Cardio Pod: Heart of the Matter

Heart Failure Collaboratory
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Introducing Heart of the Matter Cardio Pod. High-level conversations to foster conversation, collaboration, and communication around the ecosystem of cardiovascular research.

  1. 13 Aug

    The Stories Behind the People with Dr. Robert Califf

    In this inaugural episode of The Stories Behind the People, host Dr. Christopher O'Connor sits down with Dr. Robert Califf for a candid conversation that goes beyond medicine. Together, they explore Dr. Califf's personal journey, the defining moments that shaped his life, and the experiences that influenced his leadership, values, and extraordinary career. From personal reflections to professional milestones, this episode offers a rare glimpse into the man behind one of the most influential voices in cardiovascular medicine.

    The Stories Behind the People with Dr. Robert Califf

  2. 22 Jul

    CKM Score

    In this episode, host Dr. Christopher O'Connor is joined by Dr. Carine Hamo, Dr. Ankeet Bhatt, and Dr. Javed Butler to discuss the CKM Score and the quantitative methods that are beginning to transform how we design and conduct clinical trials, as well as how they can improve everyday clinical practice.

    CKM Score

  3. 1 Jul

    Evaluating and Accounting for Body Weight and Obesity / Adjusting for Body Weight

    In this episode, host Dr. Christopher O'Connor is joined by Drs. Carine Hamo, Ankeet Bhatt, Joan Lindenfeld, and Martin Cowie to discuss the importance of evaluating and accounting for body weight and obesity in heart failure research and care. The panel explores key considerations for adjusting for body weight, interpreting clinical outcomes, and ensuring that trial design and treatment strategies accurately reflect the impact of obesity on patients with heart failure.

    Evaluating and Accounting for Body Weight and Obesity / Adjusting for Body Weight

  4. 10 Jun

    Derisking Phase II Clinical Trials in HF

    In this episode, host Christopher O'Connor sits down with Scott D. Solomon, Ellis Unger, Janet Wittes, Michael Felker, Ben Saville, Douglas Mann, and Fady Malik to discuss how to design Phase II clinical trials that generate meaningful data, reduce uncertainty, and improve the chances of success in later-stage studies.

    Derisking Phase II Clinical Trials in HF

  5. 20 May

    Class Effect considerations in devices

    In this episode, Host Dr. Christopher O'Connor and his guests, Dr, Joann Lindenfeld, Dr. Mitchell Psotka, Dr. Minnow Walsh and Dr. William Abraham, discuss class effect considerations in devices.

    Class Effect considerations in devices

  6. 29 Apr

    Crossover designs and event driven trials in devices

    In this episode, host Christopher O’Connor and his colleagues discuss device trials and how they differ from drug trials. The conversation focuses on how device trials can be improved and how to advance device development overall.

    Crossover designs and event driven trials in devices

  7. 8 Apr

    Best Practices for Site-Based Research (Part 3)

    Host Christopher O’Connor, MD is joined by Jana Svetlichnaya, MD; Anu Lala-Trindade, MD; and Marshall Brinkley, MD to unpack the challenges of site-based research. This episode dives into the barriers, obstacles, and opportunities investigators face—and what it truly takes to build and sustain a successful research site.

    Best Practices for Site-Based Research (Part 3)

  8. 18 Mar

    Recurrent Events VS. Time to First Event Analysis

    This episode explores two different ways of analyzing outcomes in clinical trial and longitudinal studies in cardiovascular and heart failure research.

    Recurrent Events VS. Time to First Event Analysis
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Introducing Heart of the Matter Cardio Pod. High-level conversations to foster conversation, collaboration, and communication around the ecosystem of cardiovascular research.

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