In this episode of the FemHealth Nutrition Podcast, we explore why this well-known supplement is gaining traction across women’s health. We’ll cover: The basics of creatine metabolismWhat the research says across different life stagesCreatine’s potential benefits for strength, cognition, mood, and reproductive healthEvidence-based dosing strategies and safety considerations References Chilibeck, P. D., et al. (2023). A 2-year RCT on creatine and bone health. Medicine & Science in Sports & Exercise, 55(10), 1750–1760. de Guingand, D. L., et al. (2024). Creatine metabolism in human pregnancy. The American Journal of Clinical Nutrition, 119(4), 838–849.Gordon, A. N., et al. (2023). Creatine and recovery in active women. Nutrients, 15(3567).Gualano, B., et al. (2008). Effects of creatine supplementation on muscle function and functional capacity in older women. European Journal of Applied Physiology, 102(2), 223–231.Gutiérrez-Hellín, J., et al. (2025). Creatine beyond athletics. Nutrients, 17(95). Muccini, A. M., et al. (2021). Creatine in female reproduction. Nutrients, 13(490).Ostojic, S. M., et al. (2024). Creatine intake and reproductive outcomes. Food Science & Nutrition, 12, 4893–4898.Ireland, Z., et al. (2020). Creatine supplementation during pregnancy improves neonatal survival after birth asphyxia in rats. Pediatric Research, 88(2), 254–260.Smith-Ryan, A. E., et al. (2021). Creatine across the female lifespan. Nutrients, 13(877).Buford, T. W., et al. (2007). International Society of Sports Nutrition position stand: Creatine supplementation and exercise. Journal of the International Society of Sports Nutrition, 4(1), 6.Dos Santos, L., et al. (2023). Effects of creatine supplementation in postmenopausal women: A systematic review and meta-analysis. Frontiers in Physiology, 14, 1165912.Cooper, R., Naclerio, F., Allgrove, J., & Jimenez, A. (2012). Creatine supplementation with specific view to exercise/sports performance: an update. Journal of the International Society of Sports Nutrition, 9(1), 33.Lyoo, I. K., Yoon, S., Kim, J. E., Hwang, J., Kim, T. S., Won, W., Bae, S., & Renshaw, P. F. (2012). A randomized, double‑blind placebo‑controlled trial of oral creatine monohydrate augmentation for enhanced response to a selective serotonin reuptake inhibitor in women with major depressive disorder. The American Journal of Psychiatry, 169(9), 937–945. https://doi.org/10.1176/appi.ajp.2012.12010009 cureus.com+9pubmed.ncbi.nlm.nih.gov+9link.springer.com+9Chilibeck, P. D., Kaviani, M., Candow, D. G., & Zello, G. A. (2017). Effect of creatine supplementation during resistance training on lean tissue mass and muscular strength in older adults: A meta-analysis. Open Access Journal of Sports Medicine, 8, 213–226