Out of Office

Lightspeed

Out of Office is a new podcast from Lightspeed for people who build, create, and think about what’s next. No studio. No Zoom. No filter. Host Michael Mignano, Partner at Lightspeed and Co-Founder of Anchor, steps out into the real world to talk with the most interesting minds in AI, tech, and media. We’re leaving the office behind, hanging out, asking real questions, and letting the conversations go wherever they lead.

Episodes

  1. Nikita Bier is Out Of Office

    FEB 10

    Nikita Bier is Out Of Office

    In this episode of Out of Office, Lightspeed partner Michael Mignano sits down with X’s head of product, Nikita Bier. They met up near Nikita’s hometown in the South Bay of Los Angeles, where they unpack the unlikely path that took him from an internet-obsessed kid to helping steer one of the world’s most influential platforms. Over tacos on the pier, Nikita explains how a DM from Elon Musk turned into a job offer, how his many years of prolific posting on X have prepared him for the role, and how his small team is trying to keep up growth on a 20-year-old platform. Nikita shares the challenges building products in public view, how sentiment from X users can flip on a dime, and why X will always prioritize free speech. Episode Chapters:  00:00 No Silver Bullet to Growth00:19  X as a Financial Network01:25 Welcome to South Bay01:56 Growing Up in Redondo Beach: Internet Adventures02:52 From Hacking to Growth Hacking06:57 Joining X: The Journey and Challenges09:14 Restarting X’s Growth and Product Development15:44 The Role of a Product Head at X29:13 Balancing Free Speech and Authenticity on X34:58 The Future of X: AI, Links, and User Engagement37:22 Solving Engagement Issues on X40:42 Working with Elon Musk50:13 Building Viral Apps: TBH and Gas01:02:35 Consulting and Angel Investing01:10:09 AI’s Impact on App Development01:12:49 X Diagnosed My Disease01:14:14 The Pier and See You on X Stay in touch: Website: ⁠⁠⁠https://www.lsvp.com⁠⁠⁠ X: ⁠⁠⁠https://x.com/lightspeedvp  ⁠⁠⁠ LinkedIn: ⁠⁠⁠https://www.linkedin.com/company/lightspeed-venture-partners/⁠⁠⁠ Instagram: ⁠⁠⁠https://www.instagram.com/lightspeed/⁠⁠⁠ Subscribe on your favorite podcast app: https:/⁠⁠⁠/linktr.ee/ooolightspeed⁠⁠⁠ Follow Michael: X:  ⁠⁠⁠https://x.com/mignano⁠⁠⁠ TikTok:  ⁠⁠⁠https://www.tiktok.com/@michael.mignano⁠⁠⁠ LinkedIn:  ⁠⁠⁠https://www.linkedin.com/in/mignano/ ⁠⁠ The content here does not constitute tax, legal, business or investment advice or an offer to provide such advice, should not be construed as advocating the purchase or sale of any security or investment or a recommendation of any company, and is not an offer, or solicitation of an offer, for the purchase or sale of any security or investment product. For more details please see ⁠⁠lsvp.com/legal⁠⁠. Out of Office is produced by Lightspeed in partnership with⁠ Pod People.

    1h 15m
  2. Garry Tan is Out Of Office

    JAN 22

    Garry Tan is Out Of Office

    In this episode of Out of Office, Lightspeed Partner Michael Mignano joins Y Combinator CEO Garry Tan for a walk through his home turf: San Francisco. Garry reflects on growing up in the Bay Area, learning to code as a teenager, and how those early experiences led him from founder to investor to one of the most influential figures in tech. The conversation spans seed investing, Y Combinator’s evolving model, and why Garry believes abundance, resilience, and taste matter more than ever in the age of AI. They also dive into Garry’s outspoken involvement in San Francisco politics and his investment in shaping the city, from public safety and education to housing and self-driving cars, and what it really takes to move the needle locally. Michael gets to know the real Garry Tan as they check out some of his favorite local spots. Along the way, Garry opens up about faith, community, and why bringing people together offline has become central to his life. Episode Chapters 00:00 Introduction to San Francisco's Tech Scene 01:04 Meeting Gary Tan: A Journey Through San Francisco 02:22 Gary's Early Days in Tech 04:09 The Impact of San Francisco on Tech Aspirations 06:16 Political Awakening and Local Involvement 18:38 Saunagate and Garry’s Personal Life 22:36 Relationship to Faith and Technology 30:32 Reflections and Future Aspirations 31:05 Rejection and Resilience in YC Applications 31:32 Handling Public Criticism and Rejection 32:13 The Journey of Building a Startup 34:06 Transition from Initialized to YC 35:59 YC's Investment Strategy and Success 37:52 Changes and Future of YC 49:32 Community Involvement and Local Impact 50:45 Future of San Francisco and Tech 52:40 Future of YC and Venture Capital 56:13 Personal Insights at the Bar 56:31 Conclusion and Farewell Stay in touch: Website: ⁠⁠https://www.lsvp.com⁠⁠ X: ⁠⁠https://x.com/lightspeedvp  ⁠⁠ LinkedIn: ⁠⁠https://www.linkedin.com/company/lightspeed-venture-partners/⁠⁠ Instagram: ⁠⁠https://www.instagram.com/lightspeed/⁠⁠ Subscribe on your favorite podcast app: https:/⁠⁠/linktr.ee/ooolightspeed⁠⁠ Follow Michael: X:  ⁠⁠https://x.com/mignano⁠⁠ TikTok:  ⁠⁠https://www.tiktok.com/@michael.mignano⁠⁠ LinkedIn:  ⁠⁠https://www.linkedin.com/in/mignano/ ⁠ The content here does not constitute tax, legal, business or investment advice or an offer to provide such advice, should not be construed as advocating the purchase or sale of any security or investment or a recommendation of any company, and is not an offer, or solicitation of an offer, for the purchase or sale of any security or investment product. For more details please see ⁠lsvp.com/legal⁠. Out of Office is produced by Lightspeed in partnership with Pod People.

    57 min
  3. Semil Shah is Out Of Office

    12/04/2025

    Semil Shah is Out Of Office

    In this episode of Out of Office, Michael Mignano meets up with renowned seed investor and friend Semil Shah in New York City to unpack what it really means to build and invest during a volatile moment in tech. Together they explore whether any startup category is safe now that OpenAI is shipping hit apps like Sora, and how generative media is reshaping everything from product launches to social networks. They dive into the coming saturation of launch videos, the collapse in cost of high-quality creative, and why founders will soon need entirely new tactics to stand out. They get into why seed investing feels increasingly under pressure from accelerators and megafunds, and how prediction markets like Polymarket might eventually disrupt venture capital itself.  Speaking in front of an audience of friends and colleagues at Joe’s Pub in New York City, The conversation veers into sports betting culture, the NBA scandal, and the broader rise of new markets. Despite the chaos, Semil explains why he still believes seed investing is the best job in the world and why the most exceptional founders will always find a path.  Episode Chapters:  0:00 – Cold open: launch videos and why everything looks the same 1:30 – New podcast formats 2:30 – The launch video arms race 6:30 – Generative media & the true cost collapse of video 10:59 – Is any app category safe from OpenAI? 13:10 – Sam Altman & execution 18:00 – How consumers actually use AI 20:01 – What Sora means for social media 24:09 – Seed investors and the “AI wave” 29:24 – Live at Joe’s Pub: Scott Rogowsky intro 30:39 – Sports and the betting market 35:40 – PolyMarket and prediction markets 43:30 – Why seed is under attack 47:20 – People vs. markets 52:20 – AI and category risk 59:00 – Signs of an AI bubble 1:06:03 – The AI roll-up craze 1:11:08 – Audience Q&A: prediction market manipulation and career pride Stay in touch: Website: ⁠https://www.lsvp.com⁠ X: ⁠https://x.com/lightspeedvp  ⁠ LinkedIn: ⁠https://www.linkedin.com/company/lightspeed-venture-partners/⁠ Instagram: ⁠https://www.instagram.com/lightspeed/⁠ Subscribe on your favorite podcast app: https:/⁠/linktr.ee/ooolightspeed⁠ Follow Michael: X:  ⁠https://x.com/mignano⁠ TikTok:  ⁠https://www.tiktok.com/@michael.mignano⁠ LinkedIn:  ⁠https://www.linkedin.com/in/mignano/  The content here does not constitute tax, legal, business or investment advice or an offer to provide such advice, should not be construed as advocating the purchase or sale of any security or investment or a recommendation of any company, and is not an offer, or solicitation of an offer, for the purchase or sale of any security or investment product. For more details please see lsvp.com/legal. Out of Office is produced by Lightspeed in partnership with⁠ Pod People.

    1h 20m
  4. Casey Neistat is Out of Office

    11/12/2025

    Casey Neistat is Out of Office

    On this inaugural episode of Out of Office, Lightspeed Partner Michael Mignano roams SoHo and Chinatown with filmmaker and YouTube icon Casey Neistat to explore how New York City became his lifelong muse—and how AI is about to reshape filmmaking. They explore Casey’s journey from camcorders and point-and-shoots to phones and drones, and debate why imperfect, human choices often beat pristine, over-engineered images, at least for now. Over rice and roast pork, they dig into authenticity vs. automation and what happens when algorithms can flood the zone with infinite, watchable content. They also look ahead to the “post-phone” era, when everyone has wearables, glasses, and single-purpose devices, and what that will mean for attention, creativity, and future generations. Chapters: 0:00 Welcome to Out of Office 4:22 Tools, Authenticity & The Evolution of Filmmaking 11:53 AI as a Filmmaking Tool 14:11 The AI Tidal Wave & The Future of Content 20:01 Movies, Theaters and the Attention Economy 26:45 The Business of Video and AI Monetization 30:29 How AI Changes Creator Economics 35:16 What Happens to Big Creators Like MrBeast? 41:19 Peak Phone and the Next Wave of Devices43:12 Beme, Realness & The Lost Internet 47:23 From Startup to CNN & Lessons from the Acquisition 54:54 Can Media & News Survive AI? 59:05 Meta Glasses vs Vision Pro — The Next Interface 1:04:11 Parenting & Raising Kids in a Tech World 1:08:45 Casey’s Final Reflection: Purpose Over Success ABOUT OUT OF OFFICE PODCAST: Out of Office is a new podcast from Lightspeed for people who build, create, and think about what’s next. No studio. No Zoom. No filter. Host Michael Mignano, Partner at Lightspeed and Co-Founder of Anchor, steps out into the real world to talk with the most interesting minds in AI, tech, and media. We’re leaving the office behind, hanging out, asking real questions, and letting the conversations go wherever they lead. Stay In Touch: Website: http://www.lsvp.com X: https://x.com/lightspeedvp   LinkedIn: https://www.linkedin.com/company/lightspeed-venture-partners/ Instagram: https://www.instagram.com/lightspeed/ Subscribe on your favorite podcast app: https://linktr.ee/ooolightspeed Follow Michael: X:  https://x.com/mignano TikTok:  https://www.tiktok.com/@michael.mignano LinkedIn:  https://www.linkedin.com/in/mignano/  DISCLAIMER: The content here does not constitute tax, legal, business or investment advice or an offer to provide such advice, should not be construed as advocating the purchase or sale of any security or investment or a recommendation of any company, and is not an offer, or solicitation of an offer, for the purchase or sale of any security or investment product. The views expressed by our guests do not necessarily represent the views of Lightspeed. For more details please see https://www.lsvp.com/legal. Out of Office is produced by Lightspeed in partnership with⁠ Pod People.

    1h 14m

Ratings & Reviews

3
out of 5
2 Ratings

About

Out of Office is a new podcast from Lightspeed for people who build, create, and think about what’s next. No studio. No Zoom. No filter. Host Michael Mignano, Partner at Lightspeed and Co-Founder of Anchor, steps out into the real world to talk with the most interesting minds in AI, tech, and media. We’re leaving the office behind, hanging out, asking real questions, and letting the conversations go wherever they lead.

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