33 The Challenge of Valuing Research 34:39 Practical Problem-Solving in Academia 36:51 Bridging the Gap Between Academia and Industry 37:32 Teaching Open-Ended Questioning 40:35 The Role of AI in Research and Regulation 50:14 How to think about Public-Private Partnerships 53:35 Networking and Overcoming Social Anxiety 59:22 Final Thoughts and Call to Action

    1h 1m
  2. 06/26/2025

    Driving Innovation in Health Tech: Strategies for Successful Research Commercialization | Deanna Angello, Springboard Enterprises

    Join us for an insightful conversation with Deanna, an expert in transforming breakthrough science and technology into market-shaping products and businesses. With over 25 years of experience at Pfizer, Genentech/Roche, Kite/Gilead, and Johnson & Johnson, Deanna has led seven blockbuster products generating $7B+ annually. In this episode, she discusses her unique bench-to-bedside mindset, combining R&D, commercial strategy, and market access. Deanna shares invaluable advice for entrepreneurs in health tech and biotech sectors, focusing on leadership, commercialization, and patient-centric strategies. Learn how she builds trust across ecosystems, drives cross-functional teams, and employs data-driven execution to accelerate growth and improve patient care. 00:00 Introduction to Deanna Angelo 01:10 Deanna's Career Journey 05:00 Falling in Love with the Industry 06:55 Commercialization in Biotech 11:19 Challenges in Research Commercialization 15:40 Common Mistakes by BioTech Startups 20:28 Leadership and Self-Awareness 24:45 Big Pharma and Regulatory Trends 27:36 Longevity and Proactive Healthcare 28:45 Challenges in Biotech Funding and Big Pharma 30:08 Opportunities for Startups in Health Tech 32:47 The Role of AI in Drug Discovery 36:35 Comparing Health Tech Ecosystems: DC, SF, and NY 41:54 Adapting and Learning in a Changing Industry

    47 min
  3. 05/30/2025

    Vietnam’s Startup Sprint: Growth, Young Talent, and Cross-Border Collaboration | Cong-Thang Huynh and Gaku Echizenya

    In this episode of Startup and Nation, I sit down with Huynh Cong-Thang and Gaku Echizenya at the Sushi Tech Conference in Tokyo. Thang co-founded InnoLab Asia and is a key player in Vietnam's growing startup ecosystem, fostering connections between policymakers, startups, and corporations both domestically and internationally. Gaku, a Japanese entrepreneur with over a decade of experience in Ho Chi Minh City, heads Vietnam's largest recruitment service.  We discuss Vietnam's rapid economic growth, new infrastructure developments, and the vibrant startup scene. We also touch on the opportunities and challenges in Vietnam’s market for foreign entrepreneurs and the importance of local partnerships. Tune in to learn more about Vietnam's potential as a center of innovation in Southeast Asia. 00:00 Introduction: Huynh Cong-Thang and Gaku Echizenya 01:32 Conference Insights: Networking and Partnerships 02:47 Gaku's Journey and Perspective on Vietnam 03:38 Thang's Vision for Vietnam's Future 04:58 Challenges and Opportunities in Vietnam's Ecosystem 07:44 Infrastructure Developments and Future Potential 10:45 Building the Startup Ecosystem: Programs and Partnerships 15:45 Success Stories and International Collaborations 17:26 Cultural Challenges and Tips for Foreign Entrepreneurs 17:57 Navigating Daily Life in Vietnam 18:34 Business Ethics: Japan vs. Vietnam 19:31 Advice for Foreign Startups in Vietnam 22:24 Understanding the Vietnamese Market 24:32 Building Partnerships in Vietnam 29:33 Reflections on Sushi Tech Conference

    33 min
  4. 04/29/2025

    Bill Reichert: Building the Venture Capital System of Silicon Valley...and the World

    In this episode of Startup Nation, I interview Bill Reichert, a pioneering figure in Silicon Valley's venture capital ecosystem. Bill shares his journey from founding a software company in the 1980s to establishing Garage Technology Ventures with Guy Kawasaki. Known for coining and popularizing fundamental investment concepts like seed and pre-seed funding, Bill has been instrumental in shaping the modern startup accelerator model and fostering global venture capital accessibility. We discuss the evolution of venture capital, the groundbreaking concept of global VCs, and the rise of seed and pre-seed funding. Now a partner at Pegasus Tech Ventures, Bill elaborates on the innovative 'venture as a service' model that bridges startups with global corporations. We also cover the challenges of corporate partnerships, the significance of open innovation, and the future trends in technology and defense sectors. Bill’s ability to simplify complex concepts is particularly highlighted, making this episode a must-watch for aspiring entrepreneurs and investors. 00:00 Introduction to Bill Reichert and His Impact on Silicon Valley 02:49 Bill's Early Days and First Startup Experience 05:59 Founding Garage Technology Ventures 08:09 The Pegasus Tech Ventures Model 23:12 Startup World Cup: A Global Competition 27:29 Impact of Government Policies on Venture Capital 30:20 Emerging Trends in Defense and Space Tech

    36 min

About

Where startup meets government, academia, and global innovation Let’s talk opportunities. Across countries, industries, and sectors. We’re here to breakdown the network siloes to uncover emerging opportunities and ventures across the global startup ecosystem. This podcast is for founders, investors, academics, governments, and anyone who wants to nerd out with us on the creative ways startups can engage with various sectors and markets (and vice versa!).