The Body of Evidence

Dr. Christopher Labos

Dr. Christopher Labos and guests use the body of evidence to go beyond science and medicine headlines and hype. All to help you develop your critical thinking skills so that when you google your symptoms, you won't believe you're going to die tomorrow. The Body of Evidence is your weekly dose of clarity on complex health topics and the often-sketchy medical information found online. Hosted by cardiologist Dr. Christopher Labos and featuring a rotating cast of co-hosts and guests, this podcast brings you engaging interviews, original reporting, and humour-filled commentaries to help you navigate the world of medicine. Episodes tackle everything from debunking misinformation to exploring the reality of certain conditions to the effectiveness of social media medical trends. With an extensive archive dating back to 2015,The Body of Evidence is your go-to source for understanding science and medicine and developing critical thinking about your health.

  1. Jun 25

    190 – Zone 2 Running: when less exercise might count for more

    Are light runs (Zone 2 runs) better than heavier workouts? Sophie goes on a semi-manic tangent in her most enthusiastic episode yet to answer whether less intense exercise might actually help your fitness level, aerobic threshold and mitochondrial efficiency. Also, Chris tells a funny marathon story and a viewer question tries to fact-check to the fact checkers on whether walking and running burn the same amount of energy.   Become a supporter of our show today either on Patreon or through PayPal! Thank you! http://www.patreon.com/thebodyofevidence/ https://www.paypal.com/donate?hosted_button_id=9QZET78JZWCZE   Email us your questions at thebodyofevidence@gmail.com.   Hosts:     Christopher Labos & Sophie Tseng Pellar Editor:    Robyn Flynn Researcher: Auriane Journet Theme music: "Fall of the Ocean Queen" by Joseph Hackl Rod of Asclepius designed by Kamil J. Przybos Chris' book, Does Coffee Cause Cancer?: https://ecwpress.com/products/does-coffee-cause-cancer   Obviously, Chris is not your doctor (probably). This podcast is not medical advice for you; it is what we call information. References: 1.   Storoschuk, K. L., Moran-MacDonald, A., Gibala, M. J., & Gurd, B. J. (2025). Much Ado About Zone 2: A Narrative Review Assessing the Efficacy of Zone 2 Training for Improving Mitochondrial Capacity and Cardiorespiratory Fitness in the General Population: KL Storoschuk et al. Sports Medicine, 55(7), 1611-1624.  2.   Mølmen, K. S., Almquist, N. W., & Skattebo, Ø. (2025). Effects of exercise training on mitochondrial and capillary growth in human skeletal muscle: a systematic review and meta-regression. Sports Medicine, 55(1), 115-144. 3.   Inglis, E. C., Iannetta, D., Rasica, L., Mackie, M. Z., Keir, D. A., Macinnis, M. J., & Murias, J. M. (2024). Heavy-, severe-, and extreme-, but not moderate-intensity exercise increase V̇o 2max and thresholds after 6 wk of training. Medicine & Science in Sports & Exercise, 56(7), 1307-1316. 4.   McConell, G.K., Wadley, G.D., Le plastrier, K. and Linden, K.C. (2020), Skeletal muscle AMPK is not activated during 2 h of moderate intensity exercise at ∼65% in endurance trained men. J Physiol, 598: 3859-3870. https://doi.org/10.1113/JP277619 5.   Meixner, B., Filipas, L., Holmberg, H. C., & Sperlich, B. (2025). Zone 2 Intensity: A Critical Comparison of Individual Variability in Different Submaximal Exercise Intensity Boundaries. Translational sports medicine, 2025, 2008291. https://doi.org/10.1155/tsm2/2008291 6.   Harber MP, et al. Impact of Cardiorespiratory Fitness on All-Cause and Disease-Specific Mortality: Advances Since 2009. Progress in Cardiovascular Diseases 2017;60(1):11-20. PubMed 28286137 7.   Kodama S, Saito K, Tanaka S, et al. Cardiorespiratory Fitness as a Quantitative Predictor of All-Cause Mortality and Cardiovascular Events in Healthy Men and Women: A Meta-analysis. JAMA 2009;301(19):2024-2035. PubMed 19454641

    44 min
  2. May 28

    186 – Pink Noise

    Pink noise claims it can boost your memory, help your sleep, and treat your ADHD. But how it's studied in a sleep lab is very different from passive listening all night long. Chris and Sophie dive into the evidence to figure out if the influencers pushing pink noise for sleep got it right or if they're simply dreaming.   Become a supporter of our show today either on Patreon or through PayPal! Thank you! http://www.patreon.com/thebodyofevidence/ https://www.paypal.com/donate?hosted_button_id=9QZET78JZWCZE   Email us your questions at thebodyofevidence@gmail.com.   Editor:    Robyn Flynn Researcher: Danielle Kaprelian Theme music: "Fall of the Ocean Queen" by Joseph Hackl Rod of Asclepius designed by Kamil J. Przybos Chris' book, Does Coffee Cause Cancer?: https://ecwpress.com/products/does-coffee-cause-cancer   Obviously, Chris is not your doctor (probably). This podcast is not medical advice for you; it is what we call information. References: The different colours of noise from white to pink to brown: https://www.allure.com/story/what-is-brown-noise-pink-white-sound-therapy The famous 2017 "memory enhancement" study: https://www.frontiersin.org/journals/human-neuroscience/articles/10.3389/fnhum.2017.00109/full A lay summary of the above study: https://time.com/collections/guide-to-sleep/4694555/pink-noise-deep-sleep-improve-memory/ The study showing pink noise might make things worse: https://academic.oup.com/sleep/article/49/5/zsag001/8452884 Dr. F. Perry Wilson's Medscape video series on pink noise: https://www.medscape.com/viewarticle/pink-noise-could-be-wrecking-your-sleep-2026a100039x A 2022 systematic review on overall sleep quality: https://pubmed.ncbi.nlm.nih.gov/34964434/ Memory claims and pink noise: https://www.frontiersin.org/journals/human-neuroscience/articles/10.3389/fnhum.2023.1302836/full Examples of white and pink noise are found here: https://en.wikipedia.org/wiki/File:Pink_noise.ogg and https://en.wikipedia.org/wiki/File:White-noise-sound-20sec-mono-44100Hz.ogg

    41 min
  3. May 21

    185 – Lipoprotein(a): the cholesterol you never heard about until recently

    Lipoprotein(a) or Lp(a) is suddenly all the rage because several drug companies are working on medications to lower this previously resistant form of cholesterol. Almost entirely genetic, unaffected by diet or lifestyle, it has numerous studies linking it to heart disease and aortic valve calcification. But it may not be the ticking time bomb some influencers like to claim.   Become a supporter of our show today either on Patreon or through PayPal! Thank you! http://www.patreon.com/thebodyofevidence/ https://www.paypal.com/donate?hosted_button_id=9QZET78JZWCZE   Email us your questions at thebodyofevidence@gmail.com.   Editor:    Robyn Flynn Theme music: "Fall of the Ocean Queen" by Joseph Hackl Rod of Asclepius designed by Kamil J. Przybos Chris' book, Does Coffee Cause Cancer?: https://ecwpress.com/products/does-coffee-cause-cancer   Obviously, Chris is not your doctor (probably). This podcast is not medical advice for you; it is what we call information. References: The genetic nature of Lp(a) levels: https://pubmed.ncbi.nlm.nih.gov/1386087/ Prevalence of elevated Lp(a) in 500,000 US patients https://pubmed.ncbi.nlm.nih.gov/27659098/ Prevalence of elevated Lp(a) in 2.9 million Chinese adults https://pubmed.ncbi.nlm.nih.gov/40266173/ Prevalence of elevated Lp(a) in the INTERASPIRE study https://pubmed.ncbi.nlm.nih.gov/40436467/ Variation of Lp(a) by sex: https://pubmed.ncbi.nlm.nih.gov/27659098/ One of the many studies linking Lp(a) to cardiovascular disease https://pubmed.ncbi.nlm.nih.gov/33115266/ High Lp(a) and aortic stenosis: https://www.nejm.org/doi/full/10.1056/NEJMoa1109034 FH and Lp(a) https://pubmed.ncbi.nlm.nih.gov/32466883/ The ongoing Lp(a) trials https://familyheart.org/lpa-clinical-trials

    33 min
  4. May 14

    184 – The Meniscus: when in doubt, leave it in

    Meniscectomies were once a very common surgery for knee pain. Then the data happened. Teppo Järvinen from the Finnish Centre for Evidence-Based Orthopaedics (FICEBO) joins Chris to talk about the recent 10-year data from the FIDELITY trial, showing that removing the meniscus in patients with knee pain did not improve symptoms and for a broader discussion about the role and importance of sham surgery and placebo controls in surgical research. He also shows Chris that orthopaedic surgeons are a surprisingly thoughtful and introspective group.   Become a supporter of our show today either on Patreon or through PayPal! Thank you! http://www.patreon.com/thebodyofevidence/ https://www.paypal.com/donate?hosted_button_id=9QZET78JZWCZE   Email us your questions at thebodyofevidence@gmail.com.   Editor:    Robyn Flynn Theme music: "Fall of the Ocean Queen" by Joseph Hackl Rod of Asclepius designed by Kamil J. Przybos Chris' book, Does Coffee Cause Cancer?: https://ecwpress.com/products/does-coffee-cause-cancer   Obviously, Chris is not your doctor (probably). This podcast is not medical advice for you; it is what we call information. References: The FICEBO website: www.ficebo.com The original FIDELITY trial showing meniscectomy had no benefit: https://www.nejm.org/doi/full/10.1056/NEJMoa1305189 The recent 10-year follow-up data from FIDELITY: https://www.nejm.org/doi/full/10.1056/NEJMc2516079 The SIMPLICITY HTN-3 sham surgery trial on renal denervation: https://www.nejm.org/doi/full/10.1056/NEJMoa1402670 Max Planck's Principle: https://en.wikipedia.org/wiki/Planck%27s_principle

    47 min
4.6
out of 5
64 Ratings

About

Dr. Christopher Labos and guests use the body of evidence to go beyond science and medicine headlines and hype. All to help you develop your critical thinking skills so that when you google your symptoms, you won't believe you're going to die tomorrow. The Body of Evidence is your weekly dose of clarity on complex health topics and the often-sketchy medical information found online. Hosted by cardiologist Dr. Christopher Labos and featuring a rotating cast of co-hosts and guests, this podcast brings you engaging interviews, original reporting, and humour-filled commentaries to help you navigate the world of medicine. Episodes tackle everything from debunking misinformation to exploring the reality of certain conditions to the effectiveness of social media medical trends. With an extensive archive dating back to 2015,The Body of Evidence is your go-to source for understanding science and medicine and developing critical thinking about your health.

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