AudioScholar Infectious Disease Weekly

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Infectious Disease — a weekly podcast briefing of the most significant peer-reviewed infectious disease literature, synthesized from PubMed and delivered as ~10-minute audio. For practicing physicians. Generated by AudioScholar at audioscholar.cc.

  1. 2d ago

    This Week in Infectious Disease — Oct 30, 2026

    Editor's Pick: Cefepime-Zidebactam for Infections Caused by Carbapenem-Resistant Gram-Negative Bacteria, Including Metallo-β-Lactamase Producers: A Phase 2, Open-Label, Single-Arm, Multicenter Study (Clinical Infectious Diseases, 2026) This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice. Welcome to This Week in Infectious Disease. This week we're covering 10 notable papers spanning treatment of carbapenem-resistant gram-negative infections, diagnostic tools for endocarditis and joint infection, and sexually transmitted infections, HI… This week's papers: 1. Cefepime-Zidebactam for Infections Caused by Carbapenem-Resistant Gram-Negative Bacteria, Including Metallo-β-Lactamase Producers: A Phase 2, Open-Label, Singl… — Clinical Infectious Diseases 2026 2. Cefiderocol for the treatment of bloodstream infection due to MBL-producing Enterobacterales: a single-center retrospective cohort. — International Journal of Antimicrobial Agents 2026 3. Gram-Negative Bacterial Resistance. — New England Journal of Medicine 2026 4. Performance of the recent Duke criteria versions in patients with suspected infective endocarditis and sufficient cardiac imaging: The more things change, the… — Clinical Infectious Diseases 2026 5. External Validation of the PACTO Risk Score for Infective Endocarditis in Patients With Coagulase-Negative Staphylococcal Bacteremia: A Multicenter Cohort Stud… — Open Forum Infectious Diseases 2026 6. State-of-the-Art Review: Native Joint Septic Arthritis Epidemiology, Pathogenesis, Microbiology, Diagnosis, Management, and Outcomes. — Clinical Infectious Diseases 2026 7. Antenatal Screening for Sexually Transmitted Infections to Reduce Preterm Birth or Low Birthweight (Philani Ndiphile Study): A Randomized 3-Group Trial. — Clinical Infectious Diseases 2026 8. Does pre-treatment with doxycycline improve the efficacy of combination minocycline and metronidazole for macrolide-resistant Mycoplasma genitalium infections? — Antimicrobial Agents and Chemotherapy 2026 9. Virological outcomes, resistance profile and viral evolution of lenacapavir-based regimens in heavily treatment-experienced people: data from the PRESTIGIO Reg… — Journal of Antimicrobial Chemotherapy 2026 10. Impact of a large measles outbreak associated with transmission in the Americas and Canada's loss of measles elimination status: descriptive cohort study. — BMJ 2026 Listen at https://audioscholar.cc/episode/2uw78qh5pt

  2. Oct 24

    This Week in Infectious Disease — Oct 23, 2026

    Editor's Pick: Oropouche virus infection in pregnant women in Rio de Janeiro, Brazil: a prospective cohort study (The Lancet Infectious Diseases, 2026) This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice. Welcome to This Week in Infectious Disease. This week we're covering 10 notable papers spanning emerging and severe invasive infections, viral hepatitis and HIV policy and care, and the shifting ground of sexually transmitted infection prevention and… This week's papers: 1. Oropouche virus infection in pregnant women in Rio de Janeiro, Brazil: a prospective cohort study. — The Lancet Infectious Diseases 2026 2. Predictors and Patterns of Metastatic Candidozyma auris Infection, Spain, 2016-2024. — Emerging Infectious Diseases 2026 3. Five-Biomarker Definition for Hypervirulent Klebsiella pneumoniae Bloodstream Infection and Abscess Complications, Japan, 2022-2024. — Emerging Infectious Diseases 2026 4. Not All Extrapulmonary Tuberculosis Is Equal: Site-Specific Mortality in a National Indian Cohort. — Clinical Infectious Diseases 2026 5. Projected Effect of 2026 Federal Changes to the Childhood Immunization Schedule on Chronic Hepatitis B Virus Infections in the United States. — Annals of Internal Medicine 2026 6. Cost-Effectiveness of HCV Screening in Emergency Departments Using DETECT Hep C Trial Results. — JAMA Internal Medicine 2026 7. Long-term Effectiveness, Treatment Persistence, and Timing of Virological Failure With Long-Acting Cabotegravir Plus Rilpivirine in Real-World HIV Care: RELATI… — Open Forum Infectious Diseases 2026 8. How do we monitor doxy-PEP impact and when should we consider revisiting guidelines? — PLOS Medicine 2026 9. Enabling Ciprofloxacin Resistance-Guided Therapy for Neisseria gonorrhoeae: Aligning Diagnostics, Regulation, Guidelines, and Reimbursement. — Clinical Infectious Diseases 2026 10. Updated UK good practice recommendations for outpatient parenteral antimicrobial therapy (OPAT): ensuring quality of care and antimicrobial stewardship in an e… — Journal of Antimicrobial Chemotherapy 2026 Listen at https://audioscholar.cc/episode/2mcy8tg8an

  3. Oct 17

    This Week in Infectious Disease — Oct 16, 2026

    Editor's Pick: Long-Acting HIV Therapy in African Adults with Adherence Challenges (New England Journal of Medicine, 2026) This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice. Welcome to This Week in Infectious Disease. This week we're covering 10 notable papers spanning long-acting HIV therapy, the management of catheter and enterococcal bloodstream infections, and several studies that put long-held treatment and preventi… This week's papers: 1. Long-Acting HIV Therapy in African Adults with Adherence Challenges. — New England Journal of Medicine 2026 2. Risk Factors and Therapeutic Consequences of Virologic Failure With Long-Acting Cabotegravir Plus Rilpivirine in the Dat'AIDS Cohort. — Clinical Infectious Diseases 2026 3. Randomized Trial Comparing Minocycline-EDTA-Ethanol Lock to Standard-of-Care Antibiotic Lock for Management of Central Line-Associated Bloodstream Infection. — Clinical Infectious Diseases 2026 4. Recurrent and Relapsing Catheter-Related Bloodstream Infections in Patients Requiring Long-term Vascular Access. — Clinical Infectious Diseases 2026 5. Antibiotic Stewardship, Resistance, and Mortality in Vancomycin-Resistant Enterococcus: A Quasi-Experimental Study of Linezolid Restrictions. — Clinical Infectious Diseases 2026 6. Daptomycin for enterococcal bloodstream infections and endocarditis: reconciling clinical evidence, susceptibility testing, and regulatory frameworks. — The Lancet Infectious Diseases 2026 7. Outpatient Antibiotic Fills and 30-Day Readmission Following Patient-Directed Discharge in Drug Use-Associated Infective Endocarditis in a National Medicaid Co… — Clinical Infectious Diseases 2026 8. Efficacy, safety, and immunogenicity of a nine-valent vaccine (ExPEC9V) for the prevention of invasive Escherichia coli disease in older adults: a phase 3, ran… — The Lancet Infectious Diseases 2026 9. Omitting the Eradication Phase of Treatment of Adults with Melioidosis: A Pilot, Single-Center Randomized Controlled Trial. — Open Forum Infectious Diseases 2026 10. Empirical Antifungal Treatment of Critically Ill Patients With Influenza-Associated Acute Respiratory Distress Syndrome: A Bayesian Perspective. — Clinical Infectious Diseases 2026 Listen at https://audioscholar.cc/episode/ywb9yg74ff

  4. Oct 10

    This Week in Infectious Disease — Oct 9, 2026

    Editor's Pick: Evidence of artemisinin partial resistance in Zambia: a molecular epidemiology and clinical study (The Lancet Infectious Diseases, 2026) This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice. Welcome to This Week in Infectious Disease. This week we're covering 10 notable papers spanning global threats to antimicrobial efficacy and health systems, antimicrobial stewardship and duration of therapy, new diagnostics for fungal and mycobacteri… This week's papers: 1. Evidence of artemisinin partial resistance in Zambia: a molecular epidemiology and clinical study. — The Lancet Infectious Diseases 2026 2. Hospital-based prevalence of culture-confirmed melioidosis among high-risk patients in India, 2023-25: a multicentre prospective study. — The Lancet Global Health 2026 3. HIV service delivery after the PEPFAR and USAID HIV funding withdrawal in Uganda and Zimbabwe: an interrupted time-series study. — The Lancet Global Health 2027 4. A Systematic Review and Network Meta-analysis of Empirical Antibiotics for Complicated Urinary Tract Infections. — Open Forum Infectious Diseases 2026 5. Shorter Antibiotic Duration for Pseudomonas Bacteremia: A Call for Future Trials. — Clinical Infectious Diseases 2026 6. Antibiotic exposure and the emergence of multidrug resistant bacteria in patients with liver cirrhosis: A prospective cohort study. — Clinical Infectious Diseases 2026 7. Performance of the Urinary MycoMEIA Aspergillus Assay as an Aid to Diagnose Invasive Aspergillosis. — Clinical Infectious Diseases 2026 8. Tongue Swab Mycobacterium tuberculosis Quantitative Polymerase Chain Reaction for Community Screening of Asymptomatic Tuberculosis Versus Clinic-Based Triage o… — Clinical Infectious Diseases 2026 9. Effect of Fluvoxamine and Metformin for Fatigue in Patients With Long COVID : An Adaptive Randomized Trial. — Annals of Internal Medicine 2026 10. Efficacy and safety of switching to once-daily oral doravirine plus raltegravir in virologically suppressed people with HIV-1: a randomized, open-label, multic… — Journal of Antimicrobial Chemotherapy 2026 Listen at https://audioscholar.cc/episode/m6tjh3xnhr

  5. Oct 3

    This Week in Infectious Disease — Oct 2, 2026

    Editor's Pick: Risk Factors Associated With Positive Intraoperative Valve Tissue Cultures and the Subsequent Impact on Infective Endocarditis Management and Outcomes (Open Forum Infectious Diseases, 2026) This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice. Welcome to This Week in Infectious Disease. This week we're covering 10 notable papers spanning vaccine-preventable disease and the fragility of immunisation programmes, mycobacterial infection from pharmacokinetics to trial design, and the fine-tuni… This week's papers: 1. Nationwide Surveillance and Control Measures during Large Measles Outbreak, Bangladesh, 2026. — Emerging Infectious Diseases 2026 2. The Impermanence of Public Health Gains-Lessons Learned from Measles Resurgence, Bangladesh, 2026. — Emerging Infectious Diseases 2026 3. Immunogenicity and safety of BPZE1, an intranasal live attenuated pertussis vaccine, evaluated with and without tetanus-reduced diphtheria-acellular pertussis… — The Lancet Infectious Diseases 2026 4. Prevalence of Congenital Cytomegalovirus Infection in a CMV-Endemic Ugandan Population. — Open Forum Infectious Diseases 2026 5. Inflammation Precedes Paradoxical Reactions in HIV-Negative Patients With Pulmonary Tuberculosis. — Open Forum Infectious Diseases 2026 6. Pulmonary pharmacokinetics and lesion penetration of antimicrobials in patients with nontuberculous mycobacterial disease. — Antimicrobial Agents and Chemotherapy 2026 7. Symptom-agnostic endpoints in tuberculosis vaccine efficacy trials. — The Lancet Global Health 2026 8. Risk Factors Associated With Positive Intraoperative Valve Tissue Cultures and the Subsequent Impact on Infective Endocarditis Management and Outcomes. — Open Forum Infectious Diseases 2026 9. OmpK36 Alterations Are Associated with Reduced Imipenem/Relebactam Susceptibility in KPC-2-Producing Klebsiella pneumoniae, with Dose-Dependent Restoration at… — International Journal of Antimicrobial Agents 2026 10. Reexamining Novel Risk Factors for Community-Acquired Clostridioides difficile: A Multimodal Approach. — Open Forum Infectious Diseases 2026 Listen at https://audioscholar.cc/episode/q25cu42yd5

  6. Sep 26

    This Week in Infectious Disease — Sep 25, 2026

    Editor's Pick: Effectiveness of timely hepatitis B birth dose vaccination to prevent mother-to-child transmission in Ethiopia (Clinical Infectious Diseases, 2026) This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice. Welcome to This Week in Infectious Disease. This week we're covering 10 notable papers spanning vaccine effectiveness and prevention across very different settings, global diagnostics and elimination programmes for tuberculosis and schistosomiasis, a… This week's papers: 1. Influenza vaccine effectiveness against influenza A-associated hospitalization and severe in-hospital outcomes among adults in the United States, 2024-2025. — Clinical Infectious Diseases 2026 2. Source Control in Pseudomonas aeruginosa Bloodstream Infections: An Overlooked Pillar in Reducing 30-Day All-Cause Mortality. — Open Forum Infectious Diseases 2026 3. Effectiveness of timely hepatitis B birth dose vaccination to prevent mother-to-child transmission in Ethiopia. — Clinical Infectious Diseases 2026 4. Long-term Antiretroviral Therapy and Anogenital Cancer Risk. — Clinical Infectious Diseases 2026 5. Diagnostic performance and testing costs of pooled testing for molecular detection of tuberculosis in seven countries: a prospective, observational, diagnostic… — The Lancet Global Health 2027 6. Ethical Priorities for Candida auris Screening in Solid Organ Transplantation. — Clinical Infectious Diseases 2026 7. Safety of the M72/AS01 Tuberculosis Vaccine in People Living With HIV: A Systematic Review and Meta-Analysis. — Open Forum Infectious Diseases 2026 8. A clinical prediction model to support risk-adapted fibrinogen monitoring during tigecycline therapy: multicenter development and validation. — International Journal of Antimicrobial Agents 2026 9. Glecaprevir/Pibrentasvir Concentrations in the Breastmilk of Lactating Women. — Clinical Infectious Diseases 2026 10. Burden of schistosomiasis in Ethiopia following 10 years of preventive chemotherapy: a national cross-sectional geostatistical survey. — The Lancet Global Health 2026 Listen at https://audioscholar.cc/episode/nc9q6qbkgm

  7. Sep 19

    This Week in Infectious Disease — Sep 18, 2026

    Editor's Pick: Short or Long Antibiotic Regimens in Orthopedics (New England Journal of Medicine, 2026) Welcome to This Week in Infectious Disease. This week we're covering 10 notable papers spanning treatment de-escalation and shorter, simpler regimens; the economics of doing the right thing; and new diagnostics for tuberculosis, hepatitis C and invas… This week's papers: 1. Short or Long Antibiotic Regimens in Orthopedics. — New England Journal of Medicine 2026 2. Switch to injectable cabotegravir-rilpivirine given every 8 weeks in adolescents living with HIV with virological suppression in sub-Saharan Africa (LATA): a r… — The Lancet 2026 3. A randomized controlled trial evaluating a novel individualized treatment strategy for carbapenem-resistant Gram-negative bacteria infections. — International Journal of Antimicrobial Agents 2026 4. Economic Outcomes of Dalbavancin versus Standard Therapy in Staphylococcus aureus Bacteremia in the DOTS Randomized Clinical Trial. — Clinical Infectious Diseases 2026 5. Health Economic Analysis of the AMBITION Protocol for Human Immunodeficiency Virus-Associated Cryptococcal Meningitis in the United States. — Clinical Infectious Diseases 2026 6. Meropenem-Colistin Combination Mitigates Porin-Associated Carbapenem Resistance Development in Ertapenem-Mono-Resistant Enterobacterales. — The Journal of Infectious Diseases 2026 7. Evaluating metagenomic sequencing as a stool-based diagnostic in children with presumptive TB in Uganda. — Clinical Infectious Diseases 2026 8. Plasma Microbial Cell-Free DNA Sequencing for the Diagnosis of Chronic Disseminated Candidiasis in Patients with Hematologic Malignancies. — Open Forum Infectious Diseases 2026 9. A novel decentralized rapid test for detection of HCV antigens using smart polymer technology: a prospective multinational study. — The Journal of Infectious Diseases 2026 10. Management of Mycobacterium bovis Meningitis: The Case for Adjunctive Empirical Therapy. — Open Forum Infectious Diseases 2026 Listen at https://audioscholar.cc/episode/9fj8k7hej9

  8. Sep 12

    This Week in Infectious Disease — Sep 11, 2026

    Editor's Pick: Effectiveness and safety of cefazolin vs antistaphylococcal penicillins for methicillin-susceptible Staphylococcus aureus bacteremia: a multicenter real-world evaluation using the international TriNetX database (Antimicrobial Agents and Chemotherapy, 2026) Welcome to This Week in Infectious Disease. This week we're covering 10 notable papers spanning antibacterial therapy and resistance, antimicrobial and antifungal dosing decisions, and prevention — from influenza vaccines to pre-exposure prophylaxis… This week's papers: 1. Effectiveness and safety of cefazolin vs antistaphylococcal penicillins for methicillin-susceptible Staphylococcus aureus bacteremia: a multicenter real-world… — Antimicrobial Agents and Chemotherapy 2026 2. Advances in the diagnosis and management of skin and soft tissue infections. — BMJ 2026 3. Immunogenicity and safety of an MF59-adjuvanted cell-derived higher-dose quadrivalent influenza vaccine (aQIVc) in adults aged 50 years or older: a phase 3 ran… — The Lancet Infectious Diseases 2026 4. Relationship between Antibiotic Prescription and Survival in Hospice. — Clinical Infectious Diseases 2026 5. Effectiveness of benznidazole in the treatment of Chagas disease in children and adults: a long-term retrospective cohort study. — Antimicrobial Agents and Chemotherapy 2026 6. Aztreonam-avibactam Activity against Enterobacterales from Asia Pacific and Latin American Medical Centres: Summary of 5 years of Surveillance prior to Clinica… — International Journal of Antimicrobial Agents 2026 7. Repeated emergence and fitness heterogeneity of KPC-33 in ST11 Klebsiella pneumoniae under ceftazidime-avibactam pressure. — Antimicrobial Agents and Chemotherapy 2026 8. Development of a dosing algorithm integrating pharmacogenetic markers and inflammation for individualization of initial voriconazole maintenance doses. — Antimicrobial Agents and Chemotherapy 2026 9. Clinical pharmacology and therapeutic considerations of isavuconazole in special populations: a narrative review. — International Journal of Antimicrobial Agents 2026 10. Effect of Pregnancy on Intracellular Tenofovir Diphosphate Exposure and Thresholds following Oral Emtricitabine-Tenofovir Disoproxil fumarate Pre-Exposure Prop… — The Journal of Infectious Diseases 2026 Listen at https://audioscholar.cc/episode/faa6dkezcm

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Infectious Disease — a weekly podcast briefing of the most significant peer-reviewed infectious disease literature, synthesized from PubMed and delivered as ~10-minute audio. For practicing physicians. Generated by AudioScholar at audioscholar.cc.

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