Precision Pulse with Amit

Amit K Jain (AJ)

A thought-provoking series exploring the transformative impact of precision in health, lifestyle, and beyond. Through this podcast, our goal is to bring you conversations and insights that inspire a more intentional, precise approach to everyday life 

Episodes

  1. 3d ago

    Episode 10: Biofidelity - Making Genomics Simpler

    A lung cancer patient can have a targeted therapy available to them and never find out — because the biomarker test failed, took too long, or was never ordered. Dr. Barney Balmforth thinks that gap is an engineering problem, not a science problem.   In this episode of Precision Pulse,  Amit Jain  of  @Precision_Pulse_with_Amit sat down with  @BarneyBalmforth-Biofidelity , co-founder and CEO of  @Biofidelity   a molecular diagnostics company based in Cambridge, England    We talked about why comprehensive genomic profiling has become the default answer to questions that may not require it, what it takes to run guideline-recommended lung biomarker testing on PCR instruments labs already own, and why Biofidelity’s newer Enspyre technology goes after the inefficiency of sequencing itself rather than competing with it.   We also get into reimbursement and the regulatory path scenarios, the CellCarta partnership and what changed when it expanded to global exclusivity, and where Barney thinks the life sciences industry is structurally wrong right now.   — CHAPTERS — 00:00 The patients who never get tested 00:45 Welcome to Precision Pulse 02:15 From physics to cancer diagnostics 08:15 Why biomarker testing still does not reach patients 13:15 Aspyre: comprehensive lung testing on a standard PCR machine 20:15 Enspyre: the signal-to-noise problem inside sequencing 26:15 CellCarta, biopharma, and the commercial model 30:45 Near-term milestones and the five-year vision 35:15 Rapid fire 37:45 Closing thoughts #PrecisionMedicine #Diagnostics #LungCancer #Genomics #Oncology #MolecularDiagnostics #LiquidBiopsy #NGS #CancerResearch #HealthTech #LifeSciences #Biotech #precisiononcology  #podcastclips #podcast   #PrecisionPulse #biofidelity #precisionpulsewithamit #lungcancerawarenessmonth #lungcancerawareness #precisionmedicine  #diagnostics  #lungcancersymptoms

  2. Oct 13

    EP09 - Fighting Back: Boxing, Addiction, and the Search for What Works

    Precision medicine means the right treatment, for the right patient, at the right time. But what if precision goes beyond the clinic? In our latest Precision Beyond Medicine episode,  @jainamit74   of  @Precision_Pulse_with_Amit   sat down with Susanna, a boxing coach at  @titleboxingclub in Burlington, MA. Her path to recovery wasn’t a straight line. She struggled with anxiety and addiction, tried several approaches, and then walked into a boxing gym. What started as a workout turned into a source of discipline, confidence, community and, eventually, transformation. This isn’t really a boxing episode. It’s about finding what works for you. In this conversation we explore: 🥊 Life before the transformation, and struggling quietly while looking fine on the outside 🔍 Treatment vs. transformation: what helped, and what was still missing 💡 Why boxing worked, across physical, mental, emotional and social dimensions 🏃 Whether the lesson is boxing at all, or finding your thing (running, yoga, dance, hiking…) ❤️ What she would tell the version of herself who was struggling years ago Medication may help. Therapy may help. Community and movement may help. The real challenge is finding the right combination for each person. That’s precision beyond medicine. If this resonates, please subscribe and share it with someone who might need to hear it. This episode shares one person’s story and isn’t medical advice. If you’re dealing with anxiety, addiction or other mental health challenges, please work with a qualified professional. #PrecisionPulse #PrecisionBeyondMedicine #Recovery #MentalHealth #Boxing #LifestyleMedicine #Resilience #Wellbeing #Podcast #physicalactivity

  3. Jul 28

    Ep 08: Maternal Health Matters - Addressing Overlooked Pre- and Postnatal Health Challenges

    Episode 08: Every pregnancy should be a journey toward hope—not one overshadowed by preventable complications. In this powerful episode of @The Precision Pulse, Amit Kumar Jain (AJ)  sat down with Martina Mollers, founder of  Marti  Connecting Africa, to discuss one of the world's most important yet under-recognized healthcare challenges: pre- and postnatal complications, particularly in underserved and low-resource communities. Together, they explored: 🔹 Why maternal complications continue to impact millions of women worldwide 🔹 The warning signs that women and families should never ignore 🔹 How awareness, education, and timely intervention can save lives 🔹 Funding situation 🔹 The role of healthcare systems, policymakers, and communities in improving maternal outcomes 🔹 Why healthcare equity is essential for healthier mothers, babies, and families One message resonated throughout our conversation: Improving maternal health isn't only about better technology—it's about earlier awareness, better access, stronger communities, and ensuring every woman receives the care she deserves before, during, and after pregnancy. A heartfelt thank you to Martina for sharing her experience, passion, and commitment to advancing maternal health awareness across Africa and beyond. 🎧 listen now and join the conversation. #PrecisionPulse #MaternalHealth #WomensHealth #GlobalHealth #HealthcareEquity #PublicHealth #PatientAdvocacy #HealthcareInnovation #Pregnancy #PostpartumCare #Africa #Leadership #LifeSciences #Podcast

  4. Jul 9

    Episode 07: Detecting Cancer Before It Speaks: Public University, Patient Advocates & an Algorithm in Costa Rica

    What happens when a research university and a global patient-advocacy organization set out to catch cancer before symptoms appear? In this episode   ⁨ @jainamit74 of  ⁨ @Precision_Pulse_with_Amit sat with Rodrigo Mora of CICICA,  University of Costa Rica and Maria Lourdes of  ⁨ @Inspire2liveChannel and discussed real-world implementation of a clinical diagnostic test (OncoSeek) for early risk assessment across 9 types of cancer, built through a partnership between the University of Costa Rica (CICICA – Cirugía y Cáncer) and Inspire2Live in Costa Rica. Few moments that stayed with us forever: * If the algorithm flags a high risk of cancer, it can also determine the tissue of origin — not just whether someone is high-risk, but the possible location * In oncology, the problem is the huge waiting lists — patients wait a year for a colonoscopy, two years for a mammography. A tool that tells you whether you might have one of nine cancers offers real relief * Many physicians came to take the test themselves — even our health minister came to have it done. People really believe in this * Technology and patient education can't be separated — you have to be just as clear about a test's limitations as its promise Grateful to Rodrigo Mora and Maria Lourdes for a candid conversation #precisionmedicine  #diagnostics  #earlydetection  #cancerscreening  #cdx  #PatientAdvocacy #oncology  #NIAMBIO #lifestyle

About

A thought-provoking series exploring the transformative impact of precision in health, lifestyle, and beyond. Through this podcast, our goal is to bring you conversations and insights that inspire a more intentional, precise approach to everyday life