Base by Base - Music

Gustavo Barcelos Barra
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Base by Base Music is the musical extension of Base by Base — a space for the original soundscapes, themes, and atmospheres that accompany science, reflection, and discovery. Here, music takes the lead: cinematic, thoughtful, and immersive compositions created to inspire focus, wonder, and intellectual curiosity.

  1. 19h ago

    Five Hundred Names

    This release contains only the music track from Base by Base Episode 459. Song title: Five Hundred Names Original Base by Base episode: 459: Cerebral palsy genetics: 515 candidate genes, evidence for 89 Article metadata: Article title: A phenotypic paradigm for cerebral palsy genetics Journal: The American Journal of Human Genetics DOI: 10.1016/j.ajhg.2026.08.007 Reference: Arterbery, A.S., Gargano, M.A., et al., and Robinson, P.N. (2026). A phenotypic paradigm for cerebral palsy genetics. The American Journal of Human Genetics 113, 1972-1986. https://doi.org/10.1016/j.ajhg.2026.08.007 Lyrics: Verse 1 Five hundred names on the page. Each one found in someone's child. Each one written down as the reason. Mantra Found is not the same as known. Found is not the same as known. Verse 2 Count everyone who carries it. Count how many of them have the palsy. Hold that against how often it comes anyway, two or three in every thousand births. Mantra Weigh it. Weigh it slow. Verse 3 Eighty-nine names grew heavier when the numbers were laid down beside them, and the rest did not grow lighter, they only stayed unproven, still waiting on the scale for more children, more pages, more time. Bridge Four hundred sixty children. Sixty genes. Sixteen with the weight behind them. Mantra Found is not the same as known. But known begins with found. Outro Five hundred names. Eighty-nine that hold. The rest are only waiting. Weigh it slow. Weigh it slow.

  2. 4d ago

    Half Means Home

    This release contains only the music track from Base by Base Episode 458. Song title: Half Means Home Original Base by Base episode: 458: Somatic or inherited? Reading TP53 risk from shared DNA Article metadata: Article title: Shared inheritance reveals landscape of somatic and germline cancer risk in TP53 Journal: The American Journal of Human Genetics DOI: 10.1016/j.ajhg.2026.07.011 Reference: MacGregor, H.A.J., Blundell, J.R., and Easton, D.F. (2026). Shared inheritance reveals landscape of somatic and germline cancer risk in TP53. The American Journal of Human Genetics 113, 1916-1928. https://doi.org/10.1016/j.ajhg.2026.07.011 Lyrics: Verse 1 Blood draw, letter back. Same word my family feared. Four hundred sixty-nine thousand read and the line I thought I had disappeared. Pre-Chorus Don't read the name. Read how much of me it is. Half of every cell is one thing. A rising sliver is another business. Chorus HALF MEANS HOME — it came down the line. LESS MEANS MINE — I grew it on my own time. HALF MEANS HOME. LESS MEANS MINE. Same letters on the page, different sign. Verse 2 Fifty-five of them turned up. Only six were passed down. The rest climbed with the birthdays — two point three a decade, going up, never down. Pre-Chorus The six that ran in blood of kin sat soft, sat partial, sat halfway in. The loud ones, the famous ones, nobody handed me those. I made them. Chorus HALF MEANS HOME — it came down the line. LESS MEANS MINE — I grew it on my own time. HALF MEANS HOME. LESS MEANS MINE. Same letters on the page, different sign. Bridge Not the bone. Not the breast. It's the marrow keeping score. Sixteen times the blood. That old name don't live here anymore. Shared the segment, shared the street — that's how we told them apart. Not the spelling. The inheritance. Not the letter. The start. Outro Half means home. Less means mine. Count the fraction. Read the line. Half means home. Less means mine.

  3. 5d ago

    One Less, One More

    This release contains only the music track from Base by Base Episode 457. Song title: One Less, One More Original Base by Base episode: 457: A deletion that raises Alzheimer risk, a duplication that lowers it Article metadata: Article title: Exome analysis of 22,319 individuals links extremely rare copy-number variants and 22q11.21 dosage to Alzheimer risk Journal: The American Journal of Human Genetics DOI: 10.1016/j.ajhg.2026.07.013 Reference: Quenez O, Schramm C, Cassinari K, Nicolas A, Groeneveld J, Huguet G, et al. Exome analysis of 22,319 individuals links extremely rare copy-number variants and 22q11.21 dosage to Alzheimer risk. The American Journal of Human Genetics. 2026;113(10):1-19. doi:10.1016/j.ajhg.2026.07.013 Lyrics: Verse 1 Twenty-two thousand read. Every letter, every gap. One little stretch of twenty-two kept showing on the map. Pre-Chorus One side heading down. One side climbing up. Same short street, same short block — different measure in the cup. Chorus ONE LESS — and the risk goes UP. ONE MORE — and it settles DOWN. Same little piece of the same little place turning it around. ONE LESS — only in the early years. ONE MORE — easy in the crowd. Same little piece, read it twice: count it, count it out loud. Verse 2 Not one deletion showed in nine thousand walking free. But the doubles kept on turning up right where you want to be. Chorus ONE LESS — and the risk goes UP. ONE MORE — and it settles DOWN. Same little piece of the same little place turning it around. Bridge Put the gene back in the cell — it clears the plaque right up. That's the piece we can see so far. Rare is rare enough. It ain't a shield. It's a lean. It tilts you. It don't save. Some who carried two of them still came the harder way. Final Chorus ONE LESS — and the risk goes UP. ONE MORE — and it settles DOWN. Not a promise, just a tilt, but you take it when it's found. ONE LESS. ONE MORE. Same little piece, both ways. Count it once, then count again — that's the whole thing, right there.

  4. 6d ago

    Where the Light Is

    This release contains only the music track from Base by Base Episode 456. Song title: Where the Light Is Original Base by Base episode: 456: Beyond exons: where heritability hides as traits get more polygenic Article metadata: Article title: Beyond exons: Linking noncoding heritability and polygenicity across complex human traits and disorders Journal: The American Journal of Human Genetics DOI: 10.1016/j.ajhg.2026.08.012 Reference: Fuhrer J, Shadrin AA, Hughes T, Parker N, Hindley G, Frei E, Nguyen D, Smeland OB, Djurovic S, Andreassen OA, Dale AM, Frei O. Beyond exons: Linking noncoding heritability and polygenicity across complex human traits and disorders. The American Journal of Human Genetics. 2026;113(10):1-13. doi:10.1016/j.ajhg.2026.08.012 Lyrics: Verse 1 We searched the lit part of the street, the small bright names we knew. Two in a hundred, read out clean, and still it wouldn't come through. The rest lay dark and open wide, too far to walk across, so we filed it all as background and we counted it as loss. Pre-Chorus But it wasn't ever missing. It was thin, and it was wide. Chorus It was never where the light is. It was scattered through the dark. Not a single voice worth naming, just a million, faint and stark. And the more it takes to make you, the further out it goes, past the letters that we counted, into everything that flows. Verse 2 For the body it stays closer: what you weigh and how you grow, near a fifth still in the letters, in the part we thought we know. But for the mind it wanders out, for the worry and the word, down to one in eight, and drifting into all we never heard. Bridge And the middle never moved at all. It held its steady share. Half of everything you are was always waiting there. Not the bright part, not the far part, just the quiet in between, the same in all of us, unchanged, the half we've never seen. Final Chorus It was never where the light is. It was scattered through the dark. Not a single voice worth naming, just a million, faint and stark. So we're learning where to look now. It was never in one place. It was all of it, together, spread across the empty space.

  5. Sep 7

    All Normal

    This release contains only the music track from Base by Base Episode 455. Song title: All Normal Original Base by Base episode: 455: Agentic genomics: the bottleneck moves from code to judgment Article metadata: Article title: Agentic genomics: From pipeline automation to autonomous validation Journal: Cell Genomics DOI: 10.1016/j.xgen.2026.101305 Reference: Corpas M, Guio H, Fatumo S. Agentic genomics: From pipeline automation to autonomous validation. Cell Genomics. 2026;6(8):101305. doi:10.1016/j.xgen.2026.101305 Lyrics: Verse 1 I gave it one sentence, no more than a line. It picked all the tools and it never asked mine. It hit a bad index, then patched its own break, and handed me answers no human could make. Pre-Chorus So hand it a file with no data at all, malformed and empty, no reads to recall. If nothing goes wrong and it never once stalls, then no one is checking. No one at all. Chorus IT SAID ALL NORMAL. Fifty-one doses, and nothing was there. IT SAID ALL NORMAL — a confident answer from empty air. Who checks the machine when the machine runs clean? Who reads what it wrote when nobody's there? Verse 2 It never crashes. That's the cruelest part. It fails in a shape that looks clean from the start. Two genome builds mixed, and the numbers all slide — it passes each check with the meaning gone inside. Bridge The bottleneck moved, and it landed on us: we make it in minutes, we read it for weeks. It leans on whatever data it learned, then hands the same score to whoever it meets. Final Chorus IT SAID ALL NORMAL. Fifty-one doses, and nothing was there. IT SAID ALL NORMAL — a confident answer from empty air. Somebody found it. Somebody read. That's the whole job now — the part in your head.

  6. Sep 2

    Remédio de Outra Guerra

    This release contains only the music track from Base by Base Episode 454. Song title: Remédio de Outra Guerra Original Base by Base episode: 454: Efavirenz retarda a doença priônica mexendo no colesterol do cérebro [PT] Article metadata: Article title: Treatment with efavirenz extends survival in a Creutzfeldt-Jakob disease model by regulating brain cholesterol metabolism Journal: JCI Insight DOI: 10.1172/jci.insight.190296 Reference: Ali T, Cashion J, Hannaoui S, Ahmed-Hassan H, Schatzl H, Gilch S. Treatment with efavirenz extends survival in a Creutzfeldt-Jakob disease model by regulating brain cholesterol metabolism. JCI Insight. 2025;10(14):e190296. doi:10.1172/jci.insight.190296 Lyrics: Verso 1 Ele nasceu pra outra briga, numa guerra que já passou; ficou guardado na prateleira e o mundo nem reparou. Mas tem porta que se abre sem ninguém ter procurado: o remédio de outra guerra entrou por onde ninguém tinha olhado. Pré-refrão Não vem calar o que se diz, não encosta no recado; vem abrir o ralo velho que o cérebro tinha fechado. Refrão REMÉDIO DE OUTRA GUERRA chegou sem pedir licença! REMÉDIO DE OUTRA GUERRA quase nada já compensa — não é cura, é tempo a mais, e tempo aqui é o que faz diferença. Verso 2 Não é dose de gigante, é um tiquinho, quase nada: trezentas vezes menor que a receita de outra estrada. E mesmo chegando tarde, com a doença já plantada, ainda sobrou caminho pra segurar a jornada. Ponte No bicho que já trazia a proteína pra estudar, o que vinha muito rápido começou a demorar. E o que sai do colesterol encontra por onde passar: o cérebro se alivia do que não conseguia limpar. Refrão final REMÉDIO DE OUTRA GUERRA chegou sem pedir licença! REMÉDIO DE OUTRA GUERRA quase nada já compensa — outra estrada pro mesmo lugar, e é isso que faz diferença.

  7. Aug 31

    Turn the Tide in My Brain

    This release contains only the music track from Base by Base Episode 453. Song title: Turn the Tide in My Brain Original Base by Base episode: 453: Efavirenz slows sCJD progression by reshaping brain cholesterol Article metadata: Article title: Treatment with efavirenz extends survival in a Creutzfeldt-Jakob disease model by regulating brain cholesterol metabolism Journal: JCI Insight DOI: 10.1172/jci.insight.190296 Reference: Ali T, Cashion J, Hannaoui S, Ahmed-Hassan H, Schatzl H, Gilch S. Treatment with efavirenz extends survival in a Creutzfeldt-Jakob disease model by regulating brain cholesterol metabolism. JCI Insight. 2025;10(14):e190296. https://doi.org/10.1172/jci.insight.190296. Lyrics: Verse 1 In the quiet of a failing light, Something twisted, running wild inside. Pages blur, but I still can fight, If there’s a switch that turns the dark aside. Pre-Chorus Low dose, late start, still a spark in the storm, A hidden lever in the chemistry. If the wheels can spin where they used to deform, Then maybe time can bend for me. Chorus Turn the tide in my brain, let the current run clean, Break the loop where the shadows remain. If you move the cholesterol, you can change what’s unseen— Hold the line, buy the days, ease the strain. Verse 2 Bright screens, long nights, counting every sign, Watching markers fall like ash in air. Less of that resistant, jagged spine, As the buildup loosens its grip in there. Bridge Wake the enzyme up, let it open the gate, Send the excess out in a safer form. Cool the signal that keeps feeding the weight, Drain the droplets, quiet down the swarm. Final Chorus Turn the tide in my brain, let the current run clean, From the first hard miles to the late-stage rain. If you move the cholesterol, you can change what’s unseen— Hold the line, steal the hours, break the chain.

  8. Aug 28

    Quem Ainda Faz Ninho

    This release contains only the music track from Base by Base Episode 452. Song title: Quem Ainda Faz Ninho Original Base by Base episode: 452: Reduzir a PrP funciona em todas as linhagens [PT] Article metadata: Article title: Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints Journal: Nucleic Acids Research DOI: 10.1093/nar/gkaa616 Reference: Minikel EV, Zhao HT, Le J, O’Moore J, Pitstick R, Graffam S, Carlson GA, Kavanaugh MP, Kriz J, Kim JB, Ma J, Wille H, Aiken J, McKenzie D, Doh-ura K, Beck M, O’Keefe R, Stathopoulos J, Caron T, Schreiber SL, Carroll JB, Kordasiewicz HB, Cabin DE, Vallabh SM. Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints. Nucleic Acids Research. 2020;48(19):10615–10631. doi:10.1093/nar/gkaa616 Lyrics: Verso 1 Na bancada, madrugada, tem alguém pra anotar: não sabe quem tomou nada, não sabe quem vai melhorar. Só marca se fez o ninho, se arrumou o seu lugar, se no pau que fica girando ainda deu pra se aguentar. Pré-refrão A doença não vem gritando, não bate na porta, não chama: vai levando de mansinho o passo, o peso e a cama. Refrão QUEM AINDA FAZ O NINHO ainda tem o que contar! QUEM AINDA FAZ O NINHO não desistiu de ficar! Pouco já muda o caminho — anota aí: dá pra segurar! Verso 2 Cinco jeitos diferentes da mesma coisa chegar; foram todos, um por um, nenhum deles escapar. E o bicho não aprendeu o caminho de driblar: voltaram pra ver de novo e não teve como passar. Ponte Tem quem nasce com metade e vive sem reclamar; baixar não é ficar sem — é ter de sobra pra dar. Mesmo com o sinal aceso inda tem o que fazer: teve bicho que ganhou meses só de alguém não se render. Refrão final QUEM AINDA FAZ O NINHO ainda tem o que contar! QUEM AINDA FAZ O NINHO não desistiu de ficar! Em toda cepa, em todo estágio — anota aí: dá pra segurar!

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About

Base by Base Music is the musical extension of Base by Base — a space for the original soundscapes, themes, and atmospheres that accompany science, reflection, and discovery. Here, music takes the lead: cinematic, thoughtful, and immersive compositions created to inspire focus, wonder, and intellectual curiosity.

Information

  • Creator
    Gustavo Barcelos Barra
  • Years Active
    2026
  • Episodes
    100
  • Rating
    Clean
  • Copyright
    © 2026
  • Show Website
    Base by Base - Music