Dr. Busti will explain gallbladder anatomy and gallbladder physiology, connecting bile flow and gallstones to the clinical findings healthcare professionals encounter in practice. Follow bile from hepatic production through gallbladder storage, concentration, and meal-triggered release. Learn how cholecystokinin coordinates delivery, how the cystic duct connects the gallbladder to the common bile duct, and why stone location changes the clinical consequences. Apply this framework to cholelithiasis, cholecystitis, choledocholithiasis, cholangitis, and gallstone pancreatitis. The lecture connects structure and function to bedside findings and explains why stones alone do not establish acute gallbladder inflammation. Compare the questions answered by gallbladder ultrasound, MRCP, and a HIDA scan, including the limitations of interpreting gallbladder ejection fraction. You will also learn why bile production continues after cholecystectomy. Anatomical illustrations, ultrasound examples, and a rotating 3D MRCP reconstruction help connect the concepts to clinical interpretation. When we understand the why, we improve the how. 👉 Get more with a free membership at https://www.thisiswhy.health/ Access free downloads from our videos Access deep-dive content from Dr. Busti Organize content via playlists & collections Join live Q&A Receive member newsletters Coupons & discounts for exam prep resources Chapter Table of Contents 00:00 - Introduction 03:30 - Bile Production & the Biliary System 07:30 - Gallbladder Anatomy & Structure 12:00 - How the Gallbladder Stores & Concentrates Bile 16:30 - Bile Release, CCK, & the Sphincter of Oddi 21:00 - Gallstones & Biliary Obstruction 26:00 - Gallbladder Disorders & Clinical Symptoms 31:00 - Ultrasound, HIDA Scan, MRCP, & ERCP 35:48 - Why You Can Live Without a Gallbladder 37:29 - Six Key Takeaways & Clinical Applications 👍 If this helped you, please like, subscribe, and share it with a classmate or colleague. That will help this channel continue producing free, high-yield medical education content. 🔔 Don’t forget to turn on notifications so you don’t miss upcoming lectures in pharmacology, medical rounds, and more! #Gallbladder #GallbladderAnatomy #GallbladderPhysiology #Gallstones #DrBusti Speaker: Anthony Busti, MD, PharmD, MSc, FAHA, FNLA, is a licensed healthcare professional and medical educator with over 30 years of experience in clinical practice and academic teaching. He has trained and practiced as a nurse, pharmacist, and physician, bringing a uniquely comprehensive perspective to patient care and medical education. Dr. Busti is dedicated to advancing evidence-based medicine and helping clinicians understand the underlying “why” behind clinical decisions to improve patient outcomes. About This Channel: This content is created by Anthony Busti, MD, PharmD, MSc, FAHA, FNLA, a board-certified physician with training at Johns Hopkins School of Medicine and University of Oxford and a medical educator for healthcare professionals and students. All material is based on current medical literature and evidence-based guidelines aligned with the principles of evidence-based medicine (EBM) and Evidence-Based Healthcare (EBHC). Disclaimer: This content is for educational purposes only and is not medical advice. It does not replace individualized evaluation, diagnosis, or treatment. Always seek the advice of a qualified health provider with questions about a medical condition and never delay care because of educational content.