MOHIVATE

Mohi Sarawgee

Hosted by Dr. Mohi Sarawgee, a GP, MOHIvate is your doctor’s dose of heart and science — with just a touch of humour — because health and feeling good shouldn’t feel complicated. Each episode breaks down medicine and everyday science in a simple, thoughtful way, serving as a reminder that real health can still feel human. I hope you enjoy listening, learning, and carrying a little feel-good factor with you. Thank you for tuning in! Disclaimer: The information shared in this podcast is for educational and inspirational purposes only. It is not intended to be, and should not be taken as, personal medical advice, diagnosis, or treatment. Always seek the guidance of your own doctor or another qualified healthcare provider with any questions about your health, and never ignore or delay professional medical advice because of something you’ve heard here. The views expressed are my own and do not represent the views of any organizations or institutions I’m affiliated with.

  1. 2d ago

    35. Prickly Heat | When the Body Blocks What Needs to Flow

    Send us Fan Mail In this episode of Mohivate, Dr Mohi Sarawgee explores one of summer’s most familiar yet misunderstood conditions : Prickly Heat. A rash so common that most of us have experienced it, treated it, or complained about it without ever really understanding what is happening beneath the skin. The episode begins with the name. Prickly heat is medically known as miliaria, from the Latin word milium, meaning millet. The story travels from Roman physicians who first described it to British soldiers itching their way through India, Southeast Asia, and the Pacific, where the rash became such a military concern that researchers eventually studied it formally in tropical conditions. The science follows the sweat. From the remarkable efficiency of eccrine sweat glands to what happens when a sweat duct becomes blocked, Dr Mohi explores why prickly heat develops and how skin bacteria can turn a minor irritation into something far more uncomfortable. The three forms of miliaria : Crystallina, Rubra, and Profunda,  are explained clearly, including what each type means, who is most at risk, and when a doctor rather than a pharmacy is the right call. Practical guidance covers acclimatisation, clothing, skin care, prevention, and treatment, including why the answer has never been an enthusiastic application of powder. With clinical insight, personal reflection, humour, and a thread that runs beyond the skin itself, this episode asks a simple question: what happens when something designed to flow becomes blocked? Because sometimes the smallest discomforts are simply the body’s way of asking us to pay attention. This episode gives prickly heat the conversation it has always deserved. References: 1.Miliaria — StatPearls, National Library of Medicine (2024) https://www.ncbi.nlm.nih.gov/books/NBK537176/ 2.Heat Rash — Mayo Clinic https://www.mayoclinic.org/diseases-conditions/heat-rash/symptoms-causes/syc-20373276 3.Heat Rash — NHS https://www.nhs.uk/conditions/heat-rash-prickly-heat/ 4.Miliaria — DermNet NZ https://dermnetnz.org/topics/miliaria 5.Anhydrous Lanolin for Miliaria — Mayo Clinic Treatment Guide https://www.mayoclinic.org/diseases-conditions/heat-rash/diagnosis-treatment/drc-20373282 Just a gentle reminder: this episode is for information, education, and inspiration only. It’s not a substitute for your doctor’s advice. For any personal health concerns, always seek guidance from your doctor.

    24 min
  2. May 14

    34. Antihistamines, Pepcid & Menopause | Filling the Gaps Medicine Left Behind

    Send us Fan Mail In this episode of Mohivate, Dr Mohi Sarawgee explores one of the most talked about viral health trends of 2026 so far. Women combining an antihistamine and a heartburn tablet to manage menopause symptoms. And asks the question medicine should always ask first. What does the science actually say? The episode begins with histamine. Not the allergy molecule most people think they know, but a far more versatile chemical messenger with receptors in the gut, the heart, and the brain. From H1 to H2, from mast cells to the oestrogen-histamine feedback loop, this episode unpacks the biology behind the trend with clarity and warmth. It then explores the relationship between oestrogen and histamine in perimenopause, the role of the DAO enzyme, histamine intolerance as a distinct and underrecognised condition, and why mast cell activation syndrome is not the same as menopause, even when the symptoms overlap. The honest clinical verdict follows. Including why hot flushes are driven by the neurokinin B pathway and not histamine, what fezolinetant and elinzanetant are and why the UK was the first country in the world to approve the latter, and what HRT and non-hormonal options currently offer women who are struggling. With clinical insight, personal perspective, and a keen interest in perimenopause and menopause, this episode gives a viral trend the honest conversation it deserves.  REFERENCES 1.PCOS renamed to PMOS, The Lancet, 12 May 2026 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)00717-8/fulltext 2.CNN coverage of the viral menopause trend, May 2026 https://www.cnn.com/2026/05/05/health/menopause-hormones-antacids-antihistamines-wellness 3.Oestrogen and histamine bidirectional relationship https://pubmed.ncbi.nlm.nih.gov/22651948/ 4.Diamine oxidase and oestrogen regulation https://pubmed.ncbi.nlm.nih.gov/31234240/ 5.Histamine intolerance, clinical overview https://pubmed.ncbi.nlm.nih.gov/30239565/ 6.MCAS diagnostic criteria,  https://www.jacionline.org/article/S0091-6749(24)00569-4/fulltext 7.KNDy neurons and neurokinin B in menopausal hot flushes https://pubmed.ncbi.nlm.nih.gov/21253695/ 8.Fezolinetant, NICE supports NHS prescribing, March 2026 https://thebms.org.uk/2026/03/nice-supports-nhs-prescribing-of-fezolinetant/ 9.Elinzanetant, first global approval, MHRA, July 2025 https://www.gov.uk/government/news/mhra-approves-elinzanetant-to-treat-moderate-to-severe-vasomotor-symptoms-hot-flushes-caused-by-menopause 10.Cetirizine withdrawal rebound pruritus, FDA warning 2025 https://www.fda.gov/drugs/drug-safety-and-availability/fda-warns-about-serious- Just a gentle reminder: this episode is for information, education, and inspiration only. It’s not a substitute for your doctor’s advice. For any personal health concerns, always seek guidance from your doctor.

    29 min
  3. May 6

    33. The Long Way Home | Music, Memory & the Moments That Find Us

    Send us Fan Mail In this special episode of Mohivate, Dr Mohi Sarawgee brings together music, memory, and meaning in the podcast’s first original musical collaboration. At the heart of this episode is a beautiful piece of music titled The Long Way Home, created by Johan Sebastian Ledesma, who composes under the name Bragei.  What begins as a chance conversation on an ordinary street becomes something far more unexpected. A story of timing, recognition, and the kind of moments that seem to arrive without being planned, yet feel deeply aligned when they do. The episode moves through personal memory, from childhood road trips filled with music, to the people who shaped a lifelong relationship with sound, rhythm, and presence. It reflects on how music is not simply something we listen to, but something that holds memory, carries emotion, and connects us across time. Alongside this, Dr Mohi briefly explores what science understands about music and the brain. From its effects on stress, mood, and the nervous system, to the way it engages multiple regions of the brain at once, music is both deeply felt and biologically significant. At its heart, this episode is about the moments we do not plan. The ones that arrive through chance encounters, shared interests, and quiet attention. What some might call synchronicity, or serendipity. Moments that shape direction without announcement. The original piece The Long Way Home plays at the end of this episode, and will be available separately on YouTube for listeners who wish to return to it. With reflection, story, and collaboration, this episode offers something slightly different. A pause. A memory. And a reminder of the ways we find our way back, often without realising we were looking. References: 1. Music and the brain — stress, dopamine, and emotional response: Salimpoor, V.N. et al. (2011). Anatomically distinct dopamine release during anticipation and experience of peak emotion to music. Nature Neuroscience. https://www.nature.com/articles/nn.2726 2. Music, stress hormones, and the nervous system: Thoma, M.V. et al. (2013). The effect of music on the human stress response. PLOS ONE. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0070156 3. 3. Singing and wellbeing: Grape, C. et al. (2003). Does singing promote well-being? Integrative Physiological & Behavioral Science. https://link.springer.com/article/10.1007/BF02734261 Just a gentle reminder: this episode is for information, education, and inspiration only. It’s not a substitute for your doctor’s advice. For any personal health concerns, always seek guidance from your doctor.

    28 min
  4. Apr 29

    32. Screen Time in Children | Raising a Generation in a World Nobody Saw Coming

    Send us Fan Mail In this episode of Mohivate, Dr Mohi Sarawgee explores screen time in children: the first episode on MOHIVATE dedicated entirely to children, and an honest conversation about what is actually happening inside a child’s developing brain, and what the science is telling us in a world none of us were prepared for. The episode begins with context. From smartphones and tablets, to a pandemic that made screens the only classroom and playground available, to the first generation of children growing up alongside artificial intelligence as a daily presence. This is the world today’s parents are navigating. Without a guidebook, and largely without support. The science covers language development, attention and dopamine, sleep and melatonin, the video deficit effect in infants, and the childhood myopia epidemic, including why outdoor light, not eye drops, is the prescription. Age-specific guidance runs from birth through adolescence, including what the research says about social media, cyberbullying, and the teenage brain. Dr Mohi Sarawgee introduces the Three C’s framework — Content, Context, and Child — a practical lens for families navigating screen time at every age, alongside evidence-based anchors for sleep, eye health, and real life. With clinical insight, fifteen years of consulting rooms, and a doctor’s deep respect for every parent doing their absolute best, this episode gives screen time the conversation it deserves. REFERENCES 1. Screen Time and Early Childhood Development Frontiers in Developmental Psychology — Systematic Scoping Review (2025) https://www.frontiersin.org/journals/developmental-psychology/articles/10.3389/fdpys.2024.1439040/full 2. Screen Time and Sleep Hale & Guan — Screen Time and Sleep, Systematic Review, Sleep Medicine Reviews https://pmc.ncbi.nlm.nih.gov/articles/PMC4437561/ 3. Screen Time and Myopia Ha et al. — JAMA Network Open (February 2025) — 45 studies, 335,524 individuals https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2830598 4. Book by Jonathan Haidt The Anxious Generation — Research and Evidence Base https://www.anxiousgeneration.com/research/the-evidence 5. Adolescent Mental Health and Social Media — Dr. Jean Twenge Research publications and evidence base — Dr. Jean Twenge, San Diego State University https://www.jeantwenge.com/research/ 6. NHS Mental Health of Children and Young People in England (2023) NHS England Digital — most recent UK data https://digital.nhs.uk/data-and-information/publications/statistical/mental-health-of-children-and-young-people-in-england/2023-wave-4-follow-up 7. UK Government — Children’s Social Media Consultation (2026) GOV.UK National Consultation — Growing Up in the Online World https://www.gov.uk/government/consultations/growing-up-in-the-online-world-a-national-consultation 8. UK Government — Screen Use by Children Under Five (March 2026) Independent Expert Report — Early Years Screen Time Advisory Group https://assets.publishing.service.gov.uk/media/69c53daf4a06660f085442a7/EYSTAG_report.pdf Just a gentle reminder: this episode is for information, education, and inspiration only. It’s not a substitute for your doctor’s advice. For any personal health concerns, always seek guidance from your doctor.

    29 min
  5. Apr 23

    31. Magic Mushrooms & Psilocybin | Experience, Meaning & the Return of Psychedelics

    Send us Fan Mail In this episode of Mohivate, Dr Mohi Sarawgee explores psilocybin, the compound found in magic mushrooms, tracing its journey from ancient sacred ceremony to some of the most rigorous clinical research in psychiatry today. The episode begins where the science begins. With language. When neuroscientists at Johns Hopkins first documented what psilocybin did to the human brain, they had to invent entirely new words to describe it. Ego dissolution. Oceanic boundlessness. Mystical type experience score. This episode explores why those words matter clinically, and what the Default Mode Network has to do with depression, addiction, and the way the brain finds its way back to itself. From Richard Nixon’s 1970 decision to classify psilocybin as a Schedule 1 drug, freezing decades of promising research, to landmark clinical trials, this episode covers the full story honestly. The science on terminal cancer anxiety, treatment resistant depression, addiction, and microdosing is examined carefully - where the evidence is strong, where it is thin, and what regulatory bodies worldwide are now saying. With clinical insight, personal perspective, and a thread that begins with Roald Dahl, this is a conversation about what happens when science refuses to stay buried. References 1.The 2006 Johns Hopkins Paper — The One That Changed Everything https://pubmed.ncbi.nlm.nih.gov/16826400/ 2.Psilocybin in Terminal Cancer Patients — 2016 Landmark Study https://pmc.ncbi.nlm.nih.gov/articles/PMC5367557/ 3.Psilocybin vs Escitalopram — NEJM 2021 https://www.nejm.org/doi/full/10.1056/NEJMoa2032994 4.Psilocybin and Smoking Cessation — The 80% Study https://pmc.ncbi.nlm.nih.gov/articles/PMC4286320/ 5.Default Mode Network and Depression — Key Neuroscience Paper https://pubmed.ncbi.nlm.nih.gov/24567117/ 6.Psilocybin and the Default Mode Network — Brain Imaging https://www.pnas.org/doi/10.1073/pnas.1119598109 7.Microdosing — James Fadiman Book Reference https://www.amazon.com/Psychedelic-Explorers-Guide-Therapeutic-Journeys/dp/1594774021 8.Microdosing Blinded Trials — Placebo Effects https://elifesciences.org/articles/62878 9.Psilocybin Safety Profile — The Lancet https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(10)61462-6/fulltext 10.Nixon, Ehrlichman and the War on Drugs https://edition.cnn.com/2016/03/23/politics/john-ehrlichman-nixon-drug-war-blacks-hippie/index.html 11.Australia Approves Psilocybin — TGA 2023 https://www.tga.gov.au/news/media-releases/tga-approves-mdma-and-psilocybin-use-ptsd-and-depression-australia-first 12.FDA Breakthrough Therapy Designation for Psilocybin https://compasspathways.com/compass-pathways-receives-fda-breakthrough-therapy-designation-for-psilocybin-therapy-for-treatment-resistant-depression/ 13.UK Innovative Licensing and Access Pathway — ILAP https://ir.compasspathways.com/News–Events-/news/news-details/2025/Compass-Pathways-Successfully-Achieves-Primary-Endpoint-in-First-Phase-3-Trial-Evaluating-COMP360-Psilocybin-for-Treatment-Resistant-Depression/default.aspx 14.Yale Program for Psychedelic Science https://medicine.yale.edu/psychiatry/research/clinics-and-programs/psychedelic/ 15.Johns Hopkins Centre for Psychedelic and Consciousness Research https://www.hopkinsmedicine.org/psychiatry/research/psychedelics-research 16.Imperial College London Centre for Psychedelic Research https://www.imperial.ac.uk/psychedelic-research-centre 17.R. Gordon Wasson — Seeking the Magic Mushroom, Life Magazine 1957 https://www.imaginaria.org/wasson/life.htm 18.Psilocybin Drug Interactions — Lithium and SSRIs https://pubmed.ncbi.nlm.nih.gov/18593734/ Just a gentle reminder: this episode is for information, education, and inspiration only. It’s not a substitute for your doctor’s advice. For any personal health concerns, always seek guidance from your doctor.

    28 min
  6. Apr 15

    30. Berberine | Promise, Pitfalls & Perspective

    Send us Fan Mail In this episode of Mohivate, Dr Mohi Sarawgee explores berberine, one of the most talked about metabolic supplements right now, bringing clarity to a conversation often shaped more by social media than by science. Berberine is a naturally occurring alkaloid with thousands of years of history in Ayurvedic and traditional Chinese medicine. This episode traces how it moved from gut medicine to metabolic science, unpacking the mechanisms behind its effects on blood sugar, insulin resistance, lipid metabolism, and the PCSK9 pathway, the same cholesterol target that billion dollar injectable medications were developed to address. The episode examines the clinical evidence honestly, including the landmark head to head comparison with metformin, the 2025 meta-analysis data, and the real limitations of the current evidence base. It covers who berberine is actually used in, what the safety and interaction profile looks like, and why formulation and dose matter more than most supplement labels suggest. With clinical insight and a GP’s perspective, this episode gives berberine the conversation it deserves. REFERENCES 1. Berberine and Metabolic Syndrome — 2025 Systematic Review and Meta-Analysis https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1572197/full 2. Berberine Health Outcomes — Overview of 54 Systematic Reviews https://link.springer.com/article/10.1186/s12906-025-04872-4 3. Berberine vs Metformin — Head to Head Trial. Zhang Y et al.  https://academic.oup.com/jcem/article/93/7/2559/2598177 4. Berberine as a Novel Cholesterol Lowering Drug — PCSK9 and LDL Receptor Mechanism Kong W et al. Nature Medicine, 2004 https://www.nature.com/articles/nm1135 5. Berberine PCSK9 Inhibition — Review Berberine: Ins and outs of a nature-made PCSK9 inhibitor https://www.excli.de/excli/article/view/5234 6. Berberine Bioavailability and Gut Microbiome https://www.mdpi.com/1424-8247/18/2/193 7. Berberine and NAFLD — 2024 Meta-Analysis https://pubmed.ncbi.nlm.nih.gov 8. Dihydroberberine vs Standard Berberine HCl — 2021 RCT https://pubmed.ncbi.nlm.nih.gov/35010998/ 9. Berberine and PCOS — 2024 Meta-Analysis https://pubmed.ncbi.nlm.nih.gov 10. Semaglutide Cardiovascular Outcomes — NEJM https://www.nejm.org/doi/full/10.1056/NEJMoa1607141 11. Semaglutide Weight Loss — STEP Trial Wilding JPH et al. New England Journal of Medicine, 2021 https://www.nejm.org/doi/full/10.1056/NEJMoa2032183 12. AMPK as Metabolic Master Switch — Review Hardie DG.  https://onlinelibrary.wiley.com/doi/10.1111/joim.12268 13. Berberine Drug Interactions — CYP450 Guo Y et al. https://pubmed.ncbi.nlm.nih.gov/21987089/ 14. Berberine Contraindication in Pregnancy Liu W et al. Available via PubMed safety data: https://pubmed.ncbi.nlm.nih.gov Just a gentle reminder: this episode is for information, education, and inspiration only. It’s not a substitute for your doctor’s advice. For any personal health concerns, always seek guidance from your doctor.

    26 min
  7. Apr 9

    29. Continuous Glucose Monitoring | Data, Patterns & Beyond the Hype

    Send us Fan Mail In this episode of Mohivate, Dr Mohi Sarawgee explores continuous glucose monitoring through the lens of metabolic health, bringing clarity to one of the most talked about and most misunderstood tools in modern wellness. The CGM is everywhere. On social media arms, in wellness programmes, in dinner party conversations. But what does it actually measure? What is the science genuinely telling us? And who actually needs one? This episode covers how CGMs work, what glucose patterns really mean, the science of glycaemic index and glycaemic load, why two people can eat the same meal and have completely different responses, and what advanced glycation end products tell us about long term health. It explores how to read your own data, what HbA1c misses, and who should and should not consider wearing one, with honest clinical guidance and no agenda. Grounded in science, personal experience, and a mild voluntary obsession with data, this is a warm, honest and genuinely useful conversation about glucose, metabolic health, and what your body has been trying to show you all along. References: 1. Glycaemic Index and Glycaemic Load — Food Reference University of Sydney International GI Database. Search GI and GL values for thousands of foods: https://glycemicindex.com/gi-search/ 2. Individual Variation in Glucose Response — The PREDICT Study Berry SE et al. Human postprandial responses to food and potential for precision nutrition. Nature Medicine. 2020;26:964–973. https://www.nature.com/articles/s41591-020-0934-0 PubMed: https://pubmed.ncbi.nlm.nih.gov/32528151/ 3. The 42 Factors — Further Reading The PREDICT study machine learning model used 42 individual factors to predict glucose response. For a detailed accessible breakdown of factors influencing blood glucose, see also: https://diatribe.org/diabetes-management/42-factors-affect-blood-glucose-surprising-update 4. Post-Meal Walking — 10 Minutes Immediately After Eating Hashimoto K et al. Positive impact of a 10-min walk immediately after glucose intake on postprandial glucose levels. Scientific Reports. 2025. https://www.nature.com/articles/s41598-025-07312-y Supporting systematic review: Engeroff T et al. After Dinner Rest a While, After Supper Walk a Mile? Sports Medicine. 2023;53(4):849–869. https://pubmed.ncbi.nlm.nih.gov/36715875/ 5. Soleus Pushup Pilot Study Elek D et al. The Efficacy of Soleus Push-Up in Individuals with Prediabetes: A Pilot Study. Sports (Basel). 2025;13(3):81. https://pmc.ncbi.nlm.nih.gov/articles/PMC11946342/ Just a gentle reminder: this episode is for information, education, and inspiration only. It’s not a substitute for your doctor’s advice. For any personal health concerns, always seek guidance from your doctor.

    23 min
  8. Apr 1

    28. Hay Fever | A Case Of Mistaken Identity

    Send us Fan Mail In this episode of Mohivate, Dr Mohi Sarawgee explores hay fever through the lens of immunology, bringing clarity to one of the most common and often underestimated conditions worldwide. Hay fever, or allergic rhinitis, is an immune response shaped by genetics, environment, and a system designed to protect you, reacting to something that was never meant to be a threat. Beneath the sneezing and the itchy eyes is a story about your immune system making a spectacular case of mistaken identity. This episode covers how sensitisation works, the three overlapping pollen seasons, the hidden food connection most people never realise, the relationship between hay fever and asthma, and why hay fever is getting worse globally, and what that means for the hundreds of millions of people living with it. Practical, clinically grounded, and with some tips that may genuinely change how you manage this season. References: 1. Global prevalence of allergic rhinitis:  Allergic Rhinitis: A Clinical and Pathophysiological Overview. Frontiers in Medicine, 2022. https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.874114/full 2. Pollen seasons lengthening. Anthropogenic climate change is worsening North American pollen seasons. Proceedings of the National Academy of Sciences, 2021. https://www.pnas.org/doi/10.1073/pnas.2013284118 3. UK pollen season. Climate Central — Pollen Season and Climate Change. https://www.climatecentral.org/climate-matters/pollen-season-climate-change 4. United airway disease : hay fever and asthma connection. United Airway Disease: Current Perspectives. Journal of Asthma and Allergy, PMC. https://pmc.ncbi.nlm.nih.gov/articles/PMC4872272/ 5. Oral Allergy Syndrome. Stanford Health Care. https://stanfordhealthcare.org/content/dam/SHC/clinics/menlo-medical-clinic/docs/Allergy/Oral%20Allergy%20Syndrome.pdf Just a gentle reminder: this episode is for information, education, and inspiration only. It’s not a substitute for your doctor’s advice. For any personal health concerns, always seek guidance from your doctor.

    24 min

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About

Hosted by Dr. Mohi Sarawgee, a GP, MOHIvate is your doctor’s dose of heart and science — with just a touch of humour — because health and feeling good shouldn’t feel complicated. Each episode breaks down medicine and everyday science in a simple, thoughtful way, serving as a reminder that real health can still feel human. I hope you enjoy listening, learning, and carrying a little feel-good factor with you. Thank you for tuning in! Disclaimer: The information shared in this podcast is for educational and inspirational purposes only. It is not intended to be, and should not be taken as, personal medical advice, diagnosis, or treatment. Always seek the guidance of your own doctor or another qualified healthcare provider with any questions about your health, and never ignore or delay professional medical advice because of something you’ve heard here. The views expressed are my own and do not represent the views of any organizations or institutions I’m affiliated with.