Uncharted: The Science Behind Women's Health

Allergy Research Group

Uncharted is a new podcast from Allergy Research Group (ARG) for practitioners and anyone curious about the science of women’s health. In each episode, host Dr. Lara Zakaria sits down with a clinician, researcher or women’s health expert to unpack one question, connect the dots and make the conversation useful in practice and everyday life. The focus for Season 1 is women’s thyroid health. We hope you join us.

Episodes

  1. 5d ago ·  Video

    Why Can Thyroid Labs Look Normal When Symptoms Persist? with Dr. Jaclyn Smeaton (Part 1)

    A thyroid test can fall within the reference range even when someone continues to experience fatigue, brain fog, changes in mood or energy, or other persistent symptoms. That can leave patients and clinicians wondering what the results do and don’t show, as well as what to explore next. In Part 1 of this two-part conversation, host Dr. Lara Zakaria talks with Dr. Jaclyn Smeaton, a naturopathic physician and Chief Medical Officer at Precision Analytical. They discuss what TSH measures, what other thyroid markers can show, how stress physiology may affect thyroid signaling and hormone conversion, and what the cortisol awakening response can tell clinicians about the body’s response to stress. Part 2 continues the discussion with a closer look at cortisol assessment and the relationship between stress physiology and thyroid health. In this episode: What TSH measures and how to interpret it alongside a person’s symptomsWhat free T4, free T3, reverse T3, and thyroid antibodies measureHow stress physiology may affect thyroid signaling and hormone conversionWhat the cortisol awakening response is and how Jaclyn uses it in her clinical workChapter markers: (01:16) - Dr. Jaclyn’s path to women’s health (03:36) - What TSH alone can miss about thyroid function (06:24) - What a broader thyroid panel can include (09:03) - How stress and the HPA axis affect thyroid function (11:14) - What cortisol testing can reveal alongside thyroid labs (12:55) - What the cortisol awakening response measures

  2. Oct 21 ·  Video

    What Is the Gut-Thyroid Connection? with Alisha Knicely

    What does it really mean to “heal your gut,” and how is gut health connected to thyroid function? In this episode of Uncharted, host Dr. Lara Zakaria talks with registered dietitian and functional medicine practitioner Alisha Knicely about the two-way relationship between gut and thyroid health.  Drawing from both her clinical work and her personal experience with Hashimoto’s disease and hypothyroidism, Alisha explains how thyroid function can affect digestion, motility, stomach acid, and nutrient absorption, and how digestive health may influence thyroid health in return. In this episode: The difference between Hashimoto’s disease and hypothyroidismHow low thyroid function may affect digestion, motility, stomach acid, and nutrient absorptionWhy thyroid medication may improve lab results without resolving every symptomHow under-eating may work against healingPractical ways to support digestion through healthy meal habits and nutrient-dense foodsWhen targeted supplements may be considered as part of an individualized planRelevant resources: Understanding Thyroid AutoimmunityThe Thyroid Plateau: Why Symptoms Linger Despite Medication and “Normal” LabsChapter markers: (01:15) - Alisha’s Hashimoto’s and hypothyroidism diagnosis (04:24) - Hashimoto’s vs. hypothyroidism (07:00) - How first-hand experience changed Alisha’s patient approach (08:17) - Explanation of the gut-thyroid connection (12:00) - Lifestyle changes that can help with thyroid and gut health (14:14) - Dietary patterns to try and avoid (15:46) - Approach to targeted supplementation

  3. Oct 14 ·  Video

    What Is the Energy Allocation System? with Dr. Corey Schuler

    Why do so many women with “normal” thyroid labs still feel exhausted, foggy, and unlike themselves? In the first episode of Uncharted, host Dr. Lara Zakaria talks with Corey Schuler, PhD, FNP-C, APHN-BC, CNS, about the Energy Allocation System (EAS): an emerging framework for understanding how the body produces, distributes, and prioritizes energy over time. Together, they explore why symptoms such as fatigue, brain fog, disrupted sleep, and weight changes may persist even when standard thyroid labs fall within conventional reference ranges—and how clinicians and patients can use this perspective to ask better questions and look more closely at the full picture. This conversation introduces the thinking behind EAS and lays the foundation for Uncharted’s first season on women’s thyroid health. In this episode: What the Energy Allocation System is—and why it was developedHow the body’s stress-response, thyroid, and reproductive systems may interact over timeWhy persistent symptoms can occur even when thyroid labs are within conventional rangesWhy TSH is important, but may not always tell the whole clinical storyHow clinicians and patients can begin applying EAS and its questions Relevant resources: Energy Allocation System Chapter markers: (02:15) - Dr. Corey’s background and journey (03:04) - The Energy Allocation System (EAS) in simple terms (04:41) - Why the EAS was created (06:51) - Why the EAS has resonated (07:45) - Hypothetical situation using the EAS lens (12:10) - How EAS changes our understanding of thyroid health (15:59) - How to implement EAS in practice today

Ratings & Reviews

5
out of 5
4 Ratings

About

Uncharted is a new podcast from Allergy Research Group (ARG) for practitioners and anyone curious about the science of women’s health. In each episode, host Dr. Lara Zakaria sits down with a clinician, researcher or women’s health expert to unpack one question, connect the dots and make the conversation useful in practice and everyday life. The focus for Season 1 is women’s thyroid health. We hope you join us.

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