Life in Voxels

POSITROPTICS LLC
  • 5.0 (1)
  • Life Sciences
  • Updated Monthly

Life in Voxels explores the science, technology, and people shaping the future of medical imaging. Through conversations with researchers, engineers, clinicians, and innovators, the podcast examines how advances in imaging instrumentation, computational methods, artificial intelligence, quantitative imaging, and molecular imaging move from scientific ideas toward practical applications. You may watch the vidcast version on Life in Voxel's YouTube channel: https://www.youtube.com/@lifeinvoxels

Episodes

  1. Sep 1

    From Conceptualization to Prototyping of Positron Emission Tomography Systems

    How does a PET scanner progress from an initial scientific concept to a functioning imaging system? In the inaugural episode of Life in Voxels, hosts Nicolas A. Karakatsanis, Georgios Soultanidis, and Ezzat Elmoujarkach are joined by instrumentation scientists Fiammetta Pagano of the Institute for Instrumentation in Molecular Imaging (i3M), Valencia, Spain, and David Sánchez of Oncovision SA, Valencia, Spain. Their conversation follows the development of PET instrumentation from scientific need and detector design through system integration, calibration, simulation, and image reconstruction, using the Ultra-High-Performance Brain PET (UHB-PET) prototype as a real-world example. The discussion explores why dedicated brain PET systems remain scientifically important; how semi-monolithic detector architectures work; why depth-of-interaction information matters in compact PET geometries; how machine learning can estimate gamma-ray interaction positions; how multiplexing helps translate laboratory detector concepts into scalable systems; and what changes when hundreds of detector components are integrated into a complete scanner. The conversation also goes behind the scenes of UHB-PET calibration and commissioning at Weill Cornell Medicine, examining energy and timing calibration, detector positioning, normalization, system troubleshooting, experimentally informed Monte Carlo simulation, image reconstruction, and the recovery of complex detector events. Finally, the guests discuss the increasingly close relationship between hardware and software innovation and what the next generation of PET instrumentation may look like. Hosts Nikolaos A. Karakatsanis — Department of Radiology, Weill Cornell Medicine Georgios Soultanidis — Biomedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai Ezzat Elmoujarkach — Department of Radiology, Weill Cornell Medicine Guests Fiammetta Pagano — Institute for Instrumentation in Molecular Imaging (i3M), Valencia, Spain David Sánchez — Oncovision, Valencia, Spain Topics Discussed PET instrumentation • dedicated brain PET • UHB-PET • semi-monolithic detectors • LYSO scintillators • silicon photomultipliers (SiPMs) • depth of interaction (DOI) • time of flight (TOF) • machine learning • detector multiplexing • scanner calibration • system commissioning • GATE Monte Carlo simulation • image reconstruction • inter-crystal scattering • artificial intelligence in detector technology Produced and published by POSITROPTICS LLC. © 2026 POSITROPTICS LLC. All rights reserved. The views expressed by the hosts and guests are their own and do not necessarily represent those of their respective institutions or organizations.

  • 1 Episode

About

Life in Voxels explores the science, technology, and people shaping the future of medical imaging. Through conversations with researchers, engineers, clinicians, and innovators, the podcast examines how advances in imaging instrumentation, computational methods, artificial intelligence, quantitative imaging, and molecular imaging move from scientific ideas toward practical applications. You may watch the vidcast version on Life in Voxel's YouTube channel: https://www.youtube.com/@lifeinvoxels

Information

  • Creator
    POSITROPTICS LLC
  • Years Active
    2026
  • Episodes
    1
  • Rating
    Clean
  • Copyright
    © POSITROPTICS LLC
  • Show Website
    Life in Voxels