The Director's Desk

National Institutes of Health

The Director’s Desk is the official podcast of the National Institutes of Health, hosted by NIH Director Dr. Jay Bhattacharya. Join Dr. Bhattacharya as he speaks with NIH researchers, leaders, and community members about their work, experiences, and the science driving medical progress. Get an inside look at the people and stories shaping the future of biomedical research.

Episodes

  1. 2D AGO

    Is Fluoride Safe? The Science Behind Dental Health

    Fluoride, oral health, dental infections, and the science behind cavity prevention take center stage in this episode of The Director’s Desk. NIH Director Dr. Jay Bhattacharya sits down with Dr. Jennifer Webster-Cyriaque, Acting Director of the National Institute of Dental and Craniofacial Research (NIDCR), to discuss why dental health is essential to overall health — and what the latest NIH-supported research reveals about preventing tooth decay and serious oral infections. Tooth decay remains one of the most common chronic diseases worldwide. When untreated, cavities and gum disease can progress beyond the mouth, leading to bloodstream infections and severe systemic complications. Dr. Webster-Cyriaque explains the science behind oral bacteria, infection risk, and why prevention, early treatment, and community water fluoridation continue to play a critical role in public health. In this conversation, they explore: • The health consequences of untreated cavities and oral infections• The connection between oral health and systemic disease• The evidence behind fluoride and cavity prevention• NIH-supported dental and craniofacial research• Health equity and reducing disparities in oral health care• Dr. Webster-Cyriaque’s scientific career and leadership at NIDCR This episode highlights a central message of biomedical research and public health: oral health is integral to overall health. Subscribe to The Director’s Desk for more conversations with NIH leaders advancing evidence-based medicine, dental research, and public health innovation.

    35 min
  2. 12/16/2025

    HHS & NIH Evidence Review on Pediatric Gender Dysphoria — Expert Panel Discussion

    In this episode of The Director’s Desk, NIH Director Dr. Jay Bhattacharya hosts a roundtable with the primary authors of the new HHS peer-reviewed report, “Treatment for Pediatric Gender Dysphoria: Review of Evidence and Best Practices.” This comprehensive federal review evaluates the scientific evidence behind current pediatric gender dysphoria treatments—including puberty blockers, cross-sex hormones, and surgical interventions—and concludes that these approaches carry significant and long-term risks for children and adolescents. Featured Authors & Contributors:• Evgenia Abbruzzese – Society for Evidence-Based Gender Medicine• Alex Byre, PhD – Massachusetts Institute of Technology• Farr Curlin, MD – Duke University• Moti Gorin, PhD, MBE – Colorado State University• Kristopher Kaliebe, MD, DFAACAP – University of South Florida• Michael K. Laidlaw, MD – Michael K. Laidlaw MD, Inc.• Kathleen McDeavitt, MD – Baylor College of Medicine• Leor Sapir, PhD – Manhattan Institute for Policy Research• Yuan Zhang, PhD – Evidence Bridge• Additional contributors to the HHS evidence review and peer-review process Together, they discuss the report’s major findings, the strength and limitations of the existing evidence base, long-term clinical outcomes, and the implications for research, clinical practice, and public health policy. To learn more or read the full HHS report, visit HHS.gov.

    1h 48m
4
out of 5
15 Ratings

About

The Director’s Desk is the official podcast of the National Institutes of Health, hosted by NIH Director Dr. Jay Bhattacharya. Join Dr. Bhattacharya as he speaks with NIH researchers, leaders, and community members about their work, experiences, and the science driving medical progress. Get an inside look at the people and stories shaping the future of biomedical research.