LipidCurious

Vishnu Priya Pulipati, MD, FACE, DipABCL

Podcast dedicated to demystifying lipids for medical boards and real-world clinical practice.

  1. JAN 16

    ASCVD Risk Stratification Series (Part 1 of 3): Before the Risk Calculator

    ASCVD risk stratification should be straightforward, but in real clinic time, it often isn’t. Multiple guidelines, limited time, overlapping categories, and nonstop competing priorities make lipid decisions feel harder than they need to be. In Part 1 of this LipidCurious mini-series, I walk you through how I approach ASCVD risk BEFORE I ever open an ASCVD Risk calculator using a practical, repeatable framework grounded in the 2018 AHA/ACC guideline, with AACE, NLA, and ADA guidance layered in where it adds clarity. In this episode, we cover: Why ASCVD risk stratification mattersWhere I start every single time (screening & what to check)The THREE questions that guide most lipid decisions!Clinical ASCVD?LDL-C ≥190 mg/dL?Diabetes Mellitus age 40–75?Bonus: You’ll also hear two quick cases that show how much you can decide without a calculator. Want a companion resource? Download the free LipidCurious Starter Kit here Questions or feedback? hello@lipidcurious.com   Join the Learn at Pinnacle app ⁠to earn FREE CE Credit for listening to this episode!  Disclaimer: This podcast is intended for educational purposes for clinicians and healthcare professionals. It does not provide medical advice, establish a physician–patient relationship, or replace individualized clinical judgment. The opinions expressed are those of the creator and do not represent the views of any affiliated institutions or organizations.

    16 min
  2. 11/14/2025

    Season 1 Episode 9: Atherosclerosis

    Most heart attacks don’t start with a clogged artery! They start with a microscopic storm — a small, invisible wound inside the artery wall. That storm begins decades before symptoms, sometimes before high school. By the time someone hits their forties or fifties, the real question isn’t whether atherosclerosis has begun…It’s how far it’s already gone. Let’s zoom in — literally inside the artery wall — and trace this disease from its very first spark. From the moment an ApoB-containing particle sneaks beneath the endothelium… To the slow, simmering inflammation that follows… To the day a plaque finally stops being silent. In this episode of LipidCurious, we’ll uncover  Anatomy & The Birth of an Atherosclerotic PlaqueWhy Some Arteries Are More Prone to AtherosclerosisSeeing, Treating, and Reversing AtherosclerosisYou’ll walk away seeing cholesterol numbers in a completely different light — not as abstract labs, but as a daily pressure on the artery wall. By the end, you’ll understand why atherosclerosis is the slow burn beneath the surface — invisible for years, yet capable of erupting into the events we fear most.  Bonus: The Visual Guide for this episode is waiting for you — click here. For the full collection of visuals across episodes, visit the Podcast page. Download the Free LipidCurious Starter Kit here Questions or feedback? Reach out at hello@lipidcurious.com  Join the Learn at Pinnacle app ⁠to earn FREE CE Credit for listening to this episode!  Disclaimer: This podcast is intended for educational purposes for clinicians and healthcare professionals. It does not provide medical advice, establish a physician–patient relationship, or replace individualized clinical judgment. The opinions expressed are those of the creator and do not represent the views of any affiliated institutions or organizations.

    16 min
  3. 10/31/2025

    Season 1 Episode 8: Lipoprotein (a)

    LDL may get all the blame — but there’s a darker twin hiding in the shadows. Same cholesterol core. Same ApoB backbone. But with one sinister twist: a sticky tail called apolipoprotein(a). That extra piece transforms an ordinary LDL particle into something far more dangerous.  Meet Lipoprotein(a) — or Lp(a) — one of the strongest, most under-recognized genetic drivers of premature cardiovascular disease. It’s pro-atherogenic, pro-thrombotic, and pro-inflammatory — a triple threat that can quietly turn even the healthiest-looking lipid panel into a ticking time bomb.  In this episode of LipidCurious, we’ll uncover  1.    What is Lp(a)?  2.    How and when to test for it?  3.    What to do when Lp(a) is high? We’ll walk through genetics, testing strategy, and real-world management — plus a glimpse into the promising therapies now in late-phase trials. By the end, you’ll understand why Lp(a) is the ghost in the lipid story — invisible on a standard panel, but capable of haunting even the fittest hearts.  Bonus: The Visual Guide for this episode is waiting for you — click here. For the full collection of visuals across episodes, visit the Podcast page. Download the Free LipidCurious Starter Kit here Questions or feedback? Reach out at hello@lipidcurious.com  Join the Learn at Pinnacle app ⁠to earn FREE CE Credit for listening to this episode!  Disclaimer: This podcast is intended for educational purposes for clinicians and healthcare professionals. It does not provide medical advice, establish a physician–patient relationship, or replace individualized clinical judgment. The opinions expressed are those of the creator and do not represent the views of any affiliated institutions or organizations.

    14 min

Ratings & Reviews

5
out of 5
7 Ratings

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Podcast dedicated to demystifying lipids for medical boards and real-world clinical practice.

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