In this episode of the Canna Curious Podcast, Kyla slows things right down and returns to the foundations. Before conversations about strain names, dosing, or delivery methods before stigma, shame, or opinion this episode asks a simpler question: What is actually happening inside your body when you take cannabis? This episode is for patients. For women who turn to this plant not to escape their lives - but to cope with pain, stress, hormonal change, burnout, grief, or nervous system overload. At the centre of this conversation is the endocannabinoid system (ECS) a regulatory system that exists in all of us, whether we ever take cannabis or not. In this episode, Kyla explores: What the endocannabinoid system is - and why it’s not a “weed system,” but a core biological regulatorHow the ECS was identified in the 1990s through cannabinoid research by scientists including Ally Howlett and Raphael MechoulamThe three key components of the ECS: receptors, endocannabinoids, and enzymesThe roles of CB1 and CB2 receptors, and how THC and CBD interact with them differentlyWhy your body makes its own cannabinoids — and even passes them through breast milkWhy relief from cannabis looks different for everyone, and why variability is expected - not failureHow hormones, stress, nervous system state, and life stage (including perimenopause) influence responseThe difference between regulation and escape, and why many women use cannabis to stay present not numbWhy dosing can feel unpredictable, and why curiosity works better than rigid rulesHow one-size-fits-all advice often creates shame and what a body-literate approach offers insteadSupport the show Canna Curious is produced independently. If you’d like to support the podcast, you can Buy me a coffee Resources & Further Reading Understanding the Endocannabinoid System These sources support the explanation of the endocannabinoid system as a regulatory system involved in balance, pain, mood, sleep, inflammation, and stress: Di Marzo V, Piscitelli F. (2015). The endocannabinoid system and its modulation by phytocannabinoids.Neurotherapeutics, 12(4), 692–698. https://link.springer.com/article/10.1007/s13311-015-0376-6Lu HC, Mackie K. (2016). An introduction to the endogenous cannabinoid system. Biological Psychiatry, 79(7), 516–525. https://www.sciencedirect.com/science/article/pii/S0006322315002127Pertwee RG. (2015). Endocannabinoids and their pharmacological actions. Handbook of Experimental Pharmacology, 231, 1–37. "Send us a message" Support the show Connect with Kyla de Clifford Instagram: @cannacuriousaus TikTok: @cannacuriousau YouTube: @cannacurious If you enjoyed this episode, please follow, share, and leave a review - it helps the podcast reach more curious minds just like you. Disclaimer: We are not doctors, and this is not medical advice. Everything shared here is based on our personal lived experiences and the stories of others. Always speak with a qualified healthcare professional before making any changes to your health or wellness routine.