250 episodes

The a16z Podcast discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

a16z Podcast Andreessen Horowitz

    • Technology
    • 4.4, 587 Ratings

The a16z Podcast discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

    Working, Making, Creating in Public... and Private

    Working, Making, Creating in Public... and Private

    with @nayafia @smc90

    Communities are everything, but the word "members" is faceless. What if there's a better, more modern way to understand, support, and design for communities of all kinds -- whether open source, passion economy, or other groups coming together? Nadia Eghbal offers the latest research and insights from her new book, Working in Public: The Making and Maintenance of Open Source Software... but it's not all participatory, and it's not all public, either.

    • 47 min
    GPT-3: What's Hype, What's Real on the Latest in AI

    GPT-3: What's Hype, What's Real on the Latest in AI

    with @smc90 @withfries2

    Given all the recent buzz around the language model GPT-3 -- what is "it", how does it work, where does it fit into the arc of broader tech trends -- what's hype, what's real here? Are we really getting closer to artificial general intelligence? We cover all this and more and discuss broader implications for startups, incumbents, and the future of work too.

    • 33 min
    Taking the Pulse on Medical Device Security

    Taking the Pulse on Medical Device Security

    with @AndreaCoravos, @beauwoods, and @omnivorousread

    Many don’t realize we even need to think about the possibility of security hacks when it comes to things like pacemakers, insulin pumps, and more. But when bits and bytes meet flesh and blood, security becomes literally a life or death concern. So what are the issues and risks we need to be aware of in exposing security vulnerabilities in connected biomedical devices?

    This conversation—with Beau Woods, Cyber Safety Innovation Fellow with the Atlantic Council, part of the I Am The Cavalry grassroots security initiative, Founder/CEO of Stratigos Security; Andy Coravos, co-founder and CEO of Elektra Labs, advisor to the Biohacking Village at DEF CON (both of whom were formerly EIRs at the FDA); and a16z's Hanne Tidnam covers how we should begin to think about addressing these security issues in the biomedical device space. What are the frameworks that should guide our conversations, and how and when (and which!) stakeholders should be incentivized to address these challenges? How did the FDA begin to think about security as part of the safety of all medical devices, including software as a medical device, and how we should think about understanding, monitoring, and updating the security of these devices—from philosophical statements to on-the-ground practical fixes and updates?

    • 23 min
    Journal Club: A New Path to Antibiotic Resistance

    Journal Club: A New Path to Antibiotic Resistance

    With Nathalie Balaban and @lr_bio

    Antibiotic resistance is an urgent problem, but many aspects of how bacteria acquire this ability to evade the drugs designed to target them are still mysterious. On this episode of the a16z bio Journal Club, Lauren Richardson interviews Professor Nathalie Balaban about her group’s research into the conditions that promote antibiotic resistance in patients suffering from life threatening infections and how to prevent it with carefully and rationally selected drug combinations.

    • 17 min
    Cybercrime, Incorporated

    Cybercrime, Incorporated

    with Joel de la Garza, Jonathan Lusthaus, and @omnivorousread

    Cybercrime is unfortunately as evergreen a topic as the problem itself—which is why we’re re-running this popular security episode all about the criminal industry of cybercrime from 2019.

    The idea of the cybercriminal as lone wolf or hobby hacker is no longer much of a reality. Instead, the business of cybercrime looks a lot more like a large, global technology business, with many of the same structures, challenges, and even casts of characters that legitimate businesses have. In this conversation, a16z’s Joel de la Garza, a16z operating partner for information security (formerly CSO of Box and head Citigroup’s Cyber Intelligence Center), and Hanne Tidnam, discuss with Jonathan Lusthaus, Director of the Human Cybercriminal Project at the University of Oxford, the evolution of cybercrime into a sprawling and sophisticated international industry.

    • 36 min
    How Transparent Pricing Drives Healthcare Change

    How Transparent Pricing Drives Healthcare Change

    with @MartyMakary and @julesyoo

    Dr. Marty Makary—surgical oncologist at Johns Hopkins University School of Medicine, and health policy and innovation expert—has long been a passionate advocate for transparent pricing in the healthcare system. We don’t talk enough (or really at all) about price in healthcare, says Makary (instead, we talk about cost). But shedding a light on prices in healthcare—from not just what those prices are but how prices are set and the value we all receive as consumers of the system overall—can help us measure quality in medicine, and be a driver for real behavioral change in the healthcare system, correcting many of the unintended consequences of a fee-for-service system like surprise billing or unnecessary medical procedures.

    In this conversation with a16z General Partner Julie Yoo, Makary and Yoo discuss what price transparency in the healthcare system could really do; how we can "steer" towards the good physicians who are not just highly skilled, but make the right judgment calls based on need and holistic health, not cost; how we might distinguish between high value and low value through medical appropriateness; and how we might gain clinical wisdom from other kinds of scientific discovery beyond randomized controls, especially during the wartime protocol of COVID-19.

    • 29 min

Customer Reviews

4.4 out of 5
587 Ratings

587 Ratings

cali_sci_gal ,

Loving the Journal Club

I’m really enjoying this series. The host is well informed and the guests (and their studies) are really interesting. Keep it up 🙌

wishedItwereBetter ,

Interesting...but not EVERYTHING can be tied to entrepreneurship

Conversations w ppl like Alex Honnold are so great - then it becomes so boring when “then we start talking about revenue....”

Keep the gold, cut the fat. Or “junk mileage” as Alex said. Sometimes it’s smart enough to have these convos w AH folks and global leaders.

alsksjdgh ,

Too political

We get it, you hate the US.

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