Serenity and Fire with Krista

Krista Guagenti

Welcome to Serenity and Fire. The podcast where wellness meets grit. I'm your host, Krista Guagenti, founder of Panacea Luxury Spa Boutique. Join me as we dive into the intriguing world of bio-hacking, clean living, cutting-edge spa treatments and the hustle, grind and grit of entrepreneurship. From my personal battles with weight-loss and infertility, to a 30-year struggle to create and launch my dream business, to building a sanctuary for those touched by cancer — I'm here to share real talk, inspire big dreams and spark a passion for holistic living inside each and every one of you.

  1. 12/22/2025

    Sweeteners Made Simple: What Helps, What Hurts & What to Choose Instead

    Sweeteners are one of the most confusing, and misleading, parts of nutrition. In the third episode of this Sugar Series, I’m breaking down what actually happens in your body when you consume sugar, fruit, juice, honey, maple syrup, coconut sugar, artificial sweeteners, sugar alcohols, and the “natural” options everyone argues about online. For years, I thought I was making healthy choices, choosing honey over sugar, juice over soda, “clean” sweeteners over artificial ones. What I didn’t realize was how many of these options were still triggering hunger, cravings, insulin spikes, and fat storage beneath the surface. In this episode, I explain: Why whole fruit behaves completely differently than fruit juiceWhat really happens when fructose floods the liverWhy many “natural” sweeteners still spike insulinWhich sweeteners quietly worsen cravings and gut healthWhich options are actually the most metabolically gentleHow to think about sweeteners without fear, obsession, or restrictionBy the end of this conversation, you’ll understand sweeteners better than most health professionals were ever taught and you’ll feel confident making choices that support your energy, hunger, cravings, and long-term metabolic health. This episode isn’t about perfection. It’s about clarity. When you understand how sweeteners behave in the body, you stop blaming yourself — and start making decisions that actually work with your physiology instead of against it. ✨ Coming up next: In the next episode of the Sugar Series, I’m sharing my personal fasting experience, what my blood work revealed about metabolic flexibility, and how ketosis, fat burning, and GLUT4 activation actually work in real life. If this episode helped you see food differently, please share it with someone you love. And if you want to experience this work beyond the podcast, you can explore our metabolic-supportive treatments and biohacking therapies at Panacea Luxury Spa Boutique.

    24 min
  2. 12/15/2025

    Why Sugar Makes You Hungrier: Ghrelin, Leptin, Insulin & the Metabolic Trap

    If you’ve ever wondered why sugar seems to make you hungrier instead of full—why cravings hit hard even after you’ve eaten—this episode is going to change how you understand your body. In this episode, Krista breaks down the hormones and metabolic signals that quietly control hunger, fullness, cravings, and fat burning—often without us realizing it. We’re talking about ghrelin (your hunger hormone), leptin (your fullness hormone), insulin, and the metabolic trap so many people are stuck in today. You’ll learn why sugar spikes don’t just affect your waistline—they disrupt hormonal communication, shut down fat burning, intensify cravings, and keep you riding a glucose roller coaster all day long. And most importantly, you’ll understand why this isn’t a willpower issue or a personal failure—it’s physiology. In this episode, Krista explains: Why sugar increases hunger instead of satisfactionHow ghrelin surges during blood sugar crashesWhy leptin resistance leaves you feeling “full but not satisfied”How insulin blocks fat burning—even when you’re eating less or exercisingWhat a sugar crash actually is and why it triggers intense cravingsHow GLUT4 works and why movement is one of the most powerful metabolic tools you haveThis conversation is deep, eye-opening, and designed to give you clarity without shame. Once you understand what’s happening beneath the surface, you can stop fighting your body and start working with it. If sugar, cravings, stubborn weight gain, energy crashes, or feeling out of control around food has been a lifelong battle, this episode will help you connect the dots—and remind you that nothing is wrong with you. ✨ Stay tuned, because in the next episode of the Sugar Series, Krista breaks down fruit, sweeteners, and the myths around “healthy sugars”—including honey, stevia, monk fruit, sugar alcohols, and why whole fruit behaves very differently than fruit juice.

    16 min
  3. 12/01/2025

    Whiskey to Wellness, Part 2: Leadership Lessons, Motherhood Guilt & the Real Talk Women Need

    In Part Two of my conversation with Panacea’s Director of Operations, Jennifer York, we’re going even deeper into what it really looks like to lead with both grit and grace—while raising twin four-year-old girls and helping run a fast-paced luxury spa. We talk candidly about working for women vs. men, perfectionism, failure, friendship at work, and the emotional load that comes with being “the one” people look to when things go sideways. Jenn also opens up about the guilt of being a working mom, why she chose to go back to work after staying home, and how she’s learned to see problems as her greatest opportunities for growth. You’ll also hear some of the hilariously human stories that happen only in a spa (yes, including the amenities, tequila, and that stairwell incident), plus the quiet moments that make all of this worth it. In this episode, we explore: What changes when you go from peer to leader inside the same teamThe real differences Jen has felt working for male vs. female bossesHow perfectionism, fear, and procrastination show up in leadershipThe guilt and duality of being a working mom (especially with twins)Why “being a student” might be the most powerful leadership skillHow we navigate friendship, boundaries, and hard conversations togetherIf you’ve ever wondered whether you’re “doing enough” as a mom, leader, or entrepreneur—or if you’re just craving some honest behind-the-scenes of what it takes to build something meaningful—this conversation is for you.

    1h 10m
  4. 11/24/2025

    Distilling Passion: From Bourbon Barrels to Body Butter

    What do bourbon barrels, twin toddlers, and a luxury wellness spa have in common? Panacea's Director of Spa Operations, Jennifer York. In this episode, Krista sits down with Jenn— one of her closest confidants—to share the story behind the woman quietly keeping the entire operation running. From overseeing tourism at a major bourbon distillery in Kentucky to managing 50+ associates at a luxury spa in Ohio, Jenn’s path into wellness leadership is anything but ordinary. You’ll hear how she followed a wild intuitive nudge into massage school in the middle of COVID, navigated a surprise twin pregnancy, and ultimately made the leap from staying at home with her girls to taking on a demanding leadership role at Panacea. Along the way, Jenn opens up about the realities of: Going from bourbon barrels to body butters, and why hospitality is the bridge between both worldsThe mindset shift from “this is too hard” to “do it scared and do it anyway”What running high-volume bourbon tours taught her about timing, operations, and client expectationsThe personality differences between bourbon world and spa world—and why that matters for culture and hiringHow books, curiosity, and self-education shaped her leadership styleBalancing motherhood, marriage, and a very big job without losing herself in the chaosIf you’ve ever wondered what it really takes to keep a luxury spa running behind the scenes—or what it looks like to bet on yourself in the middle of a messy, imperfect season—this episode will speak to you. 🎧 Listen now and, if it resonates, follow the show, leave a review, or share this episode with someone who needs a reminder that it’s okay to do the big thing scared.

    54 min

About

Welcome to Serenity and Fire. The podcast where wellness meets grit. I'm your host, Krista Guagenti, founder of Panacea Luxury Spa Boutique. Join me as we dive into the intriguing world of bio-hacking, clean living, cutting-edge spa treatments and the hustle, grind and grit of entrepreneurship. From my personal battles with weight-loss and infertility, to a 30-year struggle to create and launch my dream business, to building a sanctuary for those touched by cancer — I'm here to share real talk, inspire big dreams and spark a passion for holistic living inside each and every one of you.