Peptide Show

Longr

Welcome to the world of Peptides. New episodes every Tuesday.

Episodes

  1. 1d ago

    Dylan Gemelli: Can you trust the peptides you’re buying?

    What happens when the people profiting from peptides have different motives from the people relying on them?  For the past 15 years, the fitness and biohacking educator and host of The Dylan Gemelli Podcast has watched peptides move from bodybuilding forums and research chemical sites into the mainstream. Then the market changed around him. GLP-1s propelled peptides into public consciousness. BPC-157 became one of the compounds most closely associated with the category. And an underground market expanded alongside them, where suppliers, testing and certificates of analysis can create an appearance of certainty that may not always be justified. Gemelli believes peptides have far more potential than the handful of compounds dominating the conversation. But he is equally concerned by what happens when consumers buy from unregulated suppliers, assume a COA proves quality, or trust that what is on the label is what is actually in the vial. He explains: ■ How peptides went from obscure research chemicals to the mainstream■ Why GLP-1s and BPC-157 have narrowed the public understanding of peptides■ Why a certificate of analysis does not necessarily prove what is actually in the vial■ What consumers should understand about underground suppliers, raw materials and peptide testing■ Why he believes peptides will become more widely accepted, and why he worries about who ultimately controls them Chapters (00:00) - Intro (02:09) - Fifteen years in peptides (09:17) - How peptides went mainstream (13:35) - The GLP-1 and BPC-157 problem (16:47) - Peptides beyond GLP-1s (19:18) - Protecting muscle on GLP-1s (22:11) - Are GLP-1s overprescribed? (23:12) - Inside the underground peptide market (23:56) - Where peptide raw materials come from (25:07) - Why COAs can mislead you (26:04) - Suppliers, Reddit and white-labelling (29:24) - Who controls the future of peptides? Watch the full episode on YouTube Further reading FDA: Concerns around unapproved GLP-1 drugs, foreign APIs, illegal online sales and products marketed as being for research purposes: FDA: Concerns with unapproved GLP-1 drugs  FDA: July 2026 Pharmacy Compounding Advisory Committee meeting covering BPC-157, KPV, TB-500, MOTS-c and other peptide-related bulk substances: FDA PCAC July 2026 meeting  Read the full transcript Follow Dylan Gemelli Instagram: Instagram.com/dylangemelli X: x.com/DylanGemelli YouTube: YouTube.com/@DylanGemelliBiohacking Website: DylanGemelli.com Follow Richard Skaife LinkedIn: https://www.linkedin.com/in/richardskaife/ Peptide Show Website: Peptide.Show The Peptide Show explores the science, medicine, business and people shaping the rapidly evolving world of peptides. Presented by Longr: longr.io Follow The Peptide Show for new episodes every Tuesday. This podcast is for informational and educational purposes only and does not constitute medical advice. Some compounds discussed in this episode are investigational, unapproved for the uses discussed, or subject to changing regulatory requirements.

    Dylan Gemelli: Can you trust the peptides you’re buying?
  2. Sep 8

    Dr Terry Dubrow: Peptides are about to change everything. Are we ready?

    What happens when millions of people want drugs their doctors can’t prescribe? Very few doctors become household names. Dr Terry Dubrow is one of them. For more than two decades, the board-certified plastic surgeon and star of Botched has sat at the intersection of medicine and popular culture, becoming one of the most recognizable doctors in America. Then peptides changed the direction of his career. Decades into an already established surgical career, Dr Dubrow went back to study, became board-certified in obesity medicine, and developed what he describes as an obsession with peptides, longevity and what could become the next frontier of medicine.  He believes peptides could transform healthcare. But as unapproved compounds move online, patients bypass doctors and regulation struggles to keep pace, he is warning that the same revolution could also produce a serious medical backlash.  He explains: ■ Why GLP-1s changed the direction of his career and pulled him into peptide medicine ■ Why he believes peptides could eventually change how we age■ Why retatrutide is already being accessed before FDA approval ■ Why pushing peptides outside the medical system could make them more dangerous, not less■ The peptide safety event he fears could trigger a major backlash Chapters (00:00) - Intro (02:07) - From GLP-1s to peptides (05:07) - Can peptides reverse aging? (07:54) - Peptides and the regulatory Wild West (09:59) - Retatrutide and the next GLP-1s (14:00) - Microdosing GLP-1s for longevity (16:14) - The biggest myths about peptides (18:12) - Why doctors need better peptide data (19:57) - The danger of unregulated peptides (21:52) - The future of peptides and longevity  Watch the full episode on YouTube   Further reading FDA: July 2026 Pharmacy Compounding Advisory Committee meeting covering BPC-157, TB-500, MOTS-c and other peptide-related bulk substances: FDA PCAC July 2026 meeting ClinicalTrials.gov: Phase 3 TRIUMPH-1 study of retatrutide in obesity and overweight: Retatrutide TRIUMPH-1 trial Read the full transcript   Follow Dr Terry Dubrow Instagram: Instagram.com/drdubrow X: x.com/DrDubrow Website: DrDubrow.com Follow Richard Skaife LinkedIn: https://www.linkedin.com/in/richardskaife/ The Peptide Show Website: Peptide.Show The Peptide Show explores the science, medicine, business and people shaping the rapidly evolving world of peptides. Presented by Longr: longr.io Follow The Peptide Show for new episodes every Tuesday. This podcast is for informational and educational purposes only and does not constitute medical advice. Some compounds discussed in this episode are investigational, unapproved for the uses discussed, or subject to changing regulatory requirements.

    Dr Terry Dubrow: Peptides are about to change everything. Are we ready?

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Welcome to the world of Peptides. New episodes every Tuesday.