The Long-evity Game Podcast

Michael Ward, AGACNP-BC

Ready to outsmart Father Time with science, sweat, and a few laughs? Join Michael, a medical pro who trades lab coats for lively conversations, as he dives into the hottest trends in men’s health and beyond. You’ll get up-to-date insights on hormone optimization, muscle building, nutrition, longevity science, and the real stories behind the headlines. Whether you’re hitting midlife with gusto or just looking to maximize your health IQ, this show serves men and women who want to stay in peak form – body and brain.

  1. 5D AGO

    Ep. 17 | The Future of Longevity: Why Fat Loss Isn’t Enough Anymore

    In this episode of the Longevity Game Podcast, Michael Ward explores the evolving landscape of longevity science, emphasizing the importance of preserving biological systems rather than merely focusing on weight loss or living longer. He discusses the significance of synchronization among various biological systems, the role of mitochondria in aging, and the necessity of muscle preservation for longevity. The conversation also highlights the potential of new compounds like alpha-ketoglutarate and GLP-1 medications, while stressing that exercise remains irreplaceable in promoting health and longevity. The episode concludes with actionable steps listeners can take to enhance their longevity journey.Takeaways-Losing weight is no longer the primary goal; preserving biological systems is.-Longevity science is shifting towards understanding biological synchronization.-Communication between bodily systems is crucial for longevity.-Mitochondrial health plays a significant role in aging.-Muscle preservation is essential for metabolic health and longevity.-GLP-1 medications can aid in weight loss but should be combined with muscle preservation efforts.-Grip strength is a strong predictor of overall health and longevity.-Exercise mimetics are being researched but cannot replace the benefits of actual exercise.-Maintaining metabolic flexibility is key to longevity.-Actionable steps include lifting weights, prioritizing protein, and ensuring consistent sleep.For Contact, Sponsorship, Press, Support:*Have a question or concern about a topic or particular episode?Hello@TheLongevityGamePodcast.com*Interested in being a guest on the show? BeAguest@TheLongevityGamePodcast.com*Interested in supporting/sponsoring the show?Sponsors@TheLongevityGamePodcast.comKeywords#longevity, #biologicalsystems, #mitochondrialhealth, #musclepreservation, #GLP-1 medications, #exercise #mimetics, #aging, #healthspan, #metabolicflexibility, #alphaketoglutarate

    39 min
  2. JAN 27

    Ep.16 | Beyond Weight Loss: Epigenetic Age, Muscle Preservation & The Future of Performance Medicine

    In this episode of the Longevity Game Podcast, Michael Ward discusses the evolving landscape of longevity medicine, emphasizing the importance of muscle, mitochondria, and metabolic health. He explores the significance of epigenetic age, the role of resistance training, and the impact of wearable technology on health monitoring. The conversation also highlights the importance of protein intake and introduces the peptide GHKCU, discussing its benefits and limitations. The episode concludes with key takeaways on optimizing health and longevity.Takeaways-Losing weight alone may not equate to better health.-Muscle is recognized as a longevity organ.-Epigenetic age can be modified through lifestyle changes.-Resistance training is crucial for maintaining muscle mass.-Wearable technology can help track health metrics effectively.-Mitochondria play a vital role in metabolic health.-Protein intake is essential for muscle protein synthesis.-Zone two cardio is beneficial for fat loss and endurance.-Peptides can support health but should not replace lifestyle changes.-Health span is as important as lifespan. For Contact, Sponsorship, Press, Support:*Have a question or concern about a topic or particular episode?Hello@TheLongevityGamePodcast.com*Interested in being a guest on the show? BeAguest@TheLongevityGamePodcast.com*Interested in supporting/sponsoring the show?Sponsors@TheLongevityGamePodcast.com#longevity, #healthspan, #epigeneticage, #resistancetraining, #wearabletechnology, #mitochondria, #musclehealth, #peptides, #metabolichealth, #healthoptimization

    42 min
  3. JAN 20

    Ep. 15 | The Secret to Longevity-Delaying Decline

    In this episode of the Longevity Game Podcast, Michael Ward delves into the concept of aging, emphasizing that longevity is not merely about extending life but about maintaining quality and capability as we age. He highlights the common misconception that aging is solely about visible signs like wrinkles, when in fact, decline begins much earlier, affecting muscle mass, hormones, and metabolic health. Michael stresses the importance of proactive measures to delay this decline, advocating for a focus on muscle preservation, mitochondrial health, and overall metabolic wellness. He outlines four key strategies to combat aging: preserving muscle, enhancing mitochondrial function, controlling inflammation, and using health tools strategically rather than emotionally.-Longevity is about delaying decline, not just adding years.-Preserving muscle is crucial for maintaining quality of life.-Mitochondrial health is essential for energy and recovery.-Chronic inflammation accelerates aging and should be controlled.-Tools like peptides should be used intentionally, not recklessly.For Contact, Sponsorship, Press, Support:*Have a question or concern about a topic or particular episode?Hello@TheLongevityGamePodcast.com*Interested in being a guest on the show? BeAguest@TheLongevityGamePodcast.com*Interested in supporting/sponsoring the show?Sponsors@TheLongevityGamePodcast.com#longevity, #aging, #muscle, #mitochondrialhealth, #metabolic #wellness, #health strategies, #decline #prevention, #peptides, #insulinresistance, #qualityoflife

    33 min
  4. JAN 10

    Ep. 14 | Unlocking Longevity: strength, muscle, and hormones after 40

    In this episode of the Longevity Game podcast, Michael Ward discusses the importance of longevity and performance medicine, particularly for those over 40. He emphasizes the significance of muscle strength and resistance training in combating the effects of aging, as well as the critical role of nutrition and hormonal optimization. The episode also features a spotlight on the peptide GHK-Cu, known for its regenerative properties, and addresses the responsibility of bodybuilders in maintaining health while pursuing physique goals. Takeaways -Aging is a gradual process that can be managed. -Sarcopenia, or age-related muscle loss, begins in our thirties. -Resistance training is essential for maintaining muscle mass after 40. -Higher muscle mass is associated with lower all-cause mortality. -Nutrition, especially protein intake, is crucial for muscle health. -Annual lab testing is important for preventive health care. -GHK-Cu peptide aids in tissue repair and regeneration. -Bodybuilding should prioritize health and safety over performance enhancement. -Consistent strength training can improve overall quality of life. -Longevity is about being strong enough to enjoy life. For Contact, Sponsorship, Press, Support: *Have a question or concern about a topic or particular episode?Hello@TheLongevityGamePodcast.com *Interested in being a guest on the show? BeAguest@TheLongevityGamePodcast.com *Interested in supporting/sponsoring the show?Sponsors@TheLongevityGamePodcast.com #longevity, #performance #medicine, #hormone #optimization, #resistance #training, #nutrition, #aging, #peptides, #muscle #health, #strength #training, #healthresponsibility

    38 min
  5. 12/26/2025

    Ep 13 | Longevity, Mitochondria & Meaning: The Science of a Healthier New Year

    In this episode of the Longevity Game show, Michael discusses the intersection of holiday festivities and longevity science. He emphasizes the importance of social connections during the holiday season while introducing new research on mitochondria and their role in aging. The episode also features a segment on peptides, particularly MOTC, and concludes with practical advice on sleep, nutrition, movement, and the significance of purpose in enhancing longevity. Takeaways -Social connections are crucial for longevity. -Mitochondria play a key role in energy production and aging. -Improving mitochondrial efficiency can extend lifespan. -MOTs-C is a peptide that signals metabolic stress adaptation. -Sleep, nutrition, and movement are essential for longevity. -Longevity is a system-based approach, not just supplements. -Gratitude and purpose contribute to better health outcomes. -Mitochondrial health is linked to metabolic disease risk. -Avoid mixing sugar and alcohol for better health. -Longevity strategies are becoming mainstream. For Contact, Sponsorship, Press, Support: *Have a question or concern about a topic or particular episode?Hello@TheLongevityGamePodcast.com *Interested in being a guest on the show? BeAguest@TheLongevityGamePodcast.com *Interested in supporting/sponsoring the show?Sponsors@TheLongevityGamePodcast.com #longevity, #mitochondria, #peptides, #healthoptimization, #aging, #MOTSC #nutrition, #sleep, #movement, #purpose #Christmas2025 #TheLongevityGamePodcast

    26 min
  6. 12/12/2025

    Ep. 12 | Hormones, Longevity, and the Future of Weight Loss: This Week’s Breakthroughs

    In this episode, Michael Ward discusses the latest advancements in hormone optimization, focusing on both women's and men's health. He highlights the importance of hormone replacement therapy (HRT) for women, particularly during menopause, and the recent FDA recommendations for testosterone therapy in men. The conversation also covers groundbreaking weight loss medications, the rise of peptides, and the significance of mitochondrial health in longevity. The episode concludes with insights into the evolving landscape of longevity science and its implications for health and wellness.Takeaways -Women's hormone health is finally getting the attention it deserves. -Transdermal estradiol is the gold standard for safety in hormone therapy. -Men's testosterone therapy is becoming more accessible due to new FDA recommendations. -Weight loss medications like Reta-Trutide show unprecedented results. -Peptides are powerful but should be treated with caution and medical oversight. -Mitochondrial health is crucial for longevity and can be improved through exercise and hormone optimization. -The myth that hormone replacement therapy is dangerous is being debunked by new research. -Hormone optimization can enhance the effectiveness of weight loss medications. -The landscape of longevity science is rapidly evolving with new research and therapies. -Understanding the role of hormones in metabolic health is essential for both men and women. For Contact, Sponsorship, Press, Support: *Have a question or concern about a topic or particular episode?Hello@TheLongevityGamePodcast.com *Interested in being a guest on the show? BeAguest@TheLongevityGamePodcast.com *Interested in supporting/sponsoring the show?Sponsors@TheLongevityGamePodcast.com #longevity, #hormoneoptimization, #womenshealth, #testosterone therapy, #weightloss #medications, #peptides, #mitochondrialhealth, #longevity #science

    38 min
  7. 12/01/2025

    Ep. 11 | Epigenetics, Longevity & the Immortal Jellyfish: Can We Rewind Human Aging?

    In this episode of The Longevity Game, host Michael Ward delves into the fascinating world of aging and longevity, exploring the potential to slow, pause, or even reverse the aging process. He discusses the role of epigenetics in aging, the remarkable capabilities of the immortal jellyfish, and the groundbreaking Yamanaka factors that can reprogram cells. The conversation emphasizes practical lifestyle changes that can influence biological age and highlights the exciting future of aging research.Jellyfish Age Backwards by Nicklas BrendborgGet it here --- https://a.co/d/2v3zMBVTakeaways-Aging can potentially be slowed, paused, or reversed.-Epigenetics plays a crucial role in how our genes express themselves.-The immortal jellyfish can reset its biological age, offering insights into human aging.-Yamanaka factors can reprogram adult cells to a youthful state.-Lifestyle choices significantly impact biological aging.-Exercise, nutrition, and stress management can reverse biological age.-Understanding epigenetics may lead to extending health span.-Aging is not a fixed destiny; it can be influenced by our choices.-Modern science is uncovering new possibilities in longevity research.-The biology of aging is being rewritten, opening new avenues for health. Chapters00:00 Introduction to Longevity and Aging01:19 Understanding Epigenetics and Its Role in Aging08:38 The Immortal Jellyfish: A Model for Reversing Aging10:18 Yamanaka Factors: Reprogramming Cells for Youth13:42 Practical Steps to Influence Your Epigenetic Age18:39 The Future of Aging: A New Era of Possibilities#longevity, #aging, #epigenetics, #immortal jellyfish, Yamanaka factors, #healthspan, #biologicalage, #cellularreprogramming, #lifestylemodifications, #agingreversal

    23 min
  8. Ep. 10 | 2025 Longevity Updates: Quad Agonists, MOTS-C Human Data, & Senolytic Stacking

    11/25/2025

    Ep. 10 | 2025 Longevity Updates: Quad Agonists, MOTS-C Human Data, & Senolytic Stacking

    In this episode of the Longevity Game Podcast, host Michael Ward discusses cutting-edge research in longevity, focusing on new peptide therapies, weight loss medications, and the impact of testosterone replacement therapy on brain health. The conversation highlights the importance of exercise in combating aging, the potential of quad agonist drugs for weight loss, and the promising results of the mitochondrial peptide MOTC. Additionally, the episode touches on the neuroprotective effects of TRT, emphasizing the holistic approach to health and longevity. Takeaways -The combination of exercise and senolytics can improve aging effects. -Quad agonist medications show promise for significant weight loss. -MOTC peptide enhances mitochondrial function and metabolic health. -TRT may play a crucial role in brain health as we age. -Prioritizing protein intake is essential for muscle retention on GLP-1s. -Exercise is vital for maintaining muscle mass and metabolic rate. -New data supports the efficacy of MOTC in improving insulin sensitivity. -The future of weight loss drugs is moving towards less muscle loss. -Senolytics may be integrated into regular training programs for better health. -Gratitude for health professionals working during holidays is important. Chapters 00:00 Introduction to Longevity and Performance Medicine 09:26 Exploring Senolytics and Exercise 18:35 Quad Agonist Weight Loss Breakthroughs 23:56 MOTC Peptide and Its Impact on Aging 26:00 Testosterone Replacement Therapy and Brain Health For Contact, Sponsorship, Press, Support: *Have a question or concern about a topic or particular episode?Hello@TheLongevityGamePodcast.com *Interested in being a guest on the show? BeAguest@TheLongevityGamePodcast.com *Interested in supporting/sponsoring the show?Sponsors@TheLongevityGamePodcast.com #longevity, #health, #peptides, #weightloss, #mitochondrialhealth, #TRT, #aging, #exercise, #metabolichealth, #GLP1

    32 min

About

Ready to outsmart Father Time with science, sweat, and a few laughs? Join Michael, a medical pro who trades lab coats for lively conversations, as he dives into the hottest trends in men’s health and beyond. You’ll get up-to-date insights on hormone optimization, muscle building, nutrition, longevity science, and the real stories behind the headlines. Whether you’re hitting midlife with gusto or just looking to maximize your health IQ, this show serves men and women who want to stay in peak form – body and brain.