UC San Diego (Audio)

UCTV

Programs from the University of California, San Diego.

  1. 4d ago

    Ethical Sourcing in Health Data Supply Chains: Considerations for ML/AI Training

    Health data affects artificial intelligence in important ways. Camille Nebeker, Ed.D., M.S., UC San Diego, explains why ethically sourced data is foundational to building trustworthy, AI-ready health data repositories. Nebeker examines how ethical sourcing applies across the full data lifecycle, including consent, governance, transparency, data quality, privacy, stewardship, and community engagement. She also shows how ideas from supply chain management and value sensitive design help teams identify ethical tensions and improve decision-making. This work helps explain why ethics cannot be added at the end of AI development and points toward more accountable data practices that support public trust and stronger downstream performance. Series: "Exploring Ethics" [Science] [Show ID: 41368]

    24 min

  2. Jun 5

    Stem-Cell Aging and Pathways to Precancer Evolution

    Pre-cancer and cancer can begin when stressed blood-forming stem cells lose their normal controls. Catriona Jamieson, M.D., Ph.D., UC San Diego, explains how inflammation-linked editing enzymes, repetitive elements in the genome, and stem cell stress shape the progression from myeloproliferative neoplasms to acute myeloid leukemia. Jamison examines how spaceflight accelerates stem cell aging, how some astronauts mobilize a resilient regenerative stem cell population, and how tumor organoids in space help reveal drug responses by activating the enzyme ADAR1. This work helps explain how cancer starts, why it can return, and how space-based research may speed the development of therapies that stop malignant stem cells before disease advances. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 41473]

    22 min

  3. May 30

    From Electronic Health Records to Space Medicine: Building the Future of Space Healthcare

    Space healthcare depends on connected health data that can follow people wherever care happens. Peter DeVault, Epic, explains how electronic health record tools built for hospitals, labs, and patients can also support healthcare in space. DeVault describes patient-facing tools like MyChart, interoperability across health systems, structured genomics and pharmacogenomics in the patient record, and Cosmos, Epic’s patient data aggregation platform with about 300 million longitudinal records. He also examines AI capabilities that can generate possible future health scenarios and expand to telemetry and molecular data collected before, during, and after a mission. This work helps explain how records, data sharing, and predictive tools could support astronaut health and resilience and why those capabilities may be necessary for the future of space medicine. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 41481]

    12 min

  4. May 25

    From Orbital Experiments to Curing Earthling Diseases: How Space-Enabled Biotechnology is Advancing Neuroscience on Earth

    Brain aging and disease research can gain new insights from space. Aline M.A. Martins, Ph.D., UC San Diego, explains how neuroscience studies in space use brain organoids, proteomics, and single-cell analysis to understand cognition decline, space-induced neurosenescence, and disease-related changes. Martins examines molecular markers of senescence, mitochondrial impairment, and neuroinflammation in organoid models, including Rett syndrome, while also comparing how space affects organoids of different ages. She shows that space can accelerate aging-related changes and affect cell types differently, helping clarify how space biology may speed drug discovery and reveal biomarkers for disease. This work helps explain how space research can inform treatments on Earth and points toward faster preclinical testing and broader understanding of brain disease. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 41478]

    10 min

  5. May 23

    Climate Faith and Collective Responsibility with Bill McKibben

    Environmentalist and author Bill McKibben has helped shape how the world understands climate change. In this conversation with Marco Werman, host of The World, McKibben offers a clear-eyed look at the climate crisis and the solutions that could help reduce the damage of a warming planet. As part of the Burke Lectureship at UC San Diego, McKibben also explores the moral and spiritual questions at the heart of climate change. More than three decades after The End of Nature brought climate change to a broad audience, his work continues to connect science, ethics, and grassroots action, including the global climate campaign 350.org and the fossil fuel divestment movement. Series: "Burke Lectureship on Religion and Society" [Humanities] [Science] [Show ID: 41265]

    1h 27m

  6. May 22

    Extreme Events in California’s Changing Climate

    How does global warming connect to the extreme weather people experience close to home? Drawing on the work of the Weather Extremes and Climate Impacts Analytics group, Sasha Gershunov of Scripps Institution of Oceanography outlines the accelerating warming trend, the role of fossil fuels and carbon dioxide, and the greenhouse effect, and how it relates to extreme weather. He also traces key milestones in climate science, including the long-term carbon dioxide measurements begun by Charles David Keeling. The discussion then turns to how climate change may affect heat waves, floods, droughts, storms, wildfires, and sea level rise. Series: "Osher UC San Diego Distinguished Lecture Series" [Science] [Show ID: 41412]

    1h 5m

  7. May 18

    Microgravity at Scale: Turning Insight into Impact

    Microgravity can change biological systems in ways that may open new paths for biomedical research and commercialization in space. Twyman Clements, Space Tango, explains how “middleware” helps connect research use cases with space infrastructure by adapting terrestrial processes and supply chains for a spaceflight environment. Clements examines how long-duration microgravity creates different physical conditions, how Space Tango packages experiments into flight-ready lab systems, and how commercial space stations and reentry systems could help increase scale, throughput, and production value. He also points to more robotic systems that could support on-orbit sampling, imaging, and experiment assembly. This work helps explain how space-based biomedical research could move beyond small experimental missions and toward more practical, scalable platforms for discovery and development Series: "Stem Cell Channel" [Science] [Show ID: 41480]

    7 min

  8. May 15

    Leveraging Space

    Stem cell health in space matters for astronaut health and cancer research. Jessica Pham, UC San Diego, explains how spaceflight shapes normal hematopoietic stem cells and cancer stem cells through nano bioreactor studies, astronaut blood analysis, and tumor organoid work in low-Earth orbit. Pham examines increased cycling and reduced dormancy in space, reduced self-renewal after return, and ongoing research on cancer stem cells and their microenvironment, helping clarify how stem cells respond to spaceflight. This work helps explain how space conditions may change stem cell fitness over time and points toward a better understanding of astronaut health, long-duration missions, and cancer stem cell behavior. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 41477]

    9 min
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About

Programs from the University of California, San Diego.

Information

  • Creator
    UCTV
  • Years Active
    2011 - 2026
  • Episodes
    215
  • Rating
    Clean
  • Copyright
    © Copyright 2024 Regents of the University of California
  • Show Website
    UC San Diego (Audio)

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