This Week in Parasitism

Vincent Racaniello

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TWiP is a monthly netcast about eukaryotic parasites. Vincent Racaniello and Dickson Despommier, science Professors from Columbia University, deconstruct parasites, how they cause illness, and how you can prevent infections.

29/05

The wriggling diagnosis

TWiP solves the case of the 3 yo child, who recently immigrated to the US from Central America, in the ER with acute right lower quadrant abdominal pain and a rather active serpiginous wormlike 'thing' wiggling away in the child's appendix. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Hero: Rudolf Ludwig Carl Virchow (1821-1902) Letters read on TWiP 280 TWiP study – information and survey New Case 3 yo child who recently immigrated to the US from Central America is brought in to the ER with acute right lower quadrant abdominal pain. The mother is concerned about the pain as well as nausea and vomiting. This is acute and the ER provider is concerned that this might be an acute surgical emergency. They order an US in this child and they are surprised to see a rather active serpiginous wormlike 'thing' wiggling away in the child's appendix. I was sent the Ultrasound video which I really enjoyed. What to do? Become a patron of TWiP Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees

57 min
1/05

Tolling for hookworms

TWiP reviews a phase 2 clinical trial of a recombinant vaccine against N. americanus glutathione S-transferase-1, an enzyme that performs a crucial enzymatic step in hookworm blood feeding. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Phase 2 hookworm vaccine clinical trial (Lancet Inf Dis) Phase 2 Schistosoma vaccine clinical trial (Vaccines) TWiP study – information and survey Become a patron of TWiP Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees

51 min
24/04

Trichinella from eating bear eyeballs

TWiP solves the case of the male in his 20s from Hokkaido, Japan, who developed fatigue and rash, followed by fever and myalgia 6 days later, after eating a raw bear eyeball. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Hero: Sir Nicholas White (1951 – 2026) (Guardian, Lancet) Letters read on TWiP 278 TWiP study – information and survey New Case 3 yo child who recently immigrated to the US from Central America is brought in to the ER with acute right lower quadrant abdominal pain. The mother is concerned about the pain as well as nausea and vomiting. This is acute and the ER provider is concerned that this might be an acute surgical emergency. They order an US in this child and they are surprised to see a rather active serpiginous wormlike 'thing' wiggling away in the child's appendix. I was sent the Ultrasound video which I really enjoyed. What to do? Become a patron of TWiP Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees

56 min
21/04

Rif-ing on river blindness

TWiP 277: Rif-ing on river blindness April 21, 2026 TWiP reviews the global, regional, and national burden of Chagas disease, and comparison of doxycycline and rifampicin for the treatment of onchocerciasis. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Burden of Chagas' disease (Lancet Inf Dis) Doxycycline vs rifampicin in treatment of river blindness (Open For Inf Dis) The kissing bug by Daisy Hernandez TWiP study – information and survey Become a patron of TWiP Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees

1 h 4 min
23/03

Travel history is the key

TWiP solves the case of the man in his 60s experiencing weight loss, fatigue, and loss of appetite. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Hero: Bailey K. Ashford Letters read on TWiP 276 TWiP study – information and survey New Case Male in his 20s from Hokkaido, Japan, developed fatigue and rash, followed by fever and myalgia 6 days later. He was a group of five individuals on a hunting trip prior to this and reports that 3 friends are just fine but one other individual developed similar symptoms. He reports that they had been hunting the Ussuri brown bear, which is larger and more aggressive than the Asian black bear. They had been successful and all five of them had consumed well cooked bear meat. He does share that he is aware of infectious risk from eating bear and thus the meat was well cooked. He and the one fellow hunter who did get sick were unique in that they each ate one of the eye balls raw. This is a tradition that is felt to give the consumer the great vision that these animals are purported to have. Become a patron of TWiP Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees

1 h 17 min
12/03

Novel malaria vector control

TWiP reviews the effectiveness of long-lasting spatial repellent emanators against malaria in humanitarian crisis settings in northern Nigeria, and Dengue suppression by male Wolbachia-infected mosquitoes. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Spatial emanators for malaria control (Lancet Inf Dis) Dengue suppression with Wolbachia-infected mosquitoes (NEJM) Singapore Environmental Health Institute (TWiV 630) TWiP study – information and survey Become a patron of TWiP Send your questions and comments to twip@microbe.tv

42 min
17/02

Four tablets for bloating

TWiP solves the case of the 40 year old male who travels to India and develops intestinal bloating and diarrhea. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Hero: Glenn L. Hoffmann Fish and seafood consumption (Our World in Data) Wild fish vs aquaculture (Our World in Data) TWiP study – information and survey Become a patron of TWiP Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees

48 min
6/02

TIntestinal parasites in dogs

TWiP reviews intestinal parasites in dogs and their association with clinical manifestations of canine visceral leishmaniasis. Hosts: Vincent Racaniello, Daniel Griffin, and Christina Naula Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Join the MicrobeTV Discord server Intestinal parasites in dogs (Vet Parasitol) Zoonotic protozoal diseases of companion animals (Clin Micr Rev) Canine visceral leishmaniasis in stray and owned dogs in Brazil (Acta tropica) Zoonotic protozoal diseases of companion animals (Clin Micr Rev) Canine visceral leishmaniasis (Leish Vet, pdf) Immune Responses in leishmaniasis (Trop Med Inf Dis) Canine leishmaniasis in the US (Today's Vet Prac) TWiP study - information and survey Become a patron of TWiP Send your questions and comments to twip@microbe.tv Music by Ronald Jenkees

1 h 6 min

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TWiP is a monthly netcast about eukaryotic parasites. Vincent Racaniello and Dickson Despommier, science Professors from Columbia University, deconstruct parasites, how they cause illness, and how you can prevent infections.