One common thread for clients with hormone issues is post birth control syndrome that can rear it’s ugly head years later. Wait… did you just say post birth control syndrome? What the heck is that?!?! It’s a very real issue that results from being currently on or having taken birth control pills (BCPs) — even if it was 10, 15 or 20 years ago! What most people don’t know is that hormones (like estrogen) are detoxified by your liver to be removed from active circulation. They also don’t realize that BCPs essentially shut down communication between your brain and your ovaries. Because your body is ONE system, that single statement alone should grab your attention. No doctor ever told me for the ten years that I took BCPs that I was effectively shutting down that very powerful and necessary hormonal feedback loop! Since hormones aren’t my area of expertise, I reached out to my close friend — Dr. Jolene Brighten. She knows her stuff and can go toe-to-toe (because she’s a total research geek) on all things hormones. Before we head into the podcast, make sure to subscribe to my podcast on iTunes!!! And if you love everything you hear, I’d seriously love if you headed over there to leave a review on iTunes so that new listeners see just how valuable this conversation is! How Post Birth Control Syndrome Affects Liver Detoxification Years Later with Dr. Jolene Brighten SHOW NOTES: Dr. Jolene’s Website Dr. Jolene’s Post-Birth Control Awareness Week (REGISTER NOW) Beyond The Pill BOOK (coming in January 2019) TRANSCRIPT Jennifer: I have a very special episode for you today. I know you are used to me talking all by myself, but I felt incredibly compelled today to have a guest join me. In breaking the tradition of season four, I would love the opportunity to welcome Dr. Jolene Brighten. This is her first time ever to the Gluten Free School Podcast. She is a functional medicine naturopathic medical doctor and the founder of Rubus Health, a women’s medical clinic that specializes in women’s hormones. She is the number one expert in a condition called Post Birth Control Syndrome. She also talks a lot about the long-term side effects associated with hormonal contraceptives. Now here’s the thing — If you’re a man and you’re listening to this and you’re like, “What, post birth control syndrome? I’m out.” You know what? You probably know a woman in your life who is experiencing this, and this could be really good information for her, and just also in general. There’s a lot of stuff going on with birth control that we need to be aware of, and the consequences down the road even when it’s long been in your rearview mirror. But today I want to talk about how that directly affects estrogen metabolism. So Dr. Jolene, thank you so much for joining us! Dr. Jolene: Hey there. Thanks so much for having me! Jennifer: I don’t consider myself a hormone expert. I know that because you’re dealing with all of these issues, and birth control is essentially a way of shutting off the connection between your brain and your ovaries, correct? Dr. Jolene: Totally. That’s the number one mechanism of action is to flood the system with so many hormones that your brain says, “Hey ovaries, we’re all good, so let’s not signal to them.” So your brain and your ovaries stop talking. This means that there is no ovulation, which seems like a perfect solution if you don’t want to get pregnant. That’s until you find out that there’s a whole lot more to this story. Lesser Known Liver Side Effects From Post Birth Control Syndrome Jennifer: We know that birth control may be a factor for a lot of women. I have a lot of clients who they’ve either taken it in the past. Or they are still taking it now because they don’t want to get pregnant, but they’re in that committed relationship. So for anybody listening to this who’s like, “Are we talking about things that not might be cool for me?” A lot of the women I work with are married, they’re in committed relationships, but they were told that having children now might not be a good idea because of having previous traumatic births in the past and other reasons. But here’s the thing — How we metabolize estrogen is really important. Birth control pills especially mess with that, so can you talk to us a little bit about the role that estrogen plays and how the pill can really screw that up? Dr. Jolene: I do want to say that if you’re a woman who’s using hormonal birth control, it’s not my aim to shame you or freak you out. But I think that you deserve all the information so you can care for your body. It’s very much my philosophy that it’s not my body, it’s your body. Whatever you choose, it’s my job as a physician to support that. And so here’s the really important thing to understand, and I thank you for starting this conversation, Jen. You said, “I want to talk about the liver” and here we are! We did not diagnose liver tumors in women to the extent that we do now, not until the hormonal birth control was introduced did we start seeing lots of lumps on your liver, so benign liver tumors are actually very common. That’s a structural change happening to the liver because of being on hormonal contraceptives. Now, your liver does so many wonderful things, and one of those things is detoxification, so your natural estrogen has to go through liver detoxification. Phase one and phase two detoxification, and there’s methylation required for all of that as well. And so when you’re on hormonal birth control, any oral estrogen also has to pass through the same detox mechanisms. The problem is not their structural alterations — yes, these liver tumors are benign. We do see an increase in liver cancer, but, for the most part, the liver tumors are benign. But, keep in mind, a structural change means this tissue is no longer working the way that it once was, so now we’ve inhibited detox capacity in that way. In addition to that, these liver tumors rupture very easily. Your liver is pumping so much blood that while a doctor may say it’s benign as in you don’t have cancer, it’s certainly not benign if you’re walking around taking the pill, you don’t know you have a liver tumor, you end up in a motor vehicle accident, or maybe you’re playing football. But you have some kind of trauma to the abdomen, they can rupture and lead to a bleed. Nutritional Concerns Resulting Even Though You Stopped The Pill So that’s one way that the birth control can impact your liver, but in addition to that, you have to take enough estrogen to shut down the brain from talking to the ovaries. When you do that, you’re going to overwhelm the system with estrogen. As you do that, the liver is going to struggle in other ways to be able to detoxify environmental toxins. So think about it. You’re walking around an environment that you don’t have full control over. You already have xenoestrogens hitting you left and right. These are chemical compounds that are in our environment. They’re toxins that alter your hormonal function as it is, but also make extra work for your liver. These come in personal care products and receipts, and just about everywhere. In addition to that, hormonal birth control is depleting nutrients. The very nutrients you need to run your phase one and phase two liver detox, as well as run the COMT pathway which is a gene that helps with estrogen methylation. Specifically, if you’re lacking magnesium, which just about everybody’s diet is lacking magnesium, hormonal birth control depletes magnesium, you can be in big trouble when it comes to that liver detoxification. I know that is a lot of information there, but does that make sense? Jennifer: It does. And fortunately, I have recently shared in a podcast, I believe it’s one or two before this, so if you guys are listening sequentially, you have already heard all about the liver detoxification pathways — phase one and phase two — so you are familiar with what we are talking about. I’m really glad this is able to overlap. I’m a little taken back, to be honest with you. I was on birth control pills for 10 years. I never knew that you could have these structural changes within your liver. That’s actually really alarming, and so anybody who’s listening to this, that’s, I guess that’s something really pretty serious you have to consider. So if you go off the birth control, do they go away? Dr. Jolene: I did the pill for 10 years too, by the way, that’s why I’m like, “Let’s not be shaming anybody.” But the thing about the liver is those hepatocytes, so the liver cells, they are amazing. They can regenerate themselves. It depends on underlying conditions, individualized factors like are you still having exposure to other elements, but yes, some of these tumors can go away. The body over time can break them down and can heal. Things like milk thistle can certainly help. That’s an herb that helps the hepatocytes regenerate. We see that milk thistle can help in conditions like cirrhosis, which is due to alcoholism, so it is something that is very startling. Why We Need More Research On How Birth Control Pills Affect Women The research for women after stopping birth control pills isn’t the greatest. Researchers are not really looking at it like, “Oh, how long do these tumors take to resolve?” They’re more just documenting what happened. We also have to understand that research is done through the lens of a healthy woman… not those who are sick. Hormonal birth control was never designed for a diseased state to begin with. It was the first pharmaceutical introduced that you didn’t have to have a diagnosis. It was just you just had to be fertile. With that, it was really designed for a healthy, fertile female, however we know that not everybody is made exactly the