Incumbents and Insurgents in Healthcare

with Eric Larsen

Incumbents and Insurgents, sponsored by TowerBrook Capital Partners, is a candid series about the collision - and collaboration - between healthcare and technology. Hosted by Eric Larsen, President of the TowerBrook Healthcare Institute, the show explores how incumbent healthcare organizations are adopting AI, how tech insurgents are challenging entrenched models, and what it will take to improve outcomes while bending the cost curve.

Episodes

  1. JAN 6

    Dario Amodei

    In this episode of Incumbents and Insurgents, Eric Larsen speaks with Dario Amodei, Co-Founder and CEO of Anthropic, about what happens when rapidly improving AI systems meet a healthcare sector built for stability and caution. They discuss the pace of model progress, why healthcare’s labor intensity and administrative burden make it especially exposed, and where AI is already acting as a clinical second opinion. The conversation spans physician workflows, biomedical discovery, and the gap between invention and diffusion, before turning to what increasingly capable machines mean for human judgment, creativity, and the role of the humanities in an age of abundant intelligence.

    54 min

  2. 12/18/2025

    Vinod Khosla

    In this episode of Incumbents and Insurgents, Eric Larsen sits down with Vinod Khosla - Founder of Khosla Ventures and one of the most prescient technologists of the past 50 years - for a wide-ranging conversation on how artificial intelligence will fundamentally rewire healthcare. They explore why healthcare has resisted disruption while other industries have not; how AI can reduce overhead while expanding clinical capacity; and how “free expertise” will upend primary care, specialty access, and mental health delivery. In addition, they cover labor economics, capitation, medical superintelligence, and regulation - before confronting the risks of the U.S. falling behind China and the Gulf states in healthcare AI.

    1h 13m

  3. 08/07/2025

    Eugene Woods and Bret Taylor

    In this episode of Incumbents and Insurgents, Eric Larsen hosts Bret Taylor (Co-Founder of Sierra, Chairman of OpenAI) and Eugene A. Woods (CEO of Advocate Health) for a conversation on how AI is driving transformation in healthcare. Topics include how health systems are deploying GenAI to reduce administrative overhead and prevent patient harm; how incumbents and insurgents can partner without talking past each other; and why real change depends as much on cultural alignment as technological capability.

    1 hr

  4. 08/07/2025

    Introducing Incumbents and Insurgents

    Ian Sacks, Managing Partner of TowerBrook Capital Partners, and Eric Larsen, President of TowerBrook Advisors, introduce Incumbents and Insurgents.

    15 min
  • 4 Episodes

Ratings & Reviews

5
out of 5
7 Ratings

About

Incumbents and Insurgents, sponsored by TowerBrook Capital Partners, is a candid series about the collision - and collaboration - between healthcare and technology. Hosted by Eric Larsen, President of the TowerBrook Healthcare Institute, the show explores how incumbent healthcare organizations are adopting AI, how tech insurgents are challenging entrenched models, and what it will take to improve outcomes while bending the cost curve.

Information

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