VetEmCrit: The Veterinary Emergency & Critical Care Podcast

Dr. Igor Yankin, DACVECC and Dr. Lance Wheeler, DACVECC

Practical, evidence-based insights into veterinary emergency and critical care.

  1. 5d ago

    Episode 33: Extracorporeal Purification Therapy - Is It Indicated?

    Free tool: https://academy.vetemcrit.com/ecpt The VetEmCrit Academy built for ER and ICU vets who want to grow, level up, and learn together: https://academy.vetemcrit.com/join In this episode we walk you through a new decision support tool we built for the Academy - Extracorporeal Therapy: Is It Indicated? It covers renal replacement therapy, hemoperfusion and therapeutic plasma exchange in dogs and cats, and it is written for those who do not run these circuits ourselves, because the hard part is knowing whether a particular patient might benefit, how urgent the call is, and whom to call. The tool asks three questions behind one front door: does this AKI or acute-on-chronic patient meet a published trigger for a renal replacement therapy consultation, is this an immune-mediated disease where plasma exchange might help, and can this toxin be removed with a circuit. We start with the kidney arm and the pre-check it forces you through first - a hypotensive dog and an obstructed cat can both carry a high creatinine, and neither belongs on a dialysis referral on that number alone - then the creatinine trend and hydration status that make the IRIS trigger what it is, the urine output step with its maintenance-rate warning, and a worked case in a 20-kilo dog that lands on "call a dialysis center now". From there we move to the immune-mediated arm, and we finish with the poisoning arm: the five numbers that decide whether extracorporeal removal can work, the four published questions in sequence, the carprofen half-life arithmetic, and the modality algorithm and pharmacokinetic table you can work through for your own case. It is built on three recent best practice consensus guidelines. The tool for members: https://academy.vetemcrit.com/ecpt. Video tutorials: https://academy.vetemcrit.com/tools-demo Academy members can also watch the video version in the Renal module of VetEmCrit Academy Rounds, followed by a short quiz with three new cases to test how well you navigate the tool. If you enjoy this episode and want the full experience, weekly deep-dives, interactive simulators, and clinical algorithms you can use on shift, come join us inside the VetEmCrit Academy.

    Episode 33: Extracorporeal Purification Therapy - Is It Indicated?
  2. Oct 12

    Episode 31: Patient Suffering in the ICU

    The VetEmCrit Academy built for ER and ICU vets who want to grow, level up, and learn together: https://academy.vetemcrit.com/join In this episode of Wheeler the Healer: Small Animal Emergency and Critical Care, Lance Wheeler, DVM, DACVECC explores patient suffering in the veterinary ICU and reframes it as both an ethical and physiologic problem rather than simply an emotional one. Inspired primarily by Chapter 12 of Small Animal Critical Care Medicine, 3rd edition, the episode examines primal alert signals like dyspnea, pain, nausea, thirst, hunger, anxiety, and sleep deprivation, emphasizing that critically ill animals often experience many of these simultaneously. The discussion reviews why air hunger may be more distressing than pain, how untreated nausea and sleep disruption can worsen recovery, and how ICU noise, repeated handling, and hospitalization stress may contribute to physiologic instability. Integrating recent literature on dyspnea-targeted therapy, anxiolytics, feline environmental modification, wireless monitoring, and individualized nursing care, the episode focuses on practical strategies to reduce suffering in real time. Ultimately, the episode argues that comfort-focused interventions are not separate from critical care—they are a fundamental part of stabilizing the critically ill patient. If you enjoy this episode and want the full experience, weekly deep-dives, interactive simulators, and clinical algorithms you can use on shift, come join us inside the VetEmCrit Academy.

    Episode 31: Patient Suffering in the ICU
  3. Sep 11

    Episode 28: Hyperthermia and Fever

    The VetEmCrit Academy built for ER and ICU vets who want to grow, level up, and learn together: https://academy.vetemcrit.com/join In this episode, Dr. Lance Wheeler, DVM, DACVECC tackles the number we take on every single patient and misread more often than any other - body temperature, and the fork in the road between true fever and nonfebrile hyperthermia. Drawing from Chapter 10 of Small Animal Critical Care Medicine (3rd edition) by James Miller, Lance separates a regulated, cytokine- and prostaglandin-mediated change in the hypothalamic set point from a straightforward failure of heat balance, and walks through a practical, structured framework for reading temperature in real time: thermoregulation in the preoptic anterior hypothalamus and the heat gain, conservation, and loss mechanisms behind it, exogenous versus endogenous pyrogens and the interleukin-1, interleukin-6, and tumor necrosis factor alpha pathway to prostaglandin E2, why fever can be protective in infection and harmful in brain injury, the roughly 7 percent rise in water and caloric requirement for every 1°F above normal, and the thresholds worth memorizing - above 102.5°F is elevated, above 106°F demands immediate total body cooling, and 107°F is the organ injury danger zone. He then moves into the causes and the bedside management, including heat stroke and the closed car that exceeds 120°F in under 20 minutes on a 75°F day, nucleated red blood cells as a prognostic marker, exertional hyperthermia and hyperpyrexic syndrome, eclampsia and seizures as heat sources you have to switch off rather than cool around, malignant hyperthermia and dantrolene, opioid-associated hyperthermia in cats, why lukewarm beats ice water and why you stop active cooling at 103°F, and why antibiotics are not antipyretics. Along the way, he integrates the latest veterinary evidence, including 2020-2026 studies on juvenile canine pyrexia, triage temperature as a predictor of outcome in cats, buprenorphine and postoperative hyperthermia, cooling strategies in working dogs, nose and axillary temperature accuracy, feline vector-borne disease, and heat-related mortality, and closes with a high-yield rapid-fire board review covering every key number worth memorizing. If you enjoy this episode and want the full experience, weekly deep-dives, interactive simulators, and clinical algorithms you can use on shift, come join us inside the VetEmCrit Academy.

    Episode 28: Hyperthermia and Fever
  4. Aug 28

    Episode 27: The Endothelial Glycocalyx — The Vascular Barrier We Keep Accidentally Punching

    The VetEmCrit Academy built for ER and ICU vets who want to grow, level up, and learn together: https://academy.vetemcrit.com/join In this episode, Dr. Lance Wheeler, DVM, DACVECC tackles the vascular structure we damage constantly and almost never measure - the endothelial surface layer, and why a patient's blood pressure can look better while the microcirculation is still a disaster. Drawing from Chapter 9 of Small Animal Critical Care Medicine (3rd edition) by Lisa Smart and Deborah Silverstein, Lance builds the anatomy from the ground up using a forest analogy, with syndecans and glypican-1 as the trunks, heparan sulfate and chondroitin and dermatan sulfate as the branches, hyaluronan as the undergrowth, and the immobile plasma layer as fog trapped inside the canopy, then connects that structure to the revised Starling principle, the protein-poor subglycocalyx space, and why sustained capillary reabsorption does not happen the way most of us were taught. He then moves into how the layer gets shed and what that costs at the bedside, including trauma, inflammation, hyperglycemia, hemodilution and hypervolemia as the major hits, thrombin and plasmin cleaving syndecan ectodomains, lipopolysaccharide accelerating shedding, glycocalyx fragments acting as DAMPs that amplify the very inflammation that caused them, perfused boundary region as an inverse measure of glycocalyx thickness, and loss of hemodynamic coherence when the monitor improves but the tissue does not. Along the way, he integrates the latest veterinary evidence, including 2021-2026 studies on perioperative crystalloid rate and circulating hyaluronan, fluid challenges in healthy anesthetized cats, shelf-stable blood products in a canine hemorrhagic shock model, fresh-frozen plasma in critically ill dogs, trauma biomarker dynamics over 24 hours, feline hemotropic mycoplasmosis, and cardiopulmonary bypass, and closes with a high-yield rapid-fire board review covering every key number worth memorizing. If you enjoy this episode and want the full experience, weekly deep-dives, interactive simulators, and clinical algorithms you can use on shift, come join us inside the VetEmCrit Academy.

    Episode 27: The Endothelial Glycocalyx — The Vascular Barrier We Keep Accidentally Punching
  5. Aug 14

    Episode 26: When Oxygen Becomes the Problem — Hyperoxia, Oxidative Injury, and Smarter Oxygen Targets

    The VetEmCrit Academy built for ER and ICU vets who want to grow, level up, and learn together: https://academy.vetemcrit.com/join In this episode, Dr. Lance Wheeler, DVM, DACVECC tackles the therapy we reach for most reflexively and titrate least carefully - oxygen, and what happens when the dose we give exceeds the dose the patient actually needs. Drawing from Chapter 8 of Small Animal Critical Care Medicine (3rd edition) by Duana McBride, and weaving in the 2023 New England Journal of Medicine review "Oxygen Therapy Part 2 - Indications and Toxicity" by Wemple et al., Lance reframes oxygen as a dose-dependent drug rather than a benign intervention and walks through a practical, structured framework for recognizing and avoiding oxidative harm: how 90 to 95 percent of oxygen is safely reduced to water while roughly 5 percent forms reactive oxygen and nitrogen species, the superoxide to hydrogen peroxide cascade and the Fenton, myeloperoxidase, and peroxynitrite pathways branching off it, how lipid peroxidation and DAMP release turn oxidative injury into a self-amplifying inflammatory cycle, and why the xanthine oxidoreductase system fires within 10 to 30 seconds of reperfusion. He then moves into the organ-by-organ consequences and the numbers that actually change bedside decisions, including absorption atelectasis and surfactant impairment in the lung, hyperoxic vasoconstriction and falling cardiac output, cerebral blood flow and traumatic brain injury, ventilated targets of SpO2 88 to 92 percent and PaO2 55 to 80 mm Hg, the FiO2 0.5 anchor below which clinical pulmonary oxygen toxicity is generally absent, hyperbaric oxygen therapy at 1.5 to 3.0 atmospheres absolute and its CNS toxicity risk, and where antioxidants genuinely fit. Along the way, he integrates the veterinary evidence, including 2021-2025 studies on hyperbaric oxygen adverse events across 2,792 treatment sessions, dietary antioxidants in dogs and cats, and N-acetylcysteine in Babesia gibsoni infection, and closes with a high-yield rapid-fire board review covering every key number worth memorizing. If you enjoy this episode and want the full experience, weekly deep-dives, interactive simulators, and clinical algorithms you can use on shift, come join us inside the VetEmCrit Academy.

    Episode 26: When Oxygen Becomes the Problem — Hyperoxia, Oxidative Injury, and Smarter Oxygen Targets

Ratings & Reviews

5
out of 5
6 Ratings

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Practical, evidence-based insights into veterinary emergency and critical care.

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