Longevity Optimization with Kayla Barnes-Lentz

Kayla Barnes-Lentz

Maximizing Human Health and Performance. We discuss: optimal health, nutrition, high-performance, cognitive excellence, biohacking, longevity and more with top experts around the world. Hosted by Kayla Barnes-Lentz.

  1. 1 DAY AGO

    Dr. Laura Briden - This Is The Biggest Health Crisis Of Our Time

    Today I’m joined by Dr. Lara Briden, a naturopathic doctor, best-selling author, and internationally recognized expert in women’s hormones for a wide-ranging conversation on cycle health and why ovulation is a vital sign of wellbeing. We talked about how monthly ovulation creates hormones that support bones, metabolism, and brain function, and what happens when that rhythm is disrupted by stress, restrictive eating, or birth control. Dr. Briden explains why natural estradiol and progesterone are so protective, how they differ from synthetic hormones, and what that means for both younger women and women approaching perimenopause. She also shares her perspective on missing periods, hypothalamic amenorrhea, and the four functional types of PCOS, along with the growing role of insulin resistance in hormone imbalance. We talk about how to track ovulation, what lab markers to look for, and why restoring cycles is one of the most powerful steps for long-term health. Chapters 00:49 - Ovulation as a vital sign of female health 02:57 - Impact of hormonal birth control on ovulation and hormones 07:51 - Benefits of natural estrogen and progesterone 09:47 - Perimenopause and importance of hormones in young women 11:49 - Benefits of estradiol and progesterone 17:37 - Dysregulated or missing periods 19:50 - Anovulatory cycles and tracking ovulation 22:50 - Lag time for menstrual cycle disruption and recovery 26:50 - Differentiating between hypothalamic amenorrhea and PCOS 31:18 - Four different types of PCOS 36:25 - Lab markers for insulin resistance 58:53 - Recommendations for managing insulin-resistant PCOS Dr. Briden socials + website Website: ⁠https://www.larabriden.com/about/⁠  Instagram: ⁠@larabriden⁠ Kayla's social + website: Instagram: ⁠https://www.instagram.com/kaylabarnes/⁠ TikTok: ⁠https://www.tiktok.com/@femalelongevity⁠ Twitter: ⁠https://x.com/femalelongevity⁠  Website: ⁠https://www.kaylabarnes.com/⁠ Follow Her Female Protocol: ⁠https://www.protocol.kaylabarnes.com/⁠ Become a Member of Kayla's Female Longevity Membership: ⁠https://kayla-barnes-lentz.circle.so/checkout/become-a-member⁠

    1h 7m
  2. 11 SEPT

    The Diet Myth: Why “Healthy Eating” Is Making Women Sicker

    Brigid Titgemeier, a functional medicine dietitian and founder of Being Brigid Nutrition, has seen countless women walk into her clinic exhausted, bloated, and frustrated despite eating all the right foods. She knows that feeling firsthand, too. Instead of blaming willpower or cutting out everything you love, Brigid discovered how simple, personalized nutrition changes could completely shift energy, hormones, and mood. In this episode, she shares why common advice like “just eat clean” or “go low-carb” often backfires, and what really moves the needle when it comes to gut health, hormone balance, and long-term vitality. We also talked about the hype around weight-loss drugs, overlooked biomarkers that reveal hidden stress in the body, and why your microbiome might hold the biggest key to feeling better. If you’ve ever wondered why eating healthy doesn’t always feel healthy, this conversation will give you the clarity and hope you’ve been missing. Chapters 00:00 Introduction 00:02:59 - Introduction of Brigid Tegemeier 00:05:08 - The three biggest nutrition myths. 00:05:56 - Myth 1: Just eating a variety of whole foods is enough for improving overall health. 00:07:04 - Myth 2: A low carb lifestyle works well for every single person. 00:07:32 - Myth 3: The obsession with protein is always beneficial. 00:08:24 - Why individuals might not see results even if they're doing everything for their health. 00:15:09 - How long it should take to see results  00:18:15 - GLP1 medications for weight loss. 00:22:59 - Establishing a good baseline for diet, focusing on fiber diversity and prebiotic sources. 00:29:36 - Recommendations for protein intake for women. 00:30:35 - Carbohydrate intake and its impact on female hormones and stress response. 01:09:54 - Seed oils and the balance of Omega 6s to Omega 3s. Guest’s socials + website LinkedIn: https://www.linkedin.com/in/brigid-titgemeier-b437574b  Website: https://beingbrigid.com/  Instagram: @beingbrigid Kayla's social + website: Instagram: https://www.instagram.com/kaylabarnes/ TikTok: https://www.tiktok.com/@femalelongevity Twitter: https://x.com/femalelongevity  Website: https://www.kaylabarnes.com/ Follow Her Female Protocol: https://www.protocol.kaylabarnes.com/ Become a Member of Kayla's Female Longevity Membership: https://kayla-barnes-lentz.circle.so/checkout/become-a-member

    1h 15m
  3. 4 SEPT

    Dr. Matt Kaeberlein, PhD - Why We Age + Interventions to Slow Aging

    What if aging wasn’t just something that happens to us, but something science could actually slow down? That’s the question at the heart of today’s conversation with Dr. Matt Kaeberlein, who’s a leading scientist and longevity researcher at the University of Washington. Dr. Kaeberlein has spent decades decoding the biology of aging, from cellular mechanisms to practical strategies that could extend not just how long we live, but how well we live. In this episode, we talked about surprising connections between aging and brain health, and looked into the research around lithium and Alzheimer’s to see what the latest science is telling us about extending healthspan. It is an informative discussion on whether aging itself can be slowed or reversed. If you’re curious about how close we really are to changing the rules of aging, this could be worth a watch. Chapters: 00:00 – Introduction & The Biology of Aging Across Species 10:57 – The Struggles of Change, GLP-1 Drugs & The Power of Sleep 14:33 – The Hallmarks of Aging 21:52 – Funding Issues 23:22 – The Truth About Anti-Aging Drugs 27:22 – Biological Age Testing  48:23 – Biomarkers, Advanced Testing & The Limits of Diagnostics 01:02:50 – Micronutrient Testing and Supplements 01:07:11 –  NAD, Smarter Longevity Choices 01:18:05 –  Lithium’s Secret Role in Aging and Memory Loss 01:27:00 – Foundations of Longevity 01:57:37 - Ovarian Aging 02:01:02 – Closing Thoughts & Where to Find the Guest  Guest’s socials + website: YouTube: https://www.youtube.com/@optispan X: https://x.com/mkaeberlein?lang=en Website: https://www.optispan.life/  Kayla's social + website: Instagram: https://www.instagram.com/kaylabarnes/ TikTok: https://www.tiktok.com/@femalelongevity Twitter: https://x.com/femalelongevity  Website: https://www.kaylabarnes.com/ Follow Her Female Protocol: https://www.protocol.kaylabarnes.com/ Become a Member of Kayla's Female Longevity Membership: https://kayla-barnes-lentz.circle.so/checkout/become-a-member

    2h 2m
  4. 28 AUG

    The Fertility Formula with Dr. Natalie Crawford

    Join us in this powerful episode as we sit down with Dr. Natalie Crawford, a double board-certified OB/GYN and reproductive endocrinologist. We explore her personal journey with recurrent pregnancy loss, the rising rates of infertility, and the impact of inflammation, toxins, and lifestyle on reproductive health. Discover how Dr. Crawford is reshaping fertility care and empowering women to understand their bodies, advocate for their health, and make informed choices about their future. Chapters: 00:00 – Introduction 02:15 – Dr. Crawford’s personal fertility journey & miscarriages 07:07 – Discovering inflammation, toxins & celiac connection 09:56 – Rising infertility rates & sperm count decline12:18 – Cycle tracking, wearables & hormone testing 15:11 – AMH testing & why it’s controversial 20:14 – Fertility testing, anatomy & semen analysis 26:26 – Patient stories & whole-body fertility approach 34:17 – Environmental toxins & endocrine disruptors 40:09 – Egg quality, biological age & lifestyle factors 46:28 – Advanced strategies: red light therapy, IVF testing, add-ons 56:00 – Birth control myths & fertility impact 01:04:09 – Menopause, genetics & shifting timelines 01:12:01 – Fertility myths & misconceptions 01:16:07 – Prenatal vitamins, folate vs. methylfolate debate 01:21:18 – PCOS explained & why diagnosis matters 01:28:36 – Closing thoughts, book & where to find Dr. Crawford *Dr. Natalie Crawford's Socials:*YouTube: https://www.youtube.com/@NatalieCrawfordMD/videosIG: https://www.instagram.com/nataliecrawfordmdTikTok: https://www.tiktok.com/@UCRZamIB-DWuVPJuc0bKhwzg Website: https://www.nataliecrawfordmd.com/X: https://x.com/ncrawfordmd?lang=enFacebook: https://www.facebook.com/nataliecrawfordmd/Podcast: https://podcasts.apple.com/us/podcast/as-a-woman/id1449553339*Kayla's social + website:*Instagram: https://www.instagram.com/kaylabarnes/TikTok: https://www.tiktok.com/@femalelongevityTwitter: https://x.com/femalelongevityWebsite: https://www.kaylabarnes.comFollow Her Female Protocol: https://www.protocol.kaylabarnes.comBecome a Member of Kayla's Female Longevity Membership: https://kayla-barnes-lentz.circle.so/..

    1h 31m
  5. 21 AUG

    Dr. Bill Rawls, MD - Cellular Healing: Lyme, Mold & The Chronic Illness Solution

    Today I’m joined by Dr. Bill Rawls, a board-certified physician and bestselling author, for a wide-ranging conversation on chronic illness, healing, and what it really takes to protect long-term health. We dive into the challenges people face when conventional medicine falls short, the role of lifestyle and environment in recovery, and the surprising power of natural approaches to restore balance in the body.Dr. Rawls also shares insights on resilience, aging, and why true wellness depends on going deeper than symptom management. If you’ve ever struggled with confusing health issues or wondered why the body sometimes fails to heal, this episode offers clarity, empowerment, and tools you can begin applying right away. Chapters:00:00 – Introduction02:03 – When Medicine Doesn’t Have the Answers07:12 – A Personal Turning Point13:14 – Rethinking What “Chronic” Really Means19:22 – The Body’s Hidden Defenses24:55 – How Stress Shapes Illness31:20 – A Smarter Way to Approach Healing38:04 – Restoring Balance Naturally44:50 – Building Resilience for the Long TermDr. Bill Rawls IG + website:IG: https://www.instagram.com/rawlsmd/?hl=enWebsite: https://rawlsmd.com/Resources: https://rawlsmd.com/resources/ Kayla's social + website:Instagram: https://www.instagram.com/kaylabarnes/TikTok: https://www.tiktok.com/@femalelongevityTwitter: https://x.com/femalelongevityWebsite: https://www.kaylabarnes.comFollow Her Female Protocol: https://www.protocol.kaylabarnes.comBecome a Member of Kayla's Female Longevity Membership: ;https://kayla-barnes-lentz.circle.so/checkout/become-a-member

    1h 41m
  6. 7 AUG

    Dr. Brooke Stubbs - Foundational Female Health Pillars

    Today I’m joined by Dr. Brooke Stubbs, a double board-certified physician in internal and lifestyle medicine, for a deep dive into inflammation, what drives it, how it shows up in the body, and why so many women are silently affected by it. We explore how gut dysfunction, hormone imbalances, poor sleep, and emotional stress contribute to chronic symptoms like fatigue, bloating, brain fog, and burnout. Dr. Stubbs shares why inflammation is often overlooked in conventional care—and how a functional, root-cause approach can lead to lasting healing.She also explains how food, movement, stress management, and environment can either fuel or reduce disease over time.If you’ve ever felt dismissed by the medical system or frustrated by vague symptoms, this conversation offers clarity, empowerment, and science-backed tools to take your health into your own hands.This episode is brought to you by Seed. Save 25% off Seed: https://seed.com/daily-synbiotic?utm_source=ambassador&utm_medium=podcast&utm_campaign=kaylabarnes&utm_term=25p&promo_code=KAYLABARNES25Chapters: 00:00 – Introduction02:57 – Women Are Being Misdiagnosed (Here’s Why)09:10 – How Ultra-Processed Foods Hijack Your Biology15:05 – The Gut-Brain-Immune Axis Is Real (And Powerful)21:23 – Environmental Toxins Are Disrupting Your Hormones27:02 – Longevity Medicine Isn’t Just for Men33:10 – Debunking “Plant-Based Is Always Healthier”39:18 – Your Nervous System Is a Missing Piece44:56 – What Dr. Stubbs Actually Eats in a Day_______________Dr. Brooke Stubbs + WebsiteIG:   / brookiestubbsmd  Website: https://brookestubbsmd.com/Kayla Socials + WebsiteInstagram:   / kaylabarnes  TikTok:   / femalelongevity  Twitter: https://x.com/femalelongevityWebsite: https://www.kaylabarnes.comFollow Her Female Protocol: https://www.protocol.kaylabarnes.comBecome a Member of Kayla's Female Longevity Membership: https://kayla-barnes-lentz.circle.so/checkout/become-a-memberkayla-barnes-lentz.circle.so/checkout/become-a-member

    55 min
  7. 31 JUL

    Exploring Metabolic Health with Nick Norwitz, MD, PhD

    In this conversation, I sit down with Nick to unpack the deeper science behind GLP-1s and metabolic health. We explore how compounds like Tirzepatide and GLP-1 agonists go beyond weight loss, influencing everything from cardiovascular elasticity and neuroinflammation to mood, cognition, and gut-brain signaling. We also discuss lesser-known drivers of real change, like adiponectin, MPO, and the surprising effects of statins on inflammation.But the conversation doesn’t stop with human health. We dive into the behavioral power of the microbiome, how dogs might reduce childhood allergies, and whether AI can actually translate what your pet is thinking. If you’re curious about fat loss, brain health, and the future of metabolic science, this episode offers a perspective you won’t find anywhere else.*Chapters:*0:00 – Meet Dr. Nick: From Patient to Pioneer06:50 – The Problem with "Evidence-Based Medicine"10:15 – Why Nick Left the Medical System13:10 – Can YouTube Have a Bigger Impact Than Hospitals?16:30 – What Is Metabolic Health & Why Does It Matter?19:00 – Mental Health, Depression & Metabolism24:15 – Brain Hacks That Actually Work40:00 – Improving Metabolic Flexibility Naturally46:00 – Gut-Brain Connection & Fiber Myths*Nick's Socials + Website*IG: https://www.linkedin.com/in/nicknorwitz/Youtube channel: https://www.youtube.com/channel/UCLTZUJSEulehPtF_ytFiU_AWebsite: https://www.nicknorwitz.com*Kayla's Socials + Website*Instagram: https://www.instagram.com/kaylabarnes/TikTok: https://www.tiktok.com/@femalelongevityTwitter: https://x.com/femalelongevityWebsite: https://www.kaylabarnes.comFollow Her Female Protocol: https://www.protocol.kaylabarnes.comBecome a Member of Kayla's Female Longevity Membership: https://kayla-barnes-lentz.circle.so/checkout/become-a-member

    1h 9m

About

Maximizing Human Health and Performance. We discuss: optimal health, nutrition, high-performance, cognitive excellence, biohacking, longevity and more with top experts around the world. Hosted by Kayla Barnes-Lentz.

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