Dr. John Campbell

Campbellteaching
  • 4.5 (2)
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Hello Everyone, My name is John Campbell and I am a retired Nurse Teacher and former clinical nurse based in England. I also do some teaching in Asia and Africa when time permits. These videos are to help students to learn the background to all forms of health care. My PhD focused on the development of open learning resources for nurses nationally and internationally. LinkedIn profile, https://www.linkedin.com/in/dr-john-campbell-5256223b/ Twitter, https://twitter.com/Johnincarlisle Disclaimer; These media including videos, book, e book, articles, podcasts are not peer-reviewed. They should never replace individual clinical judgement from your own health care provider. No media-based material on this channel is suitable for using as professional medical advice. All comments are also for educational purposed only and must never replace advice from your own health care provider

  1. 55m ago

    Rampant BA 5

    Rant warning. There is a significant rant in this video starting at 15 minutes 20 seconds. Viewer discretion is advised as some may find this objectionable.Uploaded 22-07-22CDC variant nowcasthttps://covid.cdc.gov/covid-data-tracker/#variant-proportionsBA.5 77.9%BA.4 12.8%BA.2.12.1 8.6%BA.2 0.6%BA.1 0%Delta 0%Others 0%https://www.nytimes.com/interactive/2021/us/covid-cases.html?campaign_id=185&emc=edit_yct_20220722&instance_id=67312&nl=coronavirus-tracker®i_id=110300449&segment_id=99240&te=1&user_id=0b87b8c1eea981ec0514047bbfa553caRisk of death in vaccinated and unvaccinatedHospital admission risk goes up with ageMr. Biden, (79) isolating at homeFully vaccinated, had second booster, end of MarchTested positive, Thursday. very mild symptomsTaking PaxlovidWhite House has stringent measures to prevent infectionhttps://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/articles/coronaviruscovid19/latestinsights5.77% in England (1 in 17 people)6.03% in Wales (1 in 17 people)4.82% in Northern Ireland (1 in 20 people) 6.48% in Scotland (1 in 15 people)Long covid, data to 27 May 2022 Coronavirus Infection Survey, 12 to 16 weeks laboratory-confirmed infectionBA.1 4.5% BA.2 4.2%Delta 5.0% of triple-vaccinated adults,Zoe datahttps://health-study.joinzoe.com/dataJapan, highest level of vigilance https://www.theguardian.com/world/2022/jul/22/japan-urges-highest-level-of-vigilance-as-omicron-subvariant-drives-record-covid-surgeNew wave of infectionsOmicron BA.5 subvariantCases, + 186,000, disproportionately affected children and young peopleRecent rise in cases, 60 +Lowest per capita rate of 38 OECD countries246 per million people Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices

  2. 1h ago

    No protection against death

    Open access using this link:Uploaded 13-12-23https://onlinelibrary.wiley.com/doi/10.1111/eci.14136Effectiveness of a fourth SARS-CoV-2 vaccine dose in previously infected individuals from AustriaEvidence is limited on the effectiveness of a fourth vaccine dose against coronavirus disease 2019,in populations with prior SARS-CoV-2 infections. We estimated the risk of COVID-19 deaths (primary outcome)We estimated the risk of SARS-CoV-2 infections (secondary outcome)MethodsAustria nationwide retrospective observational study. 1 November to 31 December 2022Primarily comparing individuals with four versus three vaccine doses. Whole population data.Results3,986,312 previously infected individuals281,291 (7,1%) had four vaccinations at baseline1,545,242 (38.8%) had three vaccinations at baseline We recorded69 COVID-19 deaths89,056 SARS-CoV-2 infectionsThe majority of COVID-19 deaths and a significant proportion of all-cause deaths occurred in nursing home residentsRelative vaccine effectiveness (rVE) for four versus three vaccine doses-24% against COVID-19 deaths17% against SARS-CoV-2 infections. Protection against infection rapidly diminished over time,and infection risk with four vaccinations was higher during extended follow-up until June 2023. Adjusted HR for all-cause mortality for four versus three vaccinations was 0.79.That is people with a 4th dose were only 79% as likely to die(Suggesting healthy vaccinee bias, i.e. healthier persons received more vaccine doses)DiscussionIn previously infected individuals, a fourth vaccination did not reduce COVID-19 death risk, but with transiently reduced risk of SARS-CoV-2 infections,and reversal of this effect in longer follow-up. All-cause mortality data suggest healthy vaccinee bias.More detailsMostly Pfizer vaccine, some ModernaIn this study, overall case fatality rate, 0.08%.(IFR, ? 0.008% if 10% of infections picked up)Individuals with repeated previous infections had reduced re-infection riskNatural immunity may be a main determinant of immunological protection in a populationBy end 2022, the vast majority of the global population had already acquired some immune protectionCompared to three vaccine doses, those with fewer or no vaccinations did not differ with regard to COVID-19 mortality,but had reduced risk of SARS-CoV-2 infections.In 2022, infection fatality rates due to SARS-CoV-2 significantly declined suggesting transitioning into endemicity.In general, our study results question whether recommendations for repeated vaccine boosters against SARS-CoV-2 are currently justified for large parts of the general population with a history of previous infections. Measures against SARS-CoV-2 including vaccine policy should be critically re-assessed for their risk-to-benefit ratio.As most SARS-CoV-2 infections are asymptomatic or mild in an endemic phase, effectiveness of vaccinations should be primarily evaluated according to hard clinical outcomes (e.g. COVID-19 deaths)Extended follow-upFrom 1 January to 30 June 2023Omicron XBB.1.5. was the predominant variant225 COVID-19 deaths174,174 SARS-CoV-2 infections. Analyses in 2023 confirm no relative vaccine effectiveness (rVE) for four versus three vaccine doses for COVID-19 mortality,but show higher risk of SARS-CoV-2 infections with a rVE of −17%Free download John’s textbooks in high res pdf.https://drjohncampbell.co.ukCheck out Campbell's Physiology Notes Dr John Campbell Sold by author on eBay!https://www.ebay.co.uk/itm/155780745424?mkcid=16&mkevt=1&mkrid=711-127632-2357-0&ssspo=K6raxMZrQnm&sssrc=4429486&ssuid=K6raxMZrQnm&var=&widget_ver=artemis&media=EMAIL Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices

  3. 2h ago

    % lethal rate SARS virus

    Virus being experimented on in China. https://www.researchgate.net/publication/377199018_Lethal_Infection_of_Human_ACE2-Transgenic_Mice_Caused_by_SARS-CoV-2-related_Pangolin_Coronavirus_GX_P2Vshort_3UTR https://www.biorxiv.org/content/10.1101/2024.01.03.574008v1.full.pdf https://www.theepochtimes.com/health/chinese-scientists-reveal-experiments-with-virus-100-percent-fatal-to-mice-5560854?utm_source=atcn&utm_content=hw1016multicomp&utm_medium=email&utm_campaign=atc&utm_term=hws1comp SARS-CoV-2-related pangolin coronavirus GX_P2V, can cause 100% mortality in human ACE2-transgenic mice, potentially attributable to late-stage brain infection. Paper Authors Beijing Advanced Innovation Center Beijing University of Chemical Technology, The Fifth Medical Center of PLA General Hospital, Beijing, China. Medical School, Nanjing University, China (including a doctor trained by the Chinese military, Yigang Tong) Purpose of study Assessed virus pathogenicity Risk 100% IFR underscores a spillover risk of GX_P2V into humans, and provides a unique model for understanding the pathogenic mechanisms of SARS-CoV-2-related viruses. Details GX_P2V isolate was actually a cell culture-adapted mutant In this study, we cloned this mutant This is not a wild type virus It is possible that GX_P2V C7 has undergone a virulence-enhancing mutation. GX_P2V is capable of rapid mutation rates. High viral loads detected in both lung and brain tissues. Surprisingly, all the mice that were infected with the live virus succumbed to the infection within 7-8 days post-inoculation, Resulted in 100% mortality in the hACE2 mice. Clinical features Weight loss, Piloerection, hunched posture, sluggish movements, and their eyes turned white. Significant amounts of viral RNA in the brain, lung, turbinate, eye, trachea, reducing with time Infection did not lead to significant inflammatory reactions or cytokine storm Brain with high viral counts increasing during infection ACE2 receptors are found in the human brain Brainstem (especially areas regulating breathing and cardiovascular control) Hypothalamus Substantia nigra Cortex (low levels) Endothelial cells lining cerebral blood vessels Some neurons and glial cells The choroid plexus Justin Kinney, associate professor, Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory, U.S. “I am especially concerned that the paper does not say what biosafety level the work was performed at. Coronavirus research in China is often done at a biosafety level (BSL-2) that is inadequate for working with potential pandemic pathogens that might be transmitted by air. “Indeed, coronavirus research done at BSL-2 may have caused the COVID-19 pandemic. And by showing that the coronavirus has a surprisingly high pathogenicity, the work underscores the need for extreme caution when working with novel coronaviruses.” Justin Goodman, senior vice president of the White Coat Waste Project, a U.S. nonprofit China-based scientists have been conducting “dangerous and deadly tests on mice.” “This is why shipping U.S. tax dollars to foreign adversaries’ unaccountable animal labs is a recipe for disaster …… Learn more about your ad choices. Visit megaphone.fm/adchoices

    % lethal rate SARS virus

  4. 3h ago

    Vitamin D and Global Shift

    Download a free copy of VITAMIN D3 and the Great Biology Reset, by Professor David Anderson and Dr David Grimes. https://dgreatbiologyreset.com/#download Dr Grime’s book to introduce the importance of vitamin D https://yorkbookshop.com/health-and-personal-development/307-vitamin-d-deficiency-and-covid-19-its-central-role-in-a-world-pandemic.html Welcome to Professor David Coussmaker Anderson, who has had a lifetime in medicine, consultant physician, professor of endocrinology, medical researcher, medical author, medical teacher and lecturer. Member of the royal society of medicine, member of the American endocrine society … we could go on. Learn more about your ad choices. Visit megaphone.fm/adchoices

    Vitamin D and Global Shift

  5. 4h ago

    mRNA horizon

    Moderna Receives U.S. FDA Approval for RSV Vaccine mRESVIA(R) https://news.modernatx.com/news/news-details/2024/Moderna-Receives-U.S.-FDA-Approval-for-RSV-Vaccine-mRESVIAR/default.aspx May 31, 2024 Moderna, today announced that the U.S. Food and Drug Administration (FDA) has approved mRESVIA (mRNA-1345), an mRNA respiratory syncytial virus (RSV) vaccine, to protect adults aged 60 years and older from lower respiratory tract disease caused by RSV infection. The approval was granted under a breakthrough therapy designation and marks the second approved mRNA product from Moderna. Stéphane Bancel, Chief Executive Officer of Moderna. The FDA approval of our second product, mRESVIA, builds on the strength and versatility of our mRNA platform Moderna expects to have mRESVIA available for eligible populations in the U.S. by the 2024/2025 respiratory virus season. Moderna has filed for mRNA-1345 approval with regulators in multiple markets around the world. https://www.clinicaltrialsarena.com/news/moderna-races-ahead-in-flu-and-covid-19-combo-vaccine-race-with-phase-iii-win/ Moderna races ahead in flu and Covid-19 combo vaccine race with Phase III win Moderna injection mRNA-1083 Comprises a seasonal influenza vaccine candidate, mRNA-1010, and a next-generation Covid-19 vaccine prospect called mRNA-1283. Moderna announces positive data from a Phase III trial of its mRNA vaccine candidate. Now, in a Phase III trial (NCT06097273) for mRNA-1083 Moderna “statistically significantly higher immune responses” compared to existing vaccines on the market. The trial met its primary endpoints, Moderna said in a 10 June press release. Immune response was seen across three influenza virus strains (H1N1, H3N2, and B/Victoria) and against SARS-CoV-2. Although Moderna has not published the full dataset from the Phase III trial, it plans to present the results in more detail at an upcoming medical conference, in addition to a submission for publication. The company said it “will engage with regulators on next steps”. Other mRNA vaccines in development Moderna Advances Multiple Vaccine Programs to Late-Stage Clinical Trials https://news.modernatx.com/news/news-details/2024/Moderna-Advances-Multiple-Vaccine-Programs-to-Late-Stage-Clinical-Trials/default.aspx Cytomegalovirus (CMV) CMVictory is a pivotal Phase 3 trial evaluating mRNA-1647 against primary CMV infection in women 16 to 40 years of age. Epstein-Barr virus (EBV) mRNA-1189 The randomized, observer-blind, placebo-controlled study is fully enrolled. Herpes simplex virus (HSV) mRNA-1608 Phase 1/2 trial The randomized 1:1:1:1, observer-blind, controlled study is fully enrolled with 300 participants in the U.S. Varicella-Zoster virus (VZV) Moderna's VZV vaccine candidate mRNA-1468 has initial data available from a Phase 1/2 trial Norovirus The Company is advancing mRNA-1403 toward a pivotal Phase 3 trial. Learn more about your ad choices. Visit megaphone.fm/adchoices

    mRNA horizon

  6. 5h ago

    Virologist, full interview

    DNA contamination clearly identified by Dr David SpeicherUploaded 12-03-25An Injection of Truth. Healing Humanity.https://aninjectionoftruth.ca/The David Declarationhttps://thedaviddeclaration.org/Summary: Canadian Virologist Dr. David Speaker's Interview on Vaccine DNA Contamination(00:01-01:08) Dr. David Speaker presented unpublished data on DNA contamination in COVID vaccines that was rejected by four scientific journals without peer review.(01:08-03:22) Speaker's analysis shows COVID vaccine vials from Ireland, Canada, and Australia contain DNA contamination (including spike protein DNA and SV40 sequences) at levels exceeding legal maximums, with Australian samples showing particularly high levels.(03:22-05:23) The PCR studies used a low cycle threshold of 12 (compared to COVID diagnosis thresholds of 30+), showing SV40 DNA not only inhibits the p-53 tumor suppressor gene but enhances integration of DNA fragments into the human genome.(05:23-07:19) Current DNA contamination threshold levels were established for naked DNA, but modern vaccines use lipid nanoparticles that increase cellular uptake by 100x, suggesting safety thresholds should be 100x lower.(07:19-09:51) FDA/WHO guidelines for allowable DNA contamination became more lenient over time, increasing from 10 picograms per dose (pre-1996) to 10,000 picograms (10 nanograms) per dose after 1996.(09:51-12:26) The latest JN1 vaccine formulations still show high contamination levels despite manufacturers presumably being aware of the issue.(12:26-15:41) Speaker supports the David Declaration and Northern Group Letter of Concern, which call for a return to evidence-based medicine, a moratorium on mRNA technology, and support for vaccine-injured individuals.(34:04-39:05) The contamination data is presented on both linear and logarithmic scales, with the logarithmic scale demonstrating how dramatically the levels exceed historical (1986) safety limits. Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices

  7. 6h ago

    Duty to the next generation

    More valuable insights from doctor, endocrinologist, author, medical researcher and teacher, professor David Anderson. Link to order or download, Vitamin D and the Great Biology Reset, https://dgreatbiologyreset.com/ Uploaded 26-06-25Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices

  8. 7h ago

    Birth rates down after vaccine

    Rates of Successful Conceptions According to COVID-19 Vaccination Status: Data from the Czech RepublicUploaded 11-05-25https://www.preprints.org/manuscript/202504.2487/v1Birth rates about 30% lower in vaccinated v unvaccinated women1,300,000 womenTotal fertility rate in the Czech Republic2021, 1.83 births per 1000 women2022, 1.62 births per 1000 women2023, 1.45 births per 1000 womenDeclining birth rates have been reported in many countries following the COVID-19 pandemic,and have been linked with economic instability, social inequality, and related social restrictions Adverse effects of COVID-19 vaccination on human menstrual cycle characteristics have been observed, but limited data are available on the relationship between vaccination status and birth rates. We used nationwide data from the Czech RepublicTo examine rates of successful conceptionsi.e., conceptions leading to live births 9 months later, for women,either vaccinated or unvaccinated against COVID-19,before successful conceptions Data from January 2021 to December 2023Monthly COVID-19 vaccination and birth data for women aged 18-39 years in the Czech RepublicNumbers of SCs per month per 1,000 women, preconception-vaccinated or unvaccinated womenPfizer and Moderna mRNA vaccines comprised 96% of all vaccine doses,Results1,300,000 women aged 18-39 years in the Czech RepublicThe proportion of COVID-19-vaccinated women increased until reaching a steady state of around 70% by the end of 2021. During the entire study period, SCs per 1,000 women were considerably lower for women who were vaccinated, compared to those that were unvaccinated.At the end of June 202139% of all women had been vaccinated, those vaccinated before SC contributed only 7% of all SCs.Furthermore, SC rates for the vaccinated group were generally much lower than expected based on their proportion of the total population.Throughout 2022, SC rates remained about 1.5 times higher for women that were unvaccinated before SC compared with those that were vaccinated before SCConclusionsIn the Czech Republic, SC rates were substantially lower for women vaccinated against COVID-19 before SC than for those who were not vaccinated. These hypothesis-generating and preliminary results call for further studies of the potential influence of COVID-19 vaccination on human fecundability and fertility.Unfortunately, the potential influence on reproductive health was not assessed in randomized preauthorization trials of COVID-19 vaccines The Czech Republic is one of the few countries where nationwide birth data are available for women who were vaccinated or unvaccinated for COVID-19, It is possible that more women who wished to become pregnant, i.e., achieve SC, chose not to be vaccinated, and/or that more women who did not plan to become pregnant opted for vaccination. MechanismsVaccination may be associated with menstrual pain and changes in menstrual flow and cycle lengthDirect effects of Pfizer on the ovarian follicle were reported recently.https://drjohncampbell.co.uk Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices

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About

Hello Everyone, My name is John Campbell and I am a retired Nurse Teacher and former clinical nurse based in England. I also do some teaching in Asia and Africa when time permits. These videos are to help students to learn the background to all forms of health care. My PhD focused on the development of open learning resources for nurses nationally and internationally. LinkedIn profile, https://www.linkedin.com/in/dr-john-campbell-5256223b/ Twitter, https://twitter.com/Johnincarlisle Disclaimer; These media including videos, book, e book, articles, podcasts are not peer-reviewed. They should never replace individual clinical judgement from your own health care provider. No media-based material on this channel is suitable for using as professional medical advice. All comments are also for educational purposed only and must never replace advice from your own health care provider

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  • Creator
    Campbellteaching
  • Years Active
    2026
  • Episodes
    781

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