PETRI DISH PERSPECTIVES

Manead Khin

Burma | ChicagoScientist 🥼🧪🔬Covering biotech, pharma, and healthcare companies shaping the world 🧬🏥🌎 Stream new episodes every THURSDAY! https://linktr.ee/maneadkhin #biotech #pharma #healthcare #podcast #petridishperspectives

  1. 36m ago

    October 2026: Biotech & Pharma NEWS Roundup

    Send us Fan Mail Welcome to your essential overview of the global biotech and pharmaceutical landscape for October 2026! This month was defined by a wave of oncology approvals, a head-to-head data drop that reshuffled the GLP-1 race, and M&A activity that shows Big Pharma is quietly pivoting away from oncology toward rare disease, pain, and RNA therapeutics. The FDA approved dostarlimab in locally advanced rectal cancer, tucatinib in HER2-positive breast cancer, and talazoparib plus enzalutamide in metastatic prostate cancer — three meaningful wins for patients in a single month. Lilly’s retatrutide beat Ozempic head-to-head with 20.9% weight loss in diabetic patients, cementing its status as the next major GLP-1 contender. On the deal front, Shionogi paid $2 billion for IntraBio in rare neurodegeneration, Viatris acquired Pacira BioSciences for $1.65 billion in non-opioid pain, and Merck KGaA bought Silence Therapeutics at a 130% premium — six deals totaling over $7 billion for the month. VC finished strong with Formation Bio raising $600 million to buy drug candidates and Dren Bio closing $350 million, part of over $1.4 billion in rounds in the final week alone. And HHS greenlighted six experimental peptides over the open objections of FDA career scientists — a regulatory move that signals growing tension between evidence standards and the current policy posture. The bigger story: capital is flowing, but it’s getting selective — and the therapeutic areas winning M&A attention this month tell you exactly where the smart money thinks the next decade of returns will come from. 🎧 Listen now, stay curious, and don’t forget to subscribe for new episodes! https://linktr.ee/maneadkhin #PetriDishPerspectives #BiotechNews #PharmaNews Support the show © 2026 The Perspective Bureau LLC. All rights reserved.

  2. 3d ago

    Episode 79: Endeavor Health

    Send us Fan Mail In this episode of Petri Dish Perspectives, we explore Endeavor Health, the Chicago-area hospital system most Illinoisans have driven past but couldn’t name. Born from Evanston Hospital in 1891, grown into NorthShore University HealthSystem, expanded through a 2022 merger with Edward-Elmhurst Health, and rebranded as Endeavor Health in December 2023, this is a system that has been quietly becoming one of the largest in the state. We break down Endeavor’s origins, its nine-hospital suburban footprint, the NorthShore Research Institute, and the financial reality of running a $6.4 billion system at near-zero operating margin and why that made what happened next almost inevitable. On October 14th, 2026, Endeavor and Rush University System for Health announced a proposed merger that would create a $10 billion combined system with 12 hospitals, 400+ care sites, 46,000 employees and clinicians, and over 2 million patients a year. We get into the deal mechanics, the leadership shake-up, the $1 billion endowment investment, and what nurses, patients, and healthcare economists are already pushing back on. This is a story about scale, survival, and what happens when a fragmented market finally stops pretending consolidation isn’t coming. 🎧 Listen now, stay curious, and don’t forget to subscribe for new episodes every Thursday! https://linktr.ee/maneadkhin #PetriDishPerspectives #EndeavorHealth #Rush #ChicagoHealthcare #HospitalMerger #HealthcareConsolidation #NorthShore #EdwardElmhurst #RushUniversity #HealthPolicy #HealthcareNews #LifeSciences #Healthcare #HealthcareLeadership #BiotechNews Support the show © 2026 The Perspective Bureau LLC. All rights reserved.

  3. Oct 15

    Episode 77: Revolution Medicines

    Send us Fan Mail In this episode of Petri Dish Perspectives, we explore Revolution Medicines, the precision oncology company that spent over a decade trying to drug one of cancer’s most notorious targets: RAS. With mutations present in roughly 30% of all new cancer diagnoses, including pancreatic, lung, and colorectal cancers, RAS has long been considered undruggable. Revolution bet their entire company on proving that wrong. We break down the science behind their tricomplex inhibitor platform, the three lead drugs in their pipeline, daraxonrasib, elironrasib, and zoldonrasib, and the landmark Phase 3 RASolute 302 results that showed unprecedented overall survival in metastatic pancreatic cancer, earned a Plenary presentation at ASCO 2026, and triggered an FDA NDA review. But this is also a story about the pressure of building an ambitious company with no revenue, nearly $1 billion in annual R&D spend, and a failed $30 billion acquisition attempt with Merck that sent the stock crashing 26% in a single day. Revolution walked away from the deal. The question now is whether that confidence was prescient or premature. 🎧 Listen now, stay curious, and don’t forget to subscribe for new episodes every Thursday! https://linktr.ee/maneadkhin #PetriDishPerspectives #RevolutionMedicines #RAS #KRAS #Oncology #PancreaticCancer #LungCancer #Daraxonrasib #Biotech #DrugDiscovery #PrecisionOncology #CancerResearch #FDA #LifeSciences #Healthcare #BiotechTok #BiotechNews Support the show © 2026 The Perspective Bureau LLC. All rights reserved.

  4. Oct 1

    September 2026: Biotech & Pharma NEWS Roundup

    Send us Fan Mail Welcome to your essential overview of the global biotech and pharmaceutical landscape for September 2026! This month was defined by blockbuster dealmaking, historic FDA approvals, and a growing recognition that pharmaceutical innovation is shifting east. AstraZeneca made a $2 billion strategic bet on Summit Therapeutics and its ivonescimab program, Novo Nordisk paid up to $2.6 billion for a once-weekly oral GLP-1 from China's Hengrui, and Eli Lilly continued its relentless dealmaking streak with a $3.25 billion InnoCare partnership. On the regulatory front, the FDA approved the first-ever treatment for Sanfilippo syndrome, a first-in-class Parkinson's drug, the world's first radioligand equivalent, and a new once-weekly insulin, a remarkable month for patients with rare and chronic diseases. ADARx raised $446 million in one of biotech's largest IPOs of the year, and Electra Therapeutics upsized its own raise to $350 million, signaling that the IPO window remains open for the right science. Meanwhile, Novo's total workforce cuts reached 13,000 and BMS continued trimming headcount, a reminder that even the industry's biggest players are restructuring for what comes next. The bigger story is unmistakable: China is no longer just manufacturing drugs for the West, it is discovering them, and the deals signed this month prove that Big Pharma has fully accepted that reality. 🎧 Listen now, stay curious, and don’t forget to subscribe for new episodes! https://linktr.ee/maneadkhin #PetriDishPerspectives #BiotechNews #PharmaNews Support the show © 2026 The Perspective Bureau LLC. All rights reserved.

About

Burma | ChicagoScientist 🥼🧪🔬Covering biotech, pharma, and healthcare companies shaping the world 🧬🏥🌎 Stream new episodes every THURSDAY! https://linktr.ee/maneadkhin #biotech #pharma #healthcare #podcast #petridishperspectives