The Anatomy Purist

AnatomyM8

Anatomy without agenda. Pure, deep, surgical. The Anatomy Purist is for surgeons, students, and anyone who loves anatomy beyond the knife. Each episode takes one structure, one region, or one concept and dissects it properly: the embryology, the etymology, the clinical evolution, the surgical history. No revision cards. No question banks. No shortcuts. If you’re preparing for MRCS, visit anatomym8.com for the structured audio series, handbook, and question bank built to take everything here and make it examinable.

Episodes

  1. Sep 3

    Episode 5: Innvervation. Why does my LA keep failing?

    Episode 5 of The Anatomy Purist. Dev opens with a block that failed in an abscess and works back through the innervation of the skin: the four cutaneous mechanoreceptors, including the one that is not encapsulated; the real two-point discrimination bands and Lundborg and Rosén’s case against trusting them; why innocuous cold travels on A-delta and not C fibres; the dermatome map problem almost nobody teaches; why local anaesthetic really fails in infected tissue, which is not simply pH; Seddon versus Sunderland; and what nerve coaptation in a sensate flap actually buys you. AnatomyM8.com Every reference verified, every unverifiable claim flagged as unverifiable. REFERENCES Standring S, editor. Gray’s Anatomy: The Anatomical Basis of Clinical Practice. 42nd Ed. London: Elsevier; 2020.Johnson KO. The roles and functions of cutaneous mechanoreceptors. Curr Opin Neurobiol. 2001; 11(4):455-61. PMID: 11502392. doi:10.1016/s0959-4388(00)00234-8.Johansson RS, Flanagan JR. Coding and use of tactile signals from the fingertips in object manipulation tasks. Nat Rev Neurosci. 2009;10(5):345-59. PMID: 19352402. doi:10.1038/nrn2621.Purves D, Augustine GJ, Fitzpatrick D, et al., editors. Neuroscience. 2nd ed. Sunderland (MA): Sinauer Associates; 2001. Chapter: Mechanoreceptors Specialized to Receive Tactile Information. NCBI Bookshelf ID: NBK10895.Treede RD, Meyer RA, Campbell JN. Evidence for two different heat transduction mechanisms in nociceptive primary afferents innervating monkey skin. J Physiol. 1995;483(Pt 3):747-58. PMID: 7776255.Yarnitsky D, Ochoa JL. Release of cold-induced burning pain by block of cold-specific afferent input. Brain. 1990;113(Pt 4):893-902. PMID: 2397391. doi:10.1093/brain/113.4.893.McKemy DD. The molecular and cellular basis of cold sensation. ACS Chem Neurosci. 2013;4(2):238-47. PMID:3421674.Lee MWL, McPhee RW, Stringer MD. An evidence-based approach to human dermatomes. Clin Anat. 008; 21(5):363-73. PMID: 18470936. doi:10.1002/ca.20636.Seddon HJ. Three types of nerve injury. Brain. 1943; 66(4):237-88. doi:10.1093/brain/66.4.237.Sunderland S. A classification of peripheral nerve injuries producing loss of function. Brain. 1951; 74(4):491-516. PMID: 14895767. doi:10.1093/brain/74.4.491.Mackinnon SE, Dellon AL. Surgery of the Peripheral Nerve. New York: Thieme; 1988. Dellon AL. Evaluation of Sensibility and Re-education of Sensation in the Hand. Baltimore: Williams & Wilkins; 1981. Lundborg G, Rosén B. The two-point discrimination test — time for a re-appraisal? J Hand Surg Br. 2004; 29(5):418-22. PMID: 15336741. doi:10.1016/j.jhsb.2004.02.008. Punnia-Moorthy A. Buffering capacity of normal and inflamed tissues following the injection of local anaesthetic solutions. Br J Anaesth. 1988;61(2):154-9. PMID: 3415887. doi:10.1093/bja/61.2.154. Ueno T, Tsuchiya H, Mizogami M, Takakura K. Local anesthetic failure associated with inflammation: verification of the acidosis mechanism and the hypothetic participation of inflammatory peroxynitrite. J Inflamm Res. 2008;1:41-8. PMID: 22096346. doi:10.2147/jir.s3982.Kabakcı AG, Bozkır MG. Dimension, location and clinical importance of supraorbital foramen and notch: a combined cadaveric and dry skull study. Aesthetic Plast Surg. 2025;49(1):322-33. Epub 2024 Jul 1. PMID: 38951229. doi:10.1007/00266-024-04196-7.Santanelli F, Tenna S, Pace A, Scuderi N. Free flap reconstruction of the sole of the foot with or without sensory nerve coaptation. Plast Reconstr Surg. 2002;109(7):2314-22. PMID: 12045556. doi:10.1097/00006534-200206000-00023.Neurapraxia. In: StatPearls. Treasure Island (FL): StatPearls Publishing. NCBI Bookshelf ID: NBK560501.

About

Anatomy without agenda. Pure, deep, surgical. The Anatomy Purist is for surgeons, students, and anyone who loves anatomy beyond the knife. Each episode takes one structure, one region, or one concept and dissects it properly: the embryology, the etymology, the clinical evolution, the surgical history. No revision cards. No question banks. No shortcuts. If you’re preparing for MRCS, visit anatomym8.com for the structured audio series, handbook, and question bank built to take everything here and make it examinable.