Hope & Histamine: The Paediatric Allergy Podcast

Goodlife Creations

“Helping you understand allergies—one episode at a time” Welcome to Hope & Histamine, the trusted podcast for families navigating the complex world of paediatric allergies. Hosted by a dedicated healthcare professional, this show offers clear, compassionate, and evidence-based guidance on the diagnosis, treatment, and day-to-day management of allergies and atopic conditions in children. From eczema to food allergies, asthma to anaphylaxis, each episode breaks down medical facts into practical advice—empowering parents, caregivers, and patients with reliable information and hope. Tune in for expert insights, real stories, and up-to-date recommendations designed to help you breathe a little easier.

  1. 5d ago

    Newborn Bathing & Baby Skincare: Can They Prevent Eczema? Insights from the EAACI Global Survey

    Could a newborn’s first bath and early skincare routine influence their risk of developing eczema? In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore an EAACI task force global survey of 319 international specialists, examining clinicians’ recommendations on neonatal bathing, baby skincare and the prevention of atopic dermatitis. We discuss when to give the first bath, how to cleanse delicate newborn skin, and recommendations on moisturisers. We also explore why most respondents advised preserving vernix caseosa, the protective coating present on a newborn’s skin, and its role in supporting the developing skin barrier. With advice varying considerably between countries and regions, what can clinicians and parents take away from these findings? We distinguish professional recommendations from proven prevention strategies and consider why further research is needed to develop consistent, evidence-based guidance. Join us to explore newborn skin care, bathing practices, skin barrier protection and eczema prevention, alongside the questions that remain unanswered. Source:  Beken, B., Carvalho, D., Brough, H.A., Arasi, S., Feleszko, W., Garcia-Abujeta, J., Khaleva, E., Moniri, A., Riggioni, C. and Tsabouri, S. (2026) 'Clinicians' recommendations on neonatal bathing and skin care in the context of atopic dermatitis prevention: An EAACI task force report', Pediatric Allergy and Immunology, 37, e70527. doi:10.1111/pai.70527. 🎧 Listen now on Apple Podcasts, Spotify, Amazon Music, and YouTube Disclaimer: The information shared in this podcast and on this website is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your doctor or a qualified healthcare provider with any questions you may have about a medical condition. Please don't ignore or delay seeking medical advice based on content from this podcast or website. Buy me a coffee: https://coff.ee/goodlifecreations Hope & Histamine: The Paediatric Allergy Podcast brings you expert interviews, evidence-based discussions and practical clinical updates on paediatric allergy, immunology and related conditions to support healthcare professionals in everyday practice. 🎧 Listen and subscribe: https://hopeandhistaminepodcasts.buzzsprout.com If you enjoyed this episode, please subscribe, leave a review, and share it with colleagues to help advance the care of children with rare allergic and immunological conditions. Send us Fan Mail Support the show Brought to you by - Goodlife Creations (2026).  Music by - Denys Kyshchuk from Pixabay.

  2. Oct 22

    Nasal Steroids in Children: Allergic Rhinitis, Adenoids & Safety—What Does the Evidence Say?

    Are nasal steroid sprays safe for children—and when do they really help? In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore intranasal corticosteroids in children, from treating allergic rhinitis and hay fever to their potential role in enlarged adenoids and nasal obstruction. Drawing on a 2026 review in Pediatric Allergy and Immunology, we unpack the evidence behind these widely used treatments and address questions that matter to clinicians and families: • How effective are nasal steroids for childhood allergic rhinitis? • Can they help children with enlarged adenoids, snoring or sleep-disordered breathing? • What does the evidence show for sinusitis and glue ear? • How do fluticasone, mometasone and other intranasal corticosteroids differ? • What should we know about nosebleeds, systemic absorption and potential effects on growth? Discover where the evidence is strongest, where uncertainty remains, and why appropriate treatment selection and correct nasal spray technique matter. Whether you’re a paediatrician, GP, pharmacist or parent, join us for an accessible, evidence-informed discussion of nasal steroids, childhood nasal allergies and paediatric upper airway inflammation. Source: Papadopoulou, A., Papadopoulos, M. and Tsabouri, S. (2026) 'Intranasal corticosteroids in pediatric airway inflammation: From pharmacokinetics and evidence to optimized clinical practice', Pediatric Allergy and Immunology, 37, e70514.  🎧 Listen now on Apple Podcasts, Spotify, Amazon Music, and YouTube Disclaimer: The information shared in this podcast and on this website is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your doctor or a qualified healthcare provider with any questions you may have about a medical condition. Please don't ignore or delay seeking medical advice based on content from this podcast or website. Buy me a coffee: https://coff.ee/goodlifecreations Hope & Histamine: The Paediatric Allergy Podcast brings you expert interviews, evidence-based discussions and practical clinical updates on paediatric allergy, immunology and related conditions to support healthcare professionals in everyday practice. 🎧 Listen and subscribe: https://hopeandhistaminepodcasts.buzzsprout.com If you enjoyed this episode, please subscribe, leave a review, and share it with colleagues to help advance the care of children with rare allergic and immunological conditions. Send us Fan Mail Support the show Brought to you by - Goodlife Creations (2026).  Music by - Denys Kyshchuk from Pixabay.

  3. Oct 12

    Paediatric Asthma Update: What’s New in Childhood Asthma Management?

    What’s new in childhood asthma care—and what does it mean for everyday practice? In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore recent advances in paediatric asthma management, from inhaled treatments and personalised care to the evolving role of biologics in severe asthma. We discuss key questions around asthma diagnosis, inhaler technique, treatment adherence and preventing exacerbations, alongside emerging approaches to help children achieve better asthma control. Designed for paediatricians, GPs, nurses and other healthcare professionals caring for children with asthma, this episode brings an accessible clinical perspective to a rapidly changing field. Source:  Dhochak, N., Robinson, P.F.M. and Saglani, S. (2026) 'Update on Pediatric asthma management: Recent advances', Pediatric Allergy and Immunology, 37, e70480. doi: 10.1111/pai.70480. 🎧 Listen now on Apple Podcasts, Spotify, Amazon Music, and YouTube Disclaimer: The information shared in this podcast and on this website is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your doctor or a qualified healthcare provider with any questions you may have about a medical condition. Please don't ignore or delay seeking medical advice based on content from this podcast or website. Buy me a coffee: https://coff.ee/goodlifecreations Hope & Histamine: The Paediatric Allergy Podcast brings you expert interviews, evidence-based discussions and practical clinical updates on paediatric allergy, immunology and related conditions to support healthcare professionals in everyday practice. 🎧 Listen and subscribe: https://hopeandhistaminepodcasts.buzzsprout.com If you enjoyed this episode, please subscribe, leave a review, and share it with colleagues to help advance the care of children with rare allergic and immunological conditions. Send us Fan Mail Support the show Brought to you by - Goodlife Creations (2026).  Music by - Denys Kyshchuk from Pixabay.

  4. Oct 3

    Omalizumab vs Oral Immunotherapy for Multiple Food Allergies: OUtMATCH Trial Explained

    How does omalizumab compare with oral immunotherapy for treating multiple food allergies? In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore OUtMATCH Stage 2, comparing omalizumab (Xolair) with omalizumab-facilitated multi-allergen oral immunotherapy (OIT). We unpack the findings on treatment success, allergic reactions, side effects and treatment discontinuation—and explain why tolerability matters when interpreting the results. What do these findings mean for children with peanut allergy and other food allergies, their families, and the clinicians supporting them? Join us for an accessible, evidence-based discussion of anti-IgE therapy, food allergy desensitisation and personalised treatment decisions. Whether you’re a paediatrician, allergist, trainee or parent, discover what the OUtMATCH trial adds to the evolving conversation about multifood allergy treatment. Sources: Wood, R.A. et al. (2024) 'Omalizumab for the Treatment of Multiple Food Allergies', New England Journal of Medicine, 390(10), pp. 889–899. doi: 10.1056/NEJMoa2312382.Wood, R.A. et al. (2026) 'Treatment of Multifood Allergy With Omalizumab or Multiallergen Oral Immunotherapy: A Randomized Clinical Trial', JAMA Pediatrics, Advance online publication. doi: 10.1001/jamapediatrics.2026.2910. 🎧 Listen now on Apple Podcasts, Spotify, Amazon Music, and YouTube Disclaimer: The information shared in this podcast and on this website is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your doctor or a qualified healthcare provider with any questions you may have about a medical condition. Please don't ignore or delay seeking medical advice based on content from this podcast or website. Buy me a coffee: https://coff.ee/goodlifecreations Hope & Histamine: The Paediatric Allergy Podcast brings you expert interviews, evidence-based discussions and practical clinical updates on paediatric allergy, immunology and related conditions to support healthcare professionals in everyday practice. 🎧 Listen and subscribe: https://hopeandhistaminepodcasts.buzzsprout.com If you enjoyed this episode, please subscribe, leave a review, and share it with colleagues to help advance the care of children with rare allergic and immunological conditions. Send us Fan Mail Support the show Brought to you by - Goodlife Creations (2026).  Music by - Denys Kyshchuk from Pixabay.

  5. Sep 22

    Eggs and Peanuts in Pregnancy: Why More Didn’t Reduce Infant Allergy Risk

    Can eating more eggs and peanuts during pregnancy and breastfeeding reduce a baby’s risk of developing food allergy? In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we examine the PrEggNut trial, a large randomised study involving more than 2,100 pregnant women whose babies had a strong family history of allergic disease. Researchers compared a maternal diet rich in eggs and peanuts with a standard-intake diet from pregnancy until four months after birth. Despite greater maternal exposure, the high-intake diet did not significantly reduce egg or peanut allergy in infants at one year of age. We explore the study’s findings, its strengths and limitations, and what the results mean for maternal diet, breastfeeding and current approaches to preventing food allergy in children. A concise, evidence-based discussion for parents, paediatricians, allergy professionals and anyone interested in pregnancy nutrition and infant allergy prevention. Source: Palmer, D.J., Sullivan, T.R., Campbell, D.E., Netting, M.J., McWilliam, V., Perrett, K.P., Makrides, M., et al. (2026)'Trial of a Maternal Diet Rich in Eggs and Peanuts to Reduce Infant Allergy', New England Journal of Medicine, 395(11), pp. 1090–1099. doi: 10.1056/NEJMoa2605659. 🎧 Listen now on Apple Podcasts, Spotify, Amazon Music, and YouTube Disclaimer: The information shared in this podcast and on this website is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your doctor or a qualified healthcare provider with any questions you may have about a medical condition. Please don't ignore or delay seeking medical advice based on content from this podcast or website. Buy me a coffee: https://coff.ee/goodlifecreations Hope & Histamine: The Paediatric Allergy Podcast brings you expert interviews, evidence-based discussions and practical clinical updates on paediatric allergy, immunology and related conditions to support healthcare professionals in everyday practice. 🎧 Listen and subscribe: https://hopeandhistaminepodcasts.buzzsprout.com If you enjoyed this episode, please subscribe, leave a review, and share it with colleagues to help advance the care of children with rare allergic and immunological conditions. Send us Fan Mail Support the show Brought to you by - Goodlife Creations (2026).  Music by - Denys Kyshchuk from Pixabay.

  6. Sep 13

    Kounis Syndrome Explained: When a Severe Allergic Reaction Triggers Acute Coronary Syndrome

    What happens when a severe allergic reaction affects not only the skin and airways but also the coronary arteries? In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore Kounis syndrome—an acute coronary syndrome triggered by an allergic or hypersensitivity reaction. We discuss how mast-cell activation and inflammatory mediators can cause coronary artery spasm, plaque disruption or stent thrombosis, resulting in symptoms that may resemble a heart attack alongside features of anaphylaxis. Discover the common triggers, different clinical types, warning signs, diagnostic challenges and key management considerations. This episode also examines the delicate balance involved in treating anaphylaxis and cardiac ischaemia simultaneously. An essential listen for paediatricians, allergists, emergency clinicians, cardiologists, trainees and anyone interested in the important connection between allergy and the heart. Sources: Anastasopoulou, M., Karanasos, A., Grafanaki, K., Almpanis, G., Koutsogiannis, N., Mplani, V., Papadionysiou, C., Kounis, N.G., Georgiou, S. and Davlouros, P. (2026) 'Incidence of Elevated Cardiac Biomarkers in Patients Presenting to the Emergency Department With Allergic Symptoms: Implications for the Diagnosis of Kounis Syndrome', The American Journal of Cardiology, 258, pp. 1–8. doi: 10.1016/j.amjcard.2025.08.036.Ceasovschih, A., Kounis, N.G., Markos, S., Ejubovic, M., Cherska, M., Barkas, F., Ristovski, V., Corlateanu, A., Sivapalan, P., Kotlyarov, S., Sorodoc, V. and Sorodoc, L. (2026) 'Kounis Syndrome Features in Special Populations', Medical Sciences, MDPI, pp. 1–20.Foti Randazzese, S., Caminiti, L., Crisafulli, G., Giovannini, M., Kounis, N.G. and Manti, S. (2024) 'Kounis syndrome in an adolescent with lipid transfer protein allergy', Pediatric Allergy and Immunology, 35, p. e14239. doi: 10.1111/pai.14239.Kalambay, J.D., Tashli, M., Zaman, M., Elwidaa, A., Shet, V. and Phillip, M. (2026) 'Kounis Syndrome: A Systematic Review and Meta-analysis', The American Journal of Cardiology, 268, pp. 25–31. doi: 10.1016/j.amjcard.2026.03.019. 🎧 Listen now on Apple Podcasts, Spotify, Amazon Music, and YouTube Disclaimer: The information shared in this podcast and on this website is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your doctor or a qualified healthcare provider with any questions you may have about a medical condition. Please don't ignore or delay seeking medical advice based on content from this podcast or website. Buy me a coffee: https://coff.ee/goodlifecreations Hope & Histamine: The Paediatric Allergy Podcast brings you expert interviews, evidence-based discussions and practical clinical updates on paediatric allergy, immunology and related conditions to support healthcare professionals in everyday practice. 🎧 Listen and subscribe: https://hopeandhistaminepodcasts.buzzsprout.com If you enjoyed this episode, please subscribe, leave a review, and share it with colleagues to help improve awareness of hereditary angioedema and advance the care of children with rare allergic and immunological conditions. Send us Fan Mail Support the show Brought to you by - Goodlife Creations (2026).  Music by - Denys Kyshchuk from Pixabay.

  7. Sep 7

    Rethinking the Blue Inhaler: Budesonide–Formoterol vs Salbutamol in Children with Mild Asthma | The CARE Trial

    Is it time to rethink the traditional blue reliever inhaler for children with mild asthma? In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we examine the landmark 2025 CARE trial published in The Lancet. This 52-week randomised controlled trial compared budesonide–formoterol with salbutamol as reliever therapy in children with mild asthma. We explore whether an anti-inflammatory reliever inhaler can provide better protection than salbutamol alone, examining the trial’s findings on asthma attacks, symptom control, safety and treatment burden. We also consider what the results could mean for paediatric asthma guidelines, clinical practice and conversations with children and their families. Whether you are a paediatrician, GP, nurse, pharmacist, trainee or parent, this episode offers a clear and clinically relevant discussion of a study that could reshape how mild childhood asthma is managed. Listen now to discover whether budesonide–formoterol could represent the future of reliever therapy for children with mild asthma. Source: Hatter, L., Holliday, M., Oldfield, K., Kearns, C., Barry, T., Black, M., Bruce, P., Colman, A., Dickinson, E., Eathorne, A., Harwood, M., Hills, T., Lamb, R., Kerse, K., Krishnamoorthy, S., Martindale, J., Semprini, A., Shortt, N., McNamara, D., Byrnes, C.A., Dalziel, S.R., Bush, A., Weatherall, M. and Beasley, R., 2025.Budesonide–formoterol versus salbutamol as reliever therapy in children with mild asthma (CARE): a 52-week, open-label, multicentre, superiority, randomised controlled trial. The Lancet, 406, pp. 1473–1483. Available at: https://doi.org/10.1016/S0140-6736(25)00861-X. 🎧 Listen now on Apple Podcasts, Spotify, Amazon Music, and YouTube Disclaimer: The information shared in this podcast and on this website is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your doctor or a qualified healthcare provider with any questions you may have about a medical condition. Please don't ignore or delay seeking medical advice based on content from this podcast or website. Buy me a coffee: https://coff.ee/goodlifecreations Hope & Histamine: The Paediatric Allergy Podcast brings you expert interviews, evidence-based discussions and practical clinical updates on paediatric allergy, immunology and related conditions to support healthcare professionals in everyday practice. 🎧 Listen and subscribe: https://hopeandhistaminepodcasts.buzzsprout.com If you enjoyed this episode, please subscribe, leave a review, and share it with colleagues to help improve awareness of hereditary angioedema and advance the care of children with rare allergic and immunological conditions. Send us Fan Mail Support the show Brought to you by - Goodlife Creations (2026).  Music by - Denys Kyshchuk from Pixabay.

  8. Aug 28

    The Peanut Patch Revolution: Is Epicutaneous Immunotherapy the Future of Peanut Allergy Treatment in Children?

    Could a simple skin patch transform the treatment of peanut allergy in young children? In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore the latest evidence on epicutaneous immunotherapy (EPIT)—also known as the peanut patch—for toddlers and children with peanut allergy. Drawing on findings from the EPITOPE and EPOPEX studies, we examine how peanut patch therapy works, its long-term effectiveness and safety, and whether it can increase the amount of peanut a child can tolerate. We also discuss its potential to reduce the risk of allergic reactions from accidental exposure to packaged foods and consider how well EPIT works in children who also have atopic conditions such as eczema, asthma and allergic rhinitis. Can epicutaneous immunotherapy offer families meaningful protection while avoiding some of the challenges associated with oral immunotherapy? Could the peanut patch become part of routine childhood peanut allergy treatment? Join us as we translate the emerging research into clear, practical information for parents, clinicians and everyone interested in the future of paediatric food allergy care. Sources: Burks, A., Sindher, S., Wang, J., O'Sullivan, M., Du Toit, G., Kim, E., Bois, T. and Greenhawt, M., 2022. EPITOPE study results: Phase 3, randomized, double-blind, placebo-controlled study of epicutaneous immunotherapy in peanut-allergic toddlers [Abstract]. Annals of Allergy, Asthma & Immunology, 129(5 Supplement), p. S12.Greenhawt, M., Wang, J., DuToit, G., O’Sullivan, M., Brown-Whitehorn, T., Bois, T., Bee, K., Green, T., Sampson, H. and Burks, A., 2025. Long-term efficacy and safety of epicutaneous immunotherapy in peanut-allergic toddlers: EPOPEX end of study results [Abstract]. Annals of Allergy, Asthma & Immunology, 135(5 Supplement), p. S10. Remington, B.C., Krone, T., Kim, E.H., Bird, J.A., Green, T.D., Lack, G., Fleischer, D.M. and Koppelman, S.J., 2019. Estimated risk reduction to packaged food reactions by epicutaneous immunotherapy (EPIT) for peanut allergy. Annals of Allergy, Asthma & Immunology, 123(5), pp. 488-493. Scurlock, A.M., Fleischer, D.M., Du Toit, G., Arends, N.J.T., Pongracic, J.A., Trujillo, J., Turner, P., Vogelberg, C., Bee, K.J., Green, T.D., Meney, J., Bois, T., Campbell, D.E., Sampson, H.A. and Burks, A.W., 2025. Efficacy and safety of epicutaneous immunotherapy in children with peanut allergy with atopic comorbidities. Annals of Allergy, Asthma & Immunology, 135(2), pp. 203-210. 🎧 Listen now on Apple Podcasts, Spotify, Amazon Music, and YouTube Disclaimer: The information shared in this podcast and on this website is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your doctor or a qualified healthcare provider with any questions you may have about a medical condition. Please don't ignore or delay seeking medical advice based on content from this podcast or website. Buy me a coffee: https://coff.ee/goodlifecreations Send us Fan Mail Support the show Brought to you by - Goodlife Creations (2026).  Music by - Denys Kyshchuk from Pixabay.

About

“Helping you understand allergies—one episode at a time” Welcome to Hope & Histamine, the trusted podcast for families navigating the complex world of paediatric allergies. Hosted by a dedicated healthcare professional, this show offers clear, compassionate, and evidence-based guidance on the diagnosis, treatment, and day-to-day management of allergies and atopic conditions in children. From eczema to food allergies, asthma to anaphylaxis, each episode breaks down medical facts into practical advice—empowering parents, caregivers, and patients with reliable information and hope. Tune in for expert insights, real stories, and up-to-date recommendations designed to help you breathe a little easier.