Clot, Clot, Who's There?

Vasculearn Network
  • 5.0 (2)
  • Medicine
  • Updated Monthly

Explore the world of thrombosis and hemostasis with "Clot Clot, Who's There?", a thought-provoking podcast brought to you by Vasculearn Network in collaboration with the Thrombosis and Haemostasis Editors (Thieme).

  1. Thoracic Outlet Syndrome: Evidence vs. Experience

    Jun 1

    Thoracic Outlet Syndrome: Evidence vs. Experience

    When a young, otherwise healthy patient presents with an upper extremity DVT, venous thoracic outlet syndrome should be high on the differential—but the diagnosis is often delayed or missed. Join experts JoMarie Monzon, MSN, FNP-BC and Drs. Donna Bahroloomi, Ali Azizzadeh, and Vincent Jongkind as they discuss: Why venous thoracic outlet syndrome is frequently mistaken for musculoskeletal injury Diagnostic challenges and the role of imaging Current approaches to thrombolysis, decompression, venous reconstruction, and anticoagulation Tune in now and subscribe to Clot, Clot, Who's There? for more expert conversations bridging science, practice, and global perspectives in thrombosis, hemostasis, and vascular medicine. 00:00: Introduction to Venous Thoracic Outlet Syndrome (VTOS) 05:37: Diagnosing VTOS & Understanding the Different Subtypes 10:26: Thrombolysis, Anticoagulation, and Timing of Decompression 14:45: Surgical Approaches, Vein Reconstruction, and Long-Term Outcomes 22:20: Postoperative Anticoagulation Strategies 24:28: Key Clinical Takeaways

    27 min
  2. Inside the Lab: Bypassing Factor Xa Inhibitors

    May 1

    Inside the Lab: Bypassing Factor Xa Inhibitors

    In urgent, high-stakes situations—like major bleeding or emergency surgery—how should clinicians assess coagulation in patients on factor Xa inhibitors? And more importantly, are we focusing on the right signal? Join global experts as they explore: Why traditional assays (PT/aPTT, anti-Xa) often fall short in critical decision-making The role of functional testing in assessing true hemostatic potential How VMX-C001, a novel bypassing agent, challenges conventional approaches to reversal and monitoring Be sure to read the VMX-C001 study discussed in the episode: https://www.rpthjournal.org/article/S2475-0379(26)00033-6/fulltext?dgcid=raven_jbs_etoc_email Tune in now and subscribe to Clot, Clot, Who's There? for more expert conversations bridging science, practice, and global perspectives in thrombosis, hemostasis, and vascular medicine. Chapters 00:00 Introduction & Clinical Challenge 02:54 Assessing Factor Xa Inhibitors in Urgent/Emergent Situations 05:29 Why Standard Assays Fall Short 09:38 Functional Testing: dPT & dRVVT 12:35 VMX-C001 & Future Directions This episode was made possible through generous support from VarmX.

    17 min
  3. Stopping the Second Stroke: Emerging Strategies in Secondary Prevention

    Apr 1

    Stopping the Second Stroke: Emerging Strategies in Secondary Prevention

    Surviving a stroke is only the beginning. Preventing the next one is where the real clinical challenge lies—and for patients with non-cardioembolic stroke, the existing toolkit has long fallen short. Join Drs. Geoff Barnes, Mike Sharma, and Valeria Caso as they explore: Stroke subtypes, recurrence risk, and the unique challenges of non-cardioembolic stroke and ESUS Why current treatment options have fallen short—and what may be next The advent of Factor XI inhibitors and what emerging data may mean for the future of secondary prevention Tune in now and subscribe to Clot, Clot, Who's There? for more expert conversations bridging science, practice, and global perspectives in thrombosis, hemostasis, and vascular medicine. 00:00: Introduction & Stroke Subtypes 03:59: Recurrence Risk & Key Risk Factors 07:24: Current Treatment Strategies 10:54: ESUS & Limits of Anticoagulation 14:19: Moving Beyond Aspirin 16:26: Factor XI Inhibitors: Data & Future Directions This episode was made possible through generous support from Bayer.

    26 min
  4. Precision Over Prescription: Antithrombotic Therapy and CAD

    Mar 2

    Precision Over Prescription: Antithrombotic Therapy and CAD

    When it comes to antithrombotic therapy in coronary artery disease, the central question is no longer "What should everyone get?" It's "What's right for this patient?" In this episode, Drs. Heather Johnson, Ty Gluckman, and Davide Cappodano explore the modern balance between managing clotting and bleeding risk in patients on antiplatelets and anticoagulants. From the evolving role of aspirin and P2Y12 monotherapy to dual pathway inhibition and the management of CAD with atrial fibrillation, the conversation highlights a clear shift: less one-size-fits-all medicine, more individualized—and shared—decision-making. Tune in now and subscribe to Clot, Clot, Who's There? for more expert conversations bridging science, practice, and global perspectives in thrombosis, hemostasis, and vascular medicine.   00:00 – Welcome & Introduction 03:57 – Is Aspirin Still King? 10:26 – Shorter DAPT, Earlier Monotherapy 14:09 – When More Is More: the COMPASS regimen 17:49 – When Less Is More: CAD + AF

    29 min
  5. AF Gone, Clot Still Knocking?

    Feb 9

    AF Gone, Clot Still Knocking?

    In this episode of Clot, Clot, Who's There? Drs. Christian Ruff (USA) and Giulio Francesco Romiti (Italy) chat about long-term anticoagulation management after successful atrial fibrillation ablation. They explore why stroke risk may persist despite rhythm control, examine emerging evidence from the ALONE-AF and OCEAN trials, and consider how patient selection and shared decision-making should inform post-ablation care. Tune in now and subscribe to Clot, Clot, Who's There? for more expert conversations bridging science, practice, and global perspectives in thrombosis, hemostasis, and vascular medicine. 00:00 Welcome & Introductions 01:12 Why Stroke Risk Persists After AF Ablation 04:19 The Anticoagulation Dilemma: Guidelines, Risk & Patient Priorities 09:45 New Evidence After Ablation: ALONE-AF & OCEAN 27:12 Key Takeaways, Shared Decision-Making & What's Next

    28 min
  6. What's Clotting in 2026?

    Jan 7

    What's Clotting in 2026?

    In this episode of Clot Clot Who's There, Aviva Schwartz, Director of Education at Vasculearn Network, speaks with Professor Gregory Lip about key anticoagulation and atrial fibrillation data from 2025 and what lies ahead in 2026. The discussion spans post–AF ablation management, holistic AF care, and emerging factor XI inhibitors shaping the future of thrombosis management. Tune in now and subscribe to Clot, Clot, Who's There? for more expert conversations bridging science, practice, and global perspectives in thrombosis, hemostasis, and vascular medicine.   Chapters: 00:00 Welcome and Introduction 01:59 2025 Trial Highlights: Anticoagulation in Stable CAD and AF Ablation 07:27 High-Risk AF and Holistic Care 10:10 What's Coming in 2026: Factor XI Inhibitors and Upcoming Trials 11:51 Guidelines vs. Real-World Practice

    15 min
  7. A Bridge Too Far? Navigating Perioperative Anticoagulation Challenges in Nonurgent Procedures

    12/01/2025

    A Bridge Too Far? Navigating Perioperative Anticoagulation Challenges in Nonurgent Procedures

    Host Dr. Alex Spyropoulos is joined by global experts Drs. James Douketis and Marc Samama for a focused, practical discussion on perioperative anticoagulation management in nonurgent procedures. Together, they clarify: When and how to safely interrupt warfarin and direct oral anticoagulants Why heparin bridging is now rarely needed How procedural bleeding risk and pharmacokinetics inform decision-making The episode reviews evidence from key clinical trials, outlines when anticoagulation can safely be continued for minimal-bleed-risk procedures, and explores future directions—including the potential role of Factor XI inhibitors in the perioperative setting. Don't miss this concise, guideline-driven conversation for clinicians managing anticoagulated patients or working within perioperative care teams. Tune in now and subscribe to Clot, Clot, Who's There? for more expert conversations bridging science, practice, and global perspectives in thrombosis, hemostasis, and vascular medicine.   00:00 – Welcome & Introductions 02:34 – Assessing Thrombotic vs. Bleeding Risk 08:56 – Warfarin Interruption & Bridging: What Changed? 16:39 – DOAC Management 23:34 – Procedure Playbook for Low Bleed Risk 29:29 – Future Directions: Factor XIs and Beyond

    32 min
  8. Antithrombotic Stewardship

    10/30/2025

    Antithrombotic Stewardship

    Host Tara Lech is joined by Drs. Scott Woller and Virginia Silvari for a thoughtful conversation on anticoagulation stewardship: what it is, why it matters, and how it can help patients who need antithrombotic therapy. They share examples from their own practice, talk through common challenges, and offer simple steps for improving care across settings. Topics: What makes anticoagulation stewardship different from traditional management How to choose the right anticoagulant for each patient Practical system-level steps to support safe prescribing Lessons from U.S. and European practices Tips for reassessing therapy and managing periprocedural care Tune in now and subscribe to Clot, Clot, Who's There? for more expert conversations bridging science, practice, and global perspectives in thrombosis, hemostasis, and vascular medicine.   00:00 Welcome & Setting the Stage 02:01 What "Antithrombotic Stewardship" Really Means 05:49 Choosing the Right Agent for the Right Patient 13:39 Reassessment, Follow-Up, & Real-World Impact 22:50 Perioperative Management & Building a Stewardship Culture

    30 min
See All (15)

Ratings & Reviews

5
out of 5
2 Ratings

About

Explore the world of thrombosis and hemostasis with "Clot Clot, Who's There?", a thought-provoking podcast brought to you by Vasculearn Network in collaboration with the Thrombosis and Haemostasis Editors (Thieme).

Information

  • Creator
    Vasculearn Network
  • Years Active
    2025 - 2026
  • Episodes
    15
  • Rating
    Clean
  • Copyright
    © 2025
  • Show Website
    Clot, Clot, Who's There?