Life With a Difference

Andy Collinson

A space to celebrate and empower individuals with visible differences.Through my work as a patient advocate I've had the privilege of meeting so many incredible people with stories that I believe we could all benefit from hearing.This podcast aims to share those stories, experiences, and journeys of those living with unique appearances. Through candid conversations and inspiring interviews, we aim to challenge stereotypes, foster understanding, increase empathy and kindness and build a community where everyone feels seen and heard.Join us as we explore topics ranging from self-acceptance and advocacy to the everyday triumphs and challenges faced by our guests. Whether you have a visible difference or simply want to learn more, you’re invited to be part of our conversation and discover the beauty in diversity.Subscribe now to help create a kinder and more inclusive world.

  1. Clinical trial participation basics with Professor Carsten Flohr

    2D AGO

    Clinical trial participation basics with Professor Carsten Flohr

    In this episode of Life With a Difference, I’m joined by Professor Carsten Flohr, Professor of Dermatology at St John’s Institute of Dermatology, King’s College London, and Consultant Dermatologist at Guy’s and St Thomas’ NHS Foundation Trust. Through my work as a patient advocate, I regularly encounter myths and misconceptions about clinical trials, from fears about being a “guinea pig” to concerns about safety, placebo, and being locked in once you start. This conversation is intended to help address those concerns and explain, in plain language, how clinical trials actually work. We also explore why trial participation is so vitally important. Without people choosing to take part, new medicines cannot be developed, tested, or approved. Clinical trials are the foundation of progress in medicine, and they are how safer, more effective treatments reach patients who desperately need them. What we cover 00:00 Intro 00:31 Who Professor Flohr is and why clinical trials matter 02:20 How medicines are developed, from discovery to post-marketing monitoring 03:50 Phase 1, 2, 3 and 4 explained 04:20 MHRA, NICE and NHS commissioning in the UK 06:05 QALYs and how NICE assesses value for money 08:10 What a clinical trial actually is 09:05 Common myths and misconceptions about trial participation 10:00 Trial design, washout periods and independent oversight 13:10 What a trial visit looks like in real life 16:30 Endpoints, placebo and open-label extensions 18:20 Your right to withdraw at any time 19:05 What happens when a trial ends 21:50 Why diversity in trials matters and who is under-represented 24:40 Reimbursement, remote trials and patient involvement 30:15 How to find clinical trials and trusted resources 38:05 Final advice for patients considering research Resources mentioned UK Clinical Trials Gateway ClinicalTrials.gov UK Dermatology Clinical Trials Network British Skin Foundation National Eczema Society Psoriasis Association NIHR Sponsorship and transparency This episode was sponsored by Novartis. Novartis had no editorial control over the content. This episode is non-promotional, for educational purposes only, and does not provide medical advice. No medicines are discussed or endorsed. Always speak to your clinician or research team for personal medical guidance.

    40 min
  2. FEB 11

    An Eczema emergency pathway | Holly Lloyd

    In this episode of Life With a Difference, I’m joined by Holly Lloyd, who has lived with eczema since infancy and, over the last year, experienced a level of severity that most people simply don’t understand. Holly’s story is hard, but it’s also incredibly practical, because she shares an emergency pathway that helped her access specialist dermatology care when things became unsafe. 00:00 Intro, why Holly’s story matters 00:09 Meet Holly, lifelong eczema and how 2025 escalated 01:03 Childhood eczema, bandages, then “growing out of it” 02:05 Eczema returns in her 20s, spread, and moving beyond topicals 03:22 The last 6 months, full body decline, rapid overnight flares 04:38 No sleep, severe inflammation, repeated infections 05:14 Why “eczema” gets minimised, the extreme end people don’t see 08:03 When Holly knew it wasn’t normal anymore 09:27 Complex case clinic, advocating hard, still no proper escalation 11:17 Moving back with her mum, surviving becomes “normal” 13:14 Private vs NHS routes, and how to push for specialist care 14:23 Holly researches Guy’s and St Thomas’, planning to self refer 15:56 The difference at Guy’s and St Thomas’, “human” and thorough 16:14 The emergency pathway, walking into A and E 16:33 Local hospital admissions, why it felt unsafe and insufficient 17:48 What went wrong in general hospital care 20:39 Discharged because blood markers looked “okay” 21:33 Why severe skin needs a real emergency pathway 23:19 Holly’s decision, taxi to St Thomas’ A and E 25:07 Rapid decline in the waiting room, admitted by 3am 27:04 The scary part, tick box medicine and missed urgency 29:31 Guy’s vs St Thomas’, how the hospitals work together 31:49 What happened after admission, being properly supported 32:17 Consultants travel over, “show us more”, thorough investigations 33:44 Patient lodge + dermatology day care clinic 35:24 The key takeaway, if you’re severe, this pathway exists 36:43 Being a mum, weighing risks, needing a break to survive 39:01 The mental health reality, severe eczema can be life threatening 40:32 Treatments tried and what’s next 46:10 Ongoing weekly follow ups, proper monitoring 47:24 Why care and practical support changes everything 49:42 If Holly ran the NHS, what needs to change 54:18 Sharing pathways, reach out, community support 55:08 Where to find Holly, and her offer to help others 56:47 Message to carers and supporters 57:17 Closing thoughts We talk about: • What severe, full body eczema can actually look and feel like • Repeated infections, loss of mobility, and the mental toll of living in constant fear of the next flare • Why “eczema” is often minimised, even when someone is genuinely in crisis • The difference between standard hospital care and specialist dermatology teams • The emergency route Holly used to access Guy’s and St Thomas’ care • The value of dermatology day care and what real support looks like when you are too unwell to care for yourself • Treatment decision making when you have tried everything and you are just trying to get your life back If you are living with severe eczema and feel stuck, please know you are not alone, and you deserve proper care. Holly on Instagram: @HollyLloydskin Social media: Instagram https://www.instagram.com/lifewithadifferencepodcast/ TikTok https://www.tiktok.com/@lifewithadifference Linkedin https://www.linkedin.com/in/andrew-collinson/ Please get in touch if I can help in any way Blog: https://www.lifewithadifference.info/ buymeacoffee.com/lifewithadifference

    58 min
  3. FEB 4

    "I felt like my life was over" | Life with Bell's Palsy: Gary Parsons

    Gary Parsons (as seen on Channel 4’s Love My Face) talks candidly about Bell’s palsy, facial paralysis, mental health, and what it really takes to live uninhibited.  We dig into the show’s mission, representation in the media, the gaps in NHS support (especially psychological care), practical roadmaps for patients and carers, and how advocacy and community can lighten the mental load of a long-term condition. Chapters 00:00 Intro 00:50 Gary’s story & Bell’s palsy 03:20 Inside Love My Face (Channel 4) 08:05 The show’s mission & impact 14:20 Causes, bilateral paralysis & anxiety of recurrence 19:15 Treatments, surgery, physio & Botox 24:10 Self-acceptance vs. the search for a “cure” 31:00 Advocacy, mental health & speaking from the “scar” 40:30 NHS experiences & the case for psychological support 48:20 A practical roadmap for patients & carers 52:05 Living uninhibited & owning your identity 1:05:00 Gary’s projects, Changing Faces, and where to find him Resources mentioned  • Changing Faces UK (support & representation)  • Facial Palsy UK (guidance, clinics, rehab tips) Connect with Gary Website: garyparsons.uk Social: @GaryParsonsUK If this helped you, please like 👍, subscribe, and share with anyone navigating visible difference, facial palsy, or long-term skin conditions. Your support helps more people find these conversations. #BellsPalsy #FacialParalysis #VisibleDifference #LoveMyFace #ChangingFaces #MentalHealth #SelfAcceptance #Dermatology #Advocacy #Channel4 #PatientVoice #ChronicIllness #UKNHS Social media: Instagram https://www.instagram.com/lifewithadifferencepodcast/ TikTok https://www.tiktok.com/@lifewithadifference Linkedin https://www.linkedin.com/in/andrew-collinson/ Please get in touch if I can help in any way Blog: https://www.lifewithadifference.info/ buymeacoffee.com/lifewithadifference

    1h 8m
  4. JAN 28

    'Empathy is undervalued" | Mark Doyle, Founder: A Life in a Day

    I am a huge believer in A Life in a Day's ability to create a world with more empathy, understanding and ultimately concession for patients. Our missions completely align and I very much look forward to supporting Mark and the team in any way I can. In this sponsored episode of Life With a Difference, I’m joined by Mark Doyle, founder of A Life in a Day, an immersive learning experience designed to help people working in healthcare walk in the shoes of someone living with a health condition for 24 hours. We talk about how the concept began, how the experience is built using a combination of an interactive app, live phone calls with actors, and a physical kit, and why it can create a level of empathy and understanding that is hard to achieve through conversation alone. Mark also shares how A Life in a Day developed its first therapy areas, from Crohn’s disease to heart failure and oncology, and what the team has learned about doing this work ethically by starting with patient stories first. We discuss the balance between realism and sensitivity, how they validate experiences with lived experience and medical professionals, and what meaningful outcomes can look like, from shifts in mindset to practical changes in trial design, communication, and patient support. If you work in healthcare, pharma, medical education, research delivery or simply want your team to have a higher level of empathy and you’re curious about building deeper patient understanding that leads to better outcomes, this conversation is for you. Sponsor disclosure This episode is sponsored by A Life in a Day. Sponsorship supports the production of Life With a Difference, but does not influence editorial content or guest perspectives. Learn more about A Life in a Day Website: https://alifeinaday.co.uk You can also find Mark and the team on LinkedIn. A Life in a Day run regular virtual taster sessions to give a short interactive introduction to how the experience works. 00:00 Intro 00:09 Mark Doyle introduces himself and A Life in a Day 00:48 How Andy and Mark connected at Patients as Partners 01:37 What A Life in a Day is, mission and purpose 02:25 Andy’s experience, why it isn’t gimmicky, emotional impact 03:33 Where the idea came from, how it started (2016) 04:56 First conditions, Crohn’s disease, then heart failure and oncology 06:30 Capturing the real grit, ethics, starting with patient stories 09:18 How the experience works, app, calls, kit, wearables, sensations 13:40 Why 24 hours matters, challenges across work, home, relationships 14:08 Challenges growing a unique product, access and funding for HCPs 16:21 Measuring success, learning, actions, and ROI for organisations 18:13 What changes after the experience, workshops and implementation 20:28 If funding was unlimited, reaching clinicians and students globally 32:53 Conditions that surprise people most, asthma, obesity, diabetes 35:09 Severity spectrum and why names can mislead public understanding 36:23 Empathy as a driver for action and change 37:32 Why patients often don’t have space to tell the full story 39:01 Why living it beats hearing it, the next step in advocacy 40:31 Five-year vision, making it part of healthcare education 42:14 How to get involved, taster sessions, website and LinkedIn 43:12 Closing thanks Social media: Instagram https://www.instagram.com/lifewithadifferencepodcast/ TikTok https://www.tiktok.com/@lifewithadifference Linkedin https://www.linkedin.com/in/andrew-collinson/ Please get in touch if I can help in any way Blog: https://www.lifewithadifference.info/ buymeacoffee.com/lifewithadifference

    44 min
  5. 10/01/2025

    "I felt like a burns victim" | Life with TSW: Amy Wilson

    In this episode of Life With a Difference, I speak with Amy (@Journey_of_Amy), who lives with severe eczema and is currently going through Topical Steroid Withdrawal (TSW). Amy shares openly about the physical pain, the mental health struggles, and the stigma of living with a visible difference. From being compared to a burns victim at her worst flare, to teaching children that “different is normal,” Amy’s honesty shines a light on what it’s really like to live with eczema on the extreme side of the spectrum. We discuss:  • What TSW (Topical Steroid Withdrawal) actually is  • The devastating physical symptoms: swelling, redness, bone-deep itch, flaking & peeling  • The mental toll of eczema and suicidal thoughts that many never talk about  • Her journey through treatments: methotrexate, dupilumab, Rinvoq, cyclosporine & more  • Why self-advocacy at dermatology appointments is essential  • How children and students respond to visible difference in the classroom  • The role of community and connection in coping with chronic illness  • Hope for the future with new treatments like lebrikizumab and nemolizumab Amy also talks about her work as a teacher, her growing advocacy on Instagram, and why she feels it’s her mission to raise awareness and help others feel less alone. 💬 Have you experienced eczema or TSW? Share your story in the comments — your voice matters. 👉 Subscribe to Life With a Difference for more honest conversations with patients, carers, and advocates. #Eczema #TopicalSteroidWithdrawal #VisibleDifference #TSW #LifeWithADifference #SkinConditions Social media: Instagram https://www.instagram.com/lifewithadifferencepodcast/ TikTok https://www.tiktok.com/@lifewithadifference Linkedin https://www.linkedin.com/in/andrew-collinson/ Please get in touch if I can help in any way Blog: https://www.lifewithadifference.info/ buymeacoffee.com/lifewithadifference

    1h 2m
  6. 09/24/2025

    Marriage, Caregiving & Chronic Illness | Donna Collinson

    In this very special episode of Life With a Difference, I sit down with my wife, Donna Collinson, to talk openly about what it means to love and care for someone living with a chronic skin condition and visible difference. Donna shares her perspective as both my partner and my carer, the moments of joy, the exhaustion, the unseen emotional weight, and the resilience it takes to navigate life together when atopic dermatitis (AD) dominates so much of our daily reality. We cover:  • How we first met and when Donna noticed my skin condition  • The hardest flare-ups and their impact on both of us  • The balance between “cracking on” vs giving in to bad days  • The hidden mental health toll of atopic dermatitis  • What carers and partners of people with chronic illness need too  • The lack of support for carers in the NHS  • Why open communication and empathy matter in relationships  • The importance of celebrating the good days 💬 Have you supported a loved one through chronic illness or visible difference? Share your story in the comments. 👉 Subscribe to Life With a Difference for more conversations with patients, carers, and advocates. #LifeWithADifference #VisibleDifference #AtopicDermatitis #ChronicIllness #Carers #SkinConditions Social media: Instagram https://www.instagram.com/lifewithadifferencepodcast/ TikTok https://www.tiktok.com/@lifewithadifference Linkedin https://www.linkedin.com/in/andrew-collinson/ Please get in touch if I can help in any way Blog: https://www.lifewithadifference.info/ buymeacoffee.com/lifewithadifference

    1h 6m
  7. 09/17/2025

    Sun Safety, Skin Research & Stigma | Lisa Bickerstaffe, British Skin Foundation

    n this episode of Life With a Difference, I sit down with Lisa Bickerstaffe, Head of Communications at the British Skin Foundation (BSF). Lisa has been with BSF for over a decade, leading campaigns that raise awareness of skin health, skin disease, and skin cancer while supporting vital dermatology research. We cover:  • The mission of the British Skin Foundation and why skin research matters  • How skin health campaigns have evolved with social media & TikTok trends  • The impact of sun safety and the award-winning “Burnable Billboard” campaign  • Psychological effects of living with a skin condition  • Stigma and discrimination faced by people with visible differences  • The importance of diverse skin images in healthcare and inclusive dermatology  • How the public can support BSF’s work and get involved ⸻ Show links: https://www.britishskinfoundation.org.uk/ https://www.britishskinfoundation.org.uk/which-sunscreen-is-right-for-me 🕒 Timestamps / Chapters 00:00 – Introduction 00:11 – Who is Lisa Bickerstaffe? 01:00 – How communications at BSF has evolved 02:20 – TikTok skin trends and social media challenges 03:43 – The British Skin Foundation’s mission 06:12 – Covering 2,000+ skin conditions with a small team 07:16 – Working as a team of eight at BSF 08:44 – Collaboration with other skin charities 10:17 – Psychological effects of skin conditions 12:01 – Sun safety & the importance of SPF from childhood 13:33 – Misconceptions about skin cancer 14:37 – Why skin conditions aren’t taken seriously enough 16:21 – Mineral vs chemical sunscreens explained 20:11 – The Burnable Billboard campaign 24:26 – Stigma and discrimination around skin conditions 27:16 – Teaching children about visible difference & kindness 30:52 – Reframe Project: inclusive medical images across skin tones 33:27 – The challenge of diagnosing conditions on darker skin 35:20 – Advocacy and the importance of pushing for referrals 36:28 – How patients can support BSF’s work 37:58 – Services BSF offers to patients & the A–Z of skin 40:26 – Educating children about equality and skin health in schools 43:40 – Upcoming BSF 30th anniversary projects (2026) 44:58 – Building community with patients & advocates 46:08 – Final thoughts: “We’re all united by skin” ⸻ 👉 Subscribe to Life With a Difference for more conversations with patients, clinicians, and advocates. #BritishSkinFoundation #Dermatology #SkinHealth #Eczema #SkinCancer #VisibleDifference Social media: Instagram https://www.instagram.com/lifewithadifferencepodcast/ TikTok https://www.tiktok.com/@lifewithadifference Linkedin https://www.linkedin.com/in/andrew-collinson/ Please get in touch if I can help in any way Blog: https://www.lifewithadifference.info/ buymeacoffee.com/lifewithadifference

    47 min

About

A space to celebrate and empower individuals with visible differences.Through my work as a patient advocate I've had the privilege of meeting so many incredible people with stories that I believe we could all benefit from hearing.This podcast aims to share those stories, experiences, and journeys of those living with unique appearances. Through candid conversations and inspiring interviews, we aim to challenge stereotypes, foster understanding, increase empathy and kindness and build a community where everyone feels seen and heard.Join us as we explore topics ranging from self-acceptance and advocacy to the everyday triumphs and challenges faced by our guests. Whether you have a visible difference or simply want to learn more, you’re invited to be part of our conversation and discover the beauty in diversity.Subscribe now to help create a kinder and more inclusive world.