Overheard In The Emergency Room

Dr Adrian Cois MD
  • 5.0 (1)
  • Medicine
  • Updated Daily

An emergency physician steps out of the resuscitation bay to talk about what really keeps you out of it. Each episode breaks down food, movement, sleep, stress, and the systems around us into clear, practical steps for living a longer and better life. No shame, no biohacking gimmicks - just evidence, stories from the ER, and habits you can actually stick with.

  1. 2d ago ·  Bonus

    Overhead Journal Club - SALT-ED Trial

    Welcome to Overheard Journal Club. In this new short-form series, ED physician Dr Adrian Cois takes a single paper that's changed how he practises and breaks it down conversationally — PICO, results, critical appraisal, and the practical "so what do I do with this on my next shift" synthesis. First up: SALT-ED. Self and colleagues, NEJM 2018. A pragmatic crossover trial in 13,347 noncritically ill adults asking whether balanced crystalloids beat normal saline as the default IV fluid in the emergency department. The answer reshaped Adrian's reflex — and gave him his favourite pharmacology joke. In this episode: why "normal" saline carries a supraphysiologic chloride load, how the pragmatic crossover design hit 88% adherence without blinding, what the MAKE30 composite outcome actually means, and the short list of hard indications for which saline still earns its place on the IV pole. Key takeaways •  In noncritically ill adults receiving IV fluids in theED, balanced crystalloids reduce major adverse kidney events at 30 dayscompared with saline (NNT 111). •  The mechanism is the supraphysiologic chloride load insaline, which causes hyperchloremic metabolic acidosis. •  Default to lactated Ringer's. Reserve saline for hyperkalemia, traumatic brain injury, hyponatremia, and drug compatibility issues — and even then, keep volumes modest. Disclaimer Educational content only. Not medical advice. Does not establish a physician-patient relationship. Always discuss management decisions with a qualified clinician.

    12 min

  2. May 29 ·  Bonus

    Quick Hit: The VO2 Max Myth Social Media Won’t Tell You About

    Two vehicles. Same destination. One question: which one will you actually do? If you’ve spent any time on health and fitness social media in the last two years, you’d be forgiven for thinking the only acceptable way to train your VO2 max is to strap on a weighted vest and grind out an hour of Zone 2 cardio every day. That’s what the algorithm is selling. The data tells a very different — and far more forgiving — story. In this Quick Hit, Dr Cois walks through the two evidence backed vehicles for building cardiorespiratory fitness in the average adult: Zone 2 cardio and interval training. Both work. Each has a place. And the choice between them is far more practical than philosophical. You’ll get the conversation test for finding your Zone 2 without a heart rate monitor, a 4-week interval progression that reliably moves the VO2 max needle by 5–10 points, the under prescribed half of the exercise guideline almost nobody is doing, and the simplest predictor of whether you’ll still be exercising a year from now. Plus: a heads-up on what’s coming next — Overheard Journal Club. Key Takeaways •  VO2 max is one of the strongest predictors of long-term health we have • Roughly half of US adults don’t meet even the aerobic activity guideline • Zone 2 is a way, not the way — and it has one underrated strength • Intervals are extraordinarily time-efficient and free up space for strength training • Adherence beats optimisation — the vehicle you’ll actually do is the one that wins Disclaimer Educational content only. Not medical advice. If you are starting a new exercise program, have known cardiovascular disease, or have symptoms with exertion, consult a qualified clinician before beginning.

    10 min

  3. May 22

    Your 16-Week Roadmap to Longevity: An ED Physician's 5-Pillar Playbook

    Welcome to the Season 1 finale of Overheard in the Emergency Room.   There's no single ED case anchoring this episode. There are fourteen of them — every patien every story, every lesson we walked through across the season. And rather than introduce one more case and pretend it summarises a whole year of conversations, Dr Cois pulls everything into a single playbook. Five Tier 1 pillars - in the order that actually matters: 1. A primary care physician who knows you and screens you (the single most evidence-backed longevity intervention in the literature). 2. A whole-plant-predominant diet, with specific steps to build fibre and plant diversity. 3. Exercise across three buckets — resistance training, cardiorespiratory fitness, and incidental movement. 4. Sleep, treated like your Olympic sport, with four concrete steps. 5. Stress management as a clinical skill, practised when calm. Plus a free 16-week Recapture Your Health roadmap PDF at DrCois.com — no email gate, no upsell. If you've been with us since Episode 1, thank you. If you're new, this is a great place to start. 🩺 Educational content only. Not medical advice. Cronometer is referenced without anyfinancial relationship. Let's chase less bad days and more good decades together. • A primary care physician isthe single most evidence-backed longevity intervention — more powerful than anysupplement, peptide, or wearable. • Diet, exercise, sleep, and stress management are the four lifestyle pillars that compound across decades - work all four, not one. • Aim for 30–40 g of fiber daily, 30+ unique plant species weekly, and 80% of your plate as whole plant foods. • Exercise has three required buckets: resistance training, cardiorespiratory fitness (Zone 2 + intervals), and incidental movement. • Treat sleep like an Olympicsport. Anchor with wake time, not bedtime. • Stress management is a learnable clinical skill — practise it in calm moments so it is available in real ones. •  Pick one pillar this fortnight. Behaviour change fails when people try to overhaul everything at once. Educational content only. This podcast does not provide medical advice and does not establish a physician–patient relationship. If you have symptoms concerning for a medical condition, please seek care from a qualified clinician.

    36 min

  4. May 15 ·  Bonus

    The Sleep Mistake Every Night-Shift Worker Is Making (ER Doc Explains)

    If you work night shifts, swing shifts, or any schedule that doesn't line up with the sun, this Quick Hit is your sleep playbook. Dr Cois — emergency physician and host of Overheard in the Emergency Room — walks through the evidence-based system he uses for himself and shares with his patients. You'll learn why shift work nudges your long-term risk of diabetes, cardiovascular disease, and other chronic conditions, and exactly what to do about it. The framework: four circadian behaviours (consistent wake time, daily nervous-system regulation, meal timing, pre-shift exercise) plus three environmental levers (cool room, true darkness, noise control). Honourable mentions cover sunglasses on the drive home, alcohol, strategic napping, screen light, sleep apnea screening, and how to use wearables without letting them stress you out. For the deep dive on sleep physiology, the hormone story, and the cohort evidence, listen to Episode 4 of the main season. Key Takeaways •  Shift work raises long-term cardiometabolic and chronic disease risk — but the levers to push back are well-defined. •  Cluster your shifts into blocks rather than scattering one-off nights. •  Stop eating four hours before sleep; cut caffeine in the second half of your shift. •  Exercise hard before your shift to manufacture the morning cortisol spike your body would normally produce on a day schedule. •  Build a daily nervous-system regulation practice — the car meditation is the easiest start. •  Protect your sleep environment: cool, dark, quiet, and household-aligned. Chapter Markers Chapter timestamps are maintained on YouTube as the master version — refer to the YouTube description for a full chapter breakdown. Disclaimer Educational purposes only. This podcast does not provide medical advice and does not establish a physician-patient relationship.

    11 min

  5. May 8 ·  Bonus

    Quick Hit: What Really Happens When You Go to the ER with Stomach Pain (ER Doctor Explains)

    “Dr Cois, I’ve got abdominal pain. What will happen to me when I come to the ED?”  It’s one of the most common questions in my inbox — and one of the top 3 reasons people present to my Emergency Department. In this Quick Hit, I walk you through what actually happens when you come in with stomach pain: the conversation we have, the 4 diagnoses we cannot miss, and the bigger story most patients never hear. Inside this episode: •  How emergency physicians use the SOCRATES framework to find the diagnosis before any test is ordered •  The 4 can’t-miss diagnoses — cholecystitis, appendicitis, diverticulitis, and small bowel obstruction — and how each one classically presents •  Non-GI causes of abdominal pain we always consider,including kidney stones, UTIs, aortic emergencies, and mesenteric ischaemia •  Why most recurrent abdominal pain comes back toconstipation, reflux, and non-alcoholic fatty liver disease •  A practical, week-by-week plan to safely increase yourfiber from 15 g to 40 g a day •  Why a CT scan isn’t always the right answer, and how to think about radiation risk in the ER •  The bold takeaway: if we don’t find a life threat, your next step isn’t another scan — it’s your Tier 1 habits Key Takeaways •  Most abdominal pain in the ER goes home safely •  80% of your plate should be plant foods •  Increase fiber gradually — not 15 g to 40 g overnight •  PPIs are a 2–6 week tool, not a forever medication •  Establish care with a primary care provider for any recurrent abdominal symptoms Chapter Markers Chapter timestamps available on the YouTube version of this episode — use that as the master reference. Disclaimer This episode is for educational purposes only and does not constitute medical advice. If you have symptoms that concern you, please contact your physician or local emergency services. Closing Send your next Quick Hit question via the contact form at DrCois.com or DM @dr_cois on socials. Fewer bad days. More good decades.

    10 min

  6. May 1 ·  Bonus

    Quick Hit: What Actually Happens When You Walk into the ER with Chest Pain

    Welcome to the very first Quick Hit — a brand new bonus series from Overheard in the Emergency Room where Dr Cois tackles the questions you’ve been sending in. Short. Focused. Practical. Today: “What actually happens when I walk into the Emergency Department with chest pain?” Dr Cois walks you through the full chest pain workup — why we move so fast, what door-to balloon time means, the three body systems behind every differential (heart, lungs, GI), which tests get ordered and when, and the diagnoses your ED doctor is quietly thinking about even when they don’t mention them. Plus the most important takeaway: when to come in, and what to do after. This is a clinical overview, not a deep evidence dive — but if you’ve ever sat in an ED waiting room wondering what was actually happening, this is the inside view. For the companion blog post and free resources, visit DrCois.com.  Key takeaways: ●     Chest pain gets immediate attention becausecardiovascular disease is the #1 killer in high-income countries ●     Door-to-balloon time is the metric that drives EDurgency around chest pain ●     Three main body systems frame every workup: heart,lungs, GI tract ●     ECG, troponin, chest X-ray, and bedside echo are theworkhorses; CT angiogram is risk-stratified ●     “Musculoskeletal” and “gastritis” are essentiallydiagnoses of exclusion — follow up with your PCP ●     If chest pain is new, severe, or doesn’t fit a patternyou recognise: come in Educational content only. Not medical advice. If you are experiencing chest pain, seek emergency care immediately.

    10 min

  7. Apr 24

    The Ultimate Supplement Guide: What the Evidence Actually Says (Creatine, BPC-157, NMN & More)

    The global wellness industry is a 6.8-trillion-dollar business — more than four times the size of global pharma — and it runs on supplements. But how much of it actually has evidence behind it? In Episode 14 of Overheard in the Emergency Room, Dr Adrian Cois — a board-certified Emergency Physician — walks through the published systematic reviews and meta-analyses for the nine most common supplements of 2026. Which ones have genuine evidence? Which ones are selling you a story? And how should you make decisions in a regulatory environment where, under DSHEA, supplements do not have to be proven safe or effective before they hit the shelf? The episode is anchored by two clinical stories: a coworker asking whether any supplement will stop her from getting sick, and an older man on Social Security spending his limited income on a herbal product while eating free meals at a senior centre. In between, Dr Cois breaks down creatine, vitamin D, omega-3, magnesium, and multivitamins — the five with reasonable evidence — and then takes apart NMN, berberine, collagen, and "detox" supplements — four with very thin evidence and very large marketing budgets. The episode also takes on the February 2026 FDA peptide reclassification, explains why BPC-157's evidence base is 35 rat studies and one uncontrolled case series, and closes with a blinded randomised-trial comparison between the Pfizer-BioNTech mRNA COVID vaccine trial and the retatrutide phase 2 obesity trial — revealing why influencers who dismissed the first while promoting the second are holding incoherent evidentiary standards. •  Supplements are Tier 2 by definition. They cannotsubstitute for diet, movement, sleep, stress management, and a primary carephysician. •  Five supplements with reasonable evidence in specificpopulations: creatine (resistance training), vitamin D (deficiency, older adults, prediabetes, pregnancy), omega-3 (specific cardiovascular contexts), magnesium (blood pressure, migraines), multivitamins (older adults with imperfect diets). •  Four with large marketing and small evidence: NMN, berberine (outside metabolic syndrome), collagen, and "detox" protocols. •  The BPC-157 evidence base is 35 preclinical animal studies and one uncontrolled case series in 12 humans. Reclassification by the FDA in 2026 restored access; it did not validate evidence. •  The three-question cabinet audit: Is there a medical reason? Can I name the evidence? What could this money do elsewhere? Note: Final timestamps to be filled in after recording. Use the YouTube chapter block above as the master, then synchronise to Spotify. Companion blog post with full references, evidence tables, and clinician-facing notes at drcois.com. Educational content only. Not medical advice. Always consult your own physician before starting, stopping, or modifying any supplement or medication regimen.

    45 min

  8. Apr 17

    The War on Protein

    A 35-year-old patient walked into my Emergency Department with diverticulitis — and told me he was eating 2.2 grams of protein per kilogram of body weight per day because he heard it on a podcast. He had rearranged his entire diet around a number that was never meant for him, and in doing so, had displaced the exact foods that would have protected him from the diagnosis he was sitting in front of me with. This episode is the conversation that case deserved. We walk through where the 0.8 g/kg RDA actually came from, why it's a floor rather than a target, and what the real evidence says about protein intake across three distinct populations — healthy adults, athletes, and adults over 65. We cover the landmark Harvard cohort data on plant versus animal protein, the controlled trial showing habitual vegans and omnivores build identical muscle when protein is matched, and the 2025 meta analysis that delivers the single most important finding for your grandparents: protein without resistance training does nothing. Along the way, we break down three myths — the "war on protein," the "plant protein is inferior" claim, and the "more is always better" fallacy — and flag the manipulation tactics behind each one. By the end of this episode, you'll know exactly how much protein you need based on your goals, where it should come from, and why none of it matters without the weights. •      Healthy adults maintaining muscle: 1.0–1.2 g/kg/day •      Adults resistance training: 1.2–1.6 g/kg/day •      Adults over 65: 1.0–1.5 g/kg/day, always with resistance training •      Prioritise plant sources; animal protein as a complement, not the foundation •      Protein without resistance training does not prevent sarcopenia For the full reference list, companion blog post, and free resistance training programme templates, visit DrCois.com. If this episode was useful, please share it with someone who's rearranged their diet around a protein number they never needed. Next episode: supplements — what works, what doesn't, and how to tell the difference.

    40 min
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An emergency physician steps out of the resuscitation bay to talk about what really keeps you out of it. Each episode breaks down food, movement, sleep, stress, and the systems around us into clear, practical steps for living a longer and better life. No shame, no biohacking gimmicks - just evidence, stories from the ER, and habits you can actually stick with.

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