The Big Brain Podcast

The Block
  • 5.0 (2)
  • INVESTING

The Big Brain Podcast features conversations with crypto's most influential thinkers, builders, and traders. Co-hosted by The Block CEO Larry Cermak and MegaETH CSO Namik Muduroglu, these interviews challenge ideas, dig into mental models, and push guests beyond the headlines. This show isn't about predicting the future of crypto—it’s about spotlighting the big brains shaping it.

Episodes

  1. Gauntlet CEO Tarun Chitra on Why Exchange ADL Mechanisms Need an Update

    12/16/2025

    Gauntlet CEO Tarun Chitra on Why Exchange ADL Mechanisms Need an Update

    In episode 10 of The Big Brain Podcast, Larry and Namik are joined by Gauntlet founder and CEO Tarun Chitra. Tarun recounts how an unexpected ADL event on a tiny test position pushed him to research how exchanges handle insolvency when liquidations fail, especially after October 10th. He argues the common ranking approach concentrates losses unfairly and may overshoot during cascading events. The discussion also covers transparency, insurance funds, and why improving these systems matters if perp exchanges want to onboard new users. OUTLINE 00:00:00 - Introduction 00:00:54 - Tarun’s background 00:10:50 - Tarun's ADL paper 00:15:40 - ADL usage 00:26:25 - Transparency gap 00:31:44 - Critiques of Tarun's paper 00:36:32 - Impact of Tarun's paper 00:41:09 - Potential fixes 00:45:31 - Cult-like communities in crypto 00:52:42 - 10x verticals looking ahead 01:02:29 - Conclusion Guest links: Tarun Chitra - x.com/tarunchitra Gauntlet - x.com/gauntlet_xyz Show links: - Apple: apple.co/43F3vmq - Spotify: spoti.fi/44NT1lZ - Larry: x.com/lawmaster - Namik: x.com/NamikMuduroglu - The Block Podcasts: x.com/TheBlockPods --------------------------------------------------------------------------------- Subscribe to The Block's Newsletters! 🚨 Breaking News 👨‍🔬 Expert Analysis 📈 Market Insights Subscribe now 👉 https://www.theblock.co/newsletters --------------------------------------------------------------------------------- Hiring in crypto? 🧠 Find top talent fast with Campus, powered by The Block!✅ Challenge candidates with our Crypto Assessment Test⚡ Hire faster, build stronger teams Start your free trial today 👉 https://theblock.co/campus

    1h 3m
  2. Inside Infinex: Kain Warwick on building a 'superapp' to solve crypto's UX problem

    11/27/2025

    Inside Infinex: Kain Warwick on building a 'superapp' to solve crypto's UX problem

    In episode 9 of The Big Brain Podcast, Larry and Namik are joined by Infinex founder Kain Warwick. The trio discuss how crypto's complex user experience remains a roadblock for projects to gain broader adoption and find new users, and how Infinex aims to tackle this by being the first true "superapp." The conversation also digs into multi-chain routing, gas abstraction, fundraising, “CT mafia” dynamics, and how Infinex aims to compete with MetaMask, Phantom, and Coinbase Wallet. OUTLINE 0:00 – Introduction 2:51 – Evolution of Infinex Vision 5:30 – Decentralization vs User Experience 8:29 – Infinex in a Multi-Chain Future 12:30 – User Experience in Super Apps 15:10 – How Infinex Works Behind Scenes 19:25 – Funding Challenges for Super Apps 25:40 – YAP Run Drama Reflections 27:44 – Social Media’s Impact on Founders 29:56 – Navigating Crypto Regulations 31:25 – Token Distribution Strategies 34:09 – Token Launch & Listing Challenges 36:46 – On-Chain Liquidity & Multi-Chain 38:50 – Re-Engaging Users Online 41:28 – TGE Strategy Breakdown 44:40 – Token Utility & Revenue Models 51:53 – Competing in a Crowded Market Guest links: Kain Warwick - https://x.com/kaiynne Infinex on X - https://x.com/infinexInfinex - https://infinex.xyz/ Show links: Larry - https://x.com/lawmaster Namik - https://x.com/NamikMuduroglu

    55 min
  3. Lighter CEO on 'Democratizing Finance' with a zero-fee, ZK perp DEX

    11/25/2025

    Lighter CEO on 'Democratizing Finance' with a zero-fee, ZK perp DEX

    In episode 8 of The Big Brain Podcast, Lighter founder Vladimir Novakovski explains why he built a zero-fee, ZK-powered perp DEX as an Ethereum L2, how it stacks up against CEXs and rival perp chains, and what they learned from recent market stress ahead of their token launch. OUTLINE 00:00 – Introduction 04:50 – What Lighter is 06:15 – Why Ethereum L2 and ZK 11:03 – Zero-fee retail model 18:11 – Robinhood relationship & RH Chain 20:30 – L1 vs L2 value capture 27:08 – TGE timing and token value 30:29 – DYDX, Hyperliquid and CEX vs DeFi 35:52 – 10/10 crash and LLP risk 39:50 – Infra upgrades and closing Guest links: Vladimir Novakovski - https://x.com/vnovakovski Lighter - https://x.com/Lighter_xyz Show links: Larry - https://x.com/lawmaster Namik - https://x.com/NamikMuduroglu

    41 min
  4. ZCash Co-Founder: 'The World is Demanding More Privacy'

    11/25/2025

    ZCash Co-Founder: 'The World is Demanding More Privacy'

    In this episode of The Big Brain Podcast, Eli Ben-Sasson – co-founder of Zcash and Starknet – joins The Block President Larry Cermak and MegaETH CSO Namik Muduroglu. The conversation delves into the challenges of ensuring integrity in privacy payments on decentralized public blockchains, highlighting the role of ZK proofs in validating computations without compromising sensitive information. OUTLINE 00:00 Introduction 03:48 From Academia to Crypto 08:52 Zcash Privacy Overview 13:06 Monero vs. Zcash 15:05 The Future of Privacy 16:50 Quantum Threats 24:13 Zcash's Evolution 28:23 Starknet & BTCFi 33:13 Bitcoin's Future 41:08 Why Privacy Matters 43:14 The Future of Starknet Guest links: Eli Ben-Sasson - https://x.com/EliBenSasson Starknet BTCFi - https://www.starknet.io/blog/starknet-x-bitcoin-the-next-step-btcfi-on-starknet/ Show links: Larry - https://x.com/lawmaster Namik - https://x.com/NamikMuduroglu

    51 min

  5. 10/14/2025

    Breaking down crypto's biggest ever liquidation event with Wintermute founder Evgeny Gaevoy

    In this episode of the Big Brain Podcast, Larry and Namik are joined by Wintermute Founder and CEO Evgeny Gaevoy to discuss the recent historic crypto crash, explaining how extreme leverage, exchange failures, and forced ADL liquidations led to market chaos and liquidity breakdowns across the ecosystem. OUTLINE 00:00 Introduction 00:45 What Happened? 04:46 Understanding ADL 12:25 Transparency and Privacy on Hyperliquid  16:35 Circuit Breakers 19:16 Occam’s Razor 21:25 Assessing the Damage 25:24 Lessons learned 28:39 Looking Ahead 30:21 A Maturing Market 32:13 Dealing with Extreme Volatility  35:19 Impact on DeFi 37:28 Wintermute as the Crypto Villain 41:47 What else does Wintermute do? 44:11 Conclusion GUEST LINKS https://x.com/evgenygaevoy https://x.com/wintermute_t This episode of the Big Brain Podcast is brought to you by our sponsor, Canton Network. Are you hiring in crypto? Use Campus to quickly find your best candidates with our challenging Crypto Assessment Test.Faster hiring, stronger teams. Sign up for a trial today: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠theblock.co/campus⁠

    45 min
  6. Venture trends, regulatory wins, and consumer innovation: Tom Schmidt and Alok Vasudev on crypto's new era

    08/25/2025

    Venture trends, regulatory wins, and consumer innovation: Tom Schmidt and Alok Vasudev on crypto's new era

    In this episode of the Big Brain Podcast, Larry and Namik are joined by Dragonfly's Tom Schmidt Alok Vasudev of Standard Crypto. They dive into current trends in venture capital within the crypto space, touching on how market conditions have evolved since 2021, the role of treasury companies, and the evolving regulatory landscape. OUTLINE 00:00 Introduction 01:06 Alok's Background 04:45 Tom's Background 06:21 Cap Table Competition 07:53 Crypto 'Metas' 13:09 Copycat Crypto Projects 15:26 Brand Positioning 17:45 Web3 Moats 19:29 Crypto Treasury Companies 27:28 Regulatory Tailwinds 30:38 Consumer Adoption GUEST LINKS https://x.com/tomhschmidt https://x.com/AlokVasudev Are you hiring in crypto? Use Campus to quickly find your best candidates with our challenging Crypto Assessment Test.Faster hiring, stronger teams. Sign up for a trial today: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠theblock.co/campus⁠

    41 min
  7. How the US buying Bitcoin will rebuild American strength

    08/07/2025

    How the US buying Bitcoin will rebuild American strength

    Jack Mallers recounts his bitcoin journey, and explains how the US government could expunge its debt by dumping USD into gold and bitcoin. OUTLINE: 00:00 Introduction 06:55 Mallers Family Office 09:50 Founding Strike 14:53 Orange-Pilling El Salvador 22:23 Bitcoin & Tether 26:18 International Bitcoin Policies 32:39 US Bitcoin Policy 53:30 Twenty One

    1h 4m

  8. 06/23/2025

    Infinite Money Glitch: Paolo Ardoino shares Tether's vision for building a stable society

    In this episode, Paolo Ardoino delves into the factors that contributed to Tether’s USDT becoming the world’s largest stablecoin. Additionally, Ardoino discusses Tether’s strategic investment in AI, energy, biotech, and other industries, showcasing their long-term vision. OUTLINE: 00:00 Introduction 00:30 Paolo's Background 1:21 Tether's Path to Success 04:04 Stablecoin Policy 07:23 USDT Adoption in Emerging Markets 12:15 Tether Gold 16:30 Tether & US Hegemony 21:25 Responsible Crypto Education 22:54 Tether Wallet Development Kit 25:00 Chain Preferences 28:52 Tether's Investment Strategy 45:13 Infinite Money Glitch SHOW LINKS: Apple: https://apple.co/43F3vmq Spotify: https://spoti.fi/44NT1lZ Larry: https://x.com/lawmaster Namik: https://x.com/NamikMuduroglu The Block Podcasts: https://x.com/TheBlockPods GUEST LINKS: Paolo: https://x.com/paoloardoino Tether: https://tether.io/ Tether USDT: https://tether.to/ Tether Gold: https://gold.tether.to/ Holepunch: https://holepunch.to/ Keet: https://keet.io/ Wallet Development Kit: https://wallet.tether.io/

    49 min

  9. 06/11/2025

    DeFi Wizards: Rune Christensen and Guy Young on the past, present, and future of finance

    In this episode, Guy Young & Rune Christensen discuss the evolution of DeFi, noting how it has become more grounded in reality and sustainable business models, moving away from the early hype and ideological claims. OUTLINE: 00:00 Introduction 01:23 DeFi Ain't What it Used To Be 08:27 Ethena's Success 13:01 Get $HYPE(D) 15:08 HL L1 16:38 'Ecosystem Protocols' 19:32 DeFi User Capture 21:42 DeFi Endgame 22:05 Hyper-rational Users Onchain 24:53 Compressing DeFi Rates 27:16 Stealing  from the Rich 28:43Onchain KYC 30:57 Forking DeFi 33:57 The Future of Finance 37:50 'MicroStrategy Playbook" for Alts 42:19 Bitcoin DeFi? 43:57 F.A.F.O. Onchain SHOW LINKS: - Apple: https://apple.co/43F3vmq - Spotify: https://spoti.fi/44NT1lZ - Larry: https://x.com/lawmaster - Namik: https://x.com/NamikMuduroglu - The Block Podcasts: https://x.com/TheBlockPods GUEST LINKS: - Rune: @RuneKek - Guy: @gdog97_ - Sky: https://sky.money/ - Ethena: https://ethena.fi/

    50 min

  10. 05/23/2025

    Winning the Crypto Long Game

    The Big Brain Podcast is co-hosted by The Block CEO Larry Cermak and MegaETH CSO Namik Muduroglu. In this episode, Haseeb Qureshi & Jordi Alexander discuss the similarities between poker and crypto, the economics of bitcoin's endgame, the intersection of AI and crypto, and more. OUTLINE: 00:00 Introduction 02:25 Similarities between Poker & Crypto 06:33 Maintaining Crypto Conviction 12:40 Surviving the FTX Fallout 17:55 FTX Marketing Spend 24:05 The Trump Era of Crypto 26:34 Bitcoin Endgame Economics 34:32 Crypto & AGI 43:07 Analysts vs. LLMs 47:47 Market Making & AI 51:52 F.A.F.O. Onchain SHOW LINKS: - Apple: https://apple.co/43F3vmq - Spotify: https://spoti.fi/44NT1lZ - Larry: https://x.com/lawmaster - Namik: https://x.com/NamikMuduroglu - The Block Podcasts: https://x.com/TheBlockPods GUEST LINKS: - Haseeb: https://x.com/hosseeb - Jordi: https://x.com/gametheorizing EPISODE LINKS: - AI 2027: https://ai-2027.com/ - Noise: https://www.noise.xyz/ - Dave White Thread: https://x.com/_Dave__White_/status/1866497496773804434

    1 hr
  11. The Big Brain Podcast: Teaser

    EPISODE 1

    The Big Brain Podcast: Teaser

    It's gonna be a big show.

    14 sec

Trailer

Ratings & Reviews

5
out of 5
2 Ratings

About

The Big Brain Podcast features conversations with crypto's most influential thinkers, builders, and traders. Co-hosted by The Block CEO Larry Cermak and MegaETH CSO Namik Muduroglu, these interviews challenge ideas, dig into mental models, and push guests beyond the headlines. This show isn't about predicting the future of crypto—it’s about spotlighting the big brains shaping it.

Information

  • Creator
    The Block
  • Years Active
    2K
  • Episodes
    11
  • Rating
    Explicit
  • Copyright
    © 2026 The Block
  • Show Website
    The Big Brain Podcast

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