LipidCurious

Vishnu Priya Pulipati, MD, FACE, DipABCL

Podcast dedicated to demystifying lipids for medical boards and real-world clinical practice.

Episodes

  1. NOV 14

    Season 1 Episode 9: Atherosclerosis

    Most heart attacks don’t start with a clogged artery! They start with a microscopic storm — a small, invisible wound inside the artery wall. That storm begins decades before symptoms, sometimes before high school. By the time someone hits their forties or fifties, the real question isn’t whether atherosclerosis has begun…It’s how far it’s already gone. Let’s zoom in — literally inside the artery wall — and trace this disease from its very first spark. From the moment an ApoB-containing particle sneaks beneath the endothelium… To the slow, simmering inflammation that follows… To the day a plaque finally stops being silent. In this episode of LipidCurious, we’ll uncover  Anatomy & The Birth of an Atherosclerotic PlaqueWhy Some Arteries Are More Prone to AtherosclerosisSeeing, Treating, and Reversing AtherosclerosisYou’ll walk away seeing cholesterol numbers in a completely different light — not as abstract labs, but as a daily pressure on the artery wall. By the end, you’ll understand why atherosclerosis is the slow burn beneath the surface — invisible for years, yet capable of erupting into the events we fear most.  Bonus: The Visual Guide for this episode is waiting for you — click here. For the full collection of visuals across episodes, visit the Podcast page. Download the Free LipidCurious Starter Kit here Questions or feedback? Reach out at hello@lipidcurious.com  Disclaimer: This podcast is intended for educational purposes for clinicians and healthcare professionals. It does not provide medical advice, establish a physician–patient relationship, or replace individualized clinical judgment. The opinions expressed are those of the creator and do not represent the views of any affiliated institutions or organizations.

    16 min
  2. OCT 31

    Season 1 Episode 8: Lipoprotein (a)

    LDL may get all the blame — but there’s a darker twin hiding in the shadows. Same cholesterol core. Same ApoB backbone. But with one sinister twist: a sticky tail called apolipoprotein(a). That extra piece transforms an ordinary LDL particle into something far more dangerous.  Meet Lipoprotein(a) — or Lp(a) — one of the strongest, most under-recognized genetic drivers of premature cardiovascular disease. It’s pro-atherogenic, pro-thrombotic, and pro-inflammatory — a triple threat that can quietly turn even the healthiest-looking lipid panel into a ticking time bomb.  In this episode of LipidCurious, we’ll uncover  1.    What is Lp(a)?  2.    How and when to test for it?  3.    What to do when Lp(a) is high? We’ll walk through genetics, testing strategy, and real-world management — plus a glimpse into the promising therapies now in late-phase trials. By the end, you’ll understand why Lp(a) is the ghost in the lipid story — invisible on a standard panel, but capable of haunting even the fittest hearts.  Bonus: The Visual Guide for this episode is waiting for you — click here. For the full collection of visuals across episodes, visit the Podcast page. Download the Free LipidCurious Starter Kit here Questions or feedback? Reach out at hello@lipidcurious.com  Disclaimer: This podcast is intended for educational purposes for clinicians and healthcare professionals. It does not provide medical advice, establish a physician–patient relationship, or replace individualized clinical judgment. The opinions expressed are those of the creator and do not represent the views of any affiliated institutions or organizations.

    14 min
  3. OCT 17

    Season 1 Episode 7: Apolipoprotein B

    LDL-C is the number we’ve all been trained to chase. But what if the real culprit isn’t the cholesterol itself… but the number of particles carrying it?  Meet ApoB — the quiet truth-teller of lipidology. It doesn’t care how perfect your LDL number looks. It counts every atherogenic particle capable of injuring the arterial wall — the true measure of risk hiding beneath the surface.  In this episode of LipidCurious, we’ll dig into what makes ApoB the stronger, sharper, and more honest marker of atherogenic burden:  1.    Why ApoB is a better measure of atherogenic burden  2.    How ApoB drives atherosclerosis  3.    How ApoB fits into clinical practice  We’ll also explore practical takeaways — when to order ApoB, what cutoffs to use, and how to apply it when your LDL and ApoB numbers don’t agree. By the end, you’ll see why every atherogenic particle counts — and why ApoB just might be the number that finally tells the truth about cardiovascular risk. Bonus: The Visual Guide for this episode is waiting for you — click here. For the full collection of visuals across episodes, visit the Podcast page. Download the Free LipidCurious Starter Kit here Questions or feedback? Reach out at hello@lipidcurious.com  Disclaimer: This podcast is intended for educational purposes for clinicians and healthcare professionals. It does not provide medical advice, establish a physician–patient relationship, or replace individualized clinical judgment. The opinions expressed are those of the creator and do not represent the views of any affiliated institutions or organizations.

    15 min

Ratings & Reviews

5
out of 5
5 Ratings

About

Podcast dedicated to demystifying lipids for medical boards and real-world clinical practice.

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